Stephen C Blacklow

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 33

Top Topics

Genome Wide Association

Transcription Factor

Dna Damage Response

Top Venues

Nature communications

bioRxiv : the preprint server for biology

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Kian Hong Kock, Patrick K Kimes, Stephen S Gisselbrecht, Sachi Inukai, Sabrina K Phanor, James T Anderson, Gayatri Ramakrishnan, Colin H Lipper, Dongyuan Song, Jesse V Kurland, Julia M Rogers, Raehoon Jeong, Stephen C Blacklow, Rafael A Irizarry, Martha L Bulyk
DNA binding analysis of rare variants in homeodomains reveals homeodomain specificity-determining residues. Nature communications 15 (1) (2024)
Ruili Cao, Oren Gozlan, Lena Tveriakhina, Haixia Zhou, Hanjie Jiang, Philip A Cole, Jon C Aster, David Sprinzak, Stephen C Blacklow
Structural Requirements for Activity of Mind bomb1 in Notch Signaling. bioRxiv : the preprint server for biology (2024)
Kian Hong Kock, Patrick K Kimes, Stephen S Gisselbrecht, Sachi Inukai, Sabrina K Phanor, James T Anderson, Gayatri Ramakrishnan, Colin H Lipper, Dongyuan Song, Jesse V Kurland, Julia M Rogers, Raehoon Jeong, Stephen C Blacklow, Rafael A Irizarry, Martha L Bulyk
DNA binding analysis of rare variants in homeodomains reveals homeodomain specificity-determining residues. Nature communications 15 (1) (2024)
Ruili Cao, Oren Gozlan, Lena Tveriakhina, Haixia Zhou, Hanjie Jiang, Philip A Cole, Jon C Aster, David Sprinzak, Stephen C Blacklow
Structural Requirements for Activity of Mind bomb1 in Notch Signaling. bioRxiv : the preprint server for biology (2024)
Ruili Cao, Oren Gozlan, Lena Tveriakhina, Haixia Zhou, Hanjie Jiang, Philip A Cole, Jon C Aster, David Sprinzak, Stephen C Blacklow
Structural Requirements for Activity of Mind bomb1 in Notch Signaling. bioRxiv : the preprint server for biology (2024)
Kian Hong Kock, Patrick K Kimes, Stephen S Gisselbrecht, Sachi Inukai, Sabrina K Phanor, James T Anderson, Gayatri Ramakrishnan, Colin H Lipper, Dongyuan Song, Jesse V Kurland, Julia M Rogers, Raehoon Jeong, Stephen C Blacklow, Rafael A Irizarry, Martha L Bulyk
DNA binding analysis of rare variants in homeodomains reveals homeodomain specificity-determining residues. Nature communications 15 (1) (2024)
Kian Hong Kock, Patrick K Kimes, Stephen S Gisselbrecht, Sachi Inukai, Sabrina K Phanor, James T Anderson, Gayatri Ramakrishnan, Colin H Lipper, Dongyuan Song, Jesse V Kurland, Julia M Rogers, Raehoon Jeong, Stephen C Blacklow, Rafael A Irizarry, Martha L Bulyk
DNA binding analysis of rare variants in homeodomains reveals homeodomain specificity-determining residues. Nature communications 15 (1) (2024)
Daniel T D Jones, Andrew N Dates, Shaun D Rawson, Maggie M Burruss, Colin H Lipper, Stephen C Blacklow
Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling. Nature communications 14 (1) (2023)
Daniel T D Jones, Andrew N Dates, Shaun D Rawson, Maggie M Burruss, Colin H Lipper, Stephen C Blacklow
Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling. Nature communications 14 (1) (2023)
Ruili Cao, Daniel Td Jones, Li Pan, Shumei Wang, Shaun Rawson, Jon C Aster, Stephen C Blacklow
Molecular Mechanism of PP2A/B55α Inhibition by IER5. bioRxiv : the preprint server for biology (2023)
Daniel T D Jones, Andrew N Dates, Shaun D Rawson, Maggie M Burruss, Colin H Lipper, Stephen C Blacklow
Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling. Nature communications 14 (1) (2023)
Alexandre Pj Martin, Gary A Bradshaw, Robyn J Eisert, Emily D Egan, Lena Tveriakhina, Julia M Rogers, Andrew N Dates, Gustavo Scanavachi, Jon C Aster, Tomas Kirchhausen, Marian Kalocsay, Stephen C Blacklow
A spatiotemporal Notch interaction map from plasma membrane to nucleus. Science signaling 16 (796) (2023)
Katherine J Susa, Gary A Bradshaw, Robyn J Eisert, Charlotte M Schilling, Marian Kalocsay, Stephen C Blacklow, Andrew C Kruse
A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation. bioRxiv : the preprint server for biology (2023)
Daniel T D Jones, Andrew N Dates, Shaun D Rawson, Maggie M Burruss, Colin H Lipper, Stephen C Blacklow
Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling. Nature communications 14 (1) (2023)
Lena Tveriakhina, Gustavo Scanavachi, Emily D Egan, Ricardo Bango Da Cunha Correia, Alexandre Pj Martin, Julia M Rogers, Jeremy S Yodh, Jon C Aster, Tomas Kirchhausen, Stephen C Blacklow
Temporal Dynamics and Stoichiometry in Notch Signaling - from Notch Synaptic Complex Formation to NICD Nuclear Entry. bioRxiv : the preprint server for biology (2023)
Anamarija Pfeiffer, Giulia Franciosa, Marie Locard-Paulet, Ilaria Piga, Kristian Reckzeh, Vidyasiri Vemulapalli, Stephen C Blacklow, Kim Theilgaard-Mönch, Lars Juhl Jensen, Jesper Velgaard Olsen
Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD-Driven AML. Cancer research 82 (11) (2022)
Bassma Khamaisi, Vincent C Luca, Stephen C Blacklow, David Sprinzak
Functional Comparison between Endogenous and Synthetic Notch Systems. ACS synthetic biology 11 (10) (2022)
David Gonzalez-Perez, Satyajit Das, Daniel Antfolk, Hadia S Ahsan, Elliot Medina, Carolyn E Dundes, Rayyan T Jokhai, Emily D Egan, Stephen C Blacklow, Kyle M Loh, Paulo C Rodriguez, Vincent C Luca
Affinity-matured DLL4 ligands as broad-spectrum modulators of Notch signaling. Nature chemical biology (2022)
Ariel J Ben-Sasson, Joseph L Watson, William Sheffler, Matthew Camp Johnson, Alice Bittleston, Logeshwaran Somasundaram, Justin Decarreau, Fang Jiao, Jiajun Chen, Ioanna Mela, Andrew A Drabek, Sanchez M Jarrett, Stephen C Blacklow, Clemens F Kaminski, Greg L Hura, James J De Yoreo, Justin M Kollman, Hannele Ruohola-Baker, Emmanuel Derivery, Julien S Baker
Design of biologically active binary protein 2D materials. Nature 589 (7842) (2021)
Vidyasiri Vemulapalli, Lily A Chylek, Alison Erickson, Anamarija Pfeiffer, Khal-Hentz Gabriel, Jonathan LaRochelle, Kartik Subramanian, Ruili Cao, Kimberley Stegmaier, Morvarid Mohseni, Matthew J LaMarche, Michael G Acker, Peter Karl Sorger, Steven P Gygi, Stephen C Blacklow
Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling. eLife 10 (2021)
Vidyasiri Vemulapalli, Katherine Aleisha Donovan, Tom C M Seegar, Julia M Rogers, Munhyung Bae, Ryan J Lumpkin, Ruili Cao, Matthew T Henke, Soumya S Ray, Eric S Fischer, Gregory D Cuny, Stephen C Blacklow
Targeted Degradation of the Oncogenic Phosphatase SHP2. Biochemistry 60 (34) (2021)
Katherine J Susa, Shaun Rawson, Andrew C Kruse, Stephen C Blacklow
Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81. Science (New York, N.Y.) 371 (6526) (2021)
Arijit A Adhikari, Tom C M Seegar, Scott B Ficarro, Megan D McCurry, Deepti Ramachandran, Lina Yao, Snehal N Chaudhari, Sula Ndousse-Fetter, Alexander S Banks, Jarrod A Marto, Stephen C Blacklow, A Sloan Devlin
Development of a covalent inhibitor of gut bacterial bile salt hydrolases. Nature chemical biology 16 (3) (2020)
Julia M Rogers, Bingqian Guo, Emily D Egan, Jon C Aster, Karen Adelman, Stephen C Blacklow
MAML1-Dependent Notch-Responsive Genes Exhibit Differing Cofactor Requirements for Transcriptional Activation. Molecular and cellular biology 40 (11) (2020)
Li Pan, Madeleine E Lemieux, Tom Thomas, Julia M Rogers, Colin H Lipper, Winston Lee, Carl Johnson, Lynette M Sholl, Andrew P South, Jarrod A Marto, Guillaume O Adelmant, Stephen C Blacklow, Jon C Aster
IER5, a DNA damage response gene, is required for Notch-mediated induction of squamous cell differentiation. eLife 9 (2020)
Katherine J Susa, Tom Cm Seegar, Stephen C Blacklow, Andrew C Kruse
A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking. eLife 9 (2020)
Sanchez M Jarrett, Tom C M Seegar, Mark Andrews, Guillaume Adelmant, Jarrod A Marto, Jon C Aster, Stephen C Blacklow
Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling. Science signaling 12 (606) (2019)
Tom Cm Seegar, Stephen C Blacklow
Domain integration of ADAM family proteins: Emerging themes from structural studies. Experimental biology and medicine (Maywood, N.J.) 244 (17) (2019)
Andrew A Drabek, Joseph J Loparo, Stephen C Blacklow
A Flow-Extension Tethered Particle Motion Assay for Single-Molecule Proteolysis. Biochemistry 58 (20) (2019)
Jonathan R LaRochelle, Michelle Fodor, Vidyasiri Vemulapalli, Morvarid Mohseni, Ping Wang, Travis Stams, Matthew J LaMarche, Rajiv Chopra, Michael G Acker, Stephen C Blacklow
Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition. Nature communications 9 (1) (2018)
Kostandin V Pajcini, Lanwei Xu, Lijian Shao, Jelena Petrovic, Karol Palasiewicz, Yumi Ohtani, Will Bailis, Curtis Lee, Gerald B Wertheim, Rajeswaran Mani, Natarajan Muthusamy, Yunlei Li, Jules P P Meijerink, Stephen C Blacklow, Robert B Faryabi, Sara Cherry, Warren S Pear
MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia. Science signaling 10 (505) (2017)
Sung Hee Choi, Eric Severson, Warren S Pear, Xiaole S Liu, Jon C Aster, Stephen C Blacklow
The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia. PloS one 12 (10) (2017)
Eric A Severson, Kelly L Arnett, Hongfang Wang, Chongzhi Zang, Len Taing, Hudan Liu, Warren S Pear, X Shirley Liu, Stephen C Blacklow, Jon C Aster
Genome-wide identification and characterization of Notch transcription complex-binding sequence-paired sites in leukemia cells. Science signaling 10 (477) (2017)