Riekelt H L Houtkooper (Riekelt H Houtkooper)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 52

Top Topics

Postmenopausal Women

Hypertrophic Cardiomyopathy

Top Venues

EMBO molecular medicine

Circulation. Genomic and precision medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Edgar E Nollet, Maike Schuldt, Vasco Sequeira, Aleksandra Binek, Thang V Pham, Stephan A C Schoonvelde, Mark Jansen, Bauke V Schomakers, Michel van Weeghel, Frederic M Vaz, Riekelt H L Houtkooper, Jennifer E Van Eyk, Connie R Jiménez, Michelle Michels, Kenneth C Bedi, Kenneth B Margulies, Cristobal G Dos Remedios, Diederik W D Kuster, Jolanda van der Velden
Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy. Circulation. Genomic and precision medicine 17 (3) (2024)
Arwen W Gao, Gaby El Alam, Yunyun Zhu, Weisha Li, Elena Katsyuba, Jonathan Sulc, Terytty Y Li, Xiaoxu Li, Katherine A Overmyer, Amelia Lalou, Laurent Mouchiroud, Maroun Bou Sleiman, Matteo Cornaglia, Jean-David Morel, Riekelt H L Houtkooper, Joshua J Coon, Johan Auwerx
High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan. bioRxiv : the preprint server for biology (2024)
Zhuqing Liang, Tyler Ralph-Epps, Michael W Schmidtke, Pablo Lazcano, Simone W Denis, Mária Balážová, Mohamed Chakkour, Sanaa Hazime, Mindong Ren, Michael Schlame, Riekelt H L Houtkooper, Miriam L Greenberg
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells. bioRxiv : the preprint server for biology (2024)
Georges E Janssens, Marte Molenaars, Katharina Herzog, Lotte Grevendonk, Carlijn M E Remie, Martin A T Vervaart, Hyung L Elfrink, Eric J M Wever, Bauke V Schomakers, Simone W Denis, Hans R Waterham, Mia L Pras-Raves, Michel van Weeghel, Antoine H C van Kampen, Alessandra Tammaro, Loes M Butter, Sanne van der Rijt, Sandrine Florquin, Aldo Jongejan, Perry D Moerland, Joris Hoeks, Patrick Schrauwen, Frederic M Vaz, Riekelt H L Houtkooper
A conserved complex lipid signature marks human muscle aging and responds to short-term exercise. Nature aging (2024)
Edgar E Nollet, Maike Schuldt, Vasco Sequeira, Aleksandra Binek, Thang V Pham, Stephan A C Schoonvelde, Mark Jansen, Bauke V Schomakers, Michel van Weeghel, Frederic M Vaz, Riekelt H L Houtkooper, Jennifer E Van Eyk, Connie R Jiménez, Michelle Michels, Kenneth C Bedi, Kenneth B Margulies, Cristobal G Dos Remedios, Diederik W D Kuster, Jolanda van der Velden
Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy. Circulation. Genomic and precision medicine 17 (3) (2024)
Georges E Janssens, Marte Molenaars, Katharina Herzog, Lotte Grevendonk, Carlijn M E Remie, Martin A T Vervaart, Hyung L Elfrink, Eric J M Wever, Bauke V Schomakers, Simone W Denis, Hans R Waterham, Mia L Pras-Raves, Michel van Weeghel, Antoine H C van Kampen, Alessandra Tammaro, Loes M Butter, Sanne van der Rijt, Sandrine Florquin, Aldo Jongejan, Perry D Moerland, Joris Hoeks, Patrick Schrauwen, Frederic M Vaz, Riekelt H L Houtkooper
A conserved complex lipid signature marks human muscle aging and responds to short-term exercise. Nature aging 4 (5) (2024)
Edgar E Nollet, Maike Schuldt, Vasco Sequeira, Aleksandra Binek, Thang V Pham, Stephan A C Schoonvelde, Mark Jansen, Bauke V Schomakers, Michel van Weeghel, Frederic M Vaz, Riekelt H L Houtkooper, Jennifer E Van Eyk, Connie R Jiménez, Michelle Michels, Kenneth C Bedi, Kenneth B Margulies, Cristobal G Dos Remedios, Diederik W D Kuster, Jolanda van der Velden
Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy. Circulation. Genomic and precision medicine (2024)
Arwen W Gao, Gaby El Alam, Yunyun Zhu, Weisha Li, Elena Katsyuba, Jonathan Sulc, Terytty Y Li, Xiaoxu Li, Katherine A Overmyer, Amelia Lalou, Laurent Mouchiroud, Maroun Bou Sleiman, Matteo Cornaglia, Jean-David Morel, Riekelt H L Houtkooper, Joshua J Coon, Johan Auwerx
High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan. bioRxiv : the preprint server for biology (2024)
Marit Schwantje, Signe Mosegaard, Suzan J G Knottnerus, Jan Bert van Klinken, Ronald J Wanders, Henk van Lenthe, Jill Hermans, Lodewijk IJlst, Simone W Denis, Yorrick R J Jaspers, Sabine A Fuchs, Riekelt H L Houtkooper, Sacha Ferdinandusse, Frederic M Vaz
Tracer-based lipidomics enables the discovery of disease-specific candidate biomarkers in mitochondrial β-oxidation disorders. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (4) (2024)
Edgar E Nollet, Maike Schuldt, Vasco Sequeira, Aleksandra Binek, Thang V Pham, Stephan A C Schoonvelde, Mark Jansen, Bauke V Schomakers, Michel van Weeghel, Frederic M Vaz, Riekelt H L Houtkooper, Jennifer E Van Eyk, Connie R Jiménez, Michelle Michels, Kenneth C Bedi, Kenneth B Margulies, Cristobal G Dos Remedios, Diederik W D Kuster, Jolanda van der Velden
Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy. Circulation. Genomic and precision medicine 17 (3) (2024)
Zhuqing Liang, Tyler Ralph-Epps, Michael W Schmidtke, Pablo Lazcano, Simone W Denis, Mária Balážová, Mohamed Chakkour, Sanaa Hazime, Mindong Ren, Michael Schlame, Riekelt H L Houtkooper, Miriam L Greenberg
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells. bioRxiv : the preprint server for biology (2024)
Georges E Janssens, Marte Molenaars, Katharina Herzog, Lotte Grevendonk, Carlijn M E Remie, Martin A T Vervaart, Hyung L Elfrink, Eric J M Wever, Bauke V Schomakers, Simone W Denis, Hans R Waterham, Mia L Pras-Raves, Michel van Weeghel, Antoine H C van Kampen, Alessandra Tammaro, Loes M Butter, Sanne van der Rijt, Sandrine Florquin, Aldo Jongejan, Perry D Moerland, Joris Hoeks, Patrick Schrauwen, Frederic M Vaz, Riekelt H L Houtkooper
A conserved complex lipid signature marks human muscle aging and responds to short-term exercise. Nature aging 4 (5) (2024)
Arthur A Bergen, Mark Jn Buijs, Anneloor L M A Ten Asbroek, Berith M Balfoort, Camiel Jf Boon, null null, Marion M Brands, Ronald Ja Wanders, Clara Dm van Karnebeek, Riekelt H L Houtkooper
Vision on gyrate atrophy: why treat the eye? EMBO molecular medicine (2023)
Arthur A Bergen, Mark Jn Buijs, Anneloor L M A Ten Asbroek, Berith M Balfoort, Camiel Jf Boon, null null, Marion M Brands, Ronald Ja Wanders, Clara Dm van Karnebeek, Riekelt H L Houtkooper
Vision on gyrate atrophy: why treat the eye? EMBO molecular medicine 16 (1) (2023)
Arthur A Bergen, Mark Jn Buijs, Anneloor L M A Ten Asbroek, Berith M Balfoort, Camiel Jf Boon, null null, Marion M Brands, Ronald Ja Wanders, Clara Dm van Karnebeek, Riekelt H L Houtkooper
Vision on gyrate atrophy: why treat the eye? EMBO molecular medicine 16 (1) (2023)
Arthur A Bergen, Mark Jn Buijs, Anneloor L M A Ten Asbroek, Berith M Balfoort, Camiel Jf Boon, null null, Marion M Brands, Ronald Ja Wanders, Clara Dm van Karnebeek, Riekelt H L Houtkooper
Vision on gyrate atrophy: why treat the eye? EMBO molecular medicine (2023)
Arthur A Bergen, Mark Jn Buijs, Anneloor L M A Ten Asbroek, Berith M Balfoort, Camiel Jf Boon, null null, Marion M Brands, Ronald Ja Wanders, Clara Dm van Karnebeek, Riekelt H L Houtkooper
Vision on gyrate atrophy: why treat the eye? EMBO molecular medicine 16 (1) (2023)
Myrthe A J Smits, Bauke V Schomakers, Michel van Weeghel, Eric J M Wever, Rob C I Wüst, Frederike Dijk, Georges E Janssens, Mariëtte Goddijn, Sebastiaan Mastenbroek, Riekelt H L Houtkooper, Geert Hamer
Human ovarian aging is characterized by oxidative damage and mitochondrial dysfunction. Human reproduction (Oxford, England) (2023)
Arthur A Bergen, Mark Jn Buijs, Anneloor L M A Ten Asbroek, Berith M Balfoort, Camiel Jf Boon, null null, Marion M Brands, Ronald Ja Wanders, Clara Dm van Karnebeek, Riekelt H L Houtkooper
Vision on gyrate atrophy: why treat the eye? EMBO molecular medicine 16 (1) (2023)
Georges E Janssens, Lotte Grevendonk, Ruben Zapata Perez, Bauke V Schomakers, Johan de Vogel-van den Bosch, Jan M W Geurts, Michel van Weeghel, Patrick Schrauwen, Riekelt H L Houtkooper, Joris Hoeks
Healthy aging and muscle function are positively associated with NAD + abundance in humans. Nature aging 2 (3) (2022)
Tineke A de Jong, Johanna F Semmelink, Simone W Denis, Janne W Bolt, Mario Maas, Marleen G H van de Sande, Riekelt H L Houtkooper, Lisa G M van Baarsen
Lower Metabolic Potential and Impaired Metabolic Flexibility in Human Lymph Node Stromal Cells from Patients with Rheumatoid Arthritis. Cells 12 (1) (2022)
Tineke A de Jong, Johanna F Semmelink, Simone W Denis, Janne W Bolt, Mario Maas, Marleen G H van de Sande, Riekelt H L Houtkooper, Lisa G M van Baarsen
Lower Metabolic Potential and Impaired Metabolic Flexibility in Human Lymph Node Stromal Cells from Patients with Rheumatoid Arthritis. Cells 12 (1) (2022)
Timon A Bloedjes, Guus de Wilde, Gerarda H Khan, Timothy Cody Ashby, John D Shaughnessy, Fenghuang Zhan, Riekelt H L Houtkooper, Richard J Bende, Carel J M van Noesel, Marcel Spaargaren, Jeroen E J Guikema
AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity. Blood advances (2022)
Sanne van der Rijt, Jaklien C Leemans, Sandrine Florquin, Riekelt H L Houtkooper, Alessandra Tammaro
Immunometabolic rewiring of tubular epithelial cells in kidney disease. Nature reviews. Nephrology 18 (9) (2022)
Marie-Françoise O'Donohue, Lydie M Da Costa, Marco Lezzerini, Sule Unal, Clément Joret, Marije Bartels, Eva Brilstra, Marijn Scheijde-Vermeulen, Ludivine Wacheul, Kim De Keersmaecker, Stijn Vereecke, Veerle Labarque, Manon Saby, Sophie D Lefevre, Jessica Platon, Nathalie Montel-Lehry, Nathalie Laugero, Eric Lacazette, Koen van Gassen, Riekelt H L Houtkooper, Pelin Ozlem Simsek-Kiper, Thierry Leblanc, Nese Yarali, Ömer Arda Çetinkaya, Nurten A Akarsu, Pierre-Emmanuel Gleizes, Denis L J Lafontaine, Alyson W MacInnes
HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia. Blood 139 (21) (2022)
Georges E Janssens, Lotte Grevendonk, Ruben Zapata Perez, Bauke V Schomakers, Johan de Vogel-van den Bosch, Jan M W Geurts, Michel van Weeghel, Patrick Schrauwen, Riekelt H L Houtkooper, Joris Hoeks
Healthy aging and muscle function are positively associated with NAD + abundance in humans. Nature aging 2 (3) (2022)
Deena Damschroder, Rubén Zapata-Pérez, Kristin Richardson, Frédéric M Vaz, Riekelt H L Houtkooper, Robert J Wessells
Stimulating the sir2-spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome. Disease models & mechanisms 15 (10) (2022)
Georges E Janssens, Lotte Grevendonk, Ruben Zapata Perez, Bauke V Schomakers, Johan de Vogel-van den Bosch, Jan M W Geurts, Michel van Weeghel, Patrick Schrauwen, Riekelt H L Houtkooper, Joris Hoeks
Healthy aging and muscle function are positively associated with NAD + abundance in humans. Nature aging 2 (3) (2022)
Georges E Janssens, Lotte Grevendonk, Ruben Zapata Perez, Bauke V Schomakers, Johan de Vogel-van den Bosch, Jan M W Geurts, Michel van Weeghel, Patrick Schrauwen, Riekelt H L Houtkooper, Joris Hoeks
Healthy aging and muscle function are positively associated with NAD + abundance in humans. Nature aging 2 (3) (2022)
Tineke A de Jong, Johanna F Semmelink, Simone W Denis, Janne W Bolt, Mario Maas, Marleen G H van de Sande, Riekelt H L Houtkooper, Lisa G M van Baarsen
Lower Metabolic Potential and Impaired Metabolic Flexibility in Human Lymph Node Stromal Cells from Patients with Rheumatoid Arthritis. Cells 12 (1) (2022)
Tineke A de Jong, Johanna F Semmelink, Simone W Denis, Janne W Bolt, Mario Maas, Marleen G H van de Sande, Riekelt H L Houtkooper, Lisa G M van Baarsen
Lower Metabolic Potential and Impaired Metabolic Flexibility in Human Lymph Node Stromal Cells from Patients with Rheumatoid Arthritis. Cells 12 (1) (2022)
Ivan Ramirez-Moral, Bianca L Ferreira, Joe M Butler, Michel van Weeghel, Natasja A Otto, Alex F de Vos, Xiao Yu, Menno D de Jong, Riekelt H L Houtkooper, Tom van der Poll
HIF-1α Stabilization in Flagellin-Stimulated Human Bronchial Cells Impairs Barrier Function. Cells 11 (3) (2022)
Rob C I Wüst, Bram F Coolen, Ntsiki M Held, Mariah R R Daal, Vida Alizadeh Tazehkandi, Luciënne Baks-Te Bulte, Marit Wiersma, Diederik W D Kuster, Bianca J J M Brundel, Michel van Weeghel, Gustav J Strijkers, Riekelt H L Houtkooper
The Antibiotic Doxycycline Impairs Cardiac Mitochondrial and Contractile Function. International journal of molecular sciences 22 (8) (2021)
Marte Molenaars, Bauke V Schomakers, Hyung L Elfrink, Arwen W Gao, Martin A T Vervaart, Mia L Pras-Raves, Angela C Luyf, Reuben L Smith, Mark G Sterken, Jan E Kammenga, Antoine H C van Kampen, Georges E Janssens, Frederic M Vaz, Michel van Weeghel, Riekelt H L Houtkooper
Metabolomics and lipidomics in Caenorhabditis elegans using a single-sample preparation. Disease models & mechanisms 14 (4) (2021)
Jamie I van der Vaart, Mariëtte R Boon, Riekelt H L Houtkooper
The Role of AMPK Signaling in Brown Adipose Tissue Activation. Cells 10 (5) (2021)
Ruben Zapata Perez, Ronald J A Wanders, Clara D M van Karnebeek, Riekelt H L Houtkooper
NAD+ homeostasis in human health and disease. EMBO molecular medicine 13 (7) (2021)
Carlijn M E Remie, Georges E Janssens, Lena Bilet, Michel van Weeghel, Bernard M F M Duvivier, Vera H W de Wit, Niels J Connell, Johanna A Jörgensen, Bauke V Schomakers, Vera B Schrauwen-Hinderling, Joris Hoeks, Matthijs K C Hesselink, Esther Phielix, Riekelt H L Houtkooper, Patrick Schrauwen
Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women. Diabetologia 64 (12) (2021)
Natasja A Otto, Joe M Butler, Ivan Ramirez, Michel van Weeghel, Jeroen W J van Heijst, Brendon P Scicluna, Riekelt H L Houtkooper, Alex F de Vos, Tom van der Poll
Adherence Affects Monocyte Innate Immune Function and Metabolic Reprogramming after Lipopolysaccharide Stimulation In Vitro. Journal of immunology (Baltimore, Md. : 1950) 206 (4) (2021)
Ruben Zapata Perez, Alessandra Tammaro, Bauke V Schomakers, Angelique M L Scantlebery, Simone Denis, Hyung L Elfrink, Judith Giroud-Gerbetant, Carles Cantó, Carmen López-Leonardo, Rebecca L McIntyre, Michel van Weeghel, Álvaro Sánchez-Ferrer, Riekelt H L Houtkooper
Reduced nicotinamide mononucleotide is a new and potent NAD+ precursor in mammalian cells and mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35 (4) (2021)
Frederic M Vaz, Henk van Lenthe, Martin A T Vervaart, Femke S Stet, Johanne H Klinkspoor, Hilary J Vernon, Susan M I Goorden, Riekelt H L Houtkooper, Willem Kulik, Ronald J A Wanders
An improved functional assay in blood spot to diagnose Barth syndrome using the monolysocardiolipin/cardiolipin ratio. Journal of inherited metabolic disease (2021)
Ronald J A Wanders, Gepke Visser, Sacha Ferdinandusse, Frederic M Vaz, Riekelt H L Houtkooper
Mitochondrial Fatty Acid Oxidation Disorders: Laboratory Diagnosis, Pathogenesis, and the Complicated Route to Treatment. Journal of lipid and atherosclerosis 9 (3) (2020)
Willianne Hoepel, Sona Allahverdiyeva, Haneen Harbiye, Steven W de Taeye, Alwin J van der Ham, Leonie de Boer, Sebastiaan A J Zaat, Michel van Weeghel, Dominique L P Baeten, Riekelt H L Houtkooper, Bart Everts, Gestur Vidarsson, Jeroen den Dunnen
IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming. Journal of immunology (Baltimore, Md. : 1950) 205 (12) (2020)
Yu Lei, Joanne A Hoogerland, Vincent W Bloks, Trijnie Bos, Aycha Bleeker, Henk Wolters, Justina Clarinda Wolters, Brenda S Hijmans, Theo H van Dijk, Rachel Thomas, Michel van Weeghel, Mithieux Gilles, Riekelt H L Houtkooper, Alain de Bruin, Fabienne Rajas, Folkert Kuipers, Maaike H Oosterveer
Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a. Hepatology (Baltimore, Md.) 72 (5) (2020)
Suzan J G Knottnerus, Isabella Mengarelli, Rob C I Wüst, Antonius Baartscheer, Jeannette C Bleeker, Ruben Coronel, Sacha Ferdinandusse, Kaomei Guan, Lodewijk IJlst, Wener Li, Xiaojing Luo, Vincent M Portero, Ying Ulbricht, Gepke Visser, Ronald J A Wanders, Frits A Wijburg, Arjan C Houweling, Riekelt H L Houtkooper, Connie R Bezzina
Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Can Be Improved by Lowering Accumulation of Fatty Acid Oxidation Intermediates. International journal of molecular sciences 21 (7) (2020)
Yasmine J Liu, Georges E Janssens, Rebecca L McIntyre, Marte Molenaars, Rashmi Kamble, Arwen W Gao, Aldo Jongejan, Michel van Weeghel, Alyson W MacInnes, Riekelt H L Houtkooper
Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion. PLoS genetics 15 (3) (2019)
Suzan J G Knottnerus, Jeannette C Bleeker, Rob C I Wüst, Sacha Ferdinandusse, Lodewijk IJlst, Frits A Wijburg, Ronald J A Wanders, Gepke Visser, Riekelt H L Houtkooper
Disorders of mitochondrial long-chain fatty acid oxidation and the carnitine shuttle. Reviews in endocrine & metabolic disorders 19 (1) (2019)
Rebecca L McIntyre, Eileen G Daniels, Marte Molenaars, Riekelt H L Houtkooper, Georges E Janssens
From molecular promise to preclinical results: HDAC inhibitors in the race for healthy aging drugs. EMBO molecular medicine 11 (9) (2019)
Ntsiki M Held, Eline N Kuipers, Michel van Weeghel, Jan Bert van Klinken, Simone W Denis, Marc Lombès, Ronald J Wanders, Frédéric M Vaz, Patrick C N Rensen, Arthur J Verhoeven, Mariëtte R Boon, Riekelt H L Houtkooper
Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation. Scientific reports 8 (1) (2018)
Arwen W Gao, Mark G Sterken, Jelmi Uit de Bos, Jelle van Creij, Rashmi Kamble, Basten L Snoek, Jan E Kammenga, Riekelt H L Houtkooper
Natural genetic variation in C. elegans identified genomic loci controlling metabolite levels. Genome research 28 (9) (2018)
Irene G M van Valkengoed, Carmen Argmann, Karen Ghauharali-van der Vlugt, Johannes M F G Aerts, Lizzy M Brewster, R J G Peters, Frédéric M Vaz, Riekelt H L Houtkooper
Ethnic differences in metabolite signatures and type 2 diabetes: a nested case-control analysis among people of South Asian, African and European origin. Nutrition & diabetes 7 (12) (2017)
Arwen W Gao, Iliana A Chatzispyrou, Rashmi Kamble, Yasmine J Liu, Katharina Herzog, Reuben L Smith, Henk van Lenthe, Martin A T Vervaart, Arno van Cruchten, Angela C Luyf, Antoine H C van Kampen, Mia L Pras-Raves, Frédéric M Vaz, Riekelt H L Houtkooper
A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegans. Scientific reports 7 (1) (2017)
Mandy Koopman, Helen Michels, Beverley M Dancy, Rashmi Kamble, Laurent Mouchiroud, Johan Auwerx, Ellen A A Nollen, Riekelt H L Houtkooper
A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans. Nature protocols 11 (10) (2016)