Dirk H Busch (Dirk Busch)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 77

Top Topics

Regulatory T Cells

Top Venues

Nature immunology

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Pascal Maximilian Winterhalter, Linda Warmuth, Philipp Hilgendorf, Julius M Schütz, Sarah Dötsch, Torsten Tonn, Luka Čičin Šain, Dirk H Busch, Kilian Schober
HLA reduction of human T cells facilitates generation of immunologically multicompatible cellular products. Blood advances 8 (13) (2024)
Pascal Maximilian Winterhalter, Linda Warmuth, Philipp Hilgendorf, Julius M Schuetz, Sarah Dötsch, Torsten Tonn, Luka Čičin Šain, Dirk H Busch, Kilian Schober
HLA reduction of human T cells facilitates generation of immunologically multi-compatible cellular products. Blood advances (2024)
Berit J Brinkmann, Alessia Floerchinger, Christina Schniederjohann, Tobias Roider, Mariana Coelho, Norman Mack, Peter-Martin Bruch, Nora Liebers, Sarah Dötsch, Dirk H Busch, Michael Schmitt, Frank Neumann, Philipp M Roessner, Martina Seiffert, Sascha Dietrich
CD20-bispecific antibodies improve response to CD19-CAR T-cells in lymphoma in-vitro and CLL in-vivo models. Blood (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Vanessa Mühlgrabner, Timo Peters, Rubí M-H Velasco Cárdenas, Benjamin Salzer, Janett Göhring, Angelika Plach, Maria Höhrhan, Iago Doel Perez, Vasco Dos Reis Gonçalves, Jesús Siller Farfán, Manfred Lehner, Hannes Stockinger, Wolfgang W A Schamel, Kilian Schober, Dirk H Busch, Michael Hudecek, Omer Dushek, Susana Minguet, René Platzer, Johannes B Huppa
TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation. Science advances 10 (36) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer (2024)
Vanessa Mühlgrabner, Timo Peters, Rubí M-H Velasco Cárdenas, Benjamin Salzer, Janett Göhring, Angelika Plach, Maria Höhrhan, Iago Doel Perez, Vasco Dos Reis Gonçalves, Jesús Siller Farfán, Manfred Lehner, Hannes Stockinger, Wolfgang W A Schamel, Kilian Schober, Dirk H Busch, Michael Hudecek, Omer Dushek, Susana Minguet, René Platzer, Johannes B Huppa
TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation. Science advances 10 (36) (2024)
Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature 629 (8011) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer 5 (1) (2024)
Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature 629 (8011) (2024)
Pascal Maximilian Winterhalter, Linda Warmuth, Philipp Hilgendorf, Julius M Schütz, Sarah Dötsch, Torsten Tonn, Luka Čičin Šain, Dirk H Busch, Kilian Schober
HLA reduction of human T cells facilitates generation of immunologically multicompatible cellular products. Blood advances 8 (13) (2024)
Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature 629 (8011) (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature (2024)
Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature (2024)
Berit J Brinkmann, Alessia Floerchinger, Christina Schniederjohann, Tobias Roider, Mariana Coelho, Norman Mack, Peter-Martin Bruch, Nora Liebers, Sarah Dötsch, Dirk H Busch, Michael Schmitt, Frank Neumann, Philipp M Roessner, Martina Seiffert, Sascha Dietrich
CD20-bispecific antibodies improve response to CD19-CAR T-cells in lymphoma in-vitro and CLL in-vivo models. Blood (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer 5 (1) (2024)
Pascal Maximilian Winterhalter, Linda Warmuth, Philipp Hilgendorf, Julius M Schütz, Sarah Dötsch, Torsten Tonn, Luka Čičin Šain, Dirk H Busch, Kilian Schober
HLA reduction of human T cells facilitates generation of immunologically multicompatible cellular products. Blood advances 8 (13) (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer 5 (1) (2024)
Berit J Brinkmann, Alessia Floerchinger, Christina Schniederjohann, Tobias Roider, Mariana Coelho, Norman Mack, Peter-Martin Bruch, Nora Liebers, Sarah Dötsch, Dirk H Busch, Michael Schmitt, Frank Neumann, Philipp M Roessner, Martina Seiffert, Sascha Dietrich
CD20-bispecific antibodies improve response to CD19-CAR T cells in lymphoma in vitro and CLL in vivo models. Blood 144 (7) (2024)
Sebastian B Lacher, Janina Dörr, Gustavo Pereira de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J Rudolph, Nadine Spranger, Matteo Morotti, Alizee J Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H Busch, Veit R Buchholz, Percy A Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan Philipp Böttcher
PGE 2 limits effector expansion of tumour-infiltrating stem-like CD8 + T cells. Nature 629 (8011) (2024)
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin-Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan Philipp Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R Buchholz, Sylvia Heink, Dirk H Busch, Ludger Klein, Thomas Korn
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4. Nature 627 (8003) (2024)
Sarah Dötsch, Mortimer Svec, Kilian Schober, Monika Hammel, Andreas Wanisch, Füsun Gökmen, Sebastian Jarosch, Linda Warmuth, Jack Barton, Luka Čičin Šain, Elvira D'Ippolito, Dirk H Busch
Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (10) (2023)
Sarah Dötsch, Mortimer Svec, Kilian Schober, Monika Hammel, Andreas Wanisch, Füsun Gökmen, Sebastian Jarosch, Linda Warmuth, Jack Barton, Luka Čičin Šain, Elvira D'Ippolito, Dirk H Busch
Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (10) (2023)
Sarah Dötsch, Mortimer Svec, Kilian Schober, Monika Hammel, Andreas Wanisch, Füsun Gökmen, Sebastian Jarosch, Linda Warmuth, Jack Barton, Luka Čičin Šain, Elvira D'Ippolito, Dirk H Busch
Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (10) (2023)
Sarah Dötsch, Mortimer Svec, Kilian Schober, Monika Hammel, Andreas Wanisch, Füsun Gökmen, Sebastian Jarosch, Linda Warmuth, Jack Barton, Luka Čičin Šain, Elvira D'Ippolito, Dirk H Busch
Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (10) (2023)
Sarah Dötsch, Mortimer Svec, Kilian Schober, Monika Hammel, Andreas Wanisch, Füsun Gökmen, Sebastian Jarosch, Linda Warmuth, Jack Barton, Luka Čičin Šain, Elvira D'Ippolito, Dirk H Busch
Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (10) (2023)
Simon P Fraessle, Claudia Tschulik, Manuel Effenberger, Vlad Cletiu, Maria Gerget, Kilian Schober, Dirk H Busch, Lothar Germeroth, Christian Stemberger, Mateusz P Poltorak
Activation-inducible CAR expression enables precise control over engineered CAR T cell function. Communications biology 6 (1) (2023)
Kan Xie, Helmut Fuchs, Enzo Scifo, Dan Liu, Nasir Ahmad Aziz, Juan Antonio Aguilar-Pimentel, Oana Veronica Amarie, Lore Becker, Patricia da Silva-Buttkus, Julia Calzada-Wack, Yi-Li Cho, Yushuang Deng, A Cole Edwards, Lillian Garrett, Christina Georgopoulou, Raffaele Gerlini, Sabine Maria Hölter, Tanja Klein-Rodewald, Michael Kramer, Stefanie Leuchtenberger, Dimitra Lountzi, Phillip Mayer-Kuckuk, Lena L Nover, Manuela A Oestereicher, Clemens Overkott, Brandon L Pearson, Birgit Rathkolb, Jan Rozman, Jenny Russ, Kristina Schaaf, Nadine Spielmann, Adrián Sanz-Moreno, Claudia Stoeger, Irina Treise, Daniele Bano, Dirk H Busch, Jochen Graw, Martin Klingenspor, Florentine Radelfahr, Beverly A Mock, Paolo Salomoni, Carsten B Schmidt-Weber, Marco Weiergräber, Eckhard Wolf, Wolfgang Wurst, Valérie Gailus-Durner, Monique M B Breteler, Martin Hrabě de Angelis, Dan Ehninger
Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice. Nature communications 13 (1) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology (2022)
Laura M Mateyka, Philipp M Strobl, Sebastian Jarosch, Sebastian J C Scheu, Dirk H Busch, Elvira D'Ippolito
Gene Signatures of T-Cell Activation Can Serve as Predictors of Functionality for SARS-CoV-2-Specific T-Cell Receptors. Vaccines 10 (10) (2022)
Marten Plambeck, Atefeh Kazeroonian, Dirk Loeffler, Lorenz Kretschmer, Ciro Salinno, Timm Schroeder, Dirk H Busch, Michael Flossdorf, Veit R Buchholz
Heritable changes in division speed accompany the diversification of single T cell fate. Proceedings of the National Academy of Sciences of the United States of America 119 (9) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Simone Weber, Victoria Kehl, Johanna Erber, Karolin I Wagner, Ana-Marija Jetzlsperger, Teresa Burrell, Kilian Schober, Philipp Schommers, Max Augustin, Claudia S Crowell, Markus Gerhard, Christof Winter, Andreas Moosmann, Christoph D Spinner, Ulrike Protzer, Dieter Hoffmann, Elvira D'Ippolito, Dirk H Busch
CMV seropositivity is a potential novel risk factor for severe COVID-19 in non-geriatric patients. PloS one 17 (5) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Anna Purcarea, Sebastian Jarosch, Jack Barton, Simon Grassmann, Ludwig Pachmayr, Elvira D'Ippolito, Monika Hammel, Anna Hochholzer, Karolin I Wagner, Joost H van den Berg, Veit R Buchholz, John B A G Haanen, Dirk H Busch, Kilian Schober
Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidity. Science immunology 7 (74) (2022)
Sophia E Schambeck, Laura M Mateyka, Teresa Burrell, Natalia Graf, Ioana Brill, Thomas Stark, Ulrike Protzer, Dirk H Busch, Markus Gerhard, Henriette Riehl, Holger Poppert
Two-Year Follow-Up on Chemosensory Dysfunction and Adaptive Immune Response after Infection with SARS-CoV-2 in a Cohort of 44 Healthcare Workers. Life (Basel, Switzerland) 12 (10) (2022)
Eva Bräunlein, Gaia Lupoli, Franziska Füchsl, Esam T Abualrous, Niklas de Andrade Krätzig, Dario Gosmann, Lukas Wietbrock, Sebastian Lange, Thomas Engleitner, Huan Lan, Stefan Audehm, Manuel Effenberger, Melanie Boxberg, Katja Steiger, Yinshui Chang, Kai Yu, Cigdem Atay, Florian Bassermann, Wilko Weichert, Dirk H Busch, Roland Rad, Christian Freund, Iris Antes, Angela M Krackhardt
Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma. Journal for immunotherapy of cancer 9 (9) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Philipp Lückemeier, Katherine L Molter, Sebastian Jarosch, Patrick Huppertz, Anna Purcarea, Manuel J P Effenberger, Magdalena Nauerth, Elvira D'Ippolito, Kilian Schober, Dirk H Busch
Global k off -rates of polyclonal T-cell populations merge subclonal avidities and predict functionality. European journal of immunology 52 (4) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Busheng Xue, Kristina von Heyking, Hendrik Gassmann, Mansour Poorebrahim, Melanie Thiede, Kilian Schober, Josef Mautner, Julia Hauer, Jürgen Ruland, Dirk H Busch, Uwe Thiel, Stefan E G Burdach
T Cells Directed against the Metastatic Driver Chondromodulin-1 in Ewing Sarcoma: Comparative Engineering with CRISPR/Cas9 vs. Retroviral Gene Transfer for Adoptive Transfer. Cancers 14 (22) (2022)
Lillian Garrett, Patricia da Silva-Buttkus, Birgit Rathkolb, Raffaele Gerlini, Lore Becker, Adrian Sanz-Moreno, Claudia Seisenberger, Annemarie Zimprich, Antonio Aguilar-Pimentel, Oana Veronica Amarie, Yi-Li Cho, Markus Kraiger, Nadine Spielmann, Julia Calzada-Wack, Susan Marschall, Dirk H Busch, Carsten Schmitt-Weber, Eckhard Wolf, Wolfgang Wurst, Helmut Fuchs, Valérie Gailus-Durner, Sabine Maria Hölter, Martin Hrabě de Angelis
Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk. Disease models & mechanisms 15 (3) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
David S Fischer, Meshal Ansari, Karolin I Wagner, Sebastian Jarosch, Yiqi Huang, Christoph H Mayr, Maximilian Strunz, Niklas J Lang, Elvira D'Ippolito, Monika Hammel, Laura Mateyka, Simone Weber, Lisa S Wolff, Klaus Witter, Isis E Fernandez, Gabriela Leuschner, Katrin Milger, Marion Frankenberger, Lorenz Nowak, Katharina Heinig-Menhard, Ina Koch, Mircea G Stoleriu, Anne Hilgendorff, Jürgen Behr, Andreas Pichlmair, Benjamin Schubert, Fabian Joachim Theis, Dirk H Busch, Herbert B Schiller, Kilian Schober
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'. Nature communications 12 (1) (2021)
Michael Hiltensperger, Eduardo Beltrán, Ravi Kant, Sofia Tyystjärvi, Gildas Lepennetier, Helena Domínguez Moreno, Isabel J Bauer, Simon Grassmann, Sebastian Jarosch, Kilian Schober, Veit R Buchholz, Selin Kenet, Christiane Gasperi, Rupert Öllinger, Roland Rad, Andreas Muschaweckh, Christopher Sie, Lilian Aly, Benjamin Knier, Garima Garg, Ali M Afzali, Lisa Ann Gerdes, Tania Kümpfel, Soeren Franzenburg, Naoto Kawakami, Bernhard Hemmer, Dirk H Busch, Thomas Misgeld, Klaus Dornmair, Thomas Korn
Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity. Nature immunology 22 (7) (2021)
Sophia E Schambeck, Claudia S Crowell, Karolin I Wagner, Elvira D'Ippolito, Teresa Burrell, Hrvoje Mijočević, Ulrike Protzer, Dirk H Busch, Markus Gerhard, Holger Poppert, Henriette Beyer
Phantosmia, Parosmia, and Dysgeusia Are Prolonged and Late-Onset Symptoms of COVID-19. Journal of clinical medicine 10 (22) (2021)
Franziska Blaeschke, Dana Stenger, Antonia Apfelbeck, Bruno L Cadilha, Mohamed-Reda Benmebarek, Jasmin Mahdawi, Eva Ortner, Mareike Lepenies, Nicola Habjan, Felicitas Rataj, Semjon Willier, Theresa Kaeuferle, Robbie G Majzner, Dirk H Busch, Sebastian Kobold, Tobias Feuchtinger
Augmenting anti-CD19 and anti-CD22 CAR T-cell function using PD-1-CD28 checkpoint fusion proteins. Blood cancer journal 11 (6) (2021)
Kilian Schober, Thomas R Müller, Dirk H Busch
Orthotopic T-Cell Receptor Replacement-An "Enabler" for TCR-Based Therapies. Cells 9 (6) (2020)
Thomas R Müller, Corinna Schuler, Monika Hammel, Amelie Köhler, Sabrina Jutz, Judith Leitner, Kilian Schober, Dirk H Busch, Peter Steinberger
A T-cell reporter platform for high-throughput and reliable investigation of TCR function and biology. Clinical & translational immunology 9 (11) (2020)
Simon Grassmann, Lorenz Leopold Mihatsch, Jonas Mir, Atefeh Kazeroonian, Roza Rahimi, Sophie Flommersfeld, Kilian Schober, Inge Hensel, Justin Leube, Ludwig O Pachmayr, Lorenz Kretschmer, Qin Zhang, Adrien Jolly, M Zeeshan Chaudhry, Matthias Schiemann, Luka Cicin-Sain, Thomas Höfer, Dirk H Busch, Michael Flossdorf, Veit R Buchholz
Early emergence of T central memory precursors programs clonal dominance during chronic viral infection. Nature immunology 21 (12) (2020)
Kilian Schober, Florian Voit, Simon Grassmann, Thomas R Müller, Joel Eggert, Sebastian Jarosch, Bianca Weißbrich, Patrick Hoffmann, Lisa Borkner, Enzo Nio, Lorenzo Fanchi, Christopher R Clouser, Aditya Radhakrishnan, Lorenz Mihatsch, Philipp Lückemeier, Justin Leube, Georg Dössinger, Ludger Klein, Michael Neuenhahn, Jennifer D Oduro, Luka Cicin-Sain, Veit R Buchholz, Dirk H Busch
Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection. Nature immunology 21 (4) (2020)
Lorenz Kretschmer, Michael Flossdorf, Jonas Mir, Yi-Li Cho, Marten Plambeck, Irina Treise, Albulena Toska, Susanne Heinzel, Matthias Schiemann, Dirk H Busch, Veit R Buchholz
Differential expansion of T central memory precursor and effector subsets is regulated by division speed. Nature communications 11 (1) (2020)
Kilian Schober, Pim Fuchs, Jonas Mir, Monika Hammel, Lorenzo Fanchi, Michael Flossdorf, Dirk H Busch
The CMV-Specific CD8+ T Cell Response Is Dominated by Supra-Public Clonotypes with High Generation Probabilities. Pathogens (Basel, Switzerland) 9 (8) (2020)
Elvira D'Ippolito, Karolin I Wagner, Dirk H Busch
Needle in a Haystack: The Naïve Repertoire as a Source of T Cell Receptors for Adoptive Therapy with Engineered T Cells. International journal of molecular sciences 21 (21) (2020)
Sebastian Johannes Schober, Melanie Thiede, Hendrik Gassmann, Carolin Prexler, Busheng Xue, David Schirmer, Dirk Wohlleber, Stefanie Stein, Thomas G P Grünewald, Dirk H Busch, Guenther H S Richter, Stefan E G Burdach, Uwe Thiel
MHC Class I-Restricted TCR-Transgenic CD4+ T Cells Against STEAP1 Mediate Local Tumor Control of Ewing Sarcoma In Vivo. Cells 9 (7) (2020)
Immanuel Andrä, Hanna Ulrich, Susi Dürr, Dominik Soll, Lynette Henkel, Corinne Angerpointner, Julia Ritter, Sabine Przibilla, Herbert Stadler, Manuel Effenberger, Dirk H Busch, Matthias Schiemann
An Evaluation of T-Cell Functionality After Flow Cytometry Sorting Revealed p38 MAPK Activation. Cytometry. Part A : the journal of the International Society for Analytical Cytology 97 (2) (2020)
Juan Antonio Aguilar-Pimentel, Yi-Li Cho, Raffaele Gerlini, Julia Calzada-Wack, Maria Wimmer, Philipp Mayer-Kuckuk, Thure Adler, Carsten B Schmidt-Weber, Dirk H Busch, Helmut Fuchs, Valérie Gailus-Durner, Markus Ollert, Martin Hrabě de Angelis, Claes Ohlsson, Matti Poutanen, Raffaele Teperino, Leena Strauss
Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice. Scientific reports 10 (1) (2020)
Manuel Effenberger, Andreas Stengl, Kilian Schober, Maria Gerget, Maximilian Kampick, Thomas R Müller, Dominik Schumacher, Jonas Helma, Heinrich Leonhardt, Dirk H Busch
FLEXamers: A Double Tag for Universal Generation of Versatile Peptide-MHC Multimers. Journal of immunology (Baltimore, Md. : 1950) 202 (7) (2019)
Kilian Schober, Thomas R Müller, Füsun Gökmen, Simon Grassmann, Manuel Effenberger, Mateusz Poltorak, Christian Stemberger, Kathrin Schumann, Theodore L Roth, Alexander Marson, Dirk H Busch
Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function. Nature biomedical engineering 3 (12) (2019)
Kilian Schober, Veit R Buchholz, Dirk H Busch
TCR repertoire evolution during maintenance of CMV-specific T-cell populations. Immunological reviews 283 (1) (2019)
Tobias Hassler, Emanuel Urmann, Sebastian Teschner, Christine Federle, Thamotharampillai Dileepan, Kilian Schober, Marc K Jenkins, Dirk H Busch, Maria Hinterberger, Ludger Klein
Inventories of naive and tolerant mouse CD4 T cell repertoires reveal a hierarchy of deleted and diverted T cell receptors. Proceedings of the National Academy of Sciences of the United States of America 116 (37) (2019)
Matthias Mulazzani, Simon P Fräßle, Iven von Mücke-Heim, Sigrid Langer, Xiaolan Zhou, Hellen Ishikawa-Ankerhold, Justin Leube, Wenlong Zhang, Sarah Dötsch, Mortimer Svec, Martina Rudelius, Martin Dreyling, Michael von Bergwelt-Baildon, Andreas Straube, Veit R Buchholz, Dirk H Busch, Louisa von Baumgarten
Long-term in vivo microscopy of CAR T cell dynamics during eradication of CNS lymphoma in mice. Proceedings of the National Academy of Sciences of the United States of America 116 (48) (2019)
Michaela C Baldauf, Julia S Gerke, Andreas Kirschner, Franziska Blaeschke, Manuel Effenberger, Kilian Schober, Rebeca Alba Rubio, Takayuki Kanaseki, Merve Meryem Kıran, Marlene Dallmayer, Julian Musa, Nurset Akpolat, Ayse Nur Akatlı, Fernando Colonna Rosman, Ozlem Isiksacan Ozen, Shintaro Sugita, Tadashi Hasegawa, Haruhiko Sugimura, Daniel Baumhoer, Maximilian Martin Ludwig Knott, Giuseppina Sannino, Aruna Marchetto, Jing Li, Dirk H Busch, Tobias Feuchtinger, Shunya Ohmura, Martin F Orth, Uwe Thiel, Thomas Kirchner, Thomas G P Grünewald
Systematic identification of cancer-specific MHC-binding peptides with RAVEN. Oncoimmunology 7 (9) (2018)
Irina Treise, Eva M Huber, Tanja Klein-Rodewald, Wolfgang Heinemeyer, Simon A Grassmann, Michael Basler, Thure Adler, Birgit Rathkolb, Laura Helming, Christian Andres, Matthias Klaften, Christina Landbrecht, Thomas Wieland, Tim M Strom, Kathy D McCoy, Andrew J Macpherson, Eckhard Wolf, Marcus Groettrup, Markus Ollert, Frauke Neff, Valerie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis, Michael Groll, Dirk H Busch
Defective immuno- and thymoproteasome assembly causes severe immunodeficiency. Scientific reports 8 (1) (2018)
Fabian Mohr, Sabine Przibilla, Franziska Leonhardt, Christian Stemberger, Stefan Dreher, Thomas R Müller, Simon P Fräßle, Georg P Schmidt, Marie-Luise Kiene, Herbert Stadler, Dirk H Busch
Efficient immunoaffinity chromatography of lymphocytes directly from whole blood. Scientific reports 8 (1) (2018)
Tihana Tršan, Kristina Vuković, Petra Filipović, Ana Lesac Brizić, Niels A W Lemmermann, Kilian Schober, Dirk H Busch, William J Britt, Martin Messerle, Astrid Krmpotić, Stipan Jonjić
Cytomegalovirus vector expressing RAE-1γ induces enhanced anti-tumor capacity of murine CD8+ T cells. European journal of immunology 47 (8) (2017)
Helmut Fuchs, Sibylle Sabrautzki, Gerhard K H Przemeck, Bettina Lorenz-Depiereux, Lore Becker, Birgit Rathkolb, Marion Horsch, Lillian Garrett, Manuela A Östereicher, Wolfgang Hans, Koichiro Abe, Nobuho Sagawa, Jan Rozman, Ingrid L Vargas-Panesso, Michael Sandholzer, Thomas S Lisse, Thure Adler, Juan Antonio Aguilar-Pimentel, Julia Calzada-Wack, Nicole Ehrhard, Ralf Elvert, Christine Gau, Sabine Maria Hölter, Katja Micklich, Kristin Moreth, Cornelia Prehn, Oliver Puk, Ildiko Racz, Claudia Stoeger, Alexandra Vernaleken, Dian Michel, Susanne Diener, Thomas Wieland, Jerzy Adamski, Raffi Bekeredjian, Dirk H Busch, John Favor, Jochen Graw, Martin Klingenspor, Christoph Lengger, Holger Maier, Frauke Neff, Markus Ollert, Tobias Stoeger, Ali Oender Yildirim, Tim M Strom, Andreas Zimmer, Eckhard Wolf, Wolfgang Wurst, Florentine Radelfahr, Johannes Beckers, Valerie Gailus-Durner, Martin Hrabě de Angelis
The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations. G3 (Bethesda, Md.) 6 (12) (2016)
Ana Textor, Karin Schmidt, Peter-M Kloetzel, Bianca Weißbrich, Cynthia Perez, Jehad Charo, Kathleen Anders, John Sidney, Alessandro Sette, Ton N M Schumacher, Christin Keller, Dirk H Busch, Ulrike Seifert, Thomas Blankenstein
Preventing tumor escape by targeting a post-proteasomal trimming independent epitope. The Journal of experimental medicine 213 (11) (2016)