Edward M Schaeffer (Edward Schaeffer)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 22

Top Topics

Radical Prostatectomy

High Throughput Sequencing

Dna Damage Response

Top Venues

Nature communications

Molecular cancer research : MCR

Prostate cancer and prostatic diseases

Research square

This page only lists publications with an associated author ORCID identifier.

Publications

Sukanya Panja, Mihai Ioan Truica, Christina Y Yu, Vamshi Saggurthi, Michael W Craige, Katie Whitehead, Mayra V Tuiche, Aymen Al-Saadi, Riddhi Vyas, Shridar Ganesan, Suril Gohel, Frederick Coffman, James Scott Parrott, Songhua Quan, Shantenu Jha, Isaac Kim, Edward M Schaeffer, Vishal Kothari, Sarki A Abdulkadir, Antonina Mitrofanova
Mechanism-centric regulatory network identifies NME2 and MYC programs as markers of Enzalutamide resistance in CRPC. Nature communications 15 (1) (2024)
Sukanya Panja, Mihai Ioan Truica, Christina Y Yu, Vamshi Saggurthi, Michael W Craige, Katie Whitehead, Mayra V Tuiche, Aymen Al-Saadi, Riddhi Vyas, Shridar Ganesan, Suril Gohel, Frederick Coffman, James Scott Parrott, Songhua Quan, Shantenu Jha, Isaac Kim, Edward M Schaeffer, Vishal Kothari, Sarki A Abdulkadir, Antonina Mitrofanova
Mechanism-centric regulatory network identifies NME2 and MYC programs as markers of Enzalutamide resistance in CRPC. Nature communications 15 (1) (2024)
Mohamed N Omar, Zhuoran Xu, Sophie B Rand, Mohammad K Alexanderani, Daniela C Salles, Itzel Valencia, Edward M Schaeffer, Brian D Robinson, Tamara L Lotan, Massimo Loda, Luigi Marchionni
Semi-Supervised, Attention-Based Deep Learning for Predicting TMPRSS2:ERG Fusion Status in Prostate Cancer Using Whole Slide Images. Molecular cancer research : MCR 22 (4) (2024)
Eric V Li, Anna M Busza, Mohammad R Siddiqui, Jonathan A Aguiar, Mary-Kate Keeter, Clayton Neill, Sai K S R Kumar, Xinlei Mi, Edward M Schaeffer, Hiten D Patel, Ashley Evan Ross
Detection of clinically significant prostate cancer following initial omission of biopsy in multiparametric MRI era. Prostate cancer and prostatic diseases (2024)
Sukanya Panja, Mihai Ioan Truica, Christina Y Yu, Vamshi Saggurthi, Michael W Craige, Katie Whitehead, Mayra V Tuiche, Aymen Al-Saadi, Riddhi Vyas, Shridar Ganesan, Suril Gohel, Frederick Coffman, James Scott Parrott, Songhua Quan, Shantenu Jha, Isaac Kim, Edward M Schaeffer, Vishal Kothari, Sarki A Abdulkadir, Antonina Mitrofanova
Mechanism-centric regulatory network identifies NME2 and MYC programs as markers of Enzalutamide resistance in CRPC. Nature communications 15 (1) (2024)
Sukanya Panja, Mihai Ioan Truica, Christina Y Yu, Vamshi Saggurthi, Michael W Craige, Katie Whitehead, Mayra V Tuiche, Aymen Al-Saadi, Riddhi Vyas, Shridar Ganesan, Suril Gohel, Frederick Coffman, James Scott Parrott, Songhua Quan, Shantenu Jha, Isaac Kim, Edward M Schaeffer, Vishal Kothari, Sarki A Abdulkadir, Antonina Mitrofanova
Mechanism-centric regulatory network identifies NME2 and MYC programs as markers of Enzalutamide resistance in CRPC. Nature communications 15 (1) (2024)
Mohamed N Omar, Zhuoran Xu, Sophie B Rand, Mohammad K Alexanderani, Daniela C Salles, Itzel Valencia, Edward M Schaeffer, Brian D Robinson, Tamara L Lotan, Massimo Loda, Luigi Marchionni
Semi-Supervised, Attention-Based Deep Learning for Predicting TMPRSS2:ERG Fusion Status in Prostate Cancer Using Whole Slide Images. Molecular cancer research : MCR (2024)
Mohamed N Omar, Zhuoran Xu, Sophie B Rand, Mohammad K Alexanderani, Daniela C Salles, Itzel Valencia, Edward M Schaeffer, Brian D Robinson, Tamara L Lotan, Massimo Loda, Luigi Marchionni
Semi-Supervised, Attention-Based Deep Learning for Predicting TMPRSS2:ERG Fusion Status in Prostate Cancer Using Whole Slide Images. Molecular cancer research : MCR 22 (4) (2024)
Sukanya Panja, Mihai Ioan Truica, Christina Y Yu, Vamshi Saggurthi, Michael W Craige, Katie Whitehead, Mayra V Tuiche, Aymen Al-Saadi, Riddhi Vyas, Shridar Ganesan, Suril Gohel, Frederick Coffman, James Scott Parrott, Songhua Quan, Shantenu Jha, Isaac Kim, Edward M Schaeffer, Vishal Kothari, Sarki A Abdulkadir, Antonina Mitrofanova
Mechanism-centric regulatory network identifies NME2 and MYC programs as markers of Enzalutamide resistance in CRPC. Nature communications 15 (1) (2024)
Mohamed N Omar, Zhuoran Xu, Sophie B Rand, Mohammad K Alexanderani, Daniela C Salles, Itzel Valencia, Edward M Schaeffer, Brian D Robinson, Tamara L Lotan, Massimo Loda, Luigi Marchionni
Semi-Supervised, Attention-Based Deep Learning for Predicting TMPRSS2:ERG Fusion Status in Prostate Cancer Using Whole Slide Images. Molecular cancer research : MCR 22 (4) (2024)
Mohamed N Omar, Zhuoran Xu, Sophie B Rand, Mohammad K Alexanderani, Daniela C Salles, Itzel Valencia, Edward M Schaeffer, Brian D Robinson, Tamara L Lotan, Massimo Loda, Luigi Marchionni
Semi-Supervised, Attention-Based Deep Learning for Predicting TMPRSS2:ERG Fusion Status in Prostate Cancer Using Whole Slide Images. Molecular cancer research : MCR 22 (4) (2024)
Mohamed N Omar, Zhuoran Xu, Sophie B Rand, Mohammad K Alexanderani, Daniela C Salles, Itzel Valencia, Edward M Schaeffer, Brian D Robinson, Tamara L Lotan, Massimo Loda, Luigi Marchionni
Semi-Supervised, Attention-Based Deep Learning for Predicting TMPRSS2:ERG Fusion Status in Prostate Cancer Using Whole Slide Images. Molecular cancer research : MCR (2024)
Gerhardt Attard, Marina Parry, Emily Grist, Larissa Mendes, Peter Dutey-Magni, Ashwin Sachdeva, Christopher Brawley, Laura Murphy, James Proudfoot, Sharanpreet Lall, Yang Liu, Stefanie Friedrich, Mazlina Ismail, Alex Hoyle, Adnan Ali, Aine Haran, Anna Wingate, Leila Zakka, Daniel Wetterskog, Claire Amos, Nafisah Atako, Victoria Wang, Hannah Rush, Robert Jones, Hing Y Leung, William Cross, Silke Gillessen Sommer, Chris Parker, Simon Chowdhury, Tamara L Lotan, Teresa Marafioti, Alfonso Urbanucci, Edward M Schaeffer, Daniel Spratt, David Waugh, Thomas Powles, Daniel Berney, Matthew Robert Sydes, Mahesh Parmar, Anis Hamid, Felix Y Feng, Christopher Sweeney, Elai Davicioni, Noel Clarke, Nicholas James, Louise Brown
Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of the STAMPEDE abiraterone Phase 3 trial. Research square (2023)
Mohammad R Siddiqui, Eric V Li, Sai K S R Kumar, Anna Busza, Jasmine S Lin, Ashorne K Mahenthiran, Jonathan A Aguiar, Parth V Shah, Brandon Ansbro, Jordan M Rich, Soliman A S Moataz, Mary-Kate Keeter, Quan Mai, Xinlei Mi, Jeffrey J Tosoian, Edward M Schaeffer, Hiten D Patel, Ashley Evan Ross
Optimizing detection of clinically significant prostate cancer through nomograms incorporating mri, clinical features, and advanced serum biomarkers in biopsy naïve men. Prostate cancer and prostatic diseases (2023)
Gerhardt Attard, Marina Parry, Emily Grist, Larissa Mendes, Peter Dutey-Magni, Ashwin Sachdeva, Christopher Brawley, Laura Murphy, James Proudfoot, Sharanpreet Lall, Yang Liu, Stefanie Friedrich, Mazlina Ismail, Alex Hoyle, Adnan Ali, Aine Haran, Anna Wingate, Leila Zakka, Daniel Wetterskog, Claire Amos, Nafisah Atako, Victoria Wang, Hannah Rush, Robert Jones, Hing Y Leung, William Cross, Silke Gillessen Sommer, Chris Parker, Simon Chowdhury, Tamara L Lotan, Teresa Marafioti, Alfonso Urbanucci, Edward M Schaeffer, Daniel Spratt, David Waugh, Thomas Powles, Daniel Berney, Matthew Robert Sydes, Mahesh Parmar, Anis Hamid, Felix Y Feng, Christopher Sweeney, Elai Davicioni, Noel Clarke, Nicholas James, Louise Brown
Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of the STAMPEDE abiraterone Phase 3 trial. Research square (2023)
Xintao Qiu, Nadia Boufaied, Tarek Hallal, Avery Feit, Anna de Polo, Adrienne M Luoma, Walaa Alahmadi, Janie Larocque, Giorgia Zadra, Yingtian Xie, Shengqing Gu, Qin Tang, Yi Zhang, Sudeepa Syamala, Ji-Heui Seo, Connor Bell, Edward O'Connor, Yang Liu, Edward M Schaeffer, R Jeffrey Karnes, Sheila Weinmann, Elai Davicioni, Colm Morrissey, Paloma Cejas, Leigh Ellis, Massimo Loda, Kai W Wucherpfennig, Mark M Pomerantz, Daniel E Spratt, Eva Corey, Matthew L Freedman, X Shirley Liu, Myles A Brown, Henry W Long, David P Labbé
MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets. Nature communications 13 (1) (2022)
Adam B Weiner, Christina Y Yu, Mitali Kini, Yang Liu, Elai Davicioni, Antonina Mitrofanova, Tamara L Lotan, Edward M Schaeffer
High intratumoral plasma cells content in primary prostate cancer defines a subset of tumors with potential susceptibility to immune-based treatments. Prostate cancer and prostatic diseases (2022)
Mohammad R Siddiqui, Brandon Ansbro, Parth V Shah, Jonathan A Aguiar, Eric V Li, Jordan M Rich, Ashorne K Mahenthiran, Soliman A S Moataz, Mary-Kate Keeter, Quan Mai, Xinlei Mi, Edward M Schaeffer, Ashley Evan Ross
Real-world use of MRI for risk stratification prior to prostate biopsy. Prostate cancer and prostatic diseases (2022)
Adam B Weiner, Thiago Vidotto, Yang Liu, Adrianna A Mendes, Daniela C Salles, Farzana A Faisal, Sanjana Murali, Matthew R McFarlane, Eddie L Imada, Xin Zhao, Ziwen Li, Elai Davicioni, Luigi Marchionni, Sunita Shankar, Stephen J Freedland, Daniel E Spratt, Jennifer D Wu, Tamara L Lotan, Edward M Schaeffer
Plasma cells are enriched in localized prostate cancer in Black men and are associated with improved outcomes. Nature communications 12 (1) (2021)
Adam B Weiner, Yang Liu, Matthew McFarlane, Pushpinder Singh Bawa, Eric V Li, Xin Zhao, Ziwen Li, Tanya Hammoud, Munna Hazime, R Jeffrey Karnes, Elai Davicioni, Zachery R Reichert, Arul M Chinnaiyan, Tamara L Lotan, Daniel E Spratt, Edward M Schaeffer
A transcriptomic model for homologous recombination deficiency in prostate cancer. Prostate cancer and prostatic diseases (2021)
Yang Yi, Yanqiang Li, Qingshu Meng, Qiaqia Li, Fuxi Li, Bing Lu, Jiangchuan Shen, Ladan Fazli, Dongyu Zhao, Chao Li, Weihua Jiang, Rui Wang, Qipeng Liu, Aileen Szczepanski, Qianru Li, Wei Qin, Adam B Weiner, Tamara L Lotan, Zhe Ji, Sundeep Kalantry, Lu Wang, Edward M Schaeffer, Hengyao Niu, Xuesen Dong, Wei Zhao, Kaifu Chen, Qi Cao
A PRC2-independent function for EZH2 in regulating rRNA 2'-O methylation and IRES-dependent translation. Nature cell biology 23 (4) (2021)
Walter Rayford, Alp Tuna Beksac, Jordan Alger, Mohammed Alshalalfa, Mohsen Ahmed, Irtaza Khan, Ugo Giovanni Falagario, Yang Liu, Elai Davicioni, Daniel E Spratt, Edward M Schaeffer, Felix Y Feng, Brandon Mahal, Paul L Nguyen, Robert B Den, Mark D Greenberger, Randy Bradley, Justin M Watson, Matthew Beamer, Lambros Stamatakis, Darrell J Carmen, Shivanshu Awasthi, Jonathan Hwang, Rachel Weil, Harri Merisaari, Nihal Mohamed, Leslie A Deane, Dimple Chakravarty, Kamlesh K Yadav, Kosj Yamoah, Sujit S Nair, Ashutosh K Tewari
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences. Communications biology 4 (1) (2021)