Marcus Bantscheff

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 45

Top Topics

Acute Myeloid Leukemia

Binding Protein

Top Venues

Nature communications

Molecular systems biology

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Joseph E Pero, Elizabeth A Mueller, Ashley M Adams, Ramona S Adolph, Parikshit Bagchi, Dale Balce, Marcus Bantscheff, Ona Barauskas, Istvan Bartha, Dana Bohan, Haiying Cai, Esteban Carabajal, James Cassidy, Matthew Cato, Khuram W Chaudhary, Dingjun Chen, Yi-Pei Chen, Christophe Colas, Isra Darwech, H Christian Eberl, Beth Fernandez, Earl Gordon, Johannes Grosse, Justin Hansen, Belinda E Hetzler, Seungmin Hwang, Sam Jeyasingh, Beatriz Kowalski, Stephanie Lehmann, Gary Lo, Michael McAllaster, Charles McHugh, Corey Momont, Zachary Newby, Maria Nigro, Fatai Oladunni, Malar Pannirselvam, Arnold Park, Neil Pearson, Andrew J Peat, Bob Plastridge, Rohit Ranjan, Pegah Safabakhsh, Nathan D Shapiro, Leah Soriaga, Neil Stokes, David Sweeney, Lindsey Talecki, Amalio Telenti, Ashley Terrell, Winston Tse, Lisha Wang, Shuya Wang, Laura Wedel, Thilo Werner, Deidre Dalmas Wilk, Samantha Yim, Jiayi Zhou
Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety. Journal of medicinal chemistry 67 (16) (2024)
Mira L Burtscher, Stephan Gade, Martín Garrido-Rodriguez, Anna Rutkowska, Thilo Werner, H Christian Eberl, Massimo Petretich, Natascha Knopf, Katharina Zirngibl, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff, Maria Fälth-Savitski, Julio Saez-Rodriguez
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition. Molecular systems biology 20 (4) (2024)
Mira L Burtscher, Stephan Gade, Martín Garrido-Rodriguez, Anna Rutkowska, Thilo Werner, H Christian Eberl, Massimo Petretich, Natascha Knopf, Katharina Zirngibl, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff, Maria Fälth-Savitski, Julio Saez-Rodriguez
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition. Molecular systems biology (2024)
Mira L Burtscher, Stephan Gade, Martín Garrido-Rodriguez, Anna Rutkowska, Thilo Werner, H Christian Eberl, Massimo Petretich, Natascha Knopf, Katharina Zirngibl, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff, Maria Fälth-Savitski, Julio Saez-Rodriguez
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition. Molecular systems biology (2024)
Mira L Burtscher, Stephan Gade, Martín Garrido-Rodriguez, Anna Rutkowska, Thilo Werner, H Christian Eberl, Massimo Petretich, Natascha Knopf, Katharina Zirngibl, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff, Maria Fälth-Savitski, Julio Saez-Rodriguez
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition. Molecular systems biology 20 (4) (2024)
Anna Rutkowska-Klute, H Christian Eberl, Thilo Werner, Marco L Hennrich, Daniel C Sevin, Massimo Petretich, James P Reddington, Shirin Pocha, Stephan Gade, Amalia Martinez-Segura, Dmytro Dvornikov, Joel Karpiak, Gavain M A Sweetman, Christian Fufezan, Birgit Duempelfeld, Florian Braun, Christopher A Schofield, Hakan Keles, David Alvarado, Zhuo Wang, Keith H Jansson, Maria Fälth-Savitski, Edward Curry, Katja Remlinger, Euan A Stronach, Bin Feng, Geeta Sharma, Kevin Coleman, Paola Grandi, Marcus Bantscheff, Giovanna Bergamini
Synergistic effects of PARP inhibition and cholesterol biosynthesis pathway modulation. Cancer research communications (2024)
Gabriele Picco, Yanhua Rao, Angham Al Saedi, Yang Lee, Sara F Vieira, Shriram Bhosle, Kieron May, Carmen Herranz, Samantha J Walker, Raynold Shenje, Cansu Dincer, Freddy Gibson, Ruby Banerjee, Zoe Hewitson, Thilo Werner, Joshua E Cottom, Yang Peng, Nanhua Deng, Youyou Zhang, Eldridge N Nartey, Leng Nickels, Philip Landis, Daniela Conticelli, Katrina McCarten, Jacob T Bush, Mamta Sharma, Howard Lightfoot, David House, Emma Milford, Emma K Grant, Michal P Glogowski, Craig D Wagner, Marcus Bantscheff, Anna Rutkowska-Klute, null null, Francesca Zappacosta, Jonathan Pettinger, Syd Barthorpe, H Christian Eberl, Brian T Jones, Jessica L Schneck, Dennis J Murphy, Emile E Voest, Joshua P Taygerly, Michael P DeMartino, Matthew A Coelho, Jonathan Houseley, Geeta Sharma, Benjamin J Schwartz, Mathew J Garnett
Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells. Cancer discovery 14 (8) (2024)
Mira L Burtscher, Stephan Gade, Martín Garrido-Rodriguez, Anna Rutkowska, Thilo Werner, H Christian Eberl, Massimo Petretich, Natascha Knopf, Katharina Zirngibl, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff, Maria Fälth-Savitski, Julio Saez-Rodriguez
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition. Molecular systems biology 20 (4) (2024)
Joseph E Pero, Elizabeth A Mueller, Ashley M Adams, Ramona S Adolph, Parikshit Bagchi, Dale Balce, Marcus Bantscheff, Ona Barauskas, Istvan Bartha, Dana Bohan, Haiying Cai, Esteban Carabajal, James Cassidy, Matthew Cato, Khuram W Chaudhary, Dingjun Chen, Yi-Pei Chen, Christophe Colas, Isra Darwech, H Christian Eberl, Beth Fernandez, Earl Gordon, Johannes Grosse, Justin Hansen, Belinda E Hetzler, Seungmin Hwang, Sam Jeyasingh, Beatriz Kowalski, Stephanie Lehmann, Gary Lo, Michael McAllaster, Charles McHugh, Corey Momont, Zachary Newby, Maria Nigro, Fatai Oladunni, Malar Pannirselvam, Arnold Park, Neil Pearson, Andrew J Peat, Bob Plastridge, Rohit Ranjan, Pegah Safabakhsh, Nathan D Shapiro, Leah Soriaga, Neil Stokes, David Sweeney, Lindsey Talecki, Amalio Telenti, Ashley Terrell, Winston Tse, Lisha Wang, Shuya Wang, Laura Wedel, Thilo Werner, Deidre Dalmas Wilk, Samantha Yim, Jiayi Zhou
Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety. Journal of medicinal chemistry 67 (16) (2024)
Gabriele Picco, Yanhua Rao, Angham Al Saedi, Yang Lee, Sara F Vieira, Shriram Bhosle, Kieron May, Carmen Herranz, Samantha J Walker, Raynold Shenje, Cansu Dincer, Freddy Gibson, Ruby Banerjee, Zoe Hewitson, Thilo Werner, Joshua E Cottom, Yang Peng, Nanhua Deng, Philip Landis, Daniela Conticelli, Katrina McCarten, Jacob T Bush, Mamta Sharma, Howard Lightfoot, David House, Emma Milford, Emma K Grant, Michal P Glogowski, Craig D Wagner, Marcus Bantscheff, Anna Rutkowska-Klute, Cell Model Network Uk Group, Francesca Zappacosta, Jonathan Pettinger, Syd Barthorpe, H Christian Eberl, Brian T Jones, Jessica L Schneck, Dennis J Murphy, Emile E Voest, Joshua P Taygerly, Michael P DeMartino, Matthew A Coelho, Jonathan Houseley, Geeta Sharma, Benjamin J Schwartz, Mathew J Garnett
Novel WRN Helicase Inhibitors Selectively Target Microsatellite Unstable Cancer Cells. Cancer discovery (2024)
Joseph E Pero, Elizabeth A Mueller, Ashley M Adams, Ramona S Adolph, Parikshit Bagchi, Dale Balce, Marcus Bantscheff, Ona Barauskas, Istvan Bartha, Dana Bohan, Haiying Cai, Esteban Carabajal, James Cassidy, Matthew Cato, Khuram W Chaudhary, Dingjun Chen, Yi-Pei Chen, Christophe Colas, Isra Darwech, H Christian Eberl, Beth Fernandez, Earl Gordon, Johannes Grosse, Justin Hansen, Belinda E Hetzler, Seungmin Hwang, Sam Jeyasingh, Beatriz Kowalski, Stephanie Lehmann, Gary Lo, Michael McAllaster, Charles McHugh, Corey Momont, Zachary Newby, Maria Nigro, Fatai Oladunni, Malar Pannirselvam, Arnold Park, Neil Pearson, Andrew J Peat, Bob Plastridge, Rohit Ranjan, Pegah Safabakhsh, Nathan D Shapiro, Leah Soriaga, Neil Stokes, David Sweeney, Lindsey Talecki, Amalio Telenti, Ashley Terrell, Winston Tse, Lisha Wang, Shuya Wang, Laura Wedel, Thilo Werner, Deidre Dalmas Wilk, Samantha Yim, Jiayi Zhou
Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety. Journal of medicinal chemistry (2024)
Patricia Sauer, Marcus Bantscheff
Thermal Proteome Profiling for Drug Target Identification and Probing of Protein States. Methods in molecular biology (Clifton, N.J.) 2718 (2023)
Rüdiger Klein, Jennifer Geddes-McAlister, Matthias Mann, Marcus Bantscheff
The emerging role of mass spectrometry-based proteomics in drug discovery. Nature reviews. Drug discovery 21 (9) (2022)
Lauren B Arendse, James M Murithi, Tarrick Qahash, Charisse Flerida A Pasaje, Luiz C Godoy, Sumanta Dey, Liezl Gibhard, Sonja Ghidelli-Disse, Gerard Drewes, Marcus Bantscheff, Maria Jose Lafuente-Monasterio, Stephen Fienberg, Lynn Wambua, Samuel Gachuhi, Dina Coertzen, Mariëtte E van der Watt, Janette Reader, Ayesha S Aswat, Erica Erlank, Nelius Venter, Nimisha Mittal, Madeline R Luth, Sabine Ottilie, Elizabeth A Winzeler, Lizette Leonie Koekemoer, Lyn-Marié Birkholtz, Jacquin C Niles, Manuel Llinás, David A Fidock, Kelly Chibale
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages. Science translational medicine 14 (667) (2022)
Vinayak Singh, Anna E Grzegorzewicz, Stephen Fienberg, Rudolf Müller, Lutete Peguy Khonde, Olalla Sanz, Salvatore Alfonso, Beatriz Urones, Gerard Drewes, Marcus Bantscheff, Sonja Ghidelli-Disse, Thomas R Ioerger, Bhanupriya Angala, Jiuyu Liu, Richard E Lee, James C Sacchettini, Inna V Krieger, Mary Jackson, Kelly Chibale, Sandeep R Ghorpade
1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis . ACS infectious diseases 8 (11) (2022)
Sindhuja Sridharan, Alberto Hernandez-Armendariz, Nils Kurzawa, Clement M Potel, Danish Memon, Pedro Beltrao, Marcus Bantscheff, Wolfgang Huber, Sara Cuylen-Haering, Mikhail M Savitski
Systematic discovery of biomolecular condensate-specific protein phosphorylation. Nature chemical biology 18 (10) (2022)
Nico Zinn, Thilo Werner, Carola Doce, Toby Mathieson, Christine Boecker, Gavain Sweetman, Christian Fufezan, Marcus Bantscheff
Improved Proteomics-Based Drug Mechanism-of-Action Studies Using 16-Plex Isobaric Mass Tags. Journal of proteome research 20 (3) (2021)
Nils Kurzawa, Isabelle Becher, Sindhuja Sridharan, Holger Franken, André Mateus, Simon Anders, Marcus Bantscheff, Wolfgang Huber, Mikhail M Savitski
Author Correction: A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles. Nature communications 12 (1) (2021)
Aurélia C Balestra, Konstantinos Koussis, Natacha Klages, Steven A Howell, Helen R Flynn, Marcus Bantscheff, Carla Pasquarello, Abigail J Perrin, Lorenzo Brusini, Patrizia Arboit, Olalla Sanz, Laura Peces-Barba Castaño, Chrislaine Withers-Martinez, Alexandre Hainard, Sonja Ghidelli-Disse, Ambrosius P Snijders, David Andrew Baker, Michael J Blackman, Mathieu Brochet
Ca2+ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG. Science advances 7 (13) (2021)
Zlata Vershinin, Michal Feldman, Thilo Werner, Lital Estrella Weil, Margarita Kublanovsky, Elina Abaev-Schneiderman, Menachem Sklarz, Enid Y N Lam, Khawla Alasad, Sarah Picaud, Barak Rotblat, Ruth A McAdam, Vered Chalifa-Caspi, Marcus Bantscheff, Trevor Chapman, Huw D Lewis, Panagis Filippakopoulos, Mark A Dawson, Paola Grandi, Rabinder K Prinjha, Dan Levy
BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation. Science advances 7 (22) (2021)
Siqi Fang, Paul D W Kirk, Marcus Bantscheff, Kathryn S Lilley, Oliver M Crook
A Bayesian semi-parametric model for thermal proteome profiling. Communications biology 4 (1) (2021)
Mathias Kalxdorf, Ina Günthner, Isabelle Becher, Nils Kurzawa, Sascha Knecht, Mikhail M Savitski, H Christian Eberl, Marcus Bantscheff
Cell surface thermal proteome profiling tracks perturbations and drug targets on the plasma membrane. Nature methods 18 (1) (2021)
Melissa B Pappalardi, Kathryn Keenan, Mark Cockerill, Wendy A Kellner, Alexandra Stowell, Christian Sherk, Kristen Wong, Sarath Pathuri, Jacques Briand, Michael Steidel, Philip Chapman, Arthur Groy, Ashley K Wiseman, Charles F McHugh, Nino Campobasso, Alan P Graves, Emma Fairweather, Thilo Werner, Ali Raoof, Roger J Butlin, Lourdes Rueda, John R Horton, David T Fosbenner, Cunyu Zhang, Jessica L Handler, Morris Muliaditan, Makda Mebrahtu, Jon-Paul Jaworski, Dean E McNulty, Charlotte Burt, H Christian Eberl, Amy N Taylor, Thau Ho, Susan Merrihew, Shawn W Foley, Anna Rutkowska, Mei Li, Stuart P Romeril, Kristin Goldberg, Xing Zhang, Christopher S Kershaw, Marcus Bantscheff, Anthony J Jurewicz, Elisabeth Minthorn, Paola Grandi, Mehul Patel, Andrew B Benowitz, Helai P Mohammad, Aidan G Gilmartin, Rabinder K Prinjha, Donald Ogilvie, Christopher Carpenter, Dirk Heerding, Stephen B Baylin, Peter A Jones, Xiaodong Cheng, Bryan W King, Juan I Luengo, Allan Michael Jordan, Ian Waddell, Ryan G Kruger, Michael T McCabe
Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nature cancer 2 (10) (2021)
Bingyu Yan, Tilo Freiwald, Daniel Chauss, Luopin Wang, Erin E West, Carmen Mirabelli, Charles J Zhang, Eva-Maria Nichols, Nazish Malik, Richard Gregory, Marcus Bantscheff, Sonja Ghidelli-Disse, Martin Kolev, Tristan Frum, Jason R Spence, Jonathan Z Sexton, Konstantinos D Alysandratos, Darrell N Kotton, Stefania Pittaluga, Jack Bibby, Nathalie Niyonzima, Matthew R Olson, Shahram Kordasti, Didier Portilla, Christiane E Wobus, Arian Dominic John Laurence, Michail S Lionakis, Claudia Kemper, Behdad Afzali, Majid Kazemian
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation. Science immunology 6 (58) (2021)
Ami Ketley, Marzena Wojciechowska, Sonja Ghidelli-Disse, Paul Bamborough, Tushar K Ghosh, Marta Lopez Morato, Saam Sedehizadeh, Naveed Altaf Malik, Zhenzhi Tang, Paulina Powalowska, Matthew K Tanner, Rudolf Billeter-Clark, Rebecca C Trueman, Philippine C Geiszler, Alessandra Agostini, Othman Othman, Markus Boesche, Marcus Bantscheff, Martin Rüdiger, Danuta E Mossakowska, David Harold Drewry, William J Zuercher, Charles A Thornton, Gerard Drewes, Iain Uings, Christopher J Hayes, J David Brook
CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model. Science translational medicine 12 (541) (2021)
Robert P Law, Joao Nunes, Chun-Wa Chung, Marcus Bantscheff, Karol Buda, Han Dai, John P Evans, Adam Flinders, Diana Klimaszewska, Antonia J Lewis, Marcel Muelbaier, Paul Scott-Stevens, Peter Stacey, Christopher J Tame, Gillian F Watt, Nico Zinn, Markus A Queisser, John D Harling, Andrew B Benowitz
Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs. Angewandte Chemie (International ed. in English) 60 (43) (2021)
Julia Mergner, Martin Frejno, Markus List, Michael Papacek, Xia Chen, Ajeet Chaudhary, Patroklos Samaras, Sandra Richter, Hiromasa Shikata, Maxim Messerer, Daniel Lang, Stefan Altmann, Philipp Cyprys, Daniel P Zolg, Toby Mathieson, Marcus Bantscheff, Rashmi R Hazarika, Tobias K Schmidt, Corinna Dawid, Andreas Dunkel, Thomas Hofmann, Stefanie Sprunck, Pascal Falter-Braun, Frank Johannes, Klaus F X Mayer, Gerd Jürgens, Mathias Wilhelm, Jan Baumbach, Erwin Grill, Kay Schneitz, Claus Schwechheimer, Bernhard Kuster
Mass-spectrometry-based draft of the Arabidopsis proteome. Nature 579 (7799) (2020)
Nils Kurzawa, Isabelle Becher, Sindhuja Sridharan, Holger Franken, André Mateus, Simon Anders, Marcus Bantscheff, Wolfgang Huber, Mikhail M Savitski
A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles. Nature communications 11 (1) (2020)
Anna Jarzab, Nils Kurzawa, Thomas Hopf, Matthias Moerch, Jana Zecha, Niels Leijten, Yangyang Bian, Eva Musiol, Melanie Maschberger, Gabriele Stoehr, Isabelle Becher, Charlotte Daly, Patroklos Samaras, Julia Mergner, Britta Spanier, Angel Angelov, Thilo Werner, Marcus Bantscheff, Mathias Wilhelm, Martin Klingenspor, Simone Lemeer, Wolfgang Liebl, Hannes Hahne, Mikhail M Savitski, Bernhard Kuster
Meltome atlas-thermal proteome stability across the tree of life. Nature methods 17 (5) (2020)
Alina Mares, Afjal H Miah, Ian E D Smith, Mark Rackham, Aditya Raymond Thawani, Jenni Cryan, Pamela A Haile, Bartholomew J Votta, Allison M Beal, Carol Capriotti, Michael A Reilly, Don T Fisher, Nico Zinn, Marcus Bantscheff, Thomas T MacDonald, Anna Vossenkamper, Phoebe Dace, Ian Churcher, Andrew B Benowitz, Gillian F Watt, Jane Denyer, Paul Scott-Stevens, John D Harling
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2. Communications biology 3 (1) (2020)
Zoë A Henley, Augustin Amour, Nick Barton, Marcus Bantscheff, Giovanna Bergamini, Sophie M Bertrand, Máire Convery, Kenneth Down, Birgit Dümpelfeld, Chris D Edwards, Paola Grandi, Paul M Gore, Steve Keeling, Stefano Livia, David Mallett, Aoife Maxwell, Mark Price, Christina Rau, Friedrich B M Reinhard, James Rowedder, Paul Rowland, Jonathan A Taylor, Daniel A Thomas, Edith M Hessel, J Nicole Hamblin
Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity Target. Journal of medicinal chemistry 63 (2) (2020)
Jessica Perrin, Thilo Werner, Nils Kurzawa, Anna Rutkowska, Dorothee D Childs, Mathias Kalxdorf, Daniel Poeckel, Eugenia Stonehouse, Katrin Strohmer, Bianca Heller, Douglas W Thomson, Jana Krause, Isabelle Becher, H Christian Eberl, Johanna Vappiani, Daniel C Sevin, Christina E Rau, Holger Franken, Wolfgang Huber, Maria Faelth-Savitski, Mikhail M Savitski, Marcus Bantscheff, Giovanna Bergamini
Identifying drug targets in tissues and whole blood with thermal-shift profiling. Nature biotechnology 38 (3) (2020)
Omer Gilan, Inmaculada Rioja, Kathy Knezevic, Matthew J Bell, Miriam M Yeung, Nicola R Harker, Enid Y N Lam, Chun-Wa Chung, Paul Bamborough, Massimo Petretich, Marjeta Urh, Stephen J Atkinson, Anna K Bassil, Emma J Roberts, Dane Vassiliadis, Marian L Burr, Alex G S Preston, Christopher R Wellaway, Thilo Werner, James R Gray, Anne-Marie Michon, Thomas Gobbetti, Vinod Kumar, Peter E Soden, Andrea Haynes, Johanna Vappiani, David F Tough, Simon J Taylor, Sarah-Jane Dawson, Marcus Bantscheff, Matthew Lindon, Gerard Drewes, Emmanuel H Demont, Danette L Daniels, Paola Grandi, Rabinder K Prinjha, Mark A Dawson
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation. Science (New York, N.Y.) 368 (6489) (2020)
Sindhuja Sridharan, Nils Kurzawa, Thilo Werner, Ina Günthner, Dominic Helm, Wolfgang Huber, Marcus Bantscheff, Mikhail M Savitski
Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP. Nature communications 10 (1) (2019)
Arne H Smits, Frederik Ziebell, Gerard Joberty, Nico Zinn, William F Mueller, Sandra Clauder-Münster, Dirk Eberhard, Maria Fälth Savitski, Paola Grandi, Petra Jakob, Anne-Marie Michon, Hanice Sun, Karen Tessmer, Tilmann Bürckstümmer, Marcus Bantscheff, Lars M Steinmetz, Gerard Drewes, Wolfgang Huber
Biological plasticity rescues target activity in CRISPR knock outs. Nature methods 16 (11) (2019)
H Christian Eberl, Thilo Werner, Friedrich B M Reinhard, Stephanie Lehmann, Douglas Thomson, Peiling Chen, Cunyu Zhang, Christina Rau, Marcel Muelbaier, Gerard Drewes, David Harold Drewry, Marcus Bantscheff
Chemical proteomics reveals target selectivity of clinical Jak inhibitors in human primary cells. Scientific reports 9 (1) (2019)
Christopher P Tinworth, Hannah Lithgow, Lars Dittus, Zuni I Bassi, Sophie E Hughes, Marcel Muelbaier, Han Dai, Ian E D Smith, William J Kerr, Glenn A Burley, Marcus Bantscheff, John D Harling
PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding. ACS chemical biology 14 (3) (2019)
Samuel E Dalton, Lars Dittus, Daniel A Thomas, Máire A Convery, Joao Nunes, Jacob T Bush, John P Evans, Thilo Werner, Marcus Bantscheff, John A Murphy, Sebastien Campos
Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition. Journal of the American Chemical Society 140 (3) (2018)
Toby Mathieson, Holger Franken, Jan Kosinski, Nils Kurzawa, Nico Zinn, Gavain Sweetman, Daniel Poeckel, Vikram S Ratnu, Maike Schramm, Isabelle Becher, Michael Steidel, Kyung-Min Noh, Giovanna Bergamini, Martin Beck, Marcus Bantscheff, Mikhail M Savitski
Systematic analysis of protein turnover in primary cells. Nature communications 9 (1) (2018)
Mathias Kalxdorf, Stephan Gade, H Christian Eberl, Marcus Bantscheff
Monitoring Cell-surface N-Glycoproteome Dynamics by Quantitative Proteomics Reveals Mechanistic Insights into Macrophage Differentiation. Molecular & cellular proteomics : MCP 16 (5) (2017)
Lars Dittus, Thilo Werner, Marcel Muelbaier, Marcus Bantscheff
Differential Kinobeads Profiling for Target Identification of Irreversible Kinase Inhibitors. ACS chemical biology 12 (10) (2017)
Isabelle Becher, Thilo Werner, Carola Doce, Esther A Zaal, Ina Tögel, Crystal A Khan, Anne Rueger, Marcel Muelbaier, Elsa Salzer, Celia R Berkers, Paul F Fitzpatrick, Marcus Bantscheff, Mikhail M Savitski
Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat. Nature chemical biology 12 (11) (2016)
Jonathan A G Cox, Katherine A Abrahams, Carlos Alemparte, Sonja Ghidelli-Disse, Joaquín Rullas, Iñigo Angulo-Barturen, Albel Singh, Sudagar S Gurcha, Vijayashankar Nataraj, Stephen Bethell, Modesto J Remuiñán, Lourdes Encinas, Peter J Jervis, Nicholas C Cammack, Apoorva Bhatt, Ulrich Kruse, Marcus Bantscheff, Klaus Fütterer, David Barros, Lluis Ballell, Gerard Drewes, Gurdyal S Besra
THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. Nature microbiology 1 (2016)
Katherine A Abrahams, Chun-Wa Chung, Sonja Ghidelli-Disse, Joaquín Rullas, María José Rebollo-López, Sudagar S Gurcha, Jonathan A G Cox, Alfonso Mendoza, Elena Jiménez-Navarro, María Santos Martínez-Martínez, Margarete Neu, Anthony Shillings, Paul Homes, Argyrides Argyrou, Ruth Casanueva, Nicholas J Loman, Patrick J Moynihan, Joël Lelièvre, Carolyn Selenski, Matthew Axtman, Laurent Kremer, Marcus Bantscheff, Iñigo Angulo-Barturen, Mónica Cacho Izquierdo, Nicholas C Cammack, Gerard Drewes, Lluis Ballell, David Barros, Gurdyal S Besra, Robert H Bates
Identification of KasA as the cellular target of an anti-tubercular scaffold. Nature communications 7 (2016)
Julianty Frost, Carles Galdeano, Pedro Soares, Morgan S Gadd, Katarzyna M Grzes, Lucy Ellis, Ola Epemolu, Satoko Shimamura, Marcus Bantscheff, Paola Grandi, Kevin D Read, Doreen A Cantrell, Sonia Rocha, Alessio Ciulli
Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition. Nature communications 7 (2016)
Holger Franken, Toby Mathieson, Dorothee Childs, Gavain M A Sweetman, Thilo Werner, Ina Tögel, Carola Doce, Stephan Gade, Marcus Bantscheff, Gerard Drewes, Friedrich B M Reinhard, Wolfgang Huber, Mikhail M Savitski
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry. Nature protocols 10 (10) (2015)
Friedrich B M Reinhard, Dirk Eberhard, Thilo Werner, Holger Franken, Dorothee Childs, Carola Doce, Maria Fälth Savitski, Wolfgang Huber, Marcus Bantscheff, Mikhail M Savitski, Gerard Drewes
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins. Nature methods 12 (12) (2015)