Frank J M van Kuppeveld (Frank J van Kuppeveld, Frank Van Kuppeveld, Frank van Kuppeveld, F J M van Kuppeveld)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 48

Top Topics

Dna Damage Response

Protein Protein

Endoplasmic Reticulum

Top Venues

Nature communications

Science signaling

Nature microbiology

This page only lists publications with an associated author ORCID identifier.

Publications

Lonneke V Nouwen, Martijn Breeuwsma, Esther A Zaal, Chris H A van de Lest, Inge Buitendijk, Marleen Zwaagstra, Pascal Balić, Dmitri V Filippov, Celia R Berkers, Frank J M van Kuppeveld
Modulation of nucleotide metabolism by picornaviruses. PLoS pathogens 20 (3) (2024)
Mirte N Pascha, M Ballegeer, M C Roelofs, Leander Meuris, I C Albulescu, Frank J M van Kuppeveld, Daniel L Hurdiss, Berend-Jan Bosch, T Zeev-Ben-Mordehai, Xavier Saelens, Cornelis A M de Haan
Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge. NPJ vaccines 9 (1) (2024)
Lonneke V Nouwen, Martijn Breeuwsma, Esther A Zaal, Chris H A van de Lest, Inge Buitendijk, Marleen Zwaagstra, Pascal Balić, Dmitri V Filippov, Celia R Berkers, Frank J M van Kuppeveld
Modulation of nucleotide metabolism by picornaviruses. PLoS pathogens 20 (3) (2024)
Wenjuan Du, Oliver J Debski-Antoniak, Dubravka Drabek, Rien van Haperen, Melissa van Dortmondt, Joline van der Lee, Ieva Drulyte, Frank J M van Kuppeveld, Frank Grosveld, Daniel L Hurdiss, Berend-Jan Bosch
Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein. Nature communications 15 (1) (2024)
Rutger D Luteijn, Sypke R van Terwisga, Jill E Ver Eecke, Liberty Onia, Shivam A Zaver, Joshua J Woodward, Richard W Wubbolts, David H Raulet, Frank J M van Kuppeveld
The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P. Science signaling 17 (827) (2024)
Rutger D Luteijn, Sypke R van Terwisga, Jill E Ver Eecke, Liberty Onia, Shivam A Zaver, Joshua J Woodward, Richard W Wubbolts, David H Raulet, Frank J M van Kuppeveld
The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P. Science signaling 17 (827) (2024)
Rutger D Luteijn, Frank J M van Kuppeveld
Author Correction: Rhinoviruses usurp STING for replication. Nature microbiology (2024)
Wenjuan Du, Oliver J Debski-Antoniak, Dubravka Drabek, Rien van Haperen, Melissa van Dortmondt, Joline van der Lee, Ieva Drulyte, Frank J M van Kuppeveld, Frank Grosveld, Daniel L Hurdiss, Berend-Jan Bosch
Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein. Nature communications 15 (1) (2024)
Wenjuan Du, Oliver J Debski-Antoniak, Dubravka Drabek, Rien van Haperen, Melissa van Dortmondt, Joline van der Lee, Ieva Drulyte, Frank J M van Kuppeveld, Frank Grosveld, Daniel L Hurdiss, Berend-Jan Bosch
Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein. Nature communications 15 (1) (2024)
Rutger D Luteijn, Sypke R van Terwisga, Jill E Ver Eecke, Liberty Onia, Shivam A Zaver, Joshua J Woodward, Richard W Wubbolts, David H Raulet, Frank J M van Kuppeveld
The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P. Science signaling 17 (827) (2024)
Mirte N Pascha, M Ballegeer, M C Roelofs, Leander Meuris, I C Albulescu, Frank J M van Kuppeveld, Daniel L Hurdiss, Berend-Jan Bosch, T Zeev-Ben-Mordehai, Xavier Saelens, Cornelis A M de Haan
Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge. NPJ vaccines 9 (1) (2024)
Wenjuan Du, Oliver J Debski-Antoniak, Dubravka Drabek, Rien van Haperen, Melissa van Dortmondt, Joline van der Lee, Ieva Drulyte, Frank J M van Kuppeveld, Frank Grosveld, Daniel L Hurdiss, Berend-Jan Bosch
Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein. Nature communications 15 (1) (2024)
Rutger D Luteijn, Sypke R van Terwisga, Jill E Ver Eecke, Liberty Onia, Shivam A Zaver, Joshua J Woodward, Richard W Wubbolts, David H Raulet, Frank J M van Kuppeveld
The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P. Science signaling 17 (827) (2024)
Rutger D Luteijn, Sypke R van Terwisga, Jill E Ver Eecke, Liberty Onia, Shivam A Zaver, Joshua J Woodward, Richard W Wubbolts, David H Raulet, Frank J M van Kuppeveld
The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P. Science signaling 17 (827) (2024)
Lonneke V Nouwen, Martijn Breeuwsma, Esther A Zaal, Chris H A van de Lest, Inge Buitendijk, Marleen Zwaagstra, Pascal Balić, Dmitri V Filippov, Celia R Berkers, Frank J M van Kuppeveld
Modulation of nucleotide metabolism by picornaviruses. PLoS pathogens 20 (3) (2024)
Rutger D Luteijn, Sypke R van Terwisga, Jill E Ver Eecke, Liberty Onia, Shivam A Zaver, Joshua J Woodward, Richard W Wubbolts, David H Raulet, Frank J M van Kuppeveld
The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P. Science signaling 17 (827) (2024)
Jordi Doijen, Koen Temmerman, Christel Van den Eynde, Annick Diels, Nick Van den Broeck, Michiel Van Gool, Inha Heo, Steffen Jaensch, Marleen Zwaagstra, Mayra Diosa Toro, Winston Chiu, Steven De Jonghe, Pieter Leyssen, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Lore Verschueren, Christophe Buyck, Frank J M van Kuppeveld, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Identification of Z-Tyr-Ala-CHN 2 , a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2. Microorganisms 11 (3) (2023)
Mirjam B H M Duijvestijn, Nancy N M P Schuurman, Johannes C M Vernooij, Michelle A J M van Leeuwen, Berend-Jan Bosch, Judith van den Brand, Jaap A Wagenaar, Frank J M van Kuppeveld, Herman F Egberink, Josanne H Verhagen
Serological Survey of Retrovirus and Coronavirus Infections, including SARS-CoV-2, in Rural Stray Cats in The Netherlands, 2020-2022. Viruses 15 (7) (2023)
Matti Feije Pronker, Robert Creutznacher, Ieva Drulyte, Ruben J G Hulswit, Zeshi Li, Frank J M van Kuppeveld, Joost Snijder, Yifei Lang, Berend-Jan Bosch, Geert-Jan Boons, Martin Frank, Raoul J de Groot, Daniel L Hurdiss
Sialoglycan binding triggers spike opening in a human coronavirus. Nature (2023)
Jordi Doijen, Koen Temmerman, Christel Van den Eynde, Annick Diels, Nick Van den Broeck, Michiel Van Gool, Inha Heo, Steffen Jaensch, Marleen Zwaagstra, Mayra Diosa Toro, Winston Chiu, Steven De Jonghe, Pieter Leyssen, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Lore Verschueren, Christophe Buyck, Frank J M van Kuppeveld, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Identification of Z-Tyr-Ala-CHN 2 , a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2. Microorganisms 11 (3) (2023)
Jordi Doijen, Koen Temmerman, Christel Van den Eynde, Annick Diels, Nick Van den Broeck, Michiel Van Gool, Inha Heo, Steffen Jaensch, Marleen Zwaagstra, Mayra Diosa Toro, Winston Chiu, Steven De Jonghe, Pieter Leyssen, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Lore Verschueren, Christophe Buyck, Frank J M van Kuppeveld, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Identification of Z-Tyr-Ala-CHN 2 , a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2. Microorganisms 11 (3) (2023)
Chiara Aloise, Jelle G Schipper, Arno van Vliet, Judith Oymans, Tim Donselaar, Daniel L Hurdiss, Raoul J de Groot, Frank J M van Kuppeveld
SARS-CoV-2 nucleocapsid protein inhibits the PKR-mediated integrated stress response through RNA-binding domain N2b. PLoS pathogens 19 (8) (2023)
Lucas J M Bruurs, Micha Müller, Jelle G Schipper, Huib H Rabouw, Sanne Boersma, Frank J M van Kuppeveld, Marvin E Tanenbaum
Antiviral responses are shaped by heterogeneity in viral replication dynamics. Nature microbiology (2023)
Louisa E Wallace, Erik de Vries, Frank J M van Kuppeveld, Cornelis A M de Haan
Neuraminidase-dependent entry of influenza A virus is determined by hemagglutinin receptor-binding specificity. Journal of virology (2023)
Mirte N Pascha, Vito Thijssen, Julia E Egido, Mirte W Linthorst, Jipke H van Lanen, David A A van Dongen, Antonius J P Hopstaken, Frank J M van Kuppeveld, Joost Snijder, Cornelis A M de Haan, Seino A K Jongkees
Inhibition of H1 and H5 Influenza A Virus Entry by Diverse Macrocyclic Peptides Targeting the Hemagglutinin Stem Region. ACS chemical biology 17 (9) (2022)
Rutger D Luteijn, Frank J M van Kuppeveld
Rhinoviruses usurp STING for replication. Nature microbiology 7 (5) (2022)
Wenjuan Du, Daniel L Hurdiss, Dubravka Drabek, Anna Z Mykytyn, Franziska K Kaiser, Mariana Gonzalez Hernandez, Diego Muñoz-Santos, Mart M Lamers, Rien van Haperen, Wentao Li, Ieva Drulyte, Chunyan Wang, Isabel Sola, Federico Armando, Georg Beythien, Malgorzata Ciurkiewicz, Wolfgang Baumgärtner, Kate Guilfoyle, Tony Smits, Joline van der Lee, Frank J M van Kuppeveld, Geert van Amerongen, Bart L Haagmans, Luis Enjuanes, Albert D M E Osterhaus, Frank Grosveld, Berend-Jan Bosch
An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern. Science immunology 7 (73) (2022)
Chunyan Wang, Emma L Hesketh, Tatiana M Shamorkina, Wentao Li, Peter J Franken, Dubravka Drabek, Rien van Haperen, Sarah Townend, Frank J M van Kuppeveld, Frank Grosveld, Neil A Ranson, Joost Snijder, Raoul J de Groot, Daniel L Hurdiss, Berend-Jan Bosch
Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes. Nature communications 13 (1) (2022)
Daniel L Hurdiss, Priscila El Kazzi, Lisa Bauer, Nicolas Papageorgiou, François P Ferron, Tim Donselaar, Arno L W van Vliet, Tatiana M Shamorkina, Joost Snijder, Bruno Canard, Etienne Decroly, Andrea Brancale, Tzviya Zeev-Ben-Mordehai, Friedrich G Förster, Frank J M van Kuppeveld, Bruno Coutard
Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex. Science advances 8 (1) (2022)
Susanne G van der Grein, Kyra A Y Defourny, Huib H Rabouw, Soenita S Goerdayal, Martijn J C van Herwijnen, Richard W Wubbolts, A F Maarten Altelaar, Frank J M van Kuppeveld, Esther N M Nolte-'t Hoen
The encephalomyocarditis virus Leader promotes the release of virions inside extracellular vesicles via the induction of secretory autophagy. Nature communications 13 (1) (2022)
Mengying Liu, Liane Z X Huang, Anthony A Smits, Christian Büll, Yoshiki Narimatsu, Frank J M van Kuppeveld, Henrik Clausen, Cornelis A M de Haan, Erik de Vries
Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions. Nature communications 13 (1) (2022)
Xiaoyao Yang, Chiara Aloise, Arno L W van Vliet, Marleen Zwaagstra, Heyrhyoung Lyoo, An-Chun Cheng, Frank J M van Kuppeveld
Proteolytic Activities of Enterovirus 2A Do Not Depend on Its Interaction with SETD3. Viruses 14 (7) (2022)
Janeri Fröberg, Joshua Gillard, Ria Philipsen, Kjerstin Lanke, Joyce Rust, Diana van Tuijl, Karina Teelen, Teun Bousema, Elles Simonetti, Christa E van der Gaast-de Jongh, Mariska Bos, Frank J M van Kuppeveld, Berend-Jan Bosch, Marrigje Nabuurs-Franssen, Nannet van der Geest-Blankert, Charlotte van Daal, Martijn A Huynen, Marien I de Jonge, Dimitri A Diavatopoulos
SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms. Nature communications 12 (1) (2021)
Juliette Fedry, Daniel L Hurdiss, Chunyan Wang, Wentao Li, Gonzalo Obal, Ieva Drulyte, Wenjuan Du, Stuart C Howes, Frank J M van Kuppeveld, Friedrich G Förster, Berend-Jan Bosch
Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11. Science advances 7 (23) (2021)
Jean Paul Ten Klooster, Marianne Bol-Schoenmakers, Kitty van Summeren, Arno L W van Vliet, Cornelis A M de Haan, Frank J M van Kuppeveld, Saertje Verkoeijen, Raymond Pieters
Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine. Communications biology 4 (1) (2021)
Chunyan Wang, Rien van Haperen, Javier Gutierrez-Alvarez, Wentao Li, Nisreen M A Okba, Irina Albulescu, Ivy Widjaja, Brenda van Dieren, Raúl Fernández-Delgado, Isabel Sola, Daniel L Hurdiss, Olalekan Daramola, Frank Grosveld, Frank J M van Kuppeveld, Bart L Haagmans, Luis Enjuanes, Dubravka Drabek, Berend-Jan Bosch
A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies. Nature communications 12 (1) (2021)
Yan Ni, Bas J H M Rosier, Eva A van Aalen, Eva T L Hanckmann, Lieuwe Biewenga, Anna-Maria Makri Pistikou, Bart Timmermans, Chris Vu, Sophie Roos, Remco Arts, Wentao Li, Tom F A de Greef, Marcel M G J van Borren, Frank J M van Kuppeveld, Berend-Jan Bosch, Maarten Merkx
A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays. Nature communications 12 (1) (2021)
Wenjuan Du, Margreet A Wolfert, Ben P H Peeters, Frank J M van Kuppeveld, Geert-Jan Boons, Erik de Vries, Cornelis A M de Haan
Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin. PLoS pathogens 16 (8) (2020)
Lisa Bauer, Roberto Manganaro, Birgit Zonsics, Daniel L Hurdiss, Marleen Zwaagstra, Tim Donselaar, Naemi G E Welter, Regina G D M van Kleef, Moira Lorenzo Lopez, Federica Bevilacqua, Thamidur Raman, Salvatore Ferla, Marcella Bassetto, Johan Neyts, Jeroen R P M Strating, Remco H S Westerink, Andrea Brancale, Frank J M van Kuppeveld
Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C. PLoS biology 18 (11) (2020)
Simon Dirmeier, Christopher Daechert, Martijn J van Hemert, Ali Tas, Natacha S Ogando, Frank J M van Kuppeveld, Ralf F W Bartenschlager, Lars Kaderali, Marco Binder, Niko Beerenwinkel
Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation. PLoS computational biology 16 (2) (2020)
Daniel L Hurdiss, Ieva Drulyte, Yifei Lang, Tatiana M Shamorkina, Matti Feije Pronker, Frank J M van Kuppeveld, Joost Snijder, Raoul J de Groot
Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans. Nature communications 11 (1) (2020)
Linda J Visser, Chiara Aloise, Kirby N Swatek, Gisselle N Medina, Karin M Olek, Huib H Rabouw, Raoul J de Groot, Martijn A Langereis, Teresa de Los Santos, David Komander, Tim Skern, Frank J M van Kuppeveld
Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression. PLoS pathogens 16 (7) (2020)
Piero Giansanti, Jeroen R P M Strating, Kyra A Y Defourny, Ieva Cesonyte, Alexia M S Bottino, Harm Post, Ekaterina G Viktorova, Vien Quang Tri Ho, Martijn A Langereis, George A Belov, Esther N M Nolte-'t Hoen, Albert J R Heck, Frank J M van Kuppeveld
Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection. Nature communications 11 (1) (2020)
Huib H Rabouw, Linda J Visser, Tim Casper Passchier, Martijn A Langereis, Fan Liu, Piero Giansanti, Arno L W van Vliet, José G Dekker, Susanne G van der Grein, Jesús G Saucedo, Aditya A Anand, Mikael E Trellet, Alexandre M J J Bonvin, Peter Walter, Albert J R Heck, Raoul J de Groot, Frank J M van Kuppeveld
Inhibition of the integrated stress response by viral proteins that block p-eIF2-eIF2B association. Nature microbiology 5 (11) (2020)
Jacob A McPhail, Heyrhyoung Lyoo, Joshua G Pemberton, Reece M Hoffmann, Wendy van Elst, Jeroen R P M Strating, Meredith L Jenkins, Jordan T B Stariha, Cameron J Powell, Martin J Boulanger, Tamas Balla, Frank J M van Kuppeveld, John E Burke
Characterization of the c10orf76-PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication. EMBO reports 21 (2) (2019)
Liang Sun, Aloys Tijsma, Carmen Mirabelli, Jim Baggen, Maryam Wahedi, David Franco, Armando De Palma, Pieter Leyssen, Erik Verbeken, Frank J M van Kuppeveld, Johan Neyts, Hendrik-Jan Thibaut
Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence. Emerging microbes & infections 8 (1) (2019)
Lisa Bauer, Roberto Manganaro, Birgit Zonsics, Jeroen R P M Strating, Priscila El Kazzi, Moira Lorenzo Lopez, Rachel Ulferts, Clara van Hoey, Maria J Maté, Thierry Langer, Bruno Coutard, Andrea Brancale, Frank J M van Kuppeveld
Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner. ACS infectious diseases 5 (9) (2019)
Eveline Kindler, Cristina Gil-Cruz, Julia Spanier, Yize Li, Jochen Wilhelm, Huib H Rabouw, Roland Züst, Mihyun Hwang, Philip Vkovski, Hanspeter Stalder, Sabrina Marti, Matthias Habjan, Luisa Cervantes-Barragan, Ruth Elliot, Nadja Karl, Christina Gaughan, Frank J M van Kuppeveld, Robert H Silverman, Markus Keller, Burkhard Ludewig, Cornelia C Bergmann, John Ziebuhr, Susan R Weiss, Ulrich Kalinke, Volker Thiel
Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS pathogens 13 (2) (2017)