Johan Neyts (J Neyts)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 98

Top Venues

Viruses

Nature communications

Microorganisms

Nature

Rega Institute, KU Leuven

KU Leuven (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Rega Institute, KU Leuven

Belgium

Full Professor :: Microbiology and Immunology/Laboratory of Virology and Chemotherapy

KU Leuven

Belgium

Co-founder and Chief Scientific Officer of Okapi Sciences (Antivirals for Animals [www.okapi-sciences.com] a Rega / KU Leuven spin-off :: Microbiology and Immunology/Laboratory of Virology and Chemotherapy

KU Leuven

Belgium

Professsor of Virology, Faculty of Medicine :: Microbiology and Immunology/Laboratory of Virology and Chemotherapy

KU Leuven

Belgium

Associate Professor of Virology, Faculty of Medicine :: Microbiology and Immunology/Laboratory of Virology and Chemotherapy

KU Leuven

Belgium

Assistant Professor of Virology, Faculty of Medicine :: Microbiology and Immunology/Laboratory of Virology and Chemotherapy

KU Leuven

Belgium

Post-doctoral Research Assistant of the Fund for Scientific Research (Flanders) :: Microbiology and Immunology/Laboratory of Virology and Chemotherapy

University of North Carolina

United States

Post-doctoral stay at the Lineberger Comprehenseive Cancer Center :: Lab of Prof. Dr. J.S. Pagano, Chappel Hill

Military Hospital

Belgium

Military service (8 months) :: Laboratory of Zoonosis

KU Leuven

Belgium

Research Assistant of the Belgian National Fund for Scientific Research :: Microbiology and Immunology/Laboratory of Virology and Chemotherapy

KU Leuven

Belgium

Assistant (promotor Prof. Dr. E. De Clercq) :: Microbiology and Immunology/Laboratory of Virology and Chemotherapy

Education History

KU Leuven

Belgium

PHD :: Biological Sciences

KU Leuven

Belgium

MSC :: Biological Sciences

Publications

Dominik Kiemel, Ann-Sophie Helene Kroell, Solène Denolly, Uta Haselmann, Jean-François Bonfanti, Jose Ignacio Andres, Brahma Ghosh, Peggy Geluykens, Suzanne J F Kaptein, Lucas Wilken, Pietro Scaturro, Johan Neyts, Marnix Van Loock, Olivia Goethals, Ralf F W Bartenschlager
Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation. Nature communications 15 (1) (2024)
Rana Abdelnabi, Ria Lassaunière, Piet Maes, Birgit Weynand, Johan Neyts
Comparing the Infectivity of Recent SARS-CoV-2 Omicron Sub-Variants in Syrian Hamsters. Viruses 16 (1) (2024)
Rana Abdelnabi, Ria Lassaunière, Piet Maes, Birgit Weynand, Johan Neyts
Comparing the Infectivity of Recent SARS-CoV-2 Omicron Sub-Variants in Syrian Hamsters. Viruses 16 (1) (2024)
Rana Abdelnabi, Ria Lassaunière, Piet Maes, Birgit Weynand, Johan Neyts
Comparing the Infectivity of Recent SARS-CoV-2 Omicron Sub-Variants in Syrian Hamsters. Viruses 16 (1) (2024)
Rana Abdelnabi, Ria Lassaunière, Piet Maes, Birgit Weynand, Johan Neyts
Comparing the Infectivity of Recent SARS-CoV-2 Omicron Sub-Variants in Syrian Hamsters. Viruses 16 (1) (2024)
Li-Hsin Li, Winston Chiu, Yun-An Huang, Madina Rasulova, Thomas Vercruysse, Hendrik-Jan Thibaut, Sebastiaan Ter Horst, Joana Rocha-Pereira, Greet Vanhoof, Doortje Borrenberghs, Olivia Goethals, Suzanne J F Kaptein, Pieter Leyssen, Johan Neyts, Kai Dallmeier
Multiplexed multicolor antiviral assay amenable for high-throughput research. Nature communications 15 (1) (2024)
Rana Abdelnabi, Ria Lassaunière, Piet Maes, Birgit Weynand, Johan Neyts
Comparing the Infectivity of Recent SARS-CoV-2 Omicron Sub-Variants in Syrian Hamsters. Viruses 16 (1) (2024)
Li-Hsin Li, Winston Chiu, Yun-An Huang, Madina Rasulova, Thomas Vercruysse, Hendrik-Jan Thibaut, Sebastiaan Ter Horst, Joana Rocha-Pereira, Greet Vanhoof, Doortje Borrenberghs, Olivia Goethals, Suzanne J F Kaptein, Pieter Leyssen, Johan Neyts, Kai Dallmeier
Multiplexed multicolor antiviral assay amenable for high-throughput research. Nature communications 15 (1) (2024)
Dominik Kiemel, Ann-Sophie Helene Kroell, Solène Denolly, Uta Haselmann, Jean-François Bonfanti, Jose Ignacio Andres, Brahma Ghosh, Peggy Geluykens, Suzanne J F Kaptein, Lucas Wilken, Pietro Scaturro, Johan Neyts, Marnix Van Loock, Olivia Goethals, Ralf F W Bartenschlager
Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation. Nature communications 15 (1) (2024)
Dominik Kiemel, Ann-Sophie Helene Kroell, Solène Denolly, Uta Haselmann, Jean-François Bonfanti, Jose Ignacio Andres, Brahma Ghosh, Peggy Geluykens, Suzanne J F Kaptein, Lucas Wilken, Pietro Scaturro, Johan Neyts, Marnix Van Loock, Olivia Goethals, Ralf F W Bartenschlager
Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation. Nature communications 15 (1) (2024)
Li-Hsin Li, Winston Chiu, Yun-An Huang, Madina Rasulova, Thomas Vercruysse, Hendrik-Jan Thibaut, Sebastiaan Ter Horst, Joana Rocha-Pereira, Greet Vanhoof, Doortje Borrenberghs, Olivia Goethals, Suzanne J F Kaptein, Pieter Leyssen, Johan Neyts, Kai Dallmeier
Multiplexed multicolor antiviral assay amenable for high-throughput research. Nature communications 15 (1) (2024)
Yuxia Lin, Mona Khan, Birgit Weynand, Manon Laporte, Frank Coenjaerts, Darius Babusis, John P Bilello, Peter Mombaerts, Dirk Jochmans, Johan Neyts
A robust mouse model of HPIV-3 infection and efficacy of GS-441524 against virus-induced lung pathology. Nature communications 15 (1) (2024)
Dirk Jochmans, Cheng Liu, Kim Donckers, Antitsa Stoycheva, Sandro Boland, Sarah K Stevens, Chloe De Vita, Bert Vanmechelen, Piet Maes, Bettina Trüeb, Nadine Ebert, Volker Thiel, Steven De Jonghe, Laura Vangeel, Dorothée Bardiot, Andreas Jekle, Lawrence M Blatt, Leonid Beigelman, Julian A Symons, Pierre Raboisson, Patrick Chaltin, Arnaud Marchand, Johan Neyts, Jerome Deval, Koen Vandyck
The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir. mBio 14 (1) (2023)
Rana Abdelnabi, Dirk Jochmans, Kim Donckers, Bettina Trüeb, Nadine Ebert, Birgit Weynand, Volker Thiel, Johan Neyts
Nirmatrelvir-resistant SARS-CoV-2 is efficiently transmitted in female Syrian hamsters and retains partial susceptibility to treatment. Nature communications 14 (1) (2023)
Dirk Jochmans, Cheng Liu, Kim Donckers, Antitsa Stoycheva, Sandro Boland, Sarah K Stevens, Chloe De Vita, Bert Vanmechelen, Piet Maes, Bettina Trüeb, Nadine Ebert, Volker Thiel, Steven De Jonghe, Laura Vangeel, Dorothée Bardiot, Andreas Jekle, Lawrence M Blatt, Leonid Beigelman, Julian A Symons, Pierre Raboisson, Patrick Chaltin, Arnaud Marchand, Johan Neyts, Jerome Deval, Koen Vandyck
The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir. mBio 14 (1) (2023)
Dirk Jochmans, Cheng Liu, Kim Donckers, Antitsa Stoycheva, Sandro Boland, Sarah K Stevens, Chloe De Vita, Bert Vanmechelen, Piet Maes, Bettina Trüeb, Nadine Ebert, Volker Thiel, Steven De Jonghe, Laura Vangeel, Dorothée Bardiot, Andreas Jekle, Lawrence M Blatt, Leonid Beigelman, Julian A Symons, Pierre Raboisson, Patrick Chaltin, Arnaud Marchand, Johan Neyts, Jerome Deval, Koen Vandyck
The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir. mBio 14 (1) (2023)
Jordi Doijen, Koen Temmerman, Christel Van den Eynde, Annick Diels, Nick Van den Broeck, Michiel Van Gool, Inha Heo, Steffen Jaensch, Marleen Zwaagstra, Mayra Diosa Toro, Winston Chiu, Steven De Jonghe, Pieter Leyssen, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Lore Verschueren, Christophe Buyck, Frank J M van Kuppeveld, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Identification of Z-Tyr-Ala-CHN 2 , a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2. Microorganisms 11 (3) (2023)
Olaia Martí-Marí, Rana Abdelnabi, Dominique Schols, Johan Neyts, Maria-Jose Camarasa, Federico Gago, Ana San-Félix
Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates. International journal of molecular sciences 24 (4) (2023)
Olivia Goethals, Suzanne J F Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J Verschoor, Babs E Verstrepen, Zahra Fagrouch, J Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K McCracken, Gregory D Gromowski, Wiriya Rutvisuttinunt, Richard G Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier Nicolas de Lamballerie, Laurent Chatel-Chaix, Gregg N Milligan, David W C Beasley, Nigel Bourne, Alan D T Barrett, Arnaud Marchand, Tim H M Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf F W Bartenschlager, Willy M J M Bogers, Johan Neyts, Marnix Van Loock
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates. Nature (2023)
Olaia Martí-Marí, Rana Abdelnabi, Dominique Schols, Johan Neyts, Maria-Jose Camarasa, Federico Gago, Ana San-Félix
Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates. International journal of molecular sciences 24 (4) (2023)
Dirk Jochmans, Cheng Liu, Kim Donckers, Antitsa Stoycheva, Sandro Boland, Sarah K Stevens, Chloe De Vita, Bert Vanmechelen, Piet Maes, Bettina Trüeb, Nadine Ebert, Volker Thiel, Steven De Jonghe, Laura Vangeel, Dorothée Bardiot, Andreas Jekle, Lawrence M Blatt, Leonid Beigelman, Julian A Symons, Pierre Raboisson, Patrick Chaltin, Arnaud Marchand, Johan Neyts, Jerome Deval, Koen Vandyck
The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir. mBio (2023)
Xinyu Wang, Lisanne Terrie, Guanghui Wu, Els J M Van Damme, Lieven Thorrez, Anthony R Fooks, Ashley C Banyard, Dirk Jochmans, Johan Neyts
Urtica dioica Agglutinin Prevents Rabies Virus Infection in a Muscle Explant Model. Pharmaceutics 15 (5) (2023)
Olivia Goethals, Suzanne J F Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J Verschoor, Babs E Verstrepen, Zahra Fagrouch, J Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K McCracken, Gregory D Gromowski, Wiriya Rutvisuttinunt, Richard G Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier Nicolas de Lamballerie, Laurent Chatel-Chaix, Gregg N Milligan, David W C Beasley, Nigel Bourne, Alan D T Barrett, Arnaud Marchand, Tim H M Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf F W Bartenschlager, Willy M J M Bogers, Johan Neyts, Marnix Van Loock
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates. Nature 615 (7953) (2023)
Olivia Goethals, Suzanne J F Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J Verschoor, Babs E Verstrepen, Zahra Fagrouch, J Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K McCracken, Gregory D Gromowski, Wiriya Rutvisuttinunt, Richard G Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier Nicolas de Lamballerie, Laurent Chatel-Chaix, Gregg N Milligan, David W C Beasley, Nigel Bourne, Alan D T Barrett, Arnaud Marchand, Tim H M Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf F W Bartenschlager, Willy M J M Bogers, Johan Neyts, Marnix Van Loock
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates. Nature 615 (7953) (2023)
Xinyu Wang, Winston Chiu, Hugo Klaassen, Arnaud Marchand, Patrick Chaltin, Johan Neyts, Dirk Jochmans
A Robust Phenotypic High-Throughput Antiviral Assay for the Discovery of Rabies Virus Inhibitors. Viruses 15 (12) (2023)
Dirk Jochmans, Cheng Liu, Kim Donckers, Antitsa Stoycheva, Sandro Boland, Sarah K Stevens, Chloe De Vita, Bert Vanmechelen, Piet Maes, Bettina Trüeb, Nadine Ebert, Volker Thiel, Steven De Jonghe, Laura Vangeel, Dorothée Bardiot, Andreas Jekle, Lawrence M Blatt, Leonid Beigelman, Julian A Symons, Pierre Raboisson, Patrick Chaltin, Arnaud Marchand, Johan Neyts, Jerome Deval, Koen Vandyck
The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir. mBio 14 (1) (2023)
Jordi Doijen, Koen Temmerman, Christel Van den Eynde, Annick Diels, Nick Van den Broeck, Michiel Van Gool, Inha Heo, Steffen Jaensch, Marleen Zwaagstra, Mayra Diosa Toro, Winston Chiu, Steven De Jonghe, Pieter Leyssen, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Lore Verschueren, Christophe Buyck, Frank J M van Kuppeveld, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Identification of Z-Tyr-Ala-CHN 2 , a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2. Microorganisms 11 (3) (2023)
Jordi Doijen, Koen Temmerman, Christel Van den Eynde, Annick Diels, Nick Van den Broeck, Michiel Van Gool, Inha Heo, Steffen Jaensch, Marleen Zwaagstra, Mayra Diosa Toro, Winston Chiu, Steven De Jonghe, Pieter Leyssen, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Lore Verschueren, Christophe Buyck, Frank J M van Kuppeveld, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Identification of Z-Tyr-Ala-CHN 2 , a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2. Microorganisms 11 (3) (2023)
Olaia Martí-Marí, Rana Abdelnabi, Dominique Schols, Johan Neyts, Maria-Jose Camarasa, Federico Gago, Ana San-Félix
Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates. International journal of molecular sciences 24 (4) (2023)
Ngoc-Thao-Hien Le, Steven De Jonghe, Kristien Erven, Tom Vermeyen, Aliou Mamadou Balde, Wouter A Herrebout, Johan Neyts, Christophe Pannecouque, Luc Pieters, Emmy Tuenter
Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from Hymenocallis littoralis . Molecules (Basel, Switzerland) 28 (7) (2023)
Olivia Goethals, Suzanne J F Kaptein, Bart Kesteleyn, Jean-François Bonfanti, Liesbeth Van Wesenbeeck, Dorothée Bardiot, Ernst J Verschoor, Babs E Verstrepen, Zahra Fagrouch, J Robert Putnak, Dominik Kiemel, Oliver Ackaert, Roel Straetemans, Sophie Lachau-Durand, Peggy Geluykens, Marjolein Crabbe, Kim Thys, Bart Stoops, Oliver Lenz, Lotke Tambuyzer, Sandra De Meyer, Kai Dallmeier, Michael K McCracken, Gregory D Gromowski, Wiriya Rutvisuttinunt, Richard G Jarman, Nicos Karasavvas, Franck Touret, Gilles Querat, Xavier Nicolas de Lamballerie, Laurent Chatel-Chaix, Gregg N Milligan, David W C Beasley, Nigel Bourne, Alan D T Barrett, Arnaud Marchand, Tim H M Jonckers, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf F W Bartenschlager, Willy M J M Bogers, Johan Neyts, Marnix Van Loock
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates. Nature 615 (7953) (2023)
Tatiana M T Rezende, Gabriella Macera, Leo Heyndrickx, Johan Michiels, Sandra Coppens, Hendrik-Jan Thibaut, Kai Dallmeier, Marjan Van Esbroeck, Johan Neyts, Kevin K Ariën, Koen Bartholomeeusen
Validation of a Reporter Cell Line for Flavivirus Inhibition Assays. Microbiology spectrum (2023)
Xinyu Wang, Winston Chiu, Hugo Klaassen, Arnaud Marchand, Patrick Chaltin, Johan Neyts, Dirk Jochmans
A Robust Phenotypic High-Throughput Antiviral Assay for the Discovery of Rabies Virus Inhibitors. Viruses 15 (12) (2023)
Xinyu Wang, Winston Chiu, Hugo Klaassen, Arnaud Marchand, Patrick Chaltin, Johan Neyts, Dirk Jochmans
A Robust Phenotypic High-Throughput Antiviral Assay for the Discovery of Rabies Virus Inhibitors. Viruses 15 (12) (2023)
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. Viruses 15 (1) (2022)
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. Viruses 15 (1) (2022)
Shi-Yan Caroline Foo, Rana Abdelnabi, Laura Vangeel, Steven De Jonghe, Dirk Jochmans, Birgit Weynand, Johan Neyts
Ivermectin Does Not Protect against SARS-CoV-2 Infection in the Syrian Hamster Model. Microorganisms 10 (3) (2022)
Tine Tricot, Hendrik-Jan Thibaut, Kayvan Abbasi, Ruben Boon, Nicky Helsen, Manoj Kumar, Johan Neyts, Catherine Verfaillie
Metabolically Improved Stem Cell Derived Hepatocyte-Like Cells Support HBV Life Cycle and Are a Promising Tool for HBV Studies and Antiviral Drug Screenings. Biomedicines 10 (2) (2022)
Ji Ma, Robbert Boudewijns, Lorena Sanchez-Felipe, Niraj Mishra, Thomas Vercruysse, Dieudonné Buh Kum, Hendrik-Jan Thibaut, Johan Neyts, Kai Dallmeier
Comparing immunogenicity and protective efficacy of the yellow fever 17D vaccine in mice. Emerging microbes & infections 10 (1) (2022)
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. Viruses 15 (1) (2022)
Frauke Assmus, Jean-Sélim Driouich, Rana Abdelnabi, Laura Vangeel, Franck Touret, Ayorinde Adehin, Palang Chotsiri, Maxime Cochin, Caroline S Foo, Dirk Jochmans, Seungtaek Kim, Léa Luciani, Grégory Moureau, Soonju Park, Paul-Rémi Pétit, David Shum, Thanaporn Wattanakul, Birgit Weynand, Laurent Fraisse, Jean-Robert Ioset, Charles E Mowbray, Andrew Owen, Richard M Hoglund, Joel Tarning, Xavier de Lamballerie, Antoine Nougairède, Johan Neyts, Peter Sjö, Fanny Escudie, Ivan Scandale, Eric Chatelain
Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19. Microorganisms 10 (8) (2022)
Rana Abdelnabi, Caroline S Foo, Suzanne J F Kaptein, Robbert Boudewijns, Laura Vangeel, Steven De Jonghe, Dirk Jochmans, Birgit Weynand, Johan Neyts
A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection. Journal of virology 96 (16) (2022)
Nitesh K Gupta, Srinivasan Jayakumar, Wen-Chieh Huang, Pieter Leyssen, Johan Neyts, Sergey O Bachurin, Reuben Jih-Ru Hwu, Shwu-Chen Tsay
Bis(Benzofuran-1,3- N , N -heterocycle)s as Symmetric and Synthetic Drug Leads against Yellow Fever Virus. International journal of molecular sciences 23 (20) (2022)
César Muñoz-Fontela, Lina Widerspick, Randy A Albrecht, Martin Beer, Miles W Carroll, Emmie de Wit, Michael S. Diamond, William E Dowling, Simon G P Funnell, Adolfo García-Sastre, Nora M Gerhards, Rineke de Jong, Vincent J Munster, Johan Neyts, Stanley Perlman, Douglas S Reed, Juergen A Richt, Ximena Riveros-Balta, Chad J Roy, Francisco Javier Salguero, Michael Schotsaert, Lauren M Schwartz, Robert A Seder, Joaquim Segalés, Seshadri S Vasan, Ana María Henao-Restrepo, Dan H Barouch
Advances and gaps in SARS-CoV-2 infection models. PLoS pathogens 18 (1) (2022)
Thuc Nguyen Dan Do, Sandra Claes, Dominique Schols, Johan Neyts, Dirk Jochmans
SARS-CoV-2 Virion Infectivity and Cytokine Production in Primary Human Airway Epithelial Cells. Viruses 14 (5) (2022)
Annelies Wilder-Smith, Elizabeth Bailey Brickley, Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda Filho, Celina Maria Turchi Martelli, Tom Solomon, Bart C Jacobs, Carlos A Pardo-Villamizar, Lyda Osorio, Beatriz Parra, Suzannah Lant, Hugh John Willison, Sonja Leonhard, Lance Turtle, Maria Lúcia Brito Ferreira, Rafael Freitas de Oliveira Franca, Louis Lambrechts, Johan Neyts, Suzanne J F Kaptein, Rosanna Peeling, Deborah Boeras, James Logan, Helen Dolk, Iêda Maria Orioli, Andreas Neumayr, Trudie Lang, Bonny Baker, Eduardo Massad, Raman Preet
The legacy of ZikaPLAN: a transnational research consortium addressing Zika. Global health action 14 (sup1) (2022)
Arno Cuvry, Roberto Gozalbo-Rovira, Dufie Strubbe, Johan Neyts, Peter de Witte, Jésus Rodríguez-Díaz, Joana Rocha-Pereira
The Role of Histo-Blood Group Antigens and Microbiota in Human Norovirus Replication in Zebrafish Larvae. Microbiology spectrum (2022)
Dorothée Bardiot, Laura Vangeel, Mohamed Koukni, Philippe Arzel, Marleen Zwaagstra, Heyrhyoung Lyoo, Patrick Wanningen, Shamshad Ahmad, Linlin Zhang, Xinyuanyuan Sun, Adrien Delpal, Cecilia Eydoux, Jean-Claude Guillemot, Eveline Lescrinier, Hugo Klaassen, Pieter Leyssen, Dirk Jochmans, Karolien Castermans, Rolf Hilgenfeld, Colin Robinson, Etienne Decroly, Bruno Canard, Eric J Snijder, Martijn J van Hemert, Frank van Kuppeveld, Patrick Chaltin, Johan Neyts, Steven De Jonghe, Arnaud Marchand
Synthesis, Structure-Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication. Molecules (Basel, Switzerland) 27 (3) (2022)
Young-Jun Park, Anna De Marco, Tyler N Starr, Zhuoming Liu, Dora Pinto, Alexandra C Walls, Fabrizia Zatta, Samantha K Zepeda, John E Bowen, Kaitlin R Sprouse, Anshu Joshi, Martina Giurdanella, Barbara Guarino, Julia Noack, Rana Abdelnabi, Shi-Yan Caroline Foo, Laura E Rosen, Florian A Lempp, Fabio Benigni, Gyorgy Snell, Johan Neyts, Sean P J Whelan, Herbert W Virgin, Jesse D Bloom, Davide Corti, Matteo Samuele Pizzuto, David J Veesler
Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry. Science (New York, N.Y.) 375 (6579) (2022)
Young-Jun Park, Dora Pinto, Alexandra C Walls, Zhuoming Liu, Anna De Marco, Fabio Benigni, Fabrizia Zatta, Chiara Silacci-Fregni, Jessica Bassi, Kaitlin R Sprouse, Amin Addetia, John E Bowen, Cameron Stewart, Martina Giurdanella, Christian Saliba, Barbara Guarino, Michael Alexander Schmid, Nicholas M Franko, Jennifer K Logue, Ha V Dang, Kevin Hauser, Julia di Iulio, William Rivera, Gretja Schnell, Anushka Rajesh, Jiayi Zhou, Nisar Farhat, Hannah Kaiser, Martin Montiel-Ruiz, Julia Noack, Florian A Lempp, Javier Janer, Rana Abdelnabi, Piet Maes, Paolo Ferrari, Alessandro Ceschi, Olivier Giannini, Guilherme Dias de Melo, Lauriane Kergoat, Hervé Bourhy, Johan Neyts, Leah B Soriaga, Lisa A Purcell, Gyorgy Snell, Sean P J Whelan, Antonio Lanzavecchia, Herbert W Virgin, Luca Piccoli, Helen Y Chu, Matteo Samuele Pizzuto, Davide Corti, David J Veesler
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. Science (New York, N.Y.) 378 (6620) (2022)
Carmen Mirabelli, Nanci Santos-Ferreira, Merritt G Gillilland, Roberto J Cieza, Justin A Colacino, Jonathan Z Sexton, Johan Neyts, Stefan Taube, Joana Rocha-Pereira, Christiane E Wobus
Human Norovirus Efficiently Replicates in Differentiated 3D-Human Intestinal Enteroids. Journal of virology 96 (22) (2022)
Sapna Sharma, Thomas Vercruysse, Lorena Sanchez-Felipe, Winnie Kerstens, Madina Rasulova, Lindsey Bervoets, Carolien De Keyzer, Rana Abdelnabi, Shi-Yan Caroline Foo, Viktor Lemmens, Dominique Van Looveren, Piet Maes, Guy Baele, Birgit Weynand, Philippe Lemey, Johan Neyts, Hendrik-Jan Thibaut, Kai Dallmeier
Updated vaccine protects against SARS-CoV-2 variants including Omicron (B.1.1.529) and prevents transmission in hamsters. Nature communications 13 (1) (2022)
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdwijn, Dominique Schols, Peng Zhan, Xinyong Liu
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors. Molecules (Basel, Switzerland) 28 (1) (2022)
Craig Fenwick, Priscilla Turelli, Dongchun Ni, Laurent Perez, Kelvin Lau, Cécile Herate, Romain Marlin, Erica Lana, Céline Pellaton, Charlène Raclot, Line Esteves-Leuenberger, Jérémy Campos, Alex Farina, Flurin Fiscalini, Nathalie Bosquet, Francis Relouzat, Rana Abdelnabi, Shi-Yan Caroline Foo, Johan Neyts, Pieter Leyssen, Yves Lévy, Florence Pojer, Henning Stahlberg, Roger LeGrand, Didier Trono, Guiseppe Pantaleo
Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys. Nature microbiology 7 (9) (2022)
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdwijn, Dominique Schols, Peng Zhan, Xinyong Liu
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors. Molecules (Basel, Switzerland) 28 (1) (2022)
Reuben Jih-Ru Hwu, Animesh Roy, Shwu-Chen Tsay, Wen-Chieh Huang, Chun-Cheng Lin, Kuo Chu Hwang, Yu-Chen Hu, Fa-Kuen Shieh, Pieter Leyssen, Johan Neyts
Computer-Aided Design and Synthesis of (Functionalized quinazoline)-(α-substituted coumarin)-arylsulfonate Conjugates against Chikungunya Virus. International journal of molecular sciences 23 (14) (2022)
Jun Siong Low, Josipa Jerak, M Alejandra Tortorici, Matthew McCallum, Dora Pinto, Antonino Cassotta, Mathilde Foglierini, Federico Mele, Rana Abdelnabi, Birgit Weynand, Julia Noack, Martin Montiel-Ruiz, Siro Bianchi, Fabio Benigni, Nicole Sprugasci, Anshu Joshi, John E Bowen, Cameron Stewart, Megi Rexhepaj, Alexandra C Walls, David Jarrossay, Diego Morone, Philipp Paparoditis, Christian Garzoni, Paolo Ferrari, Alessandro Ceschi, Johan Neyts, Lisa A Purcell, Gyorgy Snell, Davide Corti, Antonio Lanzavecchia, David J Veesler, Federica Sallusto
ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies. Science (New York, N.Y.) 377 (6607) (2022)
Andrea Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis, Maria Kuzikov, Oliver Keminer, Markus Wolf, Bernhard Ellinger, Francesca Esposito, Angela Corona, Enzo Tramontano, Candida Manelfi, Katja Herzog, Dirk Jochmans, Steven De Jonghe, Winston Chiu, Thibault Francken, Joost Schepers, Caroline Collard, Kayvan Abbasi, Carsten Claussen, Vincenzo Summa, Andrea R Beccari, Johan Neyts, Philip Gribbon, Pieter Leyssen
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort. Scientific data 9 (1) (2022)
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. Viruses 15 (1) (2022)
Maxime Cochin, Léa Luciani, Franck Touret, Jean-Sélim Driouich, Paul-Rémi Petit, Grégory Moureau, Cécile Baronti, Caroline Laprie, Laurence Thirion, Piet Maes, Robbert Boudewijns, Johan Neyts, Xavier de Lamballerie, Antoine Nougairède
The SARS-CoV-2 Alpha variant exhibits comparable fitness to the D614G strain in a Syrian hamster model. Communications biology 5 (1) (2022)
Gilda Giancotti, Giulio Nannetti, Gilda Padalino, Martina Landini, Nanci Santos-Ferreira, Jana Van Dycke, Valentina Naccarato, Usheer Patel, Romano Silvestri, Johan Neyts, Roberto Gozalbo-Rovira, Jésus Rodríguez-Díaz, Joana Rocha-Pereira, Andrea Brancale, Salvatore Ferla, Marcella Bassetto
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase. Viruses 15 (1) (2022)
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdwijn, Dominique Schols, Peng Zhan, Xinyong Liu
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors. Molecules (Basel, Switzerland) 28 (1) (2022)
Rana Abdelnabi, Shi-Yan Caroline Foo, Dirk Jochmans, Laura Vangeel, Steven De Jonghe, Patrick Augustijns, Raf Mols, Birgit Weynand, Thanaporn Wattanakul, Richard M Hoglund, Joel Tarning, Charles E Mowbray, Peter Sjö, Fanny Escudie, Ivan Scandale, Eric Chatelain, Johan Neyts
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern. Nature communications 13 (1) (2022)
M Alejandra Tortorici, Nadine Czudnochowski, Tyler N Starr, Roberta Marzi, Alexandra C Walls, Fabrizia Zatta, John E Bowen, Stefano Jaconi, Julia Di Iulio, Zhaoqian Wang, Anna De Marco, Samantha K Zepeda, Dora Pinto, Zhuoming Liu, Martina Beltramello, Istvan Bartha, Michael P Housley, Florian A Lempp, Laura E Rosen, Exequiel Dellota, Hannah Kaiser, Martin Montiel-Ruiz, Jiayi Zhou, Amin Addetia, Barbara Guarino, Katja Culap, Nicole Sprugasci, Christian Saliba, Eneida Vetti, Isabella Giacchetto-Sasselli, Chiara Silacci Fregni, Rana Abdelnabi, Shi-Yan Caroline Foo, Colin Havenar-Daughton, Michael Alexander Schmid, Fabio Benigni, Elisabetta Cameroni, Johan Neyts, Amalio Telenti, Herbert W Virgin, Sean P J Whelan, Gyorgy Snell, Jesse D Bloom, Davide Corti, David J Veesler, Matteo Samuele Pizzuto
Broad sarbecovirus neutralization by a human monoclonal antibody. Nature 597 (7874) (2021)
Tyler N Starr, Nadine Czudnochowski, Zhuoming Liu, Fabrizia Zatta, Young-Jun Park, Amin Addetia, Dora Pinto, Martina Beltramello, Patrick Hernandez, Allison J Greaney, Roberta Marzi, William G Glass, Ivy Zhang, Adam S Dingens, John E Bowen, M Alejandra Tortorici, Alexandra C Walls, Jason A Wojcechowskyj, Anna De Marco, Laura E Rosen, Jiayi Zhou, Martin Montiel-Ruiz, Hannah Kaiser, Josh R Dillen, Heather Tucker, Jessica Bassi, Chiara Silacci-Fregni, Michael P Housley, Julia di Iulio, Gloria Lombardo, Maria Agostini, Nicole Sprugasci, Katja Culap, Stefano Jaconi, Marcel Meury, Exequiel Dellota, Rana Abdelnabi, Shi-Yan Caroline Foo, Elisabetta Cameroni, Spencer Stumpf, Tristan I Croll, Jay C Nix, Colin Havenar-Daughton, Luca Piccoli, Fabio Benigni, Johan Neyts, Amalio Telenti, Florian A Lempp, Matteo Samuele Pizzuto, John D Chodera, Christy M Hebner, Herbert W Virgin, Sean P J Whelan, David J Veesler, Davide Corti, Jesse D Bloom, Gyorgy Snell
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape. Nature 597 (7874) (2021)
Nanci Santos-Ferreira, Jana Van Dycke, Johan Neyts, Joana Rocha-Pereira
Current and Future Antiviral Strategies to Tackle Gastrointestinal Viral Infections. Microorganisms 9 (8) (2021)
Bert Schepens, Loes van Schie, Wim Nerinckx, Kenny Roose, Wander Van Breedam, Daria Fijalkowska, Simon Devos, Wannes Weyts, Sieglinde De Cae, Sandrine Vanmarcke, Chiara Lonigro, Hannah Eeckhaut, Dries Van Herpe, Jimmy Borloo, Ana Filipa Oliveira, João Paulo Portela Catani, Sarah Creytens, Dorien De Vlieger, Gitte Michielsen, Jackeline Cecilia Zavala Marchan, George D Moschonas, Iebe Rossey, Koen Sedeyn, Annelies Van Hecke, Xin Zhang, Lana Langendries, Sofie Jacobs, Sebastiaan Ter Horst, Laura Seldeslachts, Laurens Liesenborghs, Robbert Boudewijns, Hendrik-Jan Thibaut, Kai Dallmeier, Greetje Vande Velde, Birgit Weynand, Julius Beer, Daniel Schnepf, Annette Ohnemus, Isabel Remory, Shi-Yan Caroline Foo, Rana Abdelnabi, Piet Maes, Suzanne J F Kaptein, Joana Rocha-Pereira, Dirk Jochmans, Leen Delang, Frank Peelman, Peter Staeheli, Martin Schwemmle, Nick Devoogdt, Dominique Tersago, Massimiliano Germani, James T Heads, Alistair J Henry, Andrew Popplewell, Mark Ellis, Kevin Brady, Alison Turner, Bruno Dombrecht, Catelijne Stortelers, Johan Neyts, Nico Callewaert, Xavier Saelens
An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models. Science translational medicine 13 (621) (2021)
Lore Vanderbeke, P Van Mol, Y Van Herck, Frederik De Smet, S Humblet-Baron, Kimberly Martinod, A Antoranz, Ingrid Arijs, B Boeckx, F M Bosisio, M Casaer, Dieter Frans Dauwe, W De Wever, C Dooms, Erwin Dreesen, Annelies Emmaneel, J Filtjens, M Gouwy, Jan Gunst, G Hermans, Sander Jansen, K Lagrou, Adrian Liston, N Lorent, P Meersseman, Toine Mercier, Johan Neyts, J Odent, D Panovska, P A Penttila, E Pollet, Mieke Gouwy, Junbin Qian, Katrien L A Quintelier, Jeroen Raes, S Rex, Yvan Saeys, J Sprooten, S Tejpar, D Testelmans, Karin Thevissen, T Van Buyten, Jessica Vandenhaute, Sofie Van Gassen, L C Velásquez Pereira, Robin Vos, B Weynand, A Wilmer, J Yserbyt, Abhishek Dinkarnath Garg, Patrick Matthys, C Wouters, Diether Lambrechts, Els Wauters, J Wauters
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity. Nature communications 12 (1) (2021)
Jana Van Dycke, Wenhao Dai, Zoe Stylianidou, Jian Li, Arno Cuvry, Emma Roux, Bingqian Li, Jasper Rymenants, Lindsey Bervoets, Peter A M de Witte, Hong Liu, Johan Neyts, Joana Rocha-Pereira
A Novel Class of Norovirus Inhibitors Targeting the Viral Protease with Potent Antiviral Activity In Vitro and In Vivo. Viruses 13 (9) (2021)
Kai Dallmeier, Geert Meyfroidt, Johan Neyts
COVID-19 and the intensive care unit: vaccines to the rescue. Intensive care medicine 47 (7) (2021)
Veronica Lloréns-Rico, Ann C Gregory, Johan Van Weyenbergh, Sander Jansen, Tina Van Buyten, Junbin Qian, Marcos Braz, Soraya Maria Menezes, Pierre Van Mol, Lore Vanderbeke, Christophe Dooms, Jan Gunst, Greet Hermans, Philippe Meersseman, null null, Els Wauters, Johan Neyts, Diether Lambrechts, Joost Wauters, Jeroen Raes
Clinical practices underlie COVID-19 patient respiratory microbiome composition and its interactions with the host. Nature communications 12 (1) (2021)
Fabien Aubry, Sofie Jacobs, Maïlis Darmuzey, Sébastian Lequime, Leen Delang, Albin Fontaine, Natapong Jupatanakul, Elliott F Miot, Stéphanie Dabo, Caroline Manet, Xavier Montagutelli, Artem Baidaliuk, Fabiana Gámbaro, Etienne Simon-Loriere, Maxime Gilsoul, Claudia M Romero-Vivas, Van-Mai Cao-Lormeau, Richard G Jarman, Cheikh T Diagne, Oumar Faye, Ousmane Faye, Amadou A Sall, Johan Neyts, Laurent Nguyen, Suzanne J F Kaptein, Louis Lambrechts
Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains. Nature communications 12 (1) (2021)
Suzanne J F Kaptein, Olivia Goethals, Dominik Kiemel, Arnaud Marchand, Bart Kesteleyn, Jean-François Bonfanti, Dorothée Bardiot, Bart Stoops, Tim H M Jonckers, Kai Dallmeier, Peggy Geluykens, Kim Thys, Marjolein Crabbe, Laurent Chatel-Chaix, Max Münster, Gilles Querat, Franck Touret, Xavier de Lamballerie, Pierre Raboisson, Kenny Simmen, Patrick Chaltin, Ralf F W Bartenschlager, Marnix Van Loock, Johan Neyts
A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. Nature 598 (7881) (2021)
Steven R Bryden, Marieke Pingen, Daniella A Lefteri, Janne Miltenburg, Leen Delang, Sofie Jacobs, Rana Abdelnabi, Johan Neyts, Emilie Pondeville, Jack Major, Marietta Müller, Henna Khalid, Andrew Tuplin, Margus Varjak, Andres Merits, Julia M Edgar, Gerard J Graham, Kave Shams, Clive S McKimmie
Pan-viral protection against arboviruses by activating skin macrophages at the inoculation site. Science translational medicine 12 (527) (2021)
Jana Van Dycke, Michela Puxeddu, Giuseppe La Regina, Eloise Mastrangelo, Delia Tarantino, Jasper Rymenants, Jessica Sebastiani, Marianna Nalli, Jelle Matthijnssens, Johan Neyts, Romano Silvestri, Joana Rocha-Pereira
Discovery of a Novel Class of Norovirus Inhibitors with High Barrier of Resistance. Pharmaceuticals (Basel, Switzerland) 14 (10) (2021)
Lana Langendries, Rana Abdelnabi, Johan Neyts, Leen Delang
Repurposing Drugs for Mayaro Virus: Identification of EIDD-1931, Favipiravir and Suramin as Mayaro Virus Inhibitors. Microorganisms 9 (4) (2021)
Sander Jansen, Enisa Smlatic, Daniëlle Copmans, Sarah Debaveye, Frédéric Tangy, Pierre-Olivier Vidalain, Johan Neyts, Kai Dallmeier
Identification of host factors binding to dengue and Zika virus subgenomic RNA by efficient yeast three-hybrid screens of the human ORFeome. RNA biology 18 (5) (2021)
Salvatore Ferla, Carmine Varricchio, William Knight, Pui Kei Ho, Fabiana Saporito, Beatrice Tropea, Giulio Fagan, Ben Matthew Flude, Federica Bevilacqua, Nanci Santos-Ferreira, Jana Van Dycke, Johan Neyts, Andrea Brancale, Joana Rocha-Pereira, Marcella Bassetto
Structure-Activity Relationship Studies on Novel Antiviral Agents for Norovirus Infections. Microorganisms 9 (9) (2021)
Suzanne J F Kaptein, Sofie Jacobs, Lana Langendries, Laura Seldeslachts, Sebastiaan Ter Horst, Laurens Liesenborghs, Bart Hens, Valentijn Vergote, Elisabeth Heylen, Karine Barthelemy, Elke Maas, Carolien De Keyzer, Lindsey Bervoets, Jasper Rymenants, Tina Van Buyten, Xin Zhang, Rana Abdelnabi, Juanita Pang, Rachel Williams, Hendrik-Jan Thibaut, Kai Dallmeier, Robbert Boudewijns, Jens Wouters, Patrick Augustijns, Nick Verougstraete, Christopher J Cawthorne, Judith Breuer, Caroline Solas, Birgit Weynand, Pieter Annaert, Isabel Spriet, Greetje Vande Velde, Johan Neyts, Joana Rocha-Pereira, Leen Delang
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity. Proceedings of the National Academy of Sciences of the United States of America 117 (43) (2020)
Lisa Bauer, Roberto Manganaro, Birgit Zonsics, Daniel L Hurdiss, Marleen Zwaagstra, Tim Donselaar, Naemi G E Welter, Regina G D M van Kleef, Moira Lorenzo Lopez, Federica Bevilacqua, Thamidur Raman, Salvatore Ferla, Marcella Bassetto, Johan Neyts, Jeroen R P M Strating, Remco H S Westerink, Andrea Brancale, Frank J M van Kuppeveld
Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C. PLoS biology 18 (11) (2020)
Dieudonné Buh Kum, Niraj Mishra, Bram Vrancken, Hendrik-Jan Thibaut, Annelies Wilder-Smith, Philippe Lemey, Johan Neyts, Kai Dallmeier
Limited evolution of the yellow fever virus 17d in a mouse infection model. Emerging microbes & infections 8 (1) (2020)
M Alejandra Tortorici, Martina Beltramello, Florian A Lempp, Dora Pinto, Ha V Dang, Laura E Rosen, Matthew McCallum, John E Bowen, Andrea Minola, Stefano Jaconi, Fabrizia Zatta, Anna De Marco, Barbara Guarino, Siro Bianchi, Elvin J Lauron, Heather Tucker, Jiayi Zhou, Alessia Peter, Colin Havenar-Daughton, Jason A Wojcechowskyj, James Brett Case, Rita E Chen, Hannah Kaiser, Martin Montiel-Ruiz, Marcel Meury, Nadine Czudnochowski, Philip Lsm Gordts, Josh R Dillen, Cindy Ng, Nicole Sprugasci, Katja Culap, Fabio Benigni, Rana Abdelnabi, Shi-Yan Caroline Foo, Michael Alexander Schmid, Elisabetta Cameroni, Agostino Riva, Arianna Gabrieli, Massimo Galli, Matteo Samuele Pizzuto, Johan Neyts, Michael S. Diamond, Herbert W Virgin, Gyorgy Snell, Davide Corti, Katja Fink, David J Veesler
Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms. Science (New York, N.Y.) 370 (6519) (2020)
Dieudonné Buh Kum, Robbert Boudewijns, Ji Ma, Niraj Mishra, Dominique Schols, Johan Neyts, Kai Dallmeier
A chimeric yellow fever-Zika virus vaccine candidate fully protects against yellow fever virus infection in mice. Emerging microbes & infections 9 (1) (2020)
Mohamed Fares, Patrick M McCosker, Muhammad A Alsherbiny, Anthony C Willis, Timothy Clark, Johan Neyts, Dirk Jochmans, Paul A Keller
Regioselective convergent synthesis of 2-arylidene thiazolo[3,2- a ]pyrimidines as potential anti-chikungunya agents. RSC advances 10 (9) (2020)
Annelies Wilder-Smith, Raman Preet, Elizabeth Bailey Brickley, Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda Filho, Celina Maria Turchi Martelli, Thália Velho Barreto de Araújo, Ulisses Ramos Montarroyos, Maria Elisabeth Moreira, Marília Dalva Turchi, Tom Solomon, Bart C Jacobs, Carlos Pardo Villamizar, Lyda Osorio, Ana Maria Bispo de Filipps, Johan Neyts, Suzanne J F Kaptein, Ralph Huits, Kevin K Ariën, Hugh John Willison, Julia M Edgar, Susan C Barnett, Rosanna Peeling, Debi Boeras, Maria G Guzman, Aravinda M de Silva, Andrew K Falconar, Claudia Romero-Vivas, Michael W Gaunt, Alessandro Sette, Daniela Weiskopf, Louis Lambrechts, Helen Dolk, Joan K Morris, Iêda Maria Orioli, Kathleen M O'Reilly, Laith Yakob, Joacim Rocklöv, Cristiane Soares, Maria Lúcia Brito Ferreira, Rafael Freitas de Oliveira Franca, Alexander Roberto Precioso, James Logan, Trudie Lang, Nina Jamieson, Eduardo Massad
ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas. Global health action 12 (1) (2020)
Sapna Sharma, Michael Alexander Schmid, Lorena Sanchez-Felipe, Jana Grenelle, Suzanne J F Kaptein, Lotte Coelmont, Johan Neyts, Kai Dallmeier
Small-molecule inhibitors of TBK1 serve as an adjuvant for a plasmid-launched live-attenuated yellow fever vaccine. Human vaccines & immunotherapeutics 16 (9) (2020)
Robbert Boudewijns, Hendrik-Jan Thibaut, Suzanne J F Kaptein, Rong Li, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Carolien De Keyzer, Lindsey Bervoets, Sapna Sharma, Laurens Liesenborghs, Ji Ma, Sander Jansen, Dominique Van Looveren, Thomas Vercruysse, Xinyu Wang, Dirk Jochmans, Erik Martens, Kenny Roose, Dorien De Vlieger, Bert Schepens, Tina Van Buyten, Sofie Jacobs, Yanan Liu, Joan Martí-Carreras, Bert Vanmechelen, Tony Wawina-Bokalanga, Leen Delang, Joana Rocha-Pereira, Lotte Coelmont, Winston Chiu, Pieter Leyssen, Elisabeth Heylen, Dominique Schols, Lanjiao Wang, Lila Close, Jelle Matthijnssens, Marc Van Ranst, Veerle Compernolle, Georg Schramm, Koen Van Laere, Xavier Saelens, Nico Callewaert, Ghislain Opdenakker, Piet Maes, Birgit Weynand, Christopher J Cawthorne, Greetje Vande Velde, Zhongde Wang, Johan Neyts, Kai Dallmeier
STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters. Nature communications 11 (1) (2020)
Simone Musiu, Yunierkis Perez Castillo, Alexandra Muigg, Gerhard Pürstinger, Pieter Leyssen, Mathy Froeyen, Johan Neyts, Jan Paeshuyse
Quinolinecarboxamides Inhibit the Replication of the Bovine Viral Diarrhea Virus by Targeting a Hot Spot for the Inhibition of Pestivirus Replication in the RNA-Dependent RNA Polymerase. Molecules (Basel, Switzerland) 25 (6) (2020)
Niraj Mishra, Robbert Boudewijns, Michael Alexander Schmid, Rafael Elias Marques, Sapna Sharma, Johan Neyts, Kai Dallmeier
A Chimeric Japanese Encephalitis Vaccine Protects against Lethal Yellow Fever Virus Infection without Inducing Neutralizing Antibodies. mBio 11 (2) (2020)
Lorena Sanchez-Felipe, Thomas Vercruysse, Sapna Sharma, Ji Ma, Viktor Lemmens, Dominique Van Looveren, Mahadesh Prasad Arkalagud Javarappa, Robbert Boudewijns, Bert Malengier-Devlies, Laurens Liesenborghs, Suzanne J F Kaptein, Carolien De Keyzer, Lindsey Bervoets, Sarah Debaveye, Madina Rasulova, Laura Seldeslachts, Li-Hsin Li, Sander Jansen, Michael Bright Yakass, Babs E Verstrepen, Kinga P Böszörményi, Gwendoline Kiemenyi-Kayere, Nikki van Driel, Osbourne Quaye, Xin Zhang, Sebastiaan Ter Horst, Niraj Mishra, Ward Deboutte, Jelle Matthijnssens, Lotte Coelmont, Corinne Vandermeulen, Elisabeth Heylen, Valentijn Vergote, Dominique Schols, Zhongde Wang, Willy M J M Bogers, Thijs Kuiken, Ernst J Verschoor, Christopher J Cawthorne, Koen Van Laere, Ghislain Opdenakker, Greetje Vande Velde, Birgit Weynand, Dirk E Teuwen, Patrick Matthys, Johan Neyts, Hendrik-Jan Thibaut, Kai Dallmeier
A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate. Nature 590 (7845) (2020)
Sofie Jacobs, Leen Delang, Eric Verbeken, Johan Neyts, Suzanne J F Kaptein
A Viral Polymerase Inhibitor Reduces Zika Virus Replication in the Reproductive Organs of Male Mice. International journal of molecular sciences 20 (9) (2019)
Sebastiaan Ter Horst, Nádia Conceição-Neto, Johan Neyts, Joana Rocha-Pereira
Structural and functional similarities in bunyaviruses: Perspectives for pan-bunya antivirals. Reviews in medical virology 29 (3) (2019)
Nicholas Hernandez, Giorgia Bucciol, Leen Moens, Jérémie Le Pen, Mohammad Shahrooei, Ekaterini Simões Goudouris, Afshin Shirkani, Majid Changi-Ashtiani, Hassan Rokni-Zadeh, Esra Hazar Sayar, Ismail Reisli, Alain Lefevre-Utile, Dick Zijlmans, Andrea Jurado, Ruben Pholien, Scott B Drutman, Serkan Belkaya, Aurélie Cobat, Robbert Boudewijns, Dirk Jochmans, Johan Neyts, Yoann Seeleuthner, Lazaro Lorenzo-Diaz, Chibuzo Enemchukwu, Ian Tietjen, Hans-Heinrich Hoffmann, Mana Momenilandi, Laura Pöyhönen, Marilda M Siqueira, Sheila M Barbosa de Lima, Denise C de Souza Matos, Akira Homma, Maria de Lourdes S Maia, Tamiris Azamor da Costa Barros, Patricia Mouta Nunes de Oliveira, Emersom Ciclini Mesquita, Rik Gijsbers, Shen-Ying Zhang, Stephen J Seligman, Laurent Abel, Paul Hertzog, Nico Marr, Reinaldo de Menezes Martins, Isabelle Meyts, Qian Zhang, Margaret R MacDonald, Charles M Rice, Jean Laurent Casanova, Emmanuelle Jouanguy, Xavier Bossuyt
Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines. The Journal of experimental medicine 216 (9) (2019)
Liang Sun, Hyun-Wook Lee, Hendrik-Jan Thibaut, Kristina Lanko, Eva Rivero-Buceta, Carol Bator, Belen Martinez-Gualda, Kai Dallmeier, Leen Delang, Pieter Leyssen, Federico Gago, Ana San-Félix, Susan L Hafenstein, Carmen Mirabelli, Johan Neyts
Viral engagement with host receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid. PLoS pathogens 15 (5) (2019)
Rana Abdelnabi, James A Geraets, Yipeng Ma, Carmen Mirabelli, Justin W Flatt, Aušra Domanska, Leen Delang, Dirk Jochmans, Timiri Ajay Kumar, Venkatesan Jayaprakash, Barij Nayan Sinha, Pieter Leyssen, Sarah Jane Butcher, Johan Neyts
A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses. PLoS biology 17 (6) (2019)
Liang Sun, Aloys Tijsma, Carmen Mirabelli, Jim Baggen, Maryam Wahedi, David Franco, Armando De Palma, Pieter Leyssen, Erik Verbeken, Frank J M van Kuppeveld, Johan Neyts, Hendrik-Jan Thibaut
Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence. Emerging microbes & infections 8 (1) (2019)
Jana Van Dycke, Annelii Ny, Nádia Conceição-Neto, Jan Maes, Myra Hosmillo, Arno Cuvry, Ian Goodfellow, Tatiane C Nogueira, Erik Verbeken, Jelle Matthijnssens, Peter A M de Witte, Johan Neyts, Joana Rocha-Pereira
A robust human norovirus replication model in zebrafish larvae. PLoS pathogens 15 (9) (2019)
Yannick Debing, Niraj Mishra, Erik Verbeken, Kaat Ramaekers, Kai Dallmeier, Johan Neyts
A rat model for hepatitis E virus. Disease models & mechanisms 9 (10) (2016)

Johan Neyts.css-eqlu8i{font-size:small;padding-left:4px;} (J Neyts)

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Johan Neyts (J Neyts)