Steven De Jonghe (Steven de Jonghe)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 48

Top Topics

Structure Activity Relationship

Top Venues

Molecules (Basel, Switzerland)

Cancer immunology, immunotherapy : CII

Journal of medicinal chemistry

Organic letters

This page only lists publications with an associated author ORCID identifier.

Publications

Libao Liu, Laurie Rangan, Nathan Vanalken, Qianqian Kong, Susan M Schlenner, Steven De Jonghe, Dominique Schols, Tom Van Loy
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells. Cancer immunology, immunotherapy : CII 73 (1) (2024)
Tom Grisez, Nitha Panikkassery Ravi, Matheus Froeyen, Dominique Schols, Luc Van Meervelt, Steven De Jonghe, Wim Dehaen
Synthesis of a 3,7-Disubstituted Isothiazolo[4,3- b ]pyridine as a Potential Inhibitor of Cyclin G-Associated Kinase. Molecules (Basel, Switzerland) 29 (5) (2024)
Libao Liu, Laurie Rangan, Nathan Vanalken, Qianqian Kong, Susan M Schlenner, Steven De Jonghe, Dominique Schols, Tom Van Loy
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells. Cancer immunology, immunotherapy : CII 73 (1) (2024)
Yulia Ivanova, Sander Spittaels, Ling-Jie Gao, Dominique Schols, Luc Van Meervelt, Matheus Froeyen, Wim Dehaen, Steven De Jonghe
Synthesis and evaluation of isothiazolo[4,5- b ]pyridines as cyclin G-associated kinase (GAK) inhibitors. Organic & biomolecular chemistry (2024)
Libao Liu, Laurie Rangan, Nathan Vanalken, Qianqian Kong, Susan M Schlenner, Steven De Jonghe, Dominique Schols, Tom Van Loy
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells. Cancer immunology, immunotherapy : CII 73 (1) (2024)
Libao Liu, Laurie Rangan, Nathan Vanalken, Qianqian Kong, Susan M Schlenner, Steven De Jonghe, Dominique Schols, Tom Van Loy
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells. Cancer immunology, immunotherapy : CII 73 (1) (2024)
Tom Grisez, Nitha Panikkassery Ravi, Matheus Froeyen, Dominique Schols, Luc Van Meervelt, Steven De Jonghe, Wim Dehaen
Synthesis of a 3,7-Disubstituted Isothiazolo[4,3- b ]pyridine as a Potential Inhibitor of Cyclin G-Associated Kinase. Molecules (Basel, Switzerland) 29 (5) (2024)
Libao Liu, Laurie Rangan, Nathan Vanalken, Qianqian Kong, Susan M Schlenner, Steven De Jonghe, Dominique Schols, Tom Van Loy
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells. Cancer immunology, immunotherapy : CII 73 (1) (2024)
Tom Grisez, Nitha Panikkassery Ravi, Matheus Froeyen, Dominique Schols, Luc Van Meervelt, Steven De Jonghe, Wim Dehaen
Synthesis of a 3,7-Disubstituted Isothiazolo[4,3- b ]pyridine as a Potential Inhibitor of Cyclin G-Associated Kinase. Molecules (Basel, Switzerland) 29 (5) (2024)
Libao Liu, Laurie Rangan, Nathan Vanalken, Qianqian Kong, Susan M Schlenner, Steven De Jonghe, Dominique Schols, Tom Van Loy
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells. Cancer immunology, immunotherapy : CII 73 (1) (2024)
Libao Liu, Laurie Rangan, Nathan Vanalken, Qianqian Kong, Susan M Schlenner, Steven De Jonghe, Dominique Schols, Tom Van Loy
Development of a cellular model to study CCR8 signaling in tumor-infiltrating regulatory T cells. Cancer immunology, immunotherapy : CII 73 (1) (2024)
Neng Wang, Hang Wang, Lin-Xi Wan, Xiao-Huan Li, Xian-Li Zhou, Jia-Hong Li, Steven De Jonghe, Dominique Schols, Jin-Bu Xu, Feng Gao
Visible-Light-Promoted Tandem Thiol-Ene Click Reaction/Transannular Cyclization and Regioselective Cyclopropane Ring-Opening to Construct Sulfur-Containing Euphorbia Diterpenes. Organic letters (2023)
Max Van Hoof, Sandra Claes, Katrijn Boon, Tom Van Loy, Dominique Schols, Wim Dehaen, Steven De Jonghe
Exploration of Pyrido[3,4- d ]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2. Molecules (Basel, Switzerland) 28 (5) (2023)
Jordi Doijen, Koen Temmerman, Christel Van den Eynde, Annick Diels, Nick Van den Broeck, Michiel Van Gool, Inha Heo, Steffen Jaensch, Marleen Zwaagstra, Mayra Diosa Toro, Winston Chiu, Steven De Jonghe, Pieter Leyssen, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Lore Verschueren, Christophe Buyck, Frank J M van Kuppeveld, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Identification of Z-Tyr-Ala-CHN 2 , a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2. Microorganisms 11 (3) (2023)
Max Van Hoof, Sandra Claes, Katrijn Boon, Tom Van Loy, Dominique Schols, Wim Dehaen, Steven De Jonghe
Exploration of Pyrido[3,4- d ]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2. Molecules (Basel, Switzerland) 28 (5) (2023)
Jordi Doijen, Koen Temmerman, Christel Van den Eynde, Annick Diels, Nick Van den Broeck, Michiel Van Gool, Inha Heo, Steffen Jaensch, Marleen Zwaagstra, Mayra Diosa Toro, Winston Chiu, Steven De Jonghe, Pieter Leyssen, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Lore Verschueren, Christophe Buyck, Frank J M van Kuppeveld, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Identification of Z-Tyr-Ala-CHN 2 , a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2. Microorganisms 11 (3) (2023)
Jordi Doijen, Koen Temmerman, Christel Van den Eynde, Annick Diels, Nick Van den Broeck, Michiel Van Gool, Inha Heo, Steffen Jaensch, Marleen Zwaagstra, Mayra Diosa Toro, Winston Chiu, Steven De Jonghe, Pieter Leyssen, Denisa Bojkova, Sandra Ciesek, Jindrich Cinatl, Lore Verschueren, Christophe Buyck, Frank J M van Kuppeveld, Johan Neyts, Marnix Van Loock, Ellen Van Damme
Identification of Z-Tyr-Ala-CHN 2 , a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2. Microorganisms 11 (3) (2023)
Ngoc-Thao-Hien Le, Steven De Jonghe, Kristien Erven, Tom Vermeyen, Aliou Mamadou Balde, Wouter A Herrebout, Johan Neyts, Christophe Pannecouque, Luc Pieters, Emmy Tuenter
Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from Hymenocallis littoralis . Molecules (Basel, Switzerland) 28 (7) (2023)
Neng Wang, Hang Wang, Lin-Xi Wan, Xiao-Huan Li, Xian-Li Zhou, Jia-Hong Li, Steven De Jonghe, Dominique Schols, Jin-Bu Xu, Feng Gao
Visible-Light-Promoted Tandem Thiol-Ene Click Reaction/Transannular Cyclization and Regioselective Cyclopropane Ring-Opening to Construct Sulfur-Containing Euphorbia Diterpenes. Organic letters 25 (4) (2023)
Max Van Hoof, Sandra Claes, Katrijn Boon, Tom Van Loy, Dominique Schols, Wim Dehaen, Steven De Jonghe
Exploration of Pyrido[3,4- d ]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2. Molecules (Basel, Switzerland) 28 (5) (2023)
Max Van Hoof, Sandra Claes, Katrijn Boon, Tom Van Loy, Dominique Schols, Wim Dehaen, Steven De Jonghe
Exploration of Pyrido[3,4- d ]pyrimidines as Antagonists of the Human Chemokine Receptor CXCR2. Molecules (Basel, Switzerland) 28 (5) (2023)
Neng Wang, Hang Wang, Lin-Xi Wan, Xiao-Huan Li, Xian-Li Zhou, Jia-Hong Li, Steven De Jonghe, Dominique Schols, Jin-Bu Xu, Feng Gao
Visible-Light-Promoted Tandem Thiol-Ene Click Reaction/Transannular Cyclization and Regioselective Cyclopropane Ring-Opening to Construct Sulfur-Containing Euphorbia Diterpenes. Organic letters 25 (4) (2023)
Maria Karelou, Dionysis Kampasis, Amalia D Kalampaliki, Leentje Persoons, Andreas Krämer, Dominique Schols, Stefan Knapp, Steven De Jonghe, Ioannis K Kostakis
Synthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3 H )-Ones with Antiproliferative Activities. Molecules (Basel, Switzerland) 28 (23) (2023)
Neng Wang, Hang Wang, Lin-Xi Wan, Xiao-Huan Li, Xian-Li Zhou, Jia-Hong Li, Steven De Jonghe, Dominique Schols, Jin-Bu Xu, Feng Gao
Visible-Light-Promoted Tandem Thiol-Ene Click Reaction/Transannular Cyclization and Regioselective Cyclopropane Ring-Opening to Construct Sulfur-Containing Euphorbia Diterpenes. Organic letters 25 (4) (2023)
Shi-Yan Caroline Foo, Rana Abdelnabi, Laura Vangeel, Steven De Jonghe, Dirk Jochmans, Birgit Weynand, Johan Neyts
Ivermectin Does Not Protect against SARS-CoV-2 Infection in the Syrian Hamster Model. Microorganisms 10 (3) (2022)
Maria Giulia Nizi, Leentje Persoons, Angela Corona, Tommaso Felicetti, Giada Cernicchi, Serena Massari, Giuseppe Manfroni, Laura Vangeel, Maria Letizia Barreca, Francesca Esposito, Dirk Jochmans, Jessica Milia, Violetta Cecchetti, Dominique Schols, Johan Neyts, Enzo Tramontano, Stefano Sabatini, Steven De Jonghe, Oriana Tabarrini
Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity. ACS medicinal chemistry letters 13 (5) (2022)
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdwijn, Dominique Schols, Peng Zhan, Xinyong Liu
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors. Molecules (Basel, Switzerland) 28 (1) (2022)
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdwijn, Dominique Schols, Peng Zhan, Xinyong Liu
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors. Molecules (Basel, Switzerland) 28 (1) (2022)
Andrea Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis, Maria Kuzikov, Oliver Keminer, Markus Wolf, Bernhard Ellinger, Francesca Esposito, Angela Corona, Enzo Tramontano, Candida Manelfi, Katja Herzog, Dirk Jochmans, Steven De Jonghe, Winston Chiu, Thibault Francken, Joost Schepers, Caroline Collard, Kayvan Abbasi, Carsten Claussen, Vincenzo Summa, Andrea R Beccari, Johan Neyts, Philip Gribbon, Pieter Leyssen
Cytopathic SARS-CoV-2 screening on VERO-E6 cells in a large-scale repurposing effort. Scientific data 9 (1) (2022)
Andreas Luttens, Hjalmar Gullberg, Eldar Abdurakhmanov, Duy Duc Vo, Dario Akaberi, Vladimir O Talibov, Natalia Nekhotiaeva, Laura Vangeel, Steven De Jonghe, Dirk Jochmans, Janina Krambrich, Ali Tas, Bo Lundgren, Ylva Gravenfors, Alexander J Craig, Yoseph Atilaw, Anja Sandström, Lindon W K Moodie, Åke Lundkvist, Martijn J van Hemert, Johan Neyts, Johan Lennerstrand, Jan Kihlberg, Kristian Sandberg, U Helena Danielson, Jens Carlsson
Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. Journal of the American Chemical Society 144 (7) (2022)
Tom Van Loy, Steven De Jonghe, Karolien Castermans, Wouter Dheedene, Reinout Stoop, Lars Verschuren, Matthias Versele, Patrick Chaltin, Aernout Luttun, Dominique Schols
Stimulation of the atypical chemokine receptor 3 (ACKR3) by a small-molecule agonist attenuates fibrosis in a preclinical liver but not lung injury model. Cellular and molecular life sciences : CMLS 79 (6) (2022)
Shenghua Gao, Letian Song, Hongtao Xu, Antonios Fikatas, Merel Oeyen, Steven De Jonghe, Fabao Zhao, Lanlan Jing, Dirk Jochmans, Laura Vangeel, Yusen Cheng, Dongwei Kang, Johan Neyts, Piet Herdwijn, Dominique Schols, Peng Zhan, Xinyong Liu
Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors. Molecules (Basel, Switzerland) 28 (1) (2022)
Rana Abdelnabi, Shi-Yan Caroline Foo, Dirk Jochmans, Laura Vangeel, Steven De Jonghe, Patrick Augustijns, Raf Mols, Birgit Weynand, Thanaporn Wattanakul, Richard M Hoglund, Joel Tarning, Charles E Mowbray, Peter Sjö, Fanny Escudie, Ivan Scandale, Eric Chatelain, Johan Neyts
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern. Nature communications 13 (1) (2022)
Suresh Gangadevi, Vishnu Nayak Badavath, Abhishek Thakur, Na Yin, Steven De Jonghe, Orlando Acevedo, Dirk Jochmans, Pieter Leyssen, Ke Wang, Johan Neyts, Tao Yujie, Galia Blum
Kobophenol A Inhibits Binding of Host ACE2 Receptor with Spike RBD Domain of SARS-CoV-2, a Lead Compound for Blocking COVID-19. The journal of physical chemistry letters 12 (7) (2021)
Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Markus Wolf, Bernhard Ellinger, Carsten Claussen, Gerd Geisslinger, Angela Corona, Daniela Iaconis, Carmine Talarico, Candida Manelfi, Rolando Cannalire, Sybille Krauß, Jonas Gossen, Simone Albani, Francesco Musiani, Katja Herzog, Yang Ye, Barbara Giabbai, Nicola Demitri, Dirk Jochmans, Steven De Jonghe, Jasper Rymenants, Vincenzo Summa, Enzo Tramontano, Andrea R Beccari, Pieter Leyssen, Paola Storici, Johan Neyts, Philip Gribbon, Andrea Zaliani
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen. ACS pharmacology & translational science 4 (3) (2021)
Abhimanyu K Singh, Sergio E Martinez, Weijie Gu, Hoai Nguyen, Dominique Schols, Piet Herdewijn, Steven De Jonghe, Kalyan Das
Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - targeting P-pocket by fragment screening. Nature communications 12 (1) (2021)
Min Luo, Shuo Wu, Raj Kalkeri, Roger G Ptak, Tianlun Zhou, Lieve Van Mellaert, Chuanmin Wang, Shrinivas G Dumbre, Timothy Block, Elisabetta Groaz, Steven De Jonghe, Yuhuan Li, Piet Herdwijn
Scalable Synthesis, In Vitro cccDNA Reduction, and In Vivo Antihepatitis B Virus Activity of a Phosphonomethoxydeoxythreosyl Adenine Prodrug. Journal of medicinal chemistry 63 (22) (2020)
Weijie Gu, Sergio Martinez, Hoai Nguyen, Hongtao Xu, Piet Herdwijn, Steven De Jonghe, Kalyan Das
Tenofovir-Amino Acid Conjugates Act as Polymerase Substrates-Implications for Avoiding Cellular Phosphorylation in the Discovery of Nucleotide Analogues. Journal of medicinal chemistry 64 (1) (2020)
Sònia Abás, Sergio Rodríguez-Arévalo, Andrea Bagán, Christian Griñán-Ferré, Foteini Vasilopoulou, Iria Brocos-Mosquera, Carolina Muguruza, Belén Pérez, Elies Molins, Francisco Javier Luque, Pilar Pérez-Lozano, Steven De Jonghe, Dirk Daelemans, Lieve Naesens, José Brea, M Isabel Loza, Elena Hernández-Hernández, Jesús A García-Sevilla, M Julia García-Fuster, Milica Radan, Teodora Djikic, Katarina Nikolic, Mercé Pallàs, Luis F Callado, Carmen Escolano
Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease. Journal of medicinal chemistry 63 (7) (2020)
Sònia Abás, Sergio Rodríguez-Arévalo, Andrea Bagán, Christian Griñán-Ferré, Foteini Vasilopoulou, Iria Brocos-Mosquera, Carolina Muguruza, Belén Pérez, Elies Molins, Francisco Javier Luque, Pilar Pérez-Lozano, Steven De Jonghe, Dirk Daelemans, Lieve Naesens, José Brea, M Isabel Loza, Elena Hernández-Hernández, Jesús A García-Sevilla, M Julia García-Fuster, Milica Radan, Teodora Djikic, Katarina Nikolic, Mercé Pallàs, Luis F Callado, Carmen Escolano
Correction to Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease. Journal of medicinal chemistry 63 (18) (2020)
Randy Wouters, Junjun Tian, Piet Herdewijn, Steven De Jonghe
A Scaffold-Hopping Strategy toward the Identification of Inhibitors of Cyclin G Associated Kinase. ChemMedChem 14 (2) (2019)
Jakub Modranka, Jiahong Li, Anastasia Parchina, Michiel Vanmeert, Shrinivas G Dumbre, Mayla Salman, Hannu Myllykallio, Hubert F Becker, Roeland Vanhoutte, Lia Margamuljana, Hoai Nguyen, Rania Abu El-Asrar, Jef Rozenski, Piet Herdwijn, Steven De Jonghe, Eveline Lescrinier
Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase X. ChemMedChem 14 (6) (2019)
Sven Verdonck, Szu-Yuan Pu, Fiona J Sorrell, Jon M Elkins, Matheus Froeyen, Ling-Jie Gao, Laura I Prugar, Danielle E Dorosky, Jennifer M Brannan, Rina Barouch-Bentov, Stefan Knapp, John M Dye, Piet Herdwijn, Shirit Einav, Steven De Jonghe
Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3- b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity. Journal of medicinal chemistry 62 (12) (2019)
Szu-Yuan Pu, Randy Wouters, Stanford Schor, Jef Rozenski, Rina Barouch-Bentov, Laura I Prugar, Cecilia M O'Brien, Jennifer M Brannan, John M Dye, Piet Herdwijn, Steven De Jonghe, Shirit Einav
Optimization of Isothiazolo[4,3- b]pyridine-Based Inhibitors of Cyclin G Associated Kinase (GAK) with Broad-Spectrum Antiviral Activity. Journal of medicinal chemistry 61 (14) (2018)
Peng Nie, Elisabetta Groaz, Steven De Jonghe, Eveline Lescrinier, Piet Herdwijn
Synthesis of a C-Nucleoside Phosphonate by Base-Promoted Epimerization. Organic letters 20 (4) (2018)
Swarup De, Amit M Jabgunde, Rahul S Patil, Steven De Jonghe, Leonid Beigelman, Piet Herdwijn
Synthesis of Protected Amino Hexitol Nucleosides as Building Blocks for Oligonucleotide Synthesis. The Journal of organic chemistry 83 (24) (2018)
Qingfeng Li, Eveline Lescrinier, Elisabetta Groaz, Leentje Persoons, Dirk Daelemans, Piet Herdwijn, Steven De Jonghe
Synthesis and Biological Evaluation of Pyrrolo[2,1-f][1,2,4]triazine C-Nucleosides with a Ribose, 2'-Deoxyribose, and 2',3'-Dideoxyribose Sugar Moiety. ChemMedChem 13 (1) (2017)
Swarup De, Steven De Jonghe, Piet Herdwijn
Synthesis of a 3'-Fluoro-3'-deoxytetrose Adenine Phosphonate. The Journal of organic chemistry 82 (18) (2017)