Stephane Angers (Stéphane Angers)

Scopus Author ID ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 39

Top Venues

Development (Cambridge, England)

Science advances

Nature communications

bioRxiv : the preprint server for biology

University of Toronto

Université de Montréal (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Toronto Jul 01 2017

Canada

Professor :: Biochemistry

University of Toronto Jul 01 2017

Canada

Professor :: Pharmaceutical Sciences

University of Toronto

Canada

Associate Dean of Research :: Faculty of Pharmacy

University of Toronto - Jul 01 2017

Canada

Associate Professor :: Faculty of Pharmacy

University of Toronto

Canada

Associate Professor :: Biochemistry

Education History

Université de Montréal

Canada

PHD :: Biochemistry

McGill University

Canada

BSC :: Biochemistry

Publications

Yassine El Bakkouri, Rony Chidiac, Chantal Delisle, Jeanne Corriveau, Gael Cagnone, Vanda Gaonac'h-Lovejoy, Ashley Chin, Éric Lécuyer, Stephane Angers, Jean-Sébastien Joyal, Ivan Topisirovic, Laura Hulea, Alexandre Dubrac, Jean-Philippe Gratton
ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis. Nature communications 15 (1) (2024)
Hideyuki Komori, Geeta Rastogi, John Paul Bugay, Hua Luo, Sichun Lin, Stephane Angers, Craig A Smibert, Howard D Lipshitz, Cheng-Yu Lee
Post-transcriptional regulatory pre-complex assembly drives timely cell-state transitions during differentiation. bioRxiv : the preprint server for biology (2024)
Yassine El Bakkouri, Rony Chidiac, Chantal Delisle, Jeanne Corriveau, Gael Cagnone, Vanda Gaonac'h-Lovejoy, Ashley Chin, Éric Lécuyer, Stephane Angers, Jean-Sébastien Joyal, Ivan Topisirovic, Laura Hulea, Alexandre Dubrac, Jean-Philippe Gratton
ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis. Nature communications 15 (1) (2024)
Andy Yang, Rony Chidiac, Emma Russo, Hendrik Steenland, Quinn Pauli, Robert P Bonin, Levi L Blazer, Jarrett J Adams, Sachdev S Sidhu, Aleksandrina Goeva, Ali Salahpour, Stephane Angers
Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification. Development (Cambridge, England) 151 (5) (2024)
Andy Yang, Rony Chidiac, Emma Russo, Hendrik Steenland, Quinn Pauli, Robert P Bonin, Levi L Blazer, Jarrett J Adams, Sachdev S Sidhu, Aleksandrina Goeva, Ali Salahpour, Stephane Angers
Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification. Development (Cambridge, England) 151 (5) (2024)
Andy Yang, Rony Chidiac, Emma Russo, Hendrik Steenland, Quinn Pauli, Robert P Bonin, Levi L Blazer, Jarrett J Adams, Sachdev S Sidhu, Aleksandrina Goeva, Ali Salahpour, Stephane Angers
Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification. Development (Cambridge, England) 151 (5) (2024)
Graham MacLeod, Fatemeh Molaei, Shahan Haider, Maira P Almeida, Sichun Lin, Michelle Kushida, Haresh Sureshkumar, Jasmine K Bhatti, Jack Q Lu, Daniel Schramek, Peter B Dirks, Stephane Angers
Fitness Screens Map State-Specific Glioblastoma Stem Cell Vulnerabilities. Cancer research (2024)
Andy Yang, Rony Chidiac, Emma Russo, Hendrik Steenland, Quinn Pauli, Robert P Bonin, Levi L Blazer, Jarrett J Adams, Sachdev S Sidhu, Aleksandrina Goeva, Ali Salahpour, Stephane Angers
Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification. Development (Cambridge, England) 151 (5) (2024)
Hideyuki Komori, Geeta Rastogi, John Paul Bugay, Hua Luo, Sichun Lin, Stephane Angers, Craig A Smibert, Howard D Lipshitz, Cheng-Yu Lee
Post-transcriptional regulatory pre-complex assembly drives timely cell-state transitions during differentiation. bioRxiv : the preprint server for biology (2024)
Yassine El Bakkouri, Rony Chidiac, Chantal Delisle, Jeanne Corriveau, Gael Cagnone, Vanda Gaonac'h-Lovejoy, Ashley Chin, Éric Lécuyer, Stephane Angers, Jean-Sébastien Joyal, Ivan Topisirovic, Laura Hulea, Alexandre Dubrac, Jean-Philippe Gratton
ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis. Nature communications 15 (1) (2024)
Hideyuki Komori, Geeta Rastogi, John Paul Bugay, Hua Luo, Sichun Lin, Stephane Angers, Craig A Smibert, Howard D Lipshitz, Cheng-Yu Lee
Post-transcriptional regulatory pre-complex assembly drives timely cell-state transitions during differentiation. bioRxiv : the preprint server for biology (2024)
Andy Yang, Rony Chidiac, Emma Russo, Hendrik Steenland, Quinn Pauli, Robert P Bonin, Levi L Blazer, Jarrett J Adams, Sachdev S Sidhu, Aleksandrina Goeva, Ali Salahpour, Stephane Angers
Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification. Development (Cambridge, England) (2024)
Andy Yang, Rony Chidiac, Emma Russo, Hendrik Steenland, Quinn Pauli, Robert P Bonin, Levi L Blazer, Jarrett J Adams, Sachdev S Sidhu, Aleksandrina Goeva, Ali Salahpour, Stephane Angers
Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification. Development (Cambridge, England) 151 (5) (2024)
Zongjie Wang, Hansen Wang, Sichun Lin, Stephane Angers, Edward H Sargent, Shana O Kelley
Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators. Science advances 10 (19) (2024)
Islam E Elkholi, Amélie Robert, Camille Malouf, Hellen Kuasne, Stanislav Drápela, Graham MacLeod, Steven Hébert, Alain Pacis, Virginie Calderon, Claudia L Kleinman, Ana P Gomes, Julio A Aguirre-Ghiso, Morag Park, Stephane Angers, Jean-François Côté
Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation. bioRxiv : the preprint server for biology (2024)
Zongjie Wang, Hansen Wang, Sichun Lin, Stephane Angers, Edward H Sargent, Shana O Kelley
Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators. Science advances 10 (19) (2024)
Xian Wang, Zheyuan Gong, Tiancong Wang, Junhui Law, Xin Chen, Siyi Wanggou, Jintian Wang, Binbin Ying, Michelle Francisco, Weifan Dong, Yi Xiong, Jerry J Fan, Graham MacLeod, Stephane Angers, Xue-Jun Li, Peter B Dirks, Xinyu Liu, Xi Huang, Yu Sun
Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes. Science advances 9 (13) (2023)
Xian Wang, Zheyuan Gong, Tiancong Wang, Junhui Law, Xin Chen, Siyi Wanggou, Jintian Wang, Binbin Ying, Michelle Francisco, Weifan Dong, Yi Xiong, Jerry J Fan, Graham MacLeod, Stephane Angers, Xue-Jun Li, Peter B Dirks, Xinyu Liu, Xi Huang, Yu Sun
Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes. Science advances 9 (13) (2023)
Tanja Sack, Piriththiv Dhavarasa, Daniel Szames, Siobhan O'Brien, Stephane Angers, Shana O Kelley
CRISPR Screening in Tandem with Targeted mtDNA Damage Reveals WRNIP1 Essentiality. bioRxiv : the preprint server for biology (2023)
Mahmoud Labib, Zongjie Wang, Yunhye Kim, Sichun Lin, Abdalla Abdrabou, Hanie Yousefi, Pei-Ying Lo, Stephane Angers, Edward H Sargent, Shana O Kelley
Identification of druggable regulators of cell secretion via a kinome-wide screen and high-throughput immunomagnetic cell sorting. Nature biomedical engineering (2023)
Siobhan O'Brien, Tajinder Ubhi, Lucie M Wolf, Krishna Gandhi, Sichun Lin, Naz Chaudary, Neesha C Dhani, Michael F Milosevic, Grant W Brown, Stephane Angers
FBXW7-loss sensitizes cells to ATR inhibition through induced mitotic catastrophe. Cancer research communications (2023)
Xian Wang, Zheyuan Gong, Tiancong Wang, Junhui Law, Xin Chen, Siyi Wanggou, Jintian Wang, Binbin Ying, Michelle Francisco, Weifan Dong, Yi Xiong, Jerry J Fan, Graham MacLeod, Stephane Angers, Xue-Jun Li, Peter B Dirks, Xinyu Liu, Xi Huang, Yu Sun
Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes. Science advances 9 (13) (2023)
Siobhan O'Brien, Susan Kelso, Zachary Steinhart, Stephen Orlicky, Monika Mis, Yunhye Kim, Sichun Lin, Frank Sicheri, Stephane Angers
SCF FBXW7 regulates G2-M progression through control of CCNL1 ubiquitination. EMBO reports 23 (12) (2022)
Thibault Houles, Geneviève Lavoie, Sami Nourreddine, Winnie Cheung, Éric Vaillancourt-Jean, Célia M Guérin, Mathieu Bouttier, Benoit Grondin, Sichun Lin, Marc K Saba-El-Leil, Stephane Angers, Sylvain Meloche, Philippe P Roux
CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. Nature communications 13 (1) (2022)
Stephane Angers
Frizzled does not get bent out of shape by Wnt. Science signaling 15 (748) (2022)
Fan Xia, Yuan Ma, Kangfu Chen, Bill T V Duong, Sharif U Ahmed, Randy Atwal, David N Philpott, Troy Ketela, Jennifer Pantea, Sichun Lin, Stephane Angers, Shana O Kelley
Genome-wide in vivo screen of circulating tumor cells identifies SLIT2 as a regulator of metastasis. Science advances 8 (35) (2022)
Elodie Blondel-Tepaz, Marie Leverve, Badr Sokrat, Justine S Paradis, Milena Kosic, Kusumika Saha, Cédric Auffray, Evelyne Lima-Fernandes, Alessia Zamborlini, Anne Poupon, Louis Gaboury, Jane Findlay, George S Baillie, Hervé Enslen, Michel Bouvier, Stephane Angers, Stefano Marullo, Mark G H Scott
The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axis. Oncogene 40 (12) (2021)
Paul Guilhamon, Charles Chesnelong, Michelle M Kushida, Ana Nikolic, Divya Singhal, Graham MacLeod, Seyed Ali Madani Tonekaboni, Florence Mg Cavalli, Christopher Arlidge, Nishani Rajakulendran, Naghmeh Rastegar, Xiaoguang Hao, Rozina Hassam, Laura J Smith, Heather Whetstone, Fiona J Coutinho, Bettina Nadorp, Katrina I Ellestad, H Artee Luchman, Jennifer Ai-Wen Chan, Molly S Shoichet, Michael D Taylor, Benjamin Haibe-Kains, Samuel Weiss, Stephane Angers, Marco Gallo, Peter B Dirks, Mathieu Lupien
Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival. eLife 10 (2021)
Laura M Richards, Owen K N Whitley, Graham MacLeod, Florence M G Cavalli, Fiona J Coutinho, Julia E Jaramillo, Nataliia Svergun, Mazdak Riverin, Danielle C Croucher, Michelle Kushida, Kenny Yu, Paul Guilhamon, Naghmeh Rastegar, Moloud Ahmadi, Jasmine K Bhatti, Danielle A Bozek, Naijin Li, Lilian Lee, Clare Che, Erika Luis, Nicole I Park, Zhiyu Xu, Troy Ketela, Richard A Moore, Marco A Marra, Julian Spears, Michael D Cusimano, Sunit Das, Mark Bernstein, Benjamin Haibe-Kains, Mathieu Lupien, H Artee Luchman, Samuel Weiss, Stephane Angers, Peter B Dirks, Gary D Baider, Trevor J Pugh
Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity. Nature cancer 2 (2) (2021)
Stephane Angers
Wnt signaling inhibition confers induced synthetic lethality to PARP inhibitors. EMBO molecular medicine 13 (4) (2021)
Rony Chidiac, Md Abedin, Graham MacLeod, Andy Yang, Pierre E Thibeault, Levi L Blazer, Jarrett J Adams, Lingling Zhang, Heidi Roehrich, Ha-Neul Jo, Somasekar Seshagiri, Sachdev S Sidhu, Harald J Junge, Stephane Angers
A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy. EMBO molecular medicine 13 (7) (2021)
Léo Aubert, Neethi Nandagopal, Zachary Steinhart, Geneviève Lavoie, Sami Nourreddine, Jacob Berman, Marc K Saba-El-Leil, David Papadopoli, Sichun Lin, Traver Hart, Graham MacLeod, Ivan Topisirovic, Louis Gaboury, Christoph J Fahrni, Daniel Schramek, Sylvain Meloche, Stephane Angers, Philippe P Roux
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer. Nature communications 11 (1) (2020)
Nishani Rajakulendran, Katherine J Rowland, Hayden J Selvadurai, Moloud Ahmadi, Nicole I Park, Sergey Naumenko, Sonam Dolma, Ryan J Ward, Milly So, Lilian Lee, Graham MacLeod, Clarissa Pasiliao, Caroline Brandon, Ian D Clarke, Michael D Cusimano, Mark Bernstein, Nizar Batada, Stephane Angers, Peter B Dirks
Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells. Genes & development 33 (9-10) (2019)
Yuyong Tao, Monika Mis, Levi Blazer, Mart Ustav, Zachary Steinhart, Rony Chidiac, Elli Kubarakos, Siobhan O'Brien, Xiaomei Wang, Nick Jarvik, Nish Patel, Jarrett J Adams, Jason Moffat, Stephane Angers, Sachdev S Sidhu
Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice. eLife 8 (2019)
Barbara Mair, Peter M Aldridge, Randy S Atwal, David Philpott, Meng Zhang, Sanna N Masud, Mahmoud Labib, Amy H Y Tong, Edward H Sargent, Stephane Angers, Jason Moffat, Shana O Kelley
High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting. Nature biomedical engineering 3 (10) (2019)
Aaron H Nile, Felipe de Sousa E Melo, Susmith Mukund, Robert Piskol, Simon Hansen, Lijuan Zhou, Yingnan Zhang, Yue Fu, Emily B Gogol, László G Kömüves, Zora Modrusan, Stephane Angers, Yvonne Franke, Christopher Koth, Wayne J Fairbrother, Weiru Wang, Frederic J de Sauvage, Rami N Hannoush
A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nature chemical biology 14 (6) (2018)
Zachary Steinhart, Stephane Angers
Wnt signaling in development and tissue homeostasis. Development (Cambridge, England) 145 (11) (2018)
Celine Lacroix, Inbar Fish, Hayarpi Torosyan, Pranavan Parathaman, John J Irwin, Brian K Shoichet, Stephane Angers
Identification of Novel Smoothened Ligands Using Structure-Based Docking. PloS one 11 (8) (2016)
Zachary Steinhart, Zvezdan Pavlovic, Megha Chandrashekhar, Traver Hart, Xiaowei Wang, Xiaoyu Zhang, Mélanie Robitaille, Kevin R Brown, Sridevi Jaksani, René Overmeer, Sylvia F Boj, Jarrett Adams, James Pan, Hans Clevers, Sachdev Sidhu, Jason Moffat, Stephane Angers
Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors. Nature medicine 23 (1) (2016)

Stephane Angers.css-eqlu8i{font-size:small;padding-left:4px;} (Stéphane Angers)

Publication Activity (10 Years)

Top Topics

Top Venues

Stephane Angers (Stéphane Angers)