Guillaume Lettre

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 19

Top Topics

Sickle Cell Disease

Low Density Lipoprotein

Coronary Artery Disease

Top Venues

Nature genetics

American journal of hematology

European heart journal

This page only lists publications with an associated author ORCID identifier.

Publications

Jayoung Ryu, Sam Barkal, Tian Yu, Martin Jankowiak, Yunzhuo Zhou, Matthew Francoeur, Quang Vinh Phan, Zhijian Li, Manuel Tognon, Lara Brown, Michael I Love, Vineel Bhat, Guillaume Lettre, David Benjamin Ascher, Christopher A Cassa, Richard I Sherwood, Luca Pinello
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification. Nature genetics (2024)
Jayoung Ryu, Sam Barkal, Tian Yu, Martin Jankowiak, Yunzhuo Zhou, Matthew Francoeur, Quang Vinh Phan, Zhijian Li, Manuel Tognon, Lara Brown, Michael I Love, Vineel Bhat, Guillaume Lettre, David Benjamin Ascher, Christopher A Cassa, Richard I Sherwood, Luca Pinello
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification. Nature genetics (2024)
Jayoung Ryu, Sam Barkal, Tian Yu, Martin Jankowiak, Yunzhuo Zhou, Matthew Francoeur, Quang Vinh Phan, Zhijian Li, Manuel Tognon, Lara Brown, Michael I Love, Vineel Bhat, Guillaume Lettre, David Benjamin Ascher, Christopher A Cassa, Richard I Sherwood, Luca Pinello
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification. Nature genetics (2024)
Jayoung Ryu, Sam Barkal, Tian Yu, Martin Jankowiak, Yunzhuo Zhou, Matthew Francoeur, Quang Vinh Phan, Zhijian Li, Manuel Tognon, Lara Brown, Michael I Love, Vineel Bhat, Guillaume Lettre, David Benjamin Ascher, Christopher A Cassa, Richard I Sherwood, Luca Pinello
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification. Nature genetics 56 (5) (2024)
Jayoung Ryu, Sam Barkal, Tian Yu, Martin Jankowiak, Yunzhuo Zhou, Matthew Francoeur, Quang Vinh Phan, Zhijian Li, Manuel Tognon, Lara Brown, Michael I Love, Vineel Bhat, Guillaume Lettre, David Benjamin Ascher, Christopher A Cassa, Richard I Sherwood, Luca Pinello
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification. Nature genetics 56 (5) (2024)
Jayoung Ryu, Sam Barkal, Tian Yu, Martin Jankowiak, Yunzhuo Zhou, Matthew Francoeur, Quang Vinh Phan, Zhijian Li, Manuel Tognon, Lara Brown, Michael I Love, Vineel Bhat, Guillaume Lettre, David Benjamin Ascher, Christopher A Cassa, Richard I Sherwood, Luca Pinello
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification. Nature genetics 56 (5) (2024)
Thomas Pincez, Guillaume Lettre
Re-assessing the effect of fetal hemoglobin on stroke in the Cooperative Study of Sickle Cell Disease. American journal of hematology (2023)
Florian Wünnemann, Thierry Fotsing Tadjo, Mélissa Beaudoin, Simon Lalonde, Ken Sin Lo, Benjamin P Kleinstiver, Guillaume Lettre
Multimodal CRISPR perturbations of GWAS loci associated with coronary artery disease in vascular endothelial cells. PLoS genetics 19 (3) (2023)
Cantin Baron, Sarah Cherkaoui, Sandra Therrien-Laperriere, Yann Ilboudo, Raphaël Poujol, Pamela Mehanna, Melanie E Garrett, Marilyn J Telen, Allison E Ashley-Koch, Pablo Bartolucci, John D Rioux, Guillaume Lettre, Christine Des Rosiers, Matthieu Ruiz, Julie G Hussin
Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results. bioRxiv : the preprint server for biology (2023)
Guillaume Lettre
One step closer to linking GWAS SNPs with the right genes. Nature genetics 54 (6) (2022)
Steffany Grondin, Brianna Davies, Julia Cadrin-Tourigny, Christian Steinberg, Christopher C Cheung, Paloma Jorda, Jeffrey S Healey, Martin S Green, Shubhayan Sanatani, Wael Alqarawi, Paul Angaran, Laura Arbour, Pavel Antiperovitch, Habib Khan, Richard Leather, Peter G Guerra, Lena Rivard, Christopher S Simpson, Martin Gardner, Ciorsti MacIntyre, Colette Seifer, Anne Fournier, Jacqueline E Joza, Michael H Gollob, Guillaume Lettre, Mario Talajic, Zachary W M Laksman, Jason D Roberts, Andrew D Krahn, Rafik Tadros
Importance of genetic testing in unexplained cardiac arrest. European heart journal 43 (32) (2022)
Thomas Pincez, Simon S K Lee, Yann Ilboudo, Michael H Preuss, Anne-Laure Pham-Hung D'Alexandry D'Orengiani, Pablo Bartolucci, Frédéric Galactéros, Philippe Joly, Daniel E Bauer, Ruth J F Loos, R Coleman Lindsley, Guillaume Lettre
Clonal hematopoiesis in sickle cell disease. Blood 138 (21) (2021)
Simon Lalonde, Valérie-Anne Codina-Fauteux, Sébastian Méric de Bellefon, Francis Leblanc, Mélissa Beaudoin, Marie-Michelle Simon, Rola Dali, Tony Kwan, Ken Sin Lo, Tomi Pastinen, Guillaume Lettre
Integrative analysis of vascular endothelial cell genomic features identifies AIDA as a coronary artery disease candidate gene. Genome biology 20 (1) (2019)
Valérie-Anne Codina-Fauteux, Mélissa Beaudoin, Simon Lalonde, Ken Sin Lo, Guillaume Lettre
PHACTR1 splicing isoforms and eQTLs in atherosclerosis-relevant human cells. BMC medical genetics 19 (1) (2018)
Ariel Molly Wilson, Zhuo Shao, Vanessa Grenier, Gaelle Tagne Mawambo, Jean-François Daudelin, Agnieszka Dejda, Frédérique Pilon, Natalija Popovic, Salix Boulet, Célia Parinot, Malika Oubaha, Nathalie Labrecque, Vincent de Guire, Mathieu Laplante, Guillaume Lettre, Florian Sennlaub, Jean-Sebastien Joyal, Michel Meunier, Przemyslaw Sapieha
Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome. Science immunology 3 (21) (2018)
Yann Ilboudo, Pablo Bartolucci, Melanie E Garrett, Allison Ashley-Koch, Marilyn Telen, Carlo Brugnara, Frédéric Galactéros, Guillaume Lettre
A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients. American journal of hematology 93 (11) (2018)
Laura M Raffield, Jacob C Ulirsch, Rakhi P Naik, Samuel Lessard, Robert E Handsaker, Deepti Jain, Hyun M Kang, Nathan D Pankratz, Paul L Auer, Erik L Bao, Joshua D Smith, Leslie A Lange, Ethan M Lange, Yun Li, Timothy A Thornton, Bessie A Young, Goncalo R Abecasis, Cathy C Laurie, Deborah A Nickerson, Steven A McCarroll, Adolfo Correa, James G Wilson, null null, Guillaume Lettre, Vijay G Sankaran, Alex P Reiner
Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease. PLoS genetics 14 (3) (2018)
Abdou Mousas, Georgios Ntritsos, Ming-Huei Chen, Ci Song, Jennifer E Huffman, Joanna Tzoulaki, Paul Elliott, Bruce M Psaty, null null, Paul L Auer, Andrew D Johnson, Evangelos Evangelou, Guillaume Lettre, Alexander P Reiner
Rare coding variants pinpoint genes that control human hematological traits. PLoS genetics 13 (8) (2017)
Simon Lalonde, Oliver A Stone, Samuel Lessard, Adam Lavertu, Jessica Desjardins, Mélissa Beaudoin, Manuel Rivas, Didier Y R Stainier, Guillaume Lettre
Frameshift indels introduced by genome editing can lead to in-frame exon skipping. PloS one 12 (6) (2017)