Harald Hübner

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 18

Top Topics

Single Molecule

Molecular Dynamics Simulations

Postoperative Pain

Fluorescent Probe

Top Venues

Nature communications

Chemistry (Weinheim an der Bergstrasse, Germany)

Journal of medicinal chemistry

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Antonios Drakopoulos, Zsombor Koszegi, Kerstin Seier, Harald Hübner, Damien Maurel, Rémy Sounier, Sébastien Granier, Peter Gmeiner, Davide Calebiro, Michael Decker
Design, Synthesis, and Characterization of New δ Opioid Receptor-Selective Fluorescent Probes and Applications in Single-Molecule Microscopy of Wild-Type Receptors. Journal of medicinal chemistry (2024)
Fabian J Ertl, Sergei Kopanchuk, Nicola C Dijon, Santa Veikšina, Maris-Johanna Tahk, Tõnis Laasfeld, Franziska Schettler, Albert O Gattor, Harald Hübner, Nataliya Archipowa, Johannes Köckenberger, Markus R Heinrich, Peter Gmeiner, Roger Jan Kutta, Nicholas D Holliday, Ago Rinken, Max Keller
Dually Labeled Neurotensin NTS 1 R Ligands for Probing Radiochemical and Fluorescence-Based Binding Assays. Journal of medicinal chemistry (2024)
Antonios Drakopoulos, Zsombor Koszegi, Kerstin Seier, Harald Hübner, Damien Maurel, Rémy Sounier, Sébastien Granier, Peter Gmeiner, Davide Calebiro, Michael Decker
Design, Synthesis, and Characterization of New δ Opioid Receptor-Selective Fluorescent Probes and Applications in Single-Molecule Microscopy of Wild-Type Receptors. Journal of medicinal chemistry 67 (15) (2024)
Alexandra Sink, Hubert Gerwe, Harald Hübner, Valérie Boivin-Jahns, Julia Fender, Kristina Lorenz, Peter Gmeiner, Michael Decker
"Photo-Adrenalines": Photoswitchable β 2 -Adrenergic Receptor Agonists as Molecular Probes for the Study of Spatiotemporal Adrenergic Signaling. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (11) (2024)
Alexandra Sink, Hubert Gerwe, Harald Hübner, Valérie Boivin-Jahns, Julia Fender, Kristina Lorenz, Peter Gmeiner, Michael Decker
"Photo-Adrenalines": Photoswitchable β 2 -Adrenergic Receptor Agonists as Molecular Probes for the Study of Spatiotemporal Adrenergic Signaling. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (11) (2024)
Alexandra Sink, Hubert Gerwe, Harald Hübner, Valérie Boivin-Jahns, Julia Fender, Kristina Lorenz, Peter Gmeiner, Michael Decker
"Photo-Adrenalines": Photoswitchable β 2 -Adrenergic Receptor Agonists as Molecular Probes for the Study of Spatiotemporal Adrenergic Signaling. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Antonios Drakopoulos, Zsombor Koszegi, Kerstin Seier, Harald Hübner, Damien Maurel, Rémy Sounier, Sébastien Granier, Peter Gmeiner, Davide Calebiro, Michael Decker
Design, Synthesis, and Characterization of New δ Opioid Receptor-Selective Fluorescent Probes and Applications in Single-Molecule Microscopy of Wild-Type Receptors. Journal of medicinal chemistry 67 (15) (2024)
Jun Xu, Qinggong Wang, Harald Hübner, Yunfei Hu, Xiaogang Niu, Haoqing Wang, Shoji Maeda, Asuka Inoue, Yuyong Tao, Peter Gmeiner, Yang Du, Changwen Jin, Brian K Kobilka
Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature communications 14 (1) (2023)
Jun Xu, Qinggong Wang, Harald Hübner, Yunfei Hu, Xiaogang Niu, Haoqing Wang, Shoji Maeda, Asuka Inoue, Yuyong Tao, Peter Gmeiner, Yang Du, Changwen Jin, Brian K Kobilka
Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature communications 14 (1) (2023)
Xinyu Xu, Jeremy Shonberg, Jonas Kaindl, Mary J Clark, Anne Stößel, Luis Maul, Daniel Mayer, Harald Hübner, Kunio Hirata, A J Venkatakrishnan, Ron O Dror, Brian K Kobilka, Roger K Sunahara, Xiangyu Liu, Peter Gmeiner
Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics. Nature communications 14 (1) (2023)
Xinyu Xu, Jeremy Shonberg, Jonas Kaindl, Mary J Clark, Anne Stößel, Luis Maul, Daniel Mayer, Harald Hübner, Kunio Hirata, A J Venkatakrishnan, Ron O Dror, Brian K Kobilka, Roger K Sunahara, Xiangyu Liu, Peter Gmeiner
Author Correction: Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics. Nature communications 14 (1) (2023)
Jun Xu, Qinggong Wang, Harald Hübner, Yunfei Hu, Xiaogang Niu, Haoqing Wang, Shoji Maeda, Asuka Inoue, Yuyong Tao, Peter Gmeiner, Yang Du, Changwen Jin, Brian K Kobilka
Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature communications 14 (1) (2023)
Elissa A Fink, Jun Xu, Harald Hübner, Joao M Braz, Philipp Seemann, Charlotte Avet, Veronica Craik, Dorothée Weikert, Maximilian F Schmidt, Chase M Webb, Nataliya A Tolmachova, Yurii S Moroz, Xi Ping Huang, Chakrapani Kalyanaraman, Stefan Gahbauer, Geng Chen, Zheng Liu, Matthew P Jacobson, John J Irwin, Michel Bouvier, Yang Du, Brian K Shoichet, Allan I Basbaum, Peter Gmeiner
Structure-based discovery of nonopioid analgesics acting through the α 2A -adrenergic receptor. Science (New York, N.Y.) 377 (6614) (2022)
Jun Xu, Sheng Cao, Harald Hübner, Dorothée Weikert, Geng Chen, Qiuyuan Lu, Daopeng Yuan, Peter Gmeiner, Zheng Liu, Yang Du
Structural insights into ligand recognition, activation, and signaling of the α 2A adrenergic receptor. Science advances 8 (9) (2022)
Ranit Lahmy, Harald Hübner, Maximilian F Schmidt, Daniel Lachmann, Peter Gmeiner, Burkhard König
Photochromic Fentanyl Derivatives for Controlled μ-Opioid Receptor Activation. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (63) (2022)
Marc Bathe-Peters, Philipp Gmach, Horst-Holger Boltz, Jürgen Einsiedel, Michael Gotthardt, Harald Hübner, Peter Gmeiner, Martin J Lohse, Paolo Annibale
Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America 118 (23) (2021)
Jan Hellmann, Matthäus Drabek, Jie Yin, Jakub Gunera, Theresa Pröll, Frank Kraus, Christopher J Langmead, Harald Hübner, Dorothée Weikert, Peter Kolb, Daniel M Rosenbaum, Peter Gmeiner
Structure-based development of a subtype-selective orexin 1 receptor antagonist. Proceedings of the National Academy of Sciences of the United States of America 117 (30) (2020)
Jasmin Krüll, Stefanie K Fehler, Laura Hofmann, Natascha Nebel, Simone Maschauer, Olaf Prante, Peter Gmeiner, Harald Lanig, Harald Hübner, Markus R Heinrich
Synthesis, Radiosynthesis and Biological Evaluation of Buprenorphine-Derived Phenylazocarboxamides as Novel μ-Opioid Receptor Ligands. ChemMedChem 15 (13) (2020)