Hellmut G Augustin (Hellmut Augustin)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 34

Top Venues

Cancer research

The Journal of experimental medicine

Nature cancer

Nature communications

Medical Faculty Mannheim, University of Heidelberg and German Cancer Research Center

Cornell University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Medical Faculty Mannheim, University of Heidelberg and German Cancer Research Center

Germany

Aventis Foundation-endowed Chair for Vascular Biology and Angiogenesis Research :: Joint Research Division Vascular Biology

Medical Faculty of the Albert-Ludwigs-University Freiburg

Germany

Adjunct Professor

Institute of Molecular Oncology, Tumor Biology Center

Germany

Head :: Department of Vascular Biology & Angiogenesis Research

University of Göttingen

Germany

Research Assistant Professor (C2) :: Clinic for Gynecology and Obstetrics

University of Göttingen

Germany

Research Assistant Professor (C1) :: Clinic for Gynecology and Obstetrics

Cornell University

United States

Veterinary Assistant :: Cancer Biology Laboratories, Department of Pathology

Cornell University

United States

Postdoctoral Associate :: Immunopathology Laboratory, Department of Pathology

School of Veterinary

Germany

Scientific Assistant :: Institute of Pathology

School of Veterinary Medicine

Germany

Assistant :: Institute of Pathology

Education History

Cornell University Aug 24 1992 - Aug 24 1992

United States

PHD :: Department of Pathology

Publications

Moritz Jakab, Ki Hong Lee, Alexey Uvarovskii, Svetlana Ovchinnikova, Shubhada R Kulkarni, Sevinç Jakab, Till Rostalski, Carleen Spegg, Simon Anders, Hellmut G Augustin
Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency. Nature cancer (2024)
Moritz Jakab, Ki Hong Lee, Alexey Uvarovskii, Svetlana Ovchinnikova, Shubhada R Kulkarni, Sevinç Jakab, Till Rostalski, Carleen Spegg, Simon Anders, Hellmut G Augustin
Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency. Nature cancer 5 (5) (2024)
Moritz Jakab, Ki Hong Lee, Alexey Uvarovskii, Svetlana Ovchinnikova, Shubhada R Kulkarni, Sevinç Jakab, Till Rostalski, Carleen Spegg, Simon Anders, Hellmut G Augustin
Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency. Nature cancer 5 (5) (2024)
Moritz Jakab, Ki Hong Lee, Alexey Uvarovskii, Svetlana Ovchinnikova, Shubhada R Kulkarni, Sevinç Jakab, Till Rostalski, Carleen Spegg, Simon Anders, Hellmut G Augustin
Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency. Nature cancer 5 (5) (2024)
Lavinia Arseni, Rakesh Sharma, Norman Mack, Deepthi Nagalla, Sibylle Ohl, Thomas Hielscher, Mahak Singhal, Robert Pilz, Hellmut G Augustin, Roger Sandhoff, Christel Herold-Mende, Björn Tews, Peter Lichter, Martina Seiffert
Sphingosine-1-Phosphate Recruits Macrophages and Microglia and Induces a Pro-Tumorigenic Phenotype That Favors Glioma Progression. Cancers 15 (2) (2023)
Matthia A Karreman, Alexander T Bauer, Gergely Solecki, Anna Sophie Berghoff, Chanté D Mayer, Katharina Frey, Nils R Hebach, Manuel J Feinauer, Nicole L Schieber, Cedric Tehranian, Luc Mercier, Mahak Singhal, Varun Venkataramani, Marc Cicero Schubert, Daniel Hinze, Michael Hudecek, Iris Helfrich, Dirk Schadendorf, Stefan W Schneider, Dana Westphal, Hellmut G Augustin, Jacky G Goetz, Yannick Schwab, Wolfgang Wick, Frank Winkler
Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization. Cancer research (2023)
Lavinia Arseni, Rakesh Sharma, Norman Mack, Deepthi Nagalla, Sibylle Ohl, Thomas Hielscher, Mahak Singhal, Robert Pilz, Hellmut G Augustin, Roger Sandhoff, Christel Herold-Mende, Björn Tews, Peter Lichter, Martina Seiffert
Sphingosine-1-Phosphate Recruits Macrophages and Microglia and Induces a Pro-Tumorigenic Phenotype That Favors Glioma Progression. Cancers 15 (2) (2023)
Stephanie F Preuß, Denise Grieshober, Hellmut G Augustin
Systemic Reprogramming of Endothelial Cell Signaling in Metastasis and Cachexia. Physiology (Bethesda, Md.) 38 (4) (2023)
Hellmut G Augustin, Gou Young Koh
Antiangiogenesis: Vessel Regression, Vessel Normalization, or Both? Cancer research 82 (1) (2022)
Nathalie Tisch, Carolin Mogler, Ana Stojanovic, Robert Luck, Emilia A Korhonen, Alexander Ellerkmann, Heike Adler, Mahak Singhal, Géza Schermann, Lena Erkert, Jay V Patankar, Andromachi Karakatsani, Anna-Lena Scherr, Yaron Fuchs, Adelheid Cerwenka, Stefan Wirtz, Bruno Christian Köhler, Hellmut G Augustin, Christoph Becker, Thomas Schmidt, Carmen Ruiz de Almodóvar
Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice. EMBO molecular medicine 14 (6) (2022)
Corinne Hübers, Ashik Ahmed Abdul Pari, Denise Grieshober, Martin Petkov, Alexander Schmidt, Tatjana Messmer, Christian Moritz Heyer, Sebastian Schölch, Stephanie S Kapel, Nicolas Gengenbacher, Mahak Singhal, Benjamin Schieb, Claudine Fricke, Rainer Will, Kim Remans, Jochen Sven Utikal, Christoph Reissfelder, Matthias Schlesner, Kairbaan M Hodivala-Dilke, Sander Kersten, Sergij Goerdt, Hellmut G Augustin, Felcht Moritz
Primary tumor-derived systemic nANGPTL4 inhibits metastasis. The Journal of experimental medicine 220 (1) (2022)
Hao He, Wu Yang, Nan Su, Chuankai Zhang, Jianing Dai, Feng Han, Mahak Singhal, Wenjuan Bai, Xiaolan Zhu, Jing Zhu, Zhen Liu, Wencheng Xia, Xiaoting Liu, Chonghe Zhang, Kai Jiang, Wenhui Huang, Dan Chen, Zhaoyin Wang, Xueyang He, Frank Kirchhoff, Zhenyu Li, Cong Liu, Jingning Huan, Xiaohong Wang, Wu Wei, Jing Wang, Hellmut G Augustin, Junhao Hu
Activating NO-sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury. The Journal of experimental medicine 220 (2) (2022)
Moritz Jakab, Till Rostalski, Ki Hong Lee, Carolin Mogler, Hellmut G Augustin
Tie2 Receptor in Tumor-Infiltrating Macrophages Is Dispensable for Tumor Angiogenesis and Tumor Relapse after Chemotherapy. Cancer research 82 (7) (2022)
Philipp-Sebastian Koch, Ki Hong Lee, Sergij Goerdt, Hellmut G Augustin
Angiodiversity and organotypic functions of sinusoidal endothelial cells. Angiogenesis 24 (2) (2021)
Mahak Singhal, Nicolas Gengenbacher, Ashik Ahmed Abdul Pari, Miki Kamiyama, Ling Hai, Bianca J Kuhn, David M Kallenberg, Shubhada R Kulkarni, Carlotta Camilli, Stephanie F Preuß, Barbara Leuchs, Carolin Mogler, Elisa Espinet, Eva Besemfelder, Danijela Heide, Mathias F Heikenwälder, Martin R Sprick, Flavia Carla Meotti, Jeroen Krijgsveld, Matthias Schlesner, Junhao Hu, Stephen E Moss, John Greenwood, Hellmut G Augustin
Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis. Science translational medicine 13 (609) (2021)
Ying Shen, Xiaohong Wang, Yi Liu, Mahak Singhal, Can Gürkaşlar, Aida Freire Valls, Yi Lei, Wenjie Hu, Géza Schermann, Heike Adler, Fa-Xing Yu, Tamas Fischer, Yi Zhu, Hellmut G Augustin, Thomas Schmidt, Carmen Ruiz de Almodóvar
STAT3-YAP/TAZ signaling in endothelial cells promotes tumor angiogenesis. Science signaling 14 (712) (2021)
Vincenza Cifarelli, Sila Appak-Baskoy, Vivek S Peche, Andrew Kluzak, Trevor Shew, Ramkumar Narendran, Kathryn M Pietka, Marina Cella, Curtis W Walls, Rafael S Czepielewski, Stoyan Ivanov, Gwendalyn J Randolph, Hellmut G Augustin, Nada A Abumrad
Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells. Nature communications 12 (1) (2021)
Dominik Pfister, Nicolás Gonzalo Nuñez, Roser Pinyol, Olivier Govaere, Matthias Pinter, Marta Szydlowska, Revant Gupta, Mengjie Qiu, Aleksandra Deczkowska, Assaf Weiner, Florian Müller, Ankit Sinha, Ekaterina Friebel, Thomas Engleitner, Daniela Lenggenhager, Anja Moncsek, Danijela Heide, Kristin Stirm, Jan Kosla, Eleni Kotsiliti, Valentina Leone, Michael Dudek, Suhail Yousuf, Donato Inverso, Indrabahadur Singh, Ana Teijeiro, Florian Castet, Carla Montironi, Philipp K Haber, Dina Tiniakos, Pierre Bedossa, Simon Cockell, Ramy Younes, Michele Vacca, Fabio Marra, Jörn M Schattenberg, Michael E D Allison, Elisabetta Bugianesi, Vlad Ratziu, Tiziana Pressiani, Antonio D'Alessio, Nicola Personeni, Lorenza Rimassa, Ann K Daly, Bernhard Scheiner, Katharina Pomej, Martha M Kirstein, Arndt Vogel, Markus Peck-Radosavljevic, Florian Hucke, Fabian Finkelmeier, Oliver Waidmann, Jörg Trojan, Kornelius Schulze, Henning Wege, Sandra Koch, Arndt Weinmann, Marco Bueter, Fabian Rössler, Alexander Siebenhüner, Sara De Dosso, Jan Philipp Mallm, Viktor Umansky, Manfred Jugold, Tom Luedde, Andrea Schietinger, Peter Schirmacher, Brinda Emu, Hellmut G Augustin, Adrian Billeter, Beat Müller-Stich, Hiroto Kikuchi, Dan G Duda, Fabian Kütting, Dirk-Thomas Waldschmidt, Matthias Philip Ebert, Nuh Rahbari, Henrik E Mei, Axel Ronald Schulz, Jane A McKeating, Nisar Malek, Stephan Spahn, Michael Bitzer, Marina Ruiz de Galarreta, Amaia Lujambio, Jean-François Dufour, Thomas U Marron, Ahmed Kaseb, Masatoshi Kudo, Yi-Hsiang Huang, Nabil Djouder, Katharina Wolter, Lars Zender, Parice N Marche, Thomas Decaens, David James Pinato, Roland Rad, Joachim C Mertens, Achim Weber, Kristian Unger, Rüdiger Klein, Susanne Roth, Zuzana Macek Jilkova, Manfred Claassen, Quentin M Anstee, Bjørt K Kragesteen, Percy A Knolle, Burkhard Becher, Josep M Llovet, Mathias F Heikenwälder
NASH limits anti-tumour surveillance in immunotherapy-treated HCC. Nature 592 (7854) (2021)
Miki Kamiyama, Hellmut G Augustin
Alternatively Spliced Form of Angiopoietin-2 as a New Vascular Rheostat. Cancer research 81 (1) (2021)
Haristi Gaitantzi, Julius Karch, Lena Germann, Chen Cai, Vanessa Rausch, Emrullah Birgin, Nuh Rahbari, Tatjana Seitz, Claus Hellerbrand, Courtney König, Hellmut G Augustin, Carolin Mogler, Carolina de la Torre, Norbert Gretz, Timo Itzel, Andreas Teufel, Matthias P A Ebert, Katja Breitkopf-Heinlein
BMP-9 Modulates the Hepatic Responses to LPS. Cells 9 (3) (2020)
Ashik Ahmed Abdul Pari, Mahak Singhal, Corinne Hübers, Carolin Mogler, Benjamin Schieb, Anja Gampp, Nicolas Gengenbacher, Louise E Reynolds, Dorothee Terhardt, Cyrill Géraud, Jochen Utikal, Markus Thomas, Sergij Goerdt, Kairbaan M Hodivala-Dilke, Hellmut G Augustin, Moritz Felcht
Tumor Cell-Derived Angiopoietin-2 Promotes Metastasis in Melanoma. Cancer research 80 (12) (2020)
Moritz Jakab, Hellmut G Augustin
Understanding angiodiversity: insights from single cell biology. Development (Cambridge, England) 147 (15) (2020)
Mahak Singhal, Nicolas Gengenbacher, Silvia La Porta, Stephanie Gehrs, Jingjing Shi, Miki Kamiyama, Diane M Bodenmiller, Anthony Fischl, Benjamin Schieb, Eva Besemfelder, Sudhakar Chintharlapalli, Hellmut G Augustin
Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody. EMBO molecular medicine 12 (6) (2020)
Nicolas Gengenbacher, Mahak Singhal, Carolin Mogler, Ling Hai, Laura Milde, Ashik Ahmed Abdul Pari, Eva Besemfelder, Claudine Fricke, Daniel Baumann, Stephanie Gehrs, Jochen Sven Utikal, Moritz Felcht, Junhao Hu, Matthias Schlesner, Rienk Offringa, Sudhakar R Chintharlapalli, Hellmut G Augustin
Timed Ang2-Targeted Therapy Identifies the Angiopoietin-Tie Pathway as Key Regulator of Fatal Lymphogenous Metastasis. Cancer discovery 11 (2) (2020)
Aida Freire Valls, Karl Knipper, Evangelia Giannakouri, Víctor Sarachaga, Sascha Hinterkopf, Michael Wuehrl, Ying Shen, Praveenkumar Radhakrishnan, Johannes Klose, Alexis Ulrich, Martin Schneider, Hellmut G Augustin, Carmen Ruiz de Almodovar, Thomas Schmidt
VEGFR1+ Metastasis-Associated Macrophages Contribute to Metastatic Angiogenesis and Influence Colorectal Cancer Patient Outcome. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (18) (2019)
Jaeryung Kim, Jang Ryul Park, Jeongwoon Choi, Intae Park, Yoonha Hwang, Hosung Bae, Yongjoo Kim, WooJhon Choi, Jee Myung Yang, Sangyeul Han, Tae-Young Chung, Pilhan Kim, Yoshiaki Kubota, Hellmut G Augustin, Wang-Yuhl Oh, Gou Young Koh
Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration. Science advances 5 (2) (2019)
Mahak Singhal, Hellmut G Augustin
Beyond Angiogenesis: Exploiting Angiocrine Factors to Restrict Tumor Progression and Metastasis. Cancer research 80 (4) (2019)
Mahak Singhal, Xiaoting Liu, Donato Inverso, Kai Jiang, Jianing Dai, Hao He, Susanne Bartels, Weiping Li, Ashik Ahmed Abdul Pari, Nicolas Gengenbacher, Eva Besemfelder, Lijian Hui, Hellmut G Augustin, Junhao Hu
Endothelial cell fitness dictates the source of regenerating liver vasculature. The Journal of experimental medicine 215 (10) (2018)
Katharina Schlereth, Dieter Weichenhan, Tobias Bauer, Tina Heumann, Evangelia Giannakouri, Daniel B Lipka, Samira Jaeger, Matthias Schlesner, Patrick Aloy, Roland Eils, Christoph Plass, Hellmut G Augustin
The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium. eLife 7 (2018)
Carolin Mogler, Courtney König, Matthias Wieland, Anja Runge, Eva Besemfelder, Dorde Komljenovic, Thomas Longerich, Peter Schirmacher, Hellmut G Augustin
Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin. EMBO molecular medicine 9 (6) (2018)
Hellmut G Augustin, Gou Young Koh
Organotypic vasculature: From descriptive heterogeneity to functional pathophysiology. Science (New York, N.Y.) 357 (6353) (2017)
Alessandro Fantin, Anastasia Lampropoulou, Valentina Senatore, James T Brash, Claudia Prahst, Clemens A Lange, Sidath E Liyanage, Claudio Raimondi, James W Bainbridge, Hellmut G Augustin, Christiana Ruhrberg
VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation. The Journal of experimental medicine 214 (4) (2017)
Do Young Park, Junyeop Lee, Jaeryung Kim, Kangsan Kim, Seonpyo Hong, Sangyeul Han, Yoshiaki Kubota, Hellmut G Augustin, Lei Ding, Jin Woo Kim, Hail Kim, Yulong He, Ralf H Adams, Gou Young Koh
Plastic roles of pericytes in the blood-retinal barrier. Nature communications 8 (2017)
Martin Teichert, Laura Milde, Annegret Holm, Laura Stanicek, Nicolas Gengenbacher, Soniya Savant, Tina Ruckdeschel, Zulfiyya Hasanov, Kshitij Srivastava, Junhao Hu, Stella Hertel, Arne Bartol, Katharina Schlereth, Hellmut G Augustin
Pericyte-expressed Tie2 controls angiogenesis and vessel maturation. Nature communications 8 (2017)

Hellmut G Augustin.css-eqlu8i{font-size:small;padding-left:4px;} (Hellmut Augustin)

Publication Activity (10 Years)

Top Topics

Top Venues

Hellmut G Augustin (Hellmut Augustin)