Isaac B Hilton

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 10

Top Venues

Nature biotechnology

Nature methods

IEEE open journal of engineering in medicine and biology

Science advances

Rice University

University of North Carolina at Chapel Hill (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Rice University Jan 01 2018

United States

Assistant Professor :: Biogengineering

Education History

University of North Carolina at Chapel Hill

United States

PHD :: Genetics and Molecular Biology

University of Missouri Columbia

United States

BSC :: Biological Sciences

Publications

Shankar Subramaniam, Metin Akay, Mark A Anastasio, Vasudev Bailey, David A Boas, Ashutosh Chilkoti, Jennifer R Cochran, Vicki L Colvin, Tejal A Desai, James S Duncan, Frederick H Epstein, Stephanie I Fraley, Cecilia Maria Giachelli, Kathryn Jane Grande-Allen, Jordan J Green, Xiang-Dong Edward Guo, Isaac B Hilton, Jay D Humphrey, Chris R Johnson, George Em Karniadakis, Michael R King, Robert F Kirsch, Sanjay Kumar, Cato T Laurencin, Song Li, Richard L Lieber, Nigel H Lovell, Prashant Mali, Stephanie A Pasquesi, David F Meaney, Brenda M Ogle, Bernhard O Palsson, Nicholas A Peppas, Eric J Perreault, Richard D Rabbitt, Lori A Setton, Lonnie D Shea, Sanjeev G Shroff, Kirk Shung, Andreas Savas Tolias, Marjolein C H van der Meulen, Shyni Varghese, Gordana Vunjak-Novakovic, John A White, Raimond L Winslow, Jianyi Jay Zhang, Kun Zhang, Charles Zukoski
Grand Challenges at the Interface of Engineering and Medicine. IEEE open journal of engineering in medicine and biology 5 (2024)
Barun Mahata, Alan Cabrera, Daniel A Brenner, Rosa Selenia Guerra-Resendez, Jing Li, Jacob Goell, Kaiyuan Wang, Yannie Guo, Mario Escobar, Abinand Krishna Parthasarathy, Hailey Szadowski, Guy Bedford, Daniel R Reed, Sunghwan Kim, Isaac B Hilton
Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control. Nature methods (2023)
Sanjit Singh Batra, Alan Cabrera, Jeffrey P Spence, Isaac B Hilton, Yun S Song
Predicting the effect of CRISPR-Cas9-based epigenome editing. bioRxiv : the preprint server for biology (2023)
Caleb J Bashor, Isaac B Hilton, Hozefa Bandukwala, Devyn M Smith, Omid Veiseh
Engineering the next generation of cell-based therapeutics. Nature reviews. Drug discovery 21 (9) (2022)
Kaiyuan Wang, Mario Escobar, Jing Li, Barun Mahata, Jacob Goell, Spencer Shah, Madeleine Cluck, Isaac B Hilton
Systematic comparison of CRISPR-based transcriptional activators uncovers gene-regulatory features of enhancer-promoter interactions. Nucleic acids research 50 (14) (2022)
Mario Escobar, Jing Li, Aditi Patel, Shizhe Liu, Qi Xu, Isaac B Hilton
Quantification of Genome Editing and Transcriptional Control Capabilities Reveals Hierarchies among Diverse CRISPR/Cas Systems in Human Cells. ACS synthetic biology 11 (10) (2022)
Matthew P Gemberling, Keith Siklenka, Erica Rodriguez, Katherine R Tonn-Eisinger, Alejandro Barrera, Fang Liu, Ariel Kantor, Liqing Li, Valentina Cigliola, Mariah F Hazlett, Courtney A Williams, Luke C Bartelt, Victoria J Madigan, Josephine C Bodle, Heather Daniels, Douglas C Rouse, Isaac B Hilton, Aravind Asokan, Maria Ciofani, Kenneth D Poss, Timothy E Reddy, Anne E West, Charles A Gersbach
Transgenic mice for in vivo epigenome editing with CRISPR-based systems. Nature methods 18 (8) (2021)
Jing Li, Barun Mahata, Mario Escobar, Jacob Goell, Kaiyuan Wang, Pranav Khemka, Isaac B Hilton
Programmable human histone phosphorylation and gene activation using a CRISPR/Cas9-based chromatin kinase. Nature communications 12 (1) (2021)
Sangsin Lee, Ning Ding, Yi-Di Sun, Tanglong Yuan, Jing Li, Qichen Yuan, Lizhong Liu, Jie Yang, Qian Wang, Anatoly B Kolomeisky, Isaac B Hilton, Erwei Zuo, Xue Gao
Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects. Science advances 6 (29) (2020)
Tyler S Klann, Joshua B Black, Malathi Chellappan, Alexias Safi, Lingyun Song, Isaac B Hilton, Gregory E Crawford, Timothy E Reddy, Charles A Gersbach
CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome. Nature biotechnology 35 (6) (2017)
Isaac B Hilton, Anthony M D'Ippolito, Christopher M Vockley, Pratiksha I Thakore, Gregory E Crawford, Timothy E Reddy, Charles A Gersbach
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Nature biotechnology 33 (5) (2015)

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Publication Activity (10 Years)

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Isaac B Hilton