Timothy E Reddy (Timothy Reddy)

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 30

Top Topics

Dna Methylation

Clinical Practice

Histone Deacetylase

Top Venues

Nature communications

Nature biotechnology

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Schuyler M Melore, Marisa C Hamilton, Timothy E Reddy
HyperCas12a enables highly-multiplexed epigenome editing screens. bioRxiv : the preprint server for biology (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
Schuyler M Melore, Marisa C Hamilton, Timothy E Reddy
HyperCas12a enables highly-multiplexed epigenome editing screens. bioRxiv : the preprint server for biology (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
Xue Zou, Zachary W Gomez, Timothy E Reddy, Andrew S Allen, William H Majoros
Bayesian Estimation of Allele-Specific Expression in the Presence of Phasing Uncertainty. bioRxiv : the preprint server for biology (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
David Yao, Josh Tycko, Jin Woo Oh, Lexi R Bounds, Sager J Gosai, Lazaros Lataniotis, Ava Mackay Smith, Benjamin R Doughty, Aditi K Narayanan, Henri Schmidt, Tania Guerrero-Altamirano, Keith Siklenka, Katherine Guo, Alexander D White, Ingrid Youngworth, Kalina Andreeva, Xingjie Ren, Alejandro Barrera, Yunhai Luo, Galip Gürkan Yardımcı, Ryan Tewhey, Anshul Kundaje, William J Greenleaf, Pardis C Sabeti, Christina S Leslie, Yuri Pritykin, Jill E Moore, Michael A Beer, Charles A Gersbach, Timothy E Reddy, Yin Shen, Jesse M Engreitz, Michael C Bassik, Steven K Reilly
Multicenter integrated analysis of noncoding CRISPRi screens. Nature methods 21 (4) (2024)
Eunchong Park, William E Barclay, Alejandro Barrera, Tzu-Chieh Liao, Harmony R Salzler, Timothy E Reddy, Mari L Shinohara, Maria Ciofani
Integrin α3 promotes T H 17 cell polarization and extravasation during autoimmune neuroinflammation. Science immunology 8 (88) (2023)
Sean R McCutcheon, Adam M Swartz, Michael C Brown, Alejandro Barrera, Christian McRoberts Amador, Keith Siklenka, Lucas L Humayun, Maria A Ter Weele, James M Isaacs, Timothy E Reddy, Andrew S Allen, Smita K Nair, Scott J Antonia, Charles A Gersbach
Transcriptional and epigenetic regulators of human CD8 + T cell function identified through orthogonal CRISPR screens. Nature genetics (2023)
Matthew P Gemberling, Keith Siklenka, Erica Rodriguez, Katherine R Tonn-Eisinger, Alejandro Barrera, Fang Liu, Ariel Kantor, Liqing Li, Valentina Cigliola, Mariah F Hazlett, Courtney A Williams, Luke C Bartelt, Victoria J Madigan, Josephine C Bodle, Heather Daniels, Douglas C Rouse, Isaac B Hilton, Aravind Asokan, Maria Ciofani, Kenneth D Poss, Timothy E Reddy, Anne E West, Charles A Gersbach
Transgenic mice for in vivo epigenome editing with CRISPR-based systems. Nature methods 18 (8) (2021)
Stefan Prekovic, Karianne Schuurman, Isabel Mayayo-Peralta, Anna G Manjón, Mark Buijs, Selçuk Yavuz, Max D Wellenstein, Alejandro Barrera, Kim Monkhorst, Anne Huber, Ben Morris, Cor Lieftink, Theofilos Chalkiadakis, Ferhat Alkan, Joana Silva, Balázs Győrffy, Liesbeth Hoekman, Bram van den Broek, Hans Teunissen, Donna O Debets, Tesa Severson, Jos Jonkers, Timothy E Reddy, Karin E de Visser, William James Faller, Roderick L Beijersbergen, Maarten Altelaar, Elzo de Wit, Rene Medema, Wilbert Zwart
Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer. Nature communications 12 (1) (2021)
Jonathan Hsijing Lu, Bianca Dumitrascu, Ian C McDowell, Brian Jo, Alejandro Barrera, Linda K Hong, Sarah M Leichter, Timothy E Reddy, Barbara Elizabeth Engelhardt
Causal network inference from gene transcriptional time-series response to glucocorticoids. PLoS computational biology 17 (1) (2021)
Noboru J Sakabe, Ivy Aneas, Nicholas Knoblauch, Débora R Sobreira, Nicole Clark, Cristina Paz, Cynthia Horth, Ryan Ziffra, Harjot Kaur, Xiao Liu, Rebecca Anderson, Jean Morrison, Virginia C Cheung, Chad A Grotegut, Timothy E Reddy, Bo Jacobson, Mikko Hallman, Kari Teramo, Amy Murtha, John A Kessler, William Grobman, Ge Zhang, Louis J Muglia, Sarosh Rana, Vincent J Lynch, Gregory E Crawford, Carole Ober, Xin He, Marcelo Aguiar Nobrega
Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth. Science advances 6 (49) (2020)
Adrian Pickar-Oliver, Joshua B Black, Mae M Lewis, Kevin J Mutchnick, Tyler S Klann, Kylie A Gilcrest, Madeleine J Sitton, Christopher E Nelson, Alejandro Barrera, Luke C Bartelt, Timothy E Reddy, Chase L Beisel, Rodolphe Barrangou, Charles A Gersbach
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells. Nature biotechnology 37 (12) (2019)
Julien Bryois, Melanie E Garrett, Lingyun Song, Alexias Safi, Paola Giusti-Rodriguez, Graham D Johnson, Annie W Shieh, Alfonso Buil, John F Fullard, Panagiotis Roussos, Pamela Sklar, Schahram Akbarian, Vahram Haroutunian, Craig A Stockmeier, Gregory A Wray, Kevin P White, Chunyu Liu, Timothy E Reddy, Allison Ashley-Koch, Patrick F Sullivan, Gregory E Crawford
Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia. Nature communications 9 (1) (2018)
Amanda J Lea, Christopher M Vockley, Rachel A Johnston, Christina A Del Carpio, Luis B Barreiro, Timothy E Reddy, Jenny Tung
Genome-wide quantification of the effects of DNA methylation on human gene regulation. eLife 7 (2018)
Graham D Johnson, Alejandro Barrera, Ian C McDowell, Anthony M D'Ippolito, William H Majoros, Christopher M Vockley, Xingyan Wang, Andrew S Allen, Timothy E Reddy
Human genome-wide measurement of drug-responsive regulatory activity. Nature communications 9 (1) (2018)
Tyler S Klann, Joshua B Black, Malathi Chellappan, Alexias Safi, Lingyun Song, Isaac B Hilton, Gregory E Crawford, Timothy E Reddy, Charles A Gersbach
CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome. Nature biotechnology 35 (6) (2017)
Isaac B Hilton, Anthony M D'Ippolito, Christopher M Vockley, Pratiksha I Thakore, Gregory E Crawford, Timothy E Reddy, Charles A Gersbach
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Nature biotechnology 33 (5) (2015)
David G Ousterout, Ami M Kabadi, Pratiksha I Thakore, William H Majoros, Timothy E Reddy, Charles A Gersbach
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy. Nature communications 6 (2015)