William C Hahn

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 70

Top Topics

Top Venues

Nature communications

Science signaling

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Karuna Mittal, Garrett W Cooper, Benjamin P Lee, Yongdong Su, Katie T Skinner, Jenny Shim, Hunter C Jonus, Won Jun Kim, Mihir Doshi, Diego Almanza, Bryan D Kynnap, Amanda L Christie, Xiaoping Yang, Glenn S Cowley, Brittaney A Leeper, Christopher L Morton, Bhakti Dwivedi, Taylor Lawrence, Manali Rupji, Paula Keskula, Stephanie Meyer, Catherine M Clinton, Manoj K Bhasin, Brian D Crompton, Yuen-Yi Tseng, Jesse S Boehm, Keith L Ligon, David E Root, Andrew Jackson Murphy, David M Weinstock, Prafulla C Gokhale, Jennifer M Spangle, Miguel N Rivera, Elizabeth A Mullen, Kimberly Stegmaier, Kelly C Goldsmith, William C Hahn, Andrew L Hong
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin. Communications biology 7 (1) (2024)
Karuna Mittal, Garrett W Cooper, Benjamin P Lee, Yongdong Su, Katie T Skinner, Jenny Shim, Hunter C Jonus, Won Jun Kim, Mihir Doshi, Diego Almanza, Bryan D Kynnap, Amanda L Christie, Xiaoping Yang, Glenn S Cowley, Brittaney A Leeper, Christopher L Morton, Bhakti Dwivedi, Taylor Lawrence, Manali Rupji, Paula Keskula, Stephanie Meyer, Catherine M Clinton, Manoj K Bhasin, Brian D Crompton, Yuen-Yi Tseng, Jesse S Boehm, Keith L Ligon, David E Root, Andrew Jackson Murphy, David M Weinstock, Prafulla C Gokhale, Jennifer M Spangle, Miguel N Rivera, Elizabeth A Mullen, Kimberly Stegmaier, Kelly C Goldsmith, William C Hahn, Andrew L Hong
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin. Communications biology 7 (1) (2024)
Karuna Mittal, Garrett W Cooper, Benjamin P Lee, Yongdong Su, Katie T Skinner, Jenny Shim, Hunter C Jonus, Won Jun Kim, Mihir Doshi, Diego Almanza, Bryan D Kynnap, Amanda L Christie, Xiaoping Yang, Glenn S Cowley, Brittaney A Leeper, Christopher L Morton, Bhakti Dwivedi, Taylor Lawrence, Manali Rupji, Paula Keskula, Stephanie Meyer, Catherine M Clinton, Manoj K Bhasin, Brian D Crompton, Yuen-Yi Tseng, Jesse S Boehm, Keith L Ligon, David E Root, Andrew Jackson Murphy, David M Weinstock, Prafulla C Gokhale, Jennifer M Spangle, Miguel N Rivera, Elizabeth A Mullen, Kimberly Stegmaier, Kelly C Goldsmith, William C Hahn, Andrew L Hong
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin. Communications biology 7 (1) (2024)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer. Cancer research 83 (4) (2023)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Pratyusha Bala, Jonathan P Rennhack, Daulet Aitymbayev, Clare Morris, Sydney M Moyer, Gina N Duronio, Paul Doan, Zhixin Li, Xiaoyan Liang, Jason L Hornick, Matthew B Yurgelun, William C Hahn, Nilay S Sethi
Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation. Science advances 9 (13) (2023)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas. Cancer discovery 13 (3) (2023)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Ricardo de Matos Simoes, Ryosuke Shirasaki, Sondra L Downey-Kopyscinski, Geoffrey M Matthews, Benjamin G Barwick, Vilas A Gupta, Daphné Dupéré-Richer, Shizuka Yamano, Yiguo Hu, Michal Sheffer, Eugen Dhimolea, Olga Dashevsky, Sara Gandolfi, Kazuya Ishiguro, Robin M Meyers, Jordan G Bryan, Neekesh V Dharia, Paul J Hengeveld, Johanna B Brüggenthies, Huihui Tang, Andrew J Aguirre, Quinlan L Sievers, Benjamin L Ebert, Brian J Glassner, Christopher J Ott, James E Bradner, Nicholas P Kwiatkowski, Daniel Auclair, Joan Levy, Jonathan J Keats, Richard W J Groen, Nathanael S Gray, Aedin C Culhane, James M McFarland, Joshua M Dempster, Jonathan D Licht, Lawrence H Boise, William C Hahn, Francisca Vazquez, Aviad Tsherniak, Constantine S Mitsiades
Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias. Nature cancer 4 (5) (2023)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas. Cancer discovery 13 (3) (2023)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer. Cancer research 83 (4) (2023)
Pratyusha Bala, Jonathan P Rennhack, Daulet Aitymbayev, Clare Morris, Sydney M Moyer, Gina N Duronio, Paul Doan, Zhixin Li, Xiaoyan Liang, Jason L Hornick, Matthew B Yurgelun, William C Hahn, Nilay S Sethi
Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation. Science advances 9 (13) (2023)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas. Cancer discovery 13 (3) (2023)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Pratyusha Bala, Jonathan P Rennhack, Daulet Aitymbayev, Clare Morris, Sydney M Moyer, Gina N Duronio, Paul Doan, Zhixin Li, Xiaoyan Liang, Jason L Hornick, Matthew B Yurgelun, William C Hahn, Nilay S Sethi
Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation. Science advances 9 (13) (2023)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer. Cancer research 83 (4) (2023)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer. Cancer research 83 (4) (2023)
Antje Schaefer, Richard G Hodge, Haisheng Zhang, G Aaron Hobbs, Julien Dilly, Minh V Huynh, Craig M Goodwin, Feifei Zhang, J Nathaniel Diehl, Mariaelena Pierobon, Elisa Baldelli, Sehrish Javaid, Karson Guthrie, Naim U Rashid, Emanuel F Petricoin, Adrienne D Cox, William C Hahn, Andrew J Aguirre, Adam J Bass, Channing J Der
RHOA L57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science signaling 16 (816) (2023)
Tanaz Sharifnia, Mathias J Wawer, Amy Goodale, Yenarae Lee, Mariya Kazachkova, Joshua M Dempster, Sandrine Muller, Joan Levy, Daniel M Freed, Josh Sommer, Jérémie Kalfon, Francisca Vazquez, William C Hahn, David E Root, Paul A Clemons, Stuart L Schreiber
Mapping the landscape of genetic dependencies in chordoma. Nature communications 14 (1) (2023)
Justin H Hwang, Rand Arafeh, Ji-Heui Seo, Sylvan C Baca, Megan Ludwig, Taylor E Arnoff, Lydia Sawyer, Camden Richter, Sydney Tape, Hannah E Bergom, Sean T McSweeney, Jonathan P Rennhack, Sarah A Klingenberg, Alexander T M Cheung, Jason Kwon, Jonathan So, Steven Kregel, Eliezer M Van Allen, Justin M Drake, Matthew L Freedman, William C Hahn
CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies. eLife 11 (2022)
Hugh S Gannon, Tao Zou, Michael K Kiessling, Galen F Gao, Diana Cai, Peter S Choi, Alexandru P Ivan, Ilana Buchumenski, Ashton C Berger, Jonathan T Goldstein, Andrew D Cherniak, Francisca Vazquez, Aviad Tsherniak, Erez Y Levanon, William C Hahn, Matthew L Meyerson
Author Correction: Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells. Nature communications 13 (1) (2022)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A ubiquitination cascade regulating the integrated stress response and survival in carcinomas. Cancer discovery (2022)
Oana Ursu, James T Neal, Emily K Shea, Pratiksha I Thakore, Livnat Jerby, Lan Nguyen, Danielle Dionne, Celeste Diaz, Julia Bauman, Mariam Mounir Mosaad, Christian Fagre, April Lo, Maria McSharry, Andrew O Giacomelli, Seav Huong Ly, Orit Rozenblatt-Rosen, William C Hahn, Andrew J Aguirre, Alice H Berger, Aviv Regev, Jesse S Boehm
Massively parallel phenotyping of coding variants in cancer with Perturb-seq. Nature biotechnology 40 (6) (2022)
Bärbel Schröfelbauer, Patrick K Kimes, Paige Hauke, Charlotte E Reid, Kevin Shao, Sarah J Hill, Rafael Irizarry, William C Hahn
Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Hannah L Williams, Andressa Dias Costa, Jinming Zhang, Srivatsan Raghavan, Peter S Winter, Kevin S Kapner, Scott P Ginebaugh, Sara A Väyrynen, Juha P Väyrynen, Chen Yuan, Andrew W Navia, Junning Wang, Annan Yang, Timothy L Bosse, Radha L Kalekar, Kristen E Lowder, Mai Chan Lau, Dalia Elganainy, Vicente Morales-Oyarvide, Douglas A Rubinson, Harshabad Singh, Kimberley J Perez, James M Cleary, Thomas E Clancy, Jiping Wang, Joseph D Mancias, Lauren K Brais, Emma R Hill, Margaret M Kozak, David C Linehan, Richard F Dunne, Daniel T Chang, Albert C Koong, Aram F Hezel, William C Hahn, Alex K Shalek, Andrew J Aguirre, Jonathan Andrew Nowak, Brian M Wolpin
Spatially-resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intra-tumoral heterogeneity. Cancer research (2022)
Bärbel Schröfelbauer, Patrick K Kimes, Paige Hauke, Charlotte E Reid, Kevin Shao, Sarah J Hill, Rafael Irizarry, William C Hahn
Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic interrogation of tumor cell resistance to CAR T cell therapy in pancreatic cancer. Cancer research (2022)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic interrogation of tumor cell resistance to CAR T cell therapy in pancreatic cancer. Cancer research (2022)
Bärbel Schröfelbauer, Patrick K Kimes, Paige Hauke, Charlotte E Reid, Kevin Shao, Sarah J Hill, Rafael Irizarry, William C Hahn
Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Bärbel Schröfelbauer, Patrick K Kimes, Paige Hauke, Charlotte E Reid, Kevin Shao, Sarah J Hill, Rafael Irizarry, William C Hahn
Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Jason J Kwon, Behnoush Hajian, Xiang-Qun Sean Xie, Lucy C Young, Alvaro J Amor, James R Fuller, Cara V Fraley, Abbey M Sykes, Jonathan So, Joshua Pan, Laura Baker, Sun Joo Lee, Douglas B Wheeler, David L Mayhew, Nicole S Persky, Xiaoping Yang, David E Root, Anthony M Barsotti, Andrew W Stamford, Charles K Perry, Alex Burgin, Frank McCormick, Christopher T Lemke, William C Hahn, Andrew J Aguirre
Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex. Nature 609 (7926) (2022)
Bärbel Schröfelbauer, Patrick K Kimes, Paige Hauke, Charlotte E Reid, Kevin Shao, Sarah J Hill, Rafael Irizarry, William C Hahn
Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Daniel P Bondeson, Brenton R Paolella, Adhana Asfaw, Michael V Rothberg, Thomas A Skipper, Carly Langan, Gabriel Mesa, Alfredo Gonzalez, Lauren E Surface, Kentaro Ito, Mariya Kazachkova, William N Colgan, Allison Warren, Joshua M Dempster, John Michael Krill-Burger, Maria Ericsson, Andrew A Tang, Iris Fung, Emily S Chambers, Mai Abdusamad, Nancy Dumont, John G Doench, Federica Piccioni, David E Root, Jesse S Boehm, William C Hahn, Michael Mannstadt, James M McFarland, Francisca Vazquez, Todd R Golub
Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer. Nature cancer 3 (6) (2022)
Allison Warren, Yejia Chen, Andrew Jones, Tsukasa Shibue, William C Hahn, Jesse S Boehm, Francisca Vazquez, Aviad Tsherniak, James M McFarland
Global computational alignment of tumor and cell line transcriptional profiles. Nature communications 12 (1) (2021)
Jason J Kwon, William C Hahn
A Leucine-Rich Repeat Protein Provides a SHOC2 the RAS Circuit: a Structure-Function Perspective. Molecular and cellular biology 41 (4) (2021)
James M Cleary, Srivatsan Raghavan, Qibiao Wu, Yvonne Y Li, Liam F Spurr, Hersh V Gupta, Douglas A Rubinson, Isobel J Fetter, Jason L Hornick, Jonathan A Nowak, Giulia Siravegna, Lipika Goyal, Lei Shi, Lauren K Brais, Maureen Loftus, Atul B Shinagare, Thomas A Abrams, Thomas E Clancy, Jiping Wang, Anuj K Patel, Franck Brichory, Anne Vaslin Chessex, Ryan J Sullivan, Rachel B Keller, Sarah Denning, Emma R Hill, Geoffrey I Shapiro, Anna Pokorska-Bocci, Claudio Zanna, Kimmie Ng, Deborah Schrag, Pasi A Jänne, William C Hahn, Andrew D Cherniack, Ryan B Corcoran, Matthew Meyerson, Antoine Daina, Vincent Zoete, Nabeel Bardeesy, Brian M Wolpin
FGFR2 Extracellular Domain In-Frame Deletions Are Therapeutically Targetable Genomic Alterations That Function as Oncogenic Drivers in Cholangiocarcinoma. Cancer discovery 11 (10) (2021)
Sylvan C Baca, David Y Takeda, Ji-Heui Seo, Justin Hwang, Sheng Yu Ku, Rand Arafeh, Taylor Arnoff, Supreet Agarwal, Connor Bell, Edward O'Connor, Xintao Qiu, Sarah Abou Alaiwi, Rosario I Corona, Marcos A S Fonseca, Claudia Giambartolomei, Paloma Cejas, Klothilda Lim, Monica He, Anjali Sheahan, Amin H Nassar, Jacob E Berchuck, Lisha Brown, Holly M Nguyen, Ilsa M Coleman, Arja Kaipainen, Navonil De Sarkar, Peter S Nelson, Colm Morrissey, Keegan Korthauer, Mark M Pomerantz, Leigh Ellis, Bogdan Pasaniuc, Kate Lawrenson, Kathleen Kelly, Amina Zoubeidi, William C Hahn, Himisha Beltran, Henry W Long, Myles Brown, Eva Corey, Matthew L Freedman
Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer. Nature communications 12 (1) (2021)
Haitham A Elmarakeby, Justin H Hwang, Rand Arafeh, Jett Crowdis, Sydney Gang, David Liu, Saud H AlDubayan, Keyan Salari, Steven Kregel, Camden Richter, Taylor E Arnoff, Jihye Park, William C Hahn, Eliezer Van Allen
Biologically informed deep neural network for prostate cancer discovery. Nature 598 (7880) (2021)
Neekesh V Dharia, Guillaume Kugener, Lillian M Guenther, Clare F Malone, Adam D Durbin, Andrew L Hong, Thomas P Howard, Pratiti Bandopadhayay, Caroline S Wechsler, Iris Fung, Allison C Warren, Joshua M Dempster, John Michael Krill-Burger, Brenton R Paolella, Phoebe Moh, Nishant Jha, Andrew Tang, Phillip G Montgomery, Jesse S Boehm, William C Hahn, Charles W M Roberts, James M McFarland, Aviad Tsherniak, Todd R Golub, Francisca Vazquez, Kimberly Stegmaier
A first-generation pediatric cancer dependency map. Nature genetics 53 (4) (2021)
Nathan J Schauer, Xiaoxi Liu, Robert S Magin, Laura M Doherty, Wai Cheung Chan, Scott B Ficarro, Wanyi Hu, Rebekka M Roberts, Roxana E Iacob, Björn Stolte, Andrew O Giacomelli, Sumner Perera, Kyle McKay, Sarah A Boswell, Ellen L Weisberg, Arghya Ray, Dharminder Chauhan, Sirano Dhe-Paganon, Ken C Anderson, James D Griffin, Jianing Li, William C Hahn, Peter Karl Sorger, John R Engen, Kimberly Stegmaier, Jarrod A Marto, Sara J Buhrlage
Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism. Scientific reports 10 (1) (2020)
Thomas P Howard, Elaine M Oberlick, Matthew G Rees, Taylor E Arnoff, Minh-Tam Pham, Lisa Brenan, Mariana DoCarmo, Andrew L Hong, Guillaume Kugener, Hsien-Chao Chou, Yiannis Drosos, Kaeli M Mathias, Pilar Ramos, Brinton Seashore-Ludlow, Andrew O Giacomelli, Xiaofeng Wang, Burgess B Freeman, Kaley Blankenship, Lauren Hoffmann, Hong L Tiv, Prafulla C Gokhale, Cory M Johannessen, Elizabeth A Stewart, Stuart L Schreiber, William C Hahn, Charles W M Roberts
Rhabdoid Tumors Are Sensitive to the Protein-Translation Inhibitor Homoharringtonine. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (18) (2020)
Steffen Boettcher, Peter Grant Miller, Rohan Sharma, Marie McConkey, Matthew Joseph Leventhal, Andrei V Krivtsov, Andrew O Giacomelli, Waihay J Wong, Jesi Kim, Sherry Chao, Kari J Kurppa, Xiaoping Yang, Kirsten Milenkowic, Frederica Piccioni, David E Root, Frank G Rücker, Yael Flamand, Donna S Neuberg, R Coleman Lindsley, Pasi A Jänne, William C Hahn, Tyler Jacks, Hartmut Döhner, Scott A Armstrong, Benjamin L Ebert
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies. Science (New York, N.Y.) 365 (6453) (2020)
Fleur M Ferguson, Behnam Nabet, Srivatsan Raghavan, Yan Liu, Alan L Leggett, Miljan Kuljanin, Radha L Kalekar, Annan Yang, Shuning He, Jinhua Wang, Raymond W S Ng, Rita Sulahian, Lianbo Li, Emily J Poulin, Ling Huang, Jost Koren, Nora Dieguez-Martinez, Sergio Espinosa, Zhiyang Zeng, Cesear R Corona, James D Vasta, Ryoma Ohi, Taebo Sim, Nam Doo Kim, Wayne Harshbarger, Jose Miguel Lizcano, Matthew B Robers, Senthil Muthaswamy, Charles Y Lin, A Thomas Look, Kevin M Haigis, Joseph D Mancias, Brian M Wolpin, Andrew J Aguirre, William C Hahn, Kenneth D Westover, Nathanael S Gray
Discovery of a selective inhibitor of doublecortin like kinase 1. Nature chemical biology 16 (6) (2020)
Jong Wook Kim, Christian Berrios, Miju Kim, Amy E Schade, Guillaume Adelmant, Huwate Yeerna, Emily Damato, Amanda Balboni Iniguez, Laurence Florens, Michael P Washburn, Kim Stegmaier, Nathanael S Gray, Pablo Tamayo, Ole Gjoerup, Jarrod A Marto, James DeCaprio, William C Hahn
STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells. eLife 9 (2020)
Haoxin Li, Shaoyang Ning, Mahmoud Ghandi, Gregory V Kryukov, Shuba Gopal, Amy Deik, Amanda Souza, Kerry Pierce, Paula Keskula, Desiree Hernandez, Julie Ann, Dojna Shkoza, Verena Apfel, Yilong Zou, Francisca Vazquez, Jordi Barretina, Raymond A Pagliarini, Giorgio G Galli, David E Root, William C Hahn, Aviad Tsherniak, Marios Giannakis, Stuart L Schreiber, Andrew T Chan, Levi A Garraway, William R Sellers
The landscape of cancer cell line metabolism. Nature medicine 25 (5) (2019)
Pratiti Bandopadhayay, Frederica Piccioni, Ryan O'Rourke, Patricia Ho, Elizabeth M Gonzalez, Graham Buchan, Kenin Qian, Gabrielle Gionet, Emily Girard, Margo Coxon, Matthew G Rees, Lisa Brenan, Frank Dubois, Ofer Shapira, Noah F Greenwald, Melanie Pages, Amanda Balboni Iniguez, Brenton R Paolella, Alice Meng, Claire Sinai, Giovanni Roti, Neekesh V Dharia, Amanda Creech, Benjamin Tanenbaum, Prasidda Khadka, Adam Tracy, Hong L Tiv, Andrew L Hong, Shannon Coy, Rumana Rashid, Jia-Ren Lin, Glenn S Cowley, Fred C Lam, Amy Goodale, Yenarae Lee, Kathleen Schoolcraft, Francisca Vazquez, William C Hahn, Aviad Tsherniak, James E Bradner, Michael B Yaffe, Till Milde, Stefan M Pfister, Jun Qi, Monica Schenone, Steven A Carr, Keith L Ligon, Mark W Kieran, Sandro Santagata, James M Olson, Prafulla C Gokhale, Jacob D Jaffe, David E Root, Kimberly Stegmaier, Cory M Johannessen, Rameen Beroukhim
Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma. Nature communications 10 (1) (2019)
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