Jan Korabecny (Jan Korábečný)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 33

Top Topics

Molecular Docking

Posttraumatic Stress Disorder

Blood Brain Barrier

Top Venues

Molecules (Basel, Switzerland)

Archives of toxicology

Journal of enzyme inhibition and medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Filip Pidany, Jana Kroustkova, Jaroslav Jenco, Katerina Hradiska Breiterova, Lubica Muckova, Lucie Cahlíková, Jiri Kunes, Jakub Fibigar, Tomas Kucera, Martin Novak, Ales Sorf, Martina Hrabinova, Lenka Pulkrabkova, Jiri Janousek, Ondrej Soukup, Daniel Jun, Jan Korabecny
Carltonine-derived compounds for targeted butyrylcholinesterase inhibition. RSC medicinal chemistry 15 (5) (2024)
Filip Pidany, Jana Kroustkova, Jaroslav Jenco, Katerina Hradiska Breiterova, Lubica Muckova, Lucie Cahlíková, Jiri Kunes, Jakub Fibigar, Tomas Kucera, Martin Novak, Ales Sorf, Martina Hrabinova, Lenka Pulkrabkova, Jiri Janousek, Ondrej Soukup, Daniel Jun, Jan Korabecny
Carltonine-derived compounds for targeted butyrylcholinesterase inhibition. RSC medicinal chemistry 15 (5) (2024)
Barbora Svobodova, Lenka Pulkrabkova, Dawid Panek, Anna Misiachna, Marharyta Kolcheva, Rudolf Andrys, Jiri Handl, Jan Capek, Pavlina Nyvltova, Tomas Rousar, Lukas Prchal, Vendula Hepnarova, Martina Hrabinova, Lubica Múčková, Daniela Tosnerova, Galina Karabanovich, Vladimir Finger, Ondrej Soukup, Martin Horak, Jan Korabecny
Structure-Guided Design of N -Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease. International journal of molecular sciences 24 (11) (2023)
Jakub Opravil, Jaroslav Pejchal, Vladimir Finger, Jan Korabecny, Tomas Rozsypal, Martina Hrabinová, Lubica Múčková, Vendula Hepnarova, Jan Konecny, Ondrej Soukup, Daniel Jun
A-agents, misleadingly known as "Novichoks": a narrative review. Archives of toxicology (2023)
Martin Novak, Marie Vajrychova, Stefania Koutsilieri, Despoina-Christina Sismanoglou, Tereza Kobrlova, Lukas Prchal, Barbora Svobodova, Jan Korabecny, Tomas Zarybnicky, Lucie Raisova-Stuchlikova, Lenka Skalova, Volker Martin Lauschke, Radim Kučera, Ondrej Soukup
Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation. ACS chemical biology (2023)
Radomir Juza, Kamil Musilek, Eva Mezeiova, Ondrej Soukup, Jan Korabecny
Recent advances in dopamine D 2 receptor ligands in the treatment of neuropsychiatric disorders. Medicinal research reviews 43 (1) (2022)
Ondrej Soukup, Jan Korabecny
Chemical and Biological Threats, Hazard Potential and Countermeasures. Toxics 10 (8) (2022)
Lenka Pulkrabkova, Barbora Svobodova, Jan Konecny, Tereza Kobrlova, Lubica Muckova, Jiri Janousek, Jaroslav Pejchal, Jan Korabecny, Ondrej Soukup
Neurotoxicity evoked by organophosphates and available countermeasures. Archives of toxicology (2022)
Galina F Makhaeva, Nadezhda V Kovaleva, Natalia P Boltneva, Elena V Rudakova, Sofya V Lushchekina, Tatiana Yu Astakhova, Igor V Serkov, Alexey N Proshin, Eugene V Radchenko, Vladimir A Palyulin, Jan Korabecny, Ondrej Soukup, Sergey O Bachurin, Rudy J Richardson
Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N -Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile. Molecules (Basel, Switzerland) 27 (3) (2022)
Viriyanata Wijaya, Ondřej Janďourek, Jana Křoustková, Kateřina Hradiská Breiterová, Jan Korabecny, Kateřina Sobolová, Eliška Kohelová, Anna Hošťálková, Klára Konečná, Marcela Šafratová, Rudolf Vrabec, Jiří Kuneš, Lubomír Opletal, Jakub Chlebek, Lucie Cahlíková
Alkaloids of Dicranostigma franchetianum (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents. Biomolecules 12 (6) (2022)
Jan Korabecny, Ondrej Soukup
Cholinesterase Research. Biomolecules 11 (8) (2021)
Monika Hudáčová, Slavka Hamulakova, Eva Žilecká, Rastislav Jendzelovsky, Jana Vargová, Juraj Ševc, Peter Fedoročko, Ondrej Soukup, Jana Janočková, Veronika Ihnatova, Tomas Kucera, Petr Bzonek, Nikola Novakova, Daniel Jun, Lucie Junova, Jan Korabecny, Teodorico C Ramalho, Maria Kozurkova
Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells. International journal of molecular sciences 22 (8) (2021)
Abdullah Al Mamun, Filip Pidaný, Daniela Hulcová, Jana Maříková, Tomas Kucera, Monika Schmidt, Maria Carmen Catapano, Martina Hrabinová, Daniel Jun, Lubica Múčková, Jiří Kuneš, Jiří Janoušek, Rudolf Andrýs, Lucie Nováková, Rozálie Peřinová, Negar Maafi, Ondrej Soukup, Jan Korabecny, Lucie Cahlíková
Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies. International journal of molecular sciences 22 (15) (2021)
Radomir Juza, Kristyna Stefkova, Wim Dehaen, Alena Randakova, Tomas Petrasek, Iveta Vojtěchová, Tereza Kobrlova, Lenka Pulkrabkova, Lubica Múčková, Marko Mecava, Lukas Prchal, Eva Mezeiova, Kamil Musilek, Ondrej Soukup, Jan Korabecny
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole. Biomolecules 11 (9) (2021)
Lukas Gorecki, Vendula Hepnarova, Jana Zdarova Karasova, Martina Hrabinova, Charlotte Courageux, José Dias, Tomas Kucera, Tereza Kobrlova, Lubica Muckova, Lukas Prchal, David Malinak, Daniel Jun, Kamil Musilek, Franz Worek, Florian Nachon, Ondrej Soukup, Jan Korabecny
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase. Archives of toxicology 95 (3) (2021)
Yitian Zhou, Gabriel Herras Arribas, Ainoleena Turku, Tuuli Jürgenson, Souren Mkrtchian, Kristi Krebs, Yi Wang, Barbora Svobodova, Lili A Milani, Gunnar Schulte, Jan Korabecny, Stefano Gastaldello, Volker Martin Lauschke
Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine. Science advances 7 (36) (2021)
Lukáš Górecki, Martin Andrs, Jan Korabecny
Clinical Candidates Targeting the ATR-CHK1-WEE1 Axis in Cancer. Cancers 13 (4) (2021)
Lukáš Górecki, Elisa Uliassi, Manuela Bartolini, Jana Janockova, Martina Hrabinova, Vendula Hepnarova, Lukas Prchal, Lubica Muckova, Jaroslav Pejchal, Jana Z Karasova, Eva Mezeiova, Marketa Benkova, Tereza Kobrlova, Ondrej Soukup, Sabrina Petralla, Barbara Monti, Jan Korabecny, Maria Laura Bolognesi
Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease. ACS chemical neuroscience 12 (9) (2021)
Radomir Juza, Přemysl Vlček, Eva Mezeiova, Kamil Musilek, Ondrej Soukup, Jan Korabecny
Recent advances with 5-HT3 modulators for neuropsychiatric and gastrointestinal disorders. Medicinal research reviews 40 (5) (2020)
Jana Maříková, Aneta Ritomská, Jan Korabecny, Rozálie Peřinová, Abdullah Al Mamun, Tomas Kucera, Eliška Kohelová, Daniela Hulcová, Tereza Kobrlová, Jiří Kuneš, Lucie Nováková, Lucie Cahlíková
Aromatic Esters of the Crinane Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Butyrylcholinesterase. Journal of natural products 83 (5) (2020)
Jana Hroudová, Tereza Nováková, Jan Korabecny, David Malinak, Lukáš Górecki, Zdeněk Fišar
Effects of Novel Tacrine Derivatives on Mitochondrial Energy Metabolism and Monoamine Oxidase Activity-In Vitro Study. Molecular neurobiology 58 (3) (2020)
David Malinak, Rafael Dolezal, Vendula Hepnarova, Miroslava Hozova, Rudolf Andrys, Petr Bzonek, Veronika Racakova, Jan Korabecny, Lukáš Górecki, Eva Mezeiova, Miroslav Psotka, Daniel Jun, Teodorico C Ramalho, Kamil Musilek
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators. Journal of enzyme inhibition and medicinal chemistry 35 (1) (2020)
Abdullah Al Mamun, Jana Maříková, Daniela Hulcová, Jiří Janoušek, Marcela Šafratová, Lucie Nováková, Tomáš Kučera, Martina Hrabinová, Jiří Kuneš, Jan Korabecny, Lucie Cahlíková
Amaryllidaceae Alkaloids of Belladine-Type from Narcissus pseudonarcissus cv. Carlton as New Selective Inhibitors of Butyrylcholinesterase. Biomolecules 10 (5) (2020)
Jakub Chlebek, Jan Korabecny, Rafael Doležal, Sarka Stepankova, Daniel I Pérez, Anna Hošťálková, Lubomír Opletal, Lucie Cahlíková, Kateřina Macáková, Tomas Kucera, Martina Hrabinová, Daniel Jun
In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier. Molecules (Basel, Switzerland) 24 (7) (2019)
Galina Karabanovich, Jan Dušek, Karin Savková, Oto Pavliš, Ivona Pávková, Jan Korabecny, Tomáš Kučera, Hana Kočová Vlčková, Stanislav Huszár, Zuzana Konyariková, Klára Konečná, Ondřej Jand'ourek, Jiřina Stolaříková, Jana Korduláková, Kateřina Vávrová, Petr Pávek, Věra Klimešová, Alexandr Hrabálek, Katarína Mikušová, Jaroslav Roh
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase. Journal of medicinal chemistry 62 (17) (2019)
Barbora Svobodova, Eva Mezeiova, Vendula Hepnarova, Martina Hrabinová, Lubica Múčková, Tereza Kobrlova, Daniel Jun, Ondrej Soukup, María Luisa Jimeno, José Marco-Contelles, Jan Korabecny
Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors. Biomolecules 9 (8) (2019)
Eliška Kohelová, Rozálie Peřinová, Negar Maafi, Jan Korabecny, Daniela Hulcová, Jana Maříková, Tomas Kucera, Loreto Martínez González, Martina Hrabinova, Katarina Vorčáková, Lucie Nováková, Angela De Simone, Radim Havelek, Lucie Cahlíková
Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease. Molecules (Basel, Switzerland) 24 (7) (2019)
Jana Janockova, Jan Korabecny, Jana Plsikova, Katerina Babkova, Eva Konkolova, Dana Kucerova, Jana Vargova, Jan Koval, Rastislav Jendzelovsky, Peter Fedorocko, Jana Kasparkova, Viktor Brabec, Jan Rosocha, Ondrej Soukup, Slavka Hamulakova, Kamil Kuca, Mária Kozurkova
In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers. Journal of enzyme inhibition and medicinal chemistry 34 (1) (2019)
Srishti Sharma, Namrata Singh, Eugenie Nepovimova, Jan Korabecny, Kamil Kuca, Manmohan L Satnami, Kallol K Ghosh
Interaction of synthesized nitrogen enriched graphene quantum dots with novel anti-Alzheimer's drugs: spectroscopic insights. Journal of biomolecular structure & dynamics 38 (6) (2019)
Eva Mezeiova, Katarina Chalupova, Eugenie Nepovimova, Lukáš Górecki, Ondrej Soukup, Rafael Dolezal, David Malinak, Jana Janockova, Daniel Jun, Teodorico C Ramalho, Jan Korabecny
Profiling donepezil template into multipotent hybrids with antioxidant properties. Journal of enzyme inhibition and medicinal chemistry 33 (1) (2018)
Jana Janockova, Rafael Dolezal, Eugenie Nepovimova, Tereza Kobrlova, Marketa Benkova, Teodorico C Ramalho, Jan Konecny, Eva Mezeiova, Michaela Melikova, Vendula Hepnarova, Avi Ring, Ondrej Soukup, Jan Korabecny
Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods. Molecules (Basel, Switzerland) 23 (11) (2018)
Lukas Gorecki, Ondrej Soukup, Tomas Kucera, David Malinak, Daniel Jun, Kamil Kuca, Kamil Musilek, Jan Korabecny
Oxime K203: a drug candidate for the treatment of tabun intoxication. Archives of toxicology 93 (3) (2018)
Federica Prati, Christian Bergamini, Romana Fato, Ondrej Soukup, Jan Korabecny, Vincenza Andrisano, Manuela Bartolini, Maria Laura Bolognesi
Novel 8-Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer's Disease. ChemMedChem 11 (12) (2016)