Samuel H Gellman

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 56

Top Topics

Clostridium Difficile

Respiratory Syncytial Virus

Top Venues

Journal of the American Chemical Society

The journal of physical chemistry. B

ACS chemical biology

Chembiochem : a European journal of chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Shi Liu, Eileen J Daley, Lauren My-Linh Tran, Zhen Yu, Monica Reyes, Thomas Dean, Ashok Khatri, Paul M Levine, Aaron T Balana, Matthew R Pratt, Harald Jüppner, Samuel H Gellman, Thomas J Gardella
Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants. Journal of the American Chemical Society 146 (10) (2024)
Shi Liu, Eileen J Daley, Lauren My-Linh Tran, Zhen Yu, Monica Reyes, Thomas Dean, Ashok Khatri, Paul M Levine, Aaron T Balana, Matthew R Pratt, Harald Jüppner, Samuel H Gellman, Thomas J Gardella
Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants. Journal of the American Chemical Society 146 (10) (2024)
Shi Liu, Eileen J Daley, Lauren My-Linh Tran, Zhen Yu, Monica Reyes, Thomas Dean, Ashok Khatri, Paul M Levine, Aaron T Balana, Matthew R Pratt, Harald Jüppner, Samuel H Gellman, Thomas J Gardella
Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants. Journal of the American Chemical Society (2024)
Ilona C Unarta, Siqin Cao, Eshani C Goonetilleke, Jiani Niu, Samuel H Gellman, Xuhui Huang
Submillisecond Atomistic Molecular Dynamics Simulations Reveal Hydrogen Bond-Driven Diffusion of a Guest Peptide in Protein-RNA Condensate. The journal of physical chemistry. B 128 (10) (2024)
Shi Liu, Eileen J Daley, Lauren My-Linh Tran, Zhen Yu, Monica Reyes, Thomas Dean, Ashok Khatri, Paul M Levine, Aaron T Balana, Matthew R Pratt, Harald Jüppner, Samuel H Gellman, Thomas J Gardella
Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants. Journal of the American Chemical Society (2024)
Shi Liu, Eileen J Daley, Lauren My-Linh Tran, Zhen Yu, Monica Reyes, Thomas Dean, Ashok Khatri, Paul M Levine, Aaron T Balana, Matthew R Pratt, Harald Jüppner, Samuel H Gellman, Thomas J Gardella
Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants. Journal of the American Chemical Society 146 (10) (2024)
Ilona C Unarta, Siqin Cao, Eshani C Goonetilleke, Jiani Niu, Samuel H Gellman, Xuhui Huang
Submillisecond Atomistic Molecular Dynamics Simulations Reveal Hydrogen Bond-Driven Diffusion of a Guest Peptide in Protein-RNA Condensate. The journal of physical chemistry. B 128 (10) (2024)
Shi Liu, Eileen J Daley, Lauren My-Linh Tran, Zhen Yu, Monica Reyes, Thomas Dean, Ashok Khatri, Paul M Levine, Aaron T Balana, Matthew R Pratt, Harald Jüppner, Samuel H Gellman, Thomas J Gardella
Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants. Journal of the American Chemical Society 146 (10) (2024)
Ilona C Unarta, Siqin Cao, Eshani C Goonetilleke, Jiani Niu, Samuel H Gellman, Xuhui Huang
Submillisecond Atomistic Molecular Dynamics Simulations Reveal Hydrogen Bond-Driven Diffusion of a Guest Peptide in Protein-RNA Condensate. The journal of physical chemistry. B (2024)
Ilona C Unarta, Siqin Cao, Eshani C Goonetilleke, Jiani Niu, Samuel H Gellman, Xuhui Huang
Submillisecond Atomistic Molecular Dynamics Simulations Reveal Hydrogen Bond-Driven Diffusion of a Guest Peptide in Protein-RNA Condensate. The journal of physical chemistry. B 128 (10) (2024)
Shi Liu, Eileen J Daley, Lauren My-Linh Tran, Zhen Yu, Monica Reyes, Thomas Dean, Ashok Khatri, Paul M Levine, Aaron T Balana, Matthew R Pratt, Harald Jüppner, Samuel H Gellman, Thomas J Gardella
Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants. Journal of the American Chemical Society 146 (10) (2024)
Ilona C Unarta, Siqin Cao, Eshani C Goonetilleke, Jiani Niu, Samuel H Gellman, Xuhui Huang
Submillisecond Atomistic Molecular Dynamics Simulations Reveal Hydrogen Bond-Driven Diffusion of a Guest Peptide in Protein-RNA Condensate. The journal of physical chemistry. B 128 (10) (2024)
Ruslan Gibadullin, Brian P Cary, Samuel H Gellman
Differential Responses of the GLP-1 and GLP-2 Receptors to N-Terminal Modification of a Dual Agonist. Journal of the American Chemical Society (2023)
Ruslan Gibadullin, Rylie K Morris, Jiani Niu, John Sidney, Alessandro Sette, Samuel H Gellman
Thioamide Analogues of MHC I Antigen Peptides. Journal of the American Chemical Society (2023)
Ruslan Gibadullin, Tae Wook Kim, Lauren My-Linh Tran, Samuel H Gellman
Hormone Analogues with Unique Signaling Profiles from Replacement of α-Residue Triads with β/γ Diads. Journal of the American Chemical Society (2023)
Kyle A Brown, Rylie K Morris, Samantha J Eckhardt, Ying Ge, Samuel H Gellman
Phosphorylation Sites of the Gastric Inhibitory Polypeptide Receptor (GIPR) Revealed by Trapped-Ion-Mobility Spectrometry Coupled to Time-of-Flight Mass Spectrometry (TIMS-TOF MS). Journal of the American Chemical Society (2023)
Jiani Niu, Cindy Qiu, Nicholas L Abbott, Samuel H Gellman
Formation of versus Recruitment to RNA-Rich Condensates: Controlling Effects Exerted by Peptide Side Chain Identity. Journal of the American Chemical Society 144 (23) (2022)
Mary Katherine Andrews, Xinyu Liu, Samuel H Gellman
Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold. Journal of the American Chemical Society 144 (5) (2022)
Jiani Niu, Annika J Cederstrand, Geoffrey A Eddinger, Boyu Yin, James W Checco, Craig A Bingman, Victor K Outlaw, Samuel H Gellman
Trimer-to-Monomer Disruption Mechanism for a Potent, Protease-Resistant Antagonist of Tumor Necrosis Factor-α Signaling. Journal of the American Chemical Society 144 (22) (2022)
Zhen Yu, Brian P Cary, Tae Wook Kim, Kevin D Nguyen, Thomas J Gardella, Samuel H Gellman
Kinetic and Thermodynamic Insights into Agonist Interactions with the Parathyroid Hormone Receptor-1 from a New NanoBRET Assay. ACS chemical biology 17 (11) (2022)
Mary Katherine Andrews, Xinyu Liu, Samuel H Gellman
Correction to "Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold". Journal of the American Chemical Society 144 (34) (2022)
Shi Liu, Zhen Yu, Eileen J Daley, Craig A Bingman, Austin T Bruchs, Thomas J Gardella, Samuel H Gellman
Altered signaling at the PTH receptor via modified agonist contacts with the extracellular domain provides a path to prolonged agonism in vivo. Proceedings of the National Academy of Sciences of the United States of America 119 (48) (2022)
Yuxin Qian, Shuai Deng, Zihao Cong, Haodong Zhang, Ziyi Lu, Ning Shao, Sonia Abid Bhatti, Cong Zhou, Jiagao Cheng, Samuel H Gellman, Runhui Liu
Secondary Amine Pendant β-Peptide Polymers Displaying Potent Antibacterial Activity and Promising Therapeutic Potential in Treating MRSA-Induced Wound Infections and Keratitis. Journal of the American Chemical Society 144 (4) (2022)
Alex D White, Karina A Peña, Lisa J Clark, Christian Santa Maria, Shi Liu, Frédéric G Jean-Alphonse, Ji Young Lee, Saifei Lei, Zhiqiang Cheng, Chia-Ling Tu, Fei Fang, Nicholas Szeto, Thomas J Gardella, Kunhong Xiao, Samuel H Gellman, Ivet Bahar, Ieva Sutkeviciute, Wenhan Chang, Jean-Pierre Vilardaga
Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation. Science signaling 14 (703) (2021)
Adam F Kleman, Deseree L Dufek, Theodore L Fobe, Darrell R McCaslin, Brian P Cary, Michael R Shirts, Samuel H Gellman
Potential Foldamers Based on an ortho-Terphenyl Amino Acid. Organic letters 23 (12) (2021)
Chenxuan Wang, Naomi A Biok, Karthik Nayani, Xiaoguang Wang, Hongseung Yeon, Chi-Kuen Derek Ma, Samuel H Gellman, Nicholas L Abbott
Cationic Side Chain Identity Directs the Hydrophobically Driven Self-Assembly of Amphiphilic β-Peptides in Aqueous Solution. Langmuir : the ACS journal of surfaces and colloids 37 (11) (2021)
Rory D De Vries, Katharina S Schmitz, Francesca T Bovier, Camilla Predella, Jonathan Khao, Danny Noack, Bart L Haagmans, Sander Herfst, Kyle N Stearns, Jennifer Drew-Bear, Sudipta Biswas, Barry Rockx, Gael G McGill, N Valerio Dorrello, Samuel H Gellman, Christopher A Alabi, Rik L de Swart, Anne Moscona, Matteo Porotto
Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets. Science (New York, N.Y.) 371 (6536) (2021)
Brian P Cary, Giuseppe Deganutti, Peishen Zhao, Tin T Truong, Sarah J Piper, Xinyu Liu, Matthew J Belousoff, Radostin Danev, Patrick M Sexton, Denise Wootten, Samuel H Gellman
Structural and functional diversity among agonist-bound states of the GLP-1 receptor. Nature chemical biology 18 (3) (2021)
Ruslan Gibadullin, Caleb J Randall, John Sidney, Alessandro Sette, Samuel H Gellman
Backbone Modifications of HLA-A2-Restricted Antigens Induce Diverse Binding and T Cell Activation Outcomes. Journal of the American Chemical Society 143 (17) (2021)
Victor K Outlaw, Ross W Cheloha, Eric M Jurgens, Francesca T Bovier, Yun Zhu, Dale F Kreitler, Olivia Harder, Stefan Niewiesk, Matteo Porotto, Samuel H Gellman, Anne Moscona
Engineering Protease-Resistant Peptides to Inhibit Human Parainfluenza Viral Respiratory Infection. Journal of the American Chemical Society 143 (15) (2021)
Philip P Lampkin, Blaise J Thompson, Samuel H Gellman
Versatile Open-Source Photoreactor Architecture for Photocatalysis Across the Visible Spectrum. Organic letters 23 (13) (2021)
Lei Liu, Kevin C Courtney, Sean W Huth, Leslie A Rank, Bernard Weisblum, Edwin R Chapman, Samuel H Gellman
Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon-3 Polymers. Journal of the American Chemical Society 143 (8) (2021)
Joshua B Jones, Lei Liu, Leslie A Rank, Daniela Wetzel, Emily C Woods, Naomi Biok, Sarah E Anderson, Myung-Ryul Lee, Runhui Liu, Sean W Huth, Brindar K Sandhu, Samuel H Gellman, Shonna M McBride
Cationic Homopolymers Inhibit Spore and Vegetative Cell Growth of Clostridioides difficile. ACS infectious diseases 7 (5) (2021)
Xinyu Liu, Samuel H Gellman
Comparisons of β-Hairpin Propensity Among Peptides with Homochiral or Heterochiral Strands. Chembiochem : a European journal of chemical biology 22 (18) (2021)
Kathleen W Kurgan, Bifan Chen, Kyle A Brown, Paulo Falco Cobra, Xinyu Ye, Ying Ge, Samuel H Gellman
Stable Picodisc Assemblies from Saposin Proteins and Branched Detergents. Biochemistry 60 (14) (2021)
Zebediah C Girvin, Samuel H Gellman
Foldamer Catalysis. Journal of the American Chemical Society 142 (41) (2020)
James W Checco, Geoffrey A Eddinger, Nicholas J Rettko, Alexander R Chartier, Samuel H Gellman
Tumor Necrosis Factor-α Trimer Disassembly and Inactivation via Peptide-Small Molecule Synergy. ACS chemical biology 15 (8) (2020)
Zebediah C Girvin, Philip P Lampkin, Xinyu Liu, Samuel H Gellman
Catalytic Intramolecular Conjugate Additions of Aldehyde-Derived Enamines to α,β-Unsaturated Esters. Organic letters 22 (11) (2020)
Leslie A Rank, Anurag Agrawal, Lei Liu, Yanyu Zhu, Mainak Mustafi, James C Weisshaar, Samuel H Gellman
Diverse Impacts on Prokaryotic and Eukaryotic Membrane Activities from Hydrophobic Subunit Variation Among Nylon-3 Copolymers. ACS chemical biology 16 (1) (2020)
Victor K Outlaw, Jennifer T Lemke, Yun Zhu, Samuel H Gellman, Matteo Porotto, Anne Moscona
Structure-Guided Improvement of a Dual HPIV3/RSV Fusion Inhibitor. Journal of the American Chemical Society 142 (5) (2020)
Alex D White, Frédéric G Jean-Alphonse, Fei Fang, Karina A Peña, Shi Liu, Gabriele M König, Asuka Inoue, Despoina Aslanoglou, Samuel H Gellman, Evi Kostenis, Kunhong Xiao, Jean-Pierre Vilardaga
Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR. Proceedings of the National Academy of Sciences of the United States of America 117 (13) (2020)
Shi Liu, Samuel H Gellman
Preparation of β2-Homologous Amino Acids Bearing Polar Side Chains via a Collective Synthesis Strategy. The Journal of organic chemistry 85 (3) (2020)
Victor K Outlaw, Dale F Kreitler, Debora Stelitano, Matteo Porotto, Anne Moscona, Samuel H Gellman
Effects of Single α-to-β Residue Replacements on Recognition of an Extended Segment in a Viral Fusion Protein. ACS infectious diseases 6 (8) (2020)
Naomi A Biok, Alexander D Passow, Chenxuan Wang, Craig A Bingman, Nicholas L Abbott, Samuel H Gellman
Retention of Coiled-Coil Dimer Formation in the Absence of Ion Pairing at Positions Flanking the Hydrophobic Core. Biochemistry 58 (48) (2019)
Victor K Outlaw, Samantha Bottom-Tanzer, Dale F Kreitler, Samuel H Gellman, Matteo Porotto, Anne Moscona
Dual Inhibition of Human Parainfluenza Type 3 and Respiratory Syncytial Virus Infectivity with a Single Agent. Journal of the American Chemical Society 141 (32) (2019)
Dale F Kreitler, Zhihui Yao, Jay D Steinkruger, David E Mortenson, Lijun Huang, Ritesh Mittal, Benjamin R Travis, Katrina T Forest, Samuel H Gellman
A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation. Journal of the American Chemical Society 141 (4) (2019)
Kathleen W Kurgan, Adam F Kleman, Craig A Bingman, Dale F Kreitler, Bernard Weisblum, Katrina T Forest, Samuel H Gellman
Retention of Native Quaternary Structure in Racemic Melittin Crystals. Journal of the American Chemical Society 141 (19) (2019)
Brian P Cary, Marlies V Hager, Samuel H Gellman
Impact of Substitution Registry on the Receptor-Activation Profiles of Backbone-Modified Glucagon-like Peptide-1 Analogues. Chembiochem : a European journal of chemical biology 20 (22) (2019)
Ross W Cheloha, Andrew W Woodham, Djenet Bousbaine, Tong Wang, Shi Liu, John Sidney, Alessandro Sette, Samuel H Gellman, Hidde L Ploegh
Recognition of Class II MHC Peptide Ligands That Contain β-Amino Acids. Journal of immunology (Baltimore, Md. : 1950) 203 (6) (2019)
Zhihui Yao, Brian P Cary, Craig A Bingman, Chenxuan Wang, Dale F Kreitler, Kenneth A Satyshur, Katrina T Forest, Samuel H Gellman
Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin α3 Toxicity. Journal of the American Chemical Society 141 (19) (2019)
Shi Liu, Frederic G Jean-Alphonse, Alex D White, Denise Wootten, Patrick M Sexton, Thomas J Gardella, Jean-Pierre Vilardaga, Samuel H Gellman
Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism. Journal of the American Chemical Society 141 (37) (2019)
Zebediah C Girvin, Mary Katherine Andrews, Xinyu Liu, Samuel H Gellman
Foldamer-templated catalysis of macrocycle formation. Science (New York, N.Y.) 366 (6472) (2019)
Jiang Wang, Brian P Cary, Peyton D Beyer, Samuel H Gellman, Daniel J Weix
Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters. Angewandte Chemie (International ed. in English) 58 (35) (2019)
Shi Liu, Ross W Cheloha, Tomoyuki Watanabe, Thomas J Gardella, Samuel H Gellman
Receptor selectivity from minimal backbone modification of a polypeptide agonist. Proceedings of the National Academy of Sciences of the United States of America 115 (49) (2018)
Geoffrey A Eddinger, Samuel H Gellman
Differential Effects of β3 - versus β2 -Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3-Derived α/β-Peptides. Angewandte Chemie (International ed. in English) 57 (42) (2018)
James W Checco, Samuel H Gellman
Iterative Nonproteinogenic Residue Incorporation Yields α/β-Peptides with a Helix-Loop-Helix Tertiary Structure and High Affinity for VEGF. Chembiochem : a European journal of chemical biology 18 (3) (2017)