J Keith Joung

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 26

Top Topics

Transcription Factor

Induced Pluripotent Stem Cells

Top Venues

Nature biotechnology

Science (New York, N.Y.)

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Y Esther Tak, Jonathan Y Hsu, Justine Shih, Hayley T Schultz, Ivy T Nguyen, Kin Chung Lam, Luca Pinello, J Keith Joung
CRISPR PERSIST-On enables heritable and fine-tunable human gene activation. bioRxiv : the preprint server for biology (2024)
Jonathan Y Hsu, Kin Chung Lam, Justine Shih, Luca Pinello, J Keith Joung
MOSAIC enables in situ saturation mutagenesis of genes and CRISPR prime editing guide RNA optimization in human cells. bioRxiv : the preprint server for biology (2024)
Hui-Shan Li, Divya V Israni, Keith A Gagnon, Kok Ann Gan, Michael H Raymond, Jeffry D Sander, Kole T Roybal, J Keith Joung, Wilson W Wong, Ahmad S Khalil
Multidimensional control of therapeutic human cell function with synthetic gene circuits. Science (New York, N.Y.) 378 (6625) (2022)
Hui-Shan Li, Divya V Israni, Keith A Gagnon, Kok Ann Gan, Michael H Raymond, Jeffry D Sander, Kole T Roybal, J Keith Joung, Wilson W Wong, Ahmad S Khalil
Multidimensional control of therapeutic human cell function with synthetic gene circuits. Science (New York, N.Y.) 378 (6625) (2022)
Hui-Shan Li, Divya V Israni, Keith A Gagnon, Kok Ann Gan, Michael H Raymond, Jeffry D Sander, Kole T Roybal, J Keith Joung, Wilson W Wong, Ahmad S Khalil
Multidimensional control of therapeutic human cell function with synthetic gene circuits. Science (New York, N.Y.) 378 (6625) (2022)
Hui-Shan Li, Divya V Israni, Keith A Gagnon, Kok Ann Gan, Michael H Raymond, Jeffry D Sander, Kole T Roybal, J Keith Joung, Wilson W Wong, Ahmad S Khalil
Multidimensional control of therapeutic human cell function with synthetic gene circuits. Science (New York, N.Y.) 378 (6625) (2022)
Julian Grünewald, Bret R Miller, Regan N Szalay, Peter K Cabeceiras, Christopher J Woodilla, Eliza Jane B Holtz, Karl Petri, J Keith Joung
Engineered CRISPR prime editors with compact, untethered reverse transcriptases. Nature biotechnology (2022)
Hui-Shan Li, Divya V Israni, Keith A Gagnon, Kok Ann Gan, Michael H Raymond, Jeffry D Sander, Kole T Roybal, J Keith Joung, Wilson W Wong, Ahmad S Khalil
Multidimensional control of therapeutic human cell function with synthetic gene circuits. Science (New York, N.Y.) 378 (6625) (2022)
Hui-Shan Li, Divya V Israni, Keith A Gagnon, Kok Ann Gan, Michael H Raymond, Jeffry D Sander, Kole T Roybal, J Keith Joung, Wilson W Wong, Ahmad S Khalil
Multidimensional control of therapeutic human cell function with synthetic gene circuits. Science (New York, N.Y.) 378 (6625) (2022)
Jonathan Y Hsu, Julian Grünewald, Regan N Szalay, Justine Shih, Andrew V Anzalone, Kin Chung Lam, Max W Shen, Karl Petri, David R Liu, J Keith Joung, Luca Pinello
PrimeDesign software for rapid and simplified design of prime editing guide RNAs. Nature communications 12 (1) (2021)
Nikolay L Malinin, GaHyun Lee, Cicera R Lazzarotto, Yichao Li, Zongli Zheng, Nhu T Nguyen, Matthew Liebers, Ved V Topkar, A John Iafrate, Long P Le, Martin J Aryee, J Keith Joung, Shengdar Q Tsai
Defining genome-wide CRISPR-Cas genome-editing nuclease activity with GUIDE-seq. Nature protocols 16 (12) (2021)
Y Esther Tak, Joy E Horng, Nicholas T Perry, Hayley T Schultz, Sowmya Iyer, Qiuming Yao, Luli S Zou, Martin J Aryee, Luca Pinello, J Keith Joung
Augmenting and directing long-range CRISPR-mediated activation in human cells. Nature methods 18 (9) (2021)
Karl Petri, Weiting Zhang, Junyan Ma, Andrea Schmidts, Hyunho Lee, Joy E Horng, Daniel Y Kim, Ibrahim C Kurt, M Kendell Clement, Jonathan Y Hsu, Luca Pinello, Marcela V Maus, J Keith Joung, Jing-Ruey Joanna Yeh
CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells. Nature biotechnology (2021)
Karl Petri, Weiting Zhang, Junyan Ma, Andrea Schmidts, Hyunho Lee, Joy E Horng, Daniel Y Kim, Ibrahim C Kurt, M Kendell Clement, Jonathan Y Hsu, Luca Pinello, Marcela V Maus, J Keith Joung, Jing-Ruey Joanna Yeh
Author Correction: CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells. Nature biotechnology (2021)
William T Garrood, Nace Kranjc, Karl Petri, Daniel Y Kim, Jimmy A Guo, Andrew M Hammond, Ioanna Morianou, Vikram Pattanayak, J Keith Joung, Andrea Crisanti, Alekos Simoni
Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito. Proceedings of the National Academy of Sciences of the United States of America 118 (22) (2021)
Ibrahim C Kurt, Ronghao Zhou, Sowmya Iyer, Sara P Garcia, Bret R Miller, Lukas M Langner, Julian Grünewald, J Keith Joung
CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells. Nature biotechnology 39 (1) (2020)
Peter C DeWeirdt, Kendall R Sanson, Annabel K Sangree, Mudra Hegde, Ruth E Hanna, Marissa N Feeley, Audrey L Griffith, Teng Teng, Samantha M Borys, Christine Strand, J Keith Joung, Benjamin P Kleinstiver, Xuewen Pan, Alan Huang, John G Doench
Optimization of AsCas12a for combinatorial genetic screens in human cells. Nature biotechnology 39 (1) (2020)
Julian Grünewald, Ronghao Zhou, Caleb A Lareau, Sara P Garcia, Sowmya Iyer, Bret R Miller, Lukas M Langner, Jonathan Y Hsu, Martin J Aryee, J Keith Joung
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing. Nature biotechnology 38 (7) (2020)
Jonathan Y Hsu, Charles P Fulco, Mitchel A Cole, Matthew C Canver, Danilo Pellin, Falak Sher, Rick Farouni, Kendell Clement, Jimmy A Guo, Luca Biasco, Stuart H Orkin, Jesse M Engreitz, Eric S Lander, J Keith Joung, Daniel E Bauer, Luca Pinello
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data. Nature methods 15 (12) (2019)
Julian Grünewald, Ronghao Zhou, Sowmya Iyer, Caleb A Lareau, Sara P Garcia, Martin J Aryee, J Keith Joung
CRISPR DNA base editors with reduced RNA off-target and self-editing activities. Nature biotechnology 37 (9) (2019)
Killian S Hanlon, Benjamin P Kleinstiver, Sara P Garcia, Mikołaj Piotr Zaborowski, Adrienn Volak, Stefan E Spirig, Alissa Muller, Alexander A Sousa, Shengdar Q Tsai, Niclas E Bengtsson, Camilla Lööv, Martin Ingelsson, Jeffrey S Chamberlain, David P Corey, Martin J Aryee, J Keith Joung, Xandra O Breakefield, Casey A Maguire, Bence György
High levels of AAV vector integration into CRISPR-induced DNA breaks. Nature communications 10 (1) (2019)
Bence György, Carl Nist-Lund, Bifeng Pan, Yukako Asai, K Domenica Karavitaki, Benjamin P Kleinstiver, Sara P Garcia, Mikołaj P Zaborowski, Paola Solanes, Sofia Spataro, Bernard L Schneider, J Keith Joung, Gwenaëlle S G Géléoc, Jeffrey R Holt, David P Corey
Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss. Nature medicine 25 (7) (2019)
Kendell Clement, Holly Rees, Matthew C Canver, Jason M Gehrke, Rick Farouni, Jonathan Y Hsu, Mitchel A Cole, David R Liu, J Keith Joung, Daniel E Bauer, Luca Pinello
CRISPResso2 provides accurate and rapid genome editing sequence analysis. Nature biotechnology 37 (3) (2019)
Caleb A Lareau, M Kendell Clement, Jonathan Y Hsu, Vikram Pattanayak, J Keith Joung, Martin J Aryee, Luca Pinello
Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo". Nature methods 15 (4) (2018)
Jennifer Listgarten, Michael Weinstein, Benjamin P Kleinstiver, Alexander A Sousa, J Keith Joung, Jake Crawford, Kevin Gao, Luong Hoang, Melih Elibol, John G Doench, Nicolo Fusi
Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs. Nature biomedical engineering 2 (1) (2018)
Y Esther Tak, Benjamin P Kleinstiver, James K Nuñez, Jonathan Y Hsu, Joy E Horng, Jingyi Gong, Jonathan S Weissman, J Keith Joung
Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors. Nature methods 14 (12) (2017)