Jens Carlsson

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 25

Top Venues

Journal of medicinal chemistry

ACS chemical biology

Molecules (Basel, Switzerland)

Science advances

Uppsala University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Uppsala University Jul 01 2015

Sweden

Assistant Professor :: Dept. of Cell and Molecular Biology

Publications

Alejandro Díaz-Holguín, Marcus Saarinen, Duc Duy Vo, Andrea Sturchio, Niclas Branzell, Israel Cabeza de Vaca, Huabin Hu, Núria Mitjavila-Domènech, Annika Lindqvist, Pawel Baranczewski, Mark J Millan, Yunting Yang, Jens Carlsson, Per Svenningsson
AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1. Science advances 10 (32) (2024)
Filipe Areias, Carla Correia, Ashly Rocha, Sofia Teixeira, Marián Castro, Jose Brea, Huabin Hu, Jens Carlsson, Maria I Loza, Maria Fernanda Proença, M Alice Carvalho
2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives. Molecules (Basel, Switzerland) 29 (11) (2024)
Alejandro Díaz-Holguín, Marcus Saarinen, Duc Duy Vo, Andrea Sturchio, Niclas Branzell, Israel Cabeza de Vaca, Huabin Hu, Núria Mitjavila-Domènech, Annika Lindqvist, Pawel Baranczewski, Mark J Millan, Yunting Yang, Jens Carlsson, Per Svenningsson
AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1. Science advances 10 (32) (2024)
Filipe Areias, Carla Correia, Ashly Rocha, Sofia Teixeira, Marián Castro, Jose Brea, Huabin Hu, Jens Carlsson, Maria I Loza, Maria Fernanda Proença, M Alice Carvalho
2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives. Molecules (Basel, Switzerland) 29 (11) (2024)
Filipe Areias, Carla Correia, Ashly Rocha, Sofia Teixeira, Marián Castro, Jose Brea, Huabin Hu, Jens Carlsson, Maria I Loza, Maria Fernanda Proença, M Alice Carvalho
2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives. Molecules (Basel, Switzerland) 29 (11) (2024)
Albert Suades, Aziz Qureshi, Sarah E McComas, Mathieu Coinçon, Axel Rudling, Yurie Chatzikyriakidou, Michael Landreh, Jens Carlsson, David Drew
Establishing mammalian GLUT kinetics and lipid composition influences in a reconstituted-liposome system. Nature communications 14 (1) (2023)
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, Lisa Wissler, Richard J Lewis, Emma Danelius, Andreas Luttens, Pierre Matricon, Jens Carlsson, Stijn Lenders, Beate König, Anna Friedel, Peter Sjö, Stefan Schiesser, Jan Kihlberg
Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction". Journal of medicinal chemistry (2023)
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, Lisa Wissler, Richard J Lewis, Emma Danelius, Andreas Luttens, Pierre Matricon, Jens Carlsson, Stijn Lenders, Beate König, Anna Friedel, Peter Sjö, Stefan Schiesser, Jan Kihlberg
Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction". Journal of medicinal chemistry 66 (3) (2023)
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, Lisa Wissler, Richard J Lewis, Emma Danelius, Andreas Luttens, Pierre Matricon, Jens Carlsson, Stijn Lenders, Beate König, Anna Friedel, Peter Sjö, Stefan Schiesser, Jan Kihlberg
Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction". Journal of medicinal chemistry 66 (3) (2023)
Stefanie Kampen, David Rodríguez, Morten Jørgensen, Monika Kruszyk-Kujawa, Xinyan Huang, Michael Collins, Noel Boyle, Damien Maurel, Axel Rudling, Guillaume Lebon, Jens Carlsson
Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5. ACS chemical biology 17 (10) (2022)
Andreas Luttens, Hjalmar Gullberg, Eldar Abdurakhmanov, Duy Duc Vo, Dario Akaberi, Vladimir O Talibov, Natalia Nekhotiaeva, Laura Vangeel, Steven De Jonghe, Dirk Jochmans, Janina Krambrich, Ali Tas, Bo Lundgren, Ylva Gravenfors, Alexander J Craig, Yoseph Atilaw, Anja Sandström, Lindon W K Moodie, Åke Lundkvist, Martijn J van Hemert, Johan Neyts, Johan Lennerstrand, Jan Kihlberg, Kristian Sandberg, U Helena Danielson, Jens Carlsson
Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. Journal of the American Chemical Society 144 (7) (2022)
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, Lisa Wissler, Richard J Lewis, Emma Danelius, Andreas Luttens, Pierre Matricon, Jens Carlsson, Stijn Lenders, Beate König, Anna Friedel, Peter Sjö, Stefan Schiesser, Jan Kihlberg
Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction. Journal of medicinal chemistry 65 (4) (2022)
Jon Kapla, Ismael Rodríguez-Espigares, Flavio Ballante, Jana Selent, Jens Carlsson
Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models? PLoS computational biology 17 (5) (2021)
Pierre Matricon, Duc Duy Vo, Zhan-Guo Gao, Jan Kihlberg, Kenneth A Jacobson, Jens Carlsson
Fragment-based design of selective GPCR ligands guided by free energy simulations. Chemical communications (Cambridge, England) 57 (92) (2021)
Stefanie Kampen, Duc Duy Vo, Xiaoqun Zhang, Nicolas Panel, Yunting Yang, Mariama Jaiteh, Pierre Matricon, Per Svenningsson, Jose Brea, Maria Isabel Loza, Jan Kihlberg, Jens Carlsson
Structure-Guided Design of G-Protein-Coupled Receptor Polypharmacology. Angewandte Chemie (International ed. in English) 60 (33) (2021)
Oliver Fleetwood, Jens Carlsson, Lucie Delemotte
Identification of ligand-specific G protein-coupled receptor states and prediction of downstream efficacy via data-driven modeling. eLife 10 (2021)
Mariama Jaiteh, Ismael Rodríguez-Espigares, Jana Selent, Jens Carlsson
Performance of virtual screening against GPCR homology models: Impact of template selection and treatment of binding site plasticity. PLoS computational biology 16 (3) (2020)
Kenneth A Jacobson, Zhan-Guo Gao, Pierre Matricon, Matthew T Eddy, Jens Carlsson
Adenosine A2A receptor antagonists: from caffeine to selective non-xanthines. British journal of pharmacology (2020)
Flavio Ballante, Axel Rudling, Alexey Zeifman, Andreas Luttens, Duy Duc Vo, John J Irwin, Jan Kihlberg, Jose Brea, Maria Isabel Loza, Jens Carlsson
Docking Finds GPCR Ligands in Dark Chemical Matter. Journal of medicinal chemistry 63 (2) (2020)
Oliver Fleetwood, Pierre Matricon, Jens Carlsson, Lucie Delemotte
Energy Landscapes Reveal Agonist Control of G Protein-Coupled Receptor Activation via Microswitches. Biochemistry 59 (7) (2020)
Axel Rudling, Adolfo Orro, Jens Carlsson
Prediction of Ordered Water Molecules in Protein Binding Sites from Molecular Dynamics Simulations: The Impact of Ligand Binding on Hydration Networks. Journal of chemical information and modeling 58 (2) (2018)
Mariama Jaiteh, Alexey Zeifman, Marcus Saarinen, Per Svenningsson, Jose Bréa, Maria Isabel Loza, Jens Carlsson
Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson's Disease. Journal of medicinal chemistry 61 (12) (2018)
Axel Rudling, Robert Gustafsson, Ingrid Almlöf, Evert Homan, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark, Jens Carlsson
Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space. Journal of medicinal chemistry 60 (19) (2017)
Anirudh Ranganathan, Philipp Heine, Axel Rudling, Andreas Plückthun, Lutz Kummer, Jens Carlsson
Ligand Discovery for a Peptide-Binding GPCR by Structure-Based Screening of Fragment- and Lead-Like Chemical Libraries. ACS chemical biology 12 (3) (2017)
Barbara Männel, Mariama Jaiteh, Alexey Zeifman, Alena Randakova, Dorothee Möller, Harald Hübner, Peter Gmeiner, Jens Carlsson
Structure-Guided Screening for Functionally Selective D2 Dopamine Receptor Ligands from a Virtual Chemical Library. ACS chemical biology 12 (10) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jens Carlsson