Stefan Geschwindner (Göran Dahl)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 21

Top Topics

Molecular Dynamics Simulations

Angiotensin Converting Enzyme

Structure Activity Relationship

Top Venues

Journal of medicinal chemistry

bioRxiv : the preprint server for biology

SLAS discovery : advancing life sciences R & D

Expert opinion on drug discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Jared M Sampson, Daniel A Cannon, Jianxin Duan, Jordan C K Epstein, Alina P Sergeeva, Phinikoula S Katsamba, Seetha M Mannepalli, Fabiana A Bahna, Hélène Adihou, Stéphanie M Guéret, Ranganath Gopalakrishnan, Stefan Geschwindner, D Gareth Rees, Anna Sigurdardottir, Trevor Wilkinson, Roger B Dodd, Leonardo De Maria, Juan Carlos Mobarec, Lawrence Shapiro, Barry Honig, Andrew Buchanan, Richard A Friesner, Lingle Wang
Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculations. bioRxiv : the preprint server for biology (2024)
Jared M Sampson, Daniel A Cannon, Jianxin Duan, Jordan C K Epstein, Alina P Sergeeva, Phinikoula S Katsamba, Seetha M Mannepalli, Fabiana A Bahna, Hélène Adihou, Stéphanie M Guéret, Ranganath Gopalakrishnan, Stefan Geschwindner, D Gareth Rees, Anna Sigurdardottir, Trevor Wilkinson, Roger B Dodd, Leonardo De Maria, Juan Carlos Mobarec, Lawrence Shapiro, Barry Honig, Andrew Buchanan, Richard A Friesner, Lingle Wang
Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculations. bioRxiv : the preprint server for biology (2024)
Jared M Sampson, Daniel A Cannon, Jianxin Duan, Jordan C K Epstein, Alina P Sergeeva, Phinikoula S Katsamba, Seetha M Mannepalli, Fabiana A Bahna, Hélène Adihou, Stéphanie M Guéret, Ranganath Gopalakrishnan, Stefan Geschwindner, D Gareth Rees, Anna Sigurdardottir, Trevor Wilkinson, Roger B Dodd, Leonardo De Maria, Juan Carlos Mobarec, Lawrence Shapiro, Barry Honig, Andrew Buchanan, Richard A Friesner, Lingle Wang
Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculations. bioRxiv : the preprint server for biology (2024)
Jared M Sampson, Daniel A Cannon, Jianxin Duan, Jordan C K Epstein, Alina P Sergeeva, Phinikoula S Katsamba, Seetha M Mannepalli, Fabiana A Bahna, Hélène Adihou, Stéphanie M Guéret, Ranganath Gopalakrishnan, Stefan Geschwindner, D Gareth Rees, Anna Sigurdardottir, Trevor Wilkinson, Roger B Dodd, Leonardo De Maria, Juan Carlos Mobarec, Lawrence Shapiro, Barry Honig, Andrew Buchanan, Richard A Friesner, Lingle Wang
Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculations. bioRxiv : the preprint server for biology (2024)
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, Lisa Wissler, Richard J Lewis, Emma Danelius, Andreas Luttens, Pierre Matricon, Jens Carlsson, Stijn Lenders, Beate König, Anna Friedel, Peter Sjö, Stefan Schiesser, Jan Kihlberg
Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction". Journal of medicinal chemistry (2023)
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, Lisa Wissler, Richard J Lewis, Emma Danelius, Andreas Luttens, Pierre Matricon, Jens Carlsson, Stijn Lenders, Beate König, Anna Friedel, Peter Sjö, Stefan Schiesser, Jan Kihlberg
Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction". Journal of medicinal chemistry 66 (3) (2023)
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, Lisa Wissler, Richard J Lewis, Emma Danelius, Andreas Luttens, Pierre Matricon, Jens Carlsson, Stijn Lenders, Beate König, Anna Friedel, Peter Sjö, Stefan Schiesser, Jan Kihlberg
Correction to "Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction". Journal of medicinal chemistry 66 (3) (2023)
Fabio Begnini, Stefan Geschwindner, Patrik Johansson, Lisa Wissler, Richard J Lewis, Emma Danelius, Andreas Luttens, Pierre Matricon, Jens Carlsson, Stijn Lenders, Beate König, Anna Friedel, Peter Sjö, Stefan Schiesser, Jan Kihlberg
Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1-Nrf2 Protein-Protein Interaction. Journal of medicinal chemistry 65 (4) (2022)
Andrew X Zhang, Katelyn Cassidy, Stefan Geschwindner, Kevin Moreau, Fiona Pachl, Andrea M Zuhl
The Vital Role of Proteomics in Characterizing Novel Protein Degraders. SLAS discovery : advancing life sciences R & D 26 (4) (2021)
Aspen Rene Gutgsell, Anders Gunnarsson, Patrik Forssén, Euan Gordon, Torgny Fornstedt, Stefan Geschwindner
Biosensor-Enabled Deconvolution of the Avidity-Induced Affinity Enhancement for the SARS-CoV-2 Spike Protein and ACE2 Interaction. Analytical chemistry 94 (2) (2021)
Anders Gunnarsson, Christopher J Stubbs, Philip B Rawlins, Eleanor Taylor-Newman, Wei-Chao Lee, Stefan Geschwindner, Vesa Pekka Hytönen, Geoffrey Holdgate, Rupam Jha, Göran Dahl
Regenerable Biosensors for Small-Molecule Kinetic Characterization Using SPR. SLAS discovery : advancing life sciences R & D 26 (5) (2020)
Fabio Begnini, Vasanthanathan Poongavanam, Björn Over, Marie Castaldo, Stefan Geschwindner, Patrik Johansson, Mohit Tyagi, Christian Tyrchan, Lisa Wissler, Peter Sjö, Stefan Schiesser, Jan Kihlberg
Mining Natural Products for Macrocycles to Drug Difficult Targets. Journal of medicinal chemistry 64 (2) (2020)
Engi Hassaan, Per-Olof Eriksson, Stefan Geschwindner, Andreas Heine, Gerhard Klebe
Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. ChemMedChem 15 (3) (2020)
Stefan Geschwindner, Johan Ulander
The current impact of water thermodynamics for small-molecule drug discovery. Expert opinion on drug discovery 14 (12) (2019)
Namik Akkilic, Mathias Liljeblad, Stefan Blaho, Mikko Hölttä, Fredrik Höök, Stefan Geschwindner
Avidity-Based Affinity Enhancement Using Nanoliposome-Amplified SPR Sensing Enables Low Picomolar Detection of Biologically Active Neuregulin 1. ACS sensors 4 (12) (2019)
Dean G Brown, Giles A Brown, Paolo Centrella, Kaan Certel, Robert M Cooke, John W Cuozzo, Niek Dekker, Christoph E Dumelin, Andrew Ferguson, Cédric Fiez-Vandal, Stefan Geschwindner, Marie-Aude Guié, Sevan Habeshian, Anthony D Keefe, Oliver Schlenker, Eric A Sigel, Arjan Snijder, Holly T Soutter, Linda Sundström, Dawn M Troast, Giselle Wiggin, Jing Zhang, Ying Zhang, Matthew A Clark
Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target. SLAS discovery : advancing life sciences R & D 23 (5) (2018)
Lena Ripa, Karl Edman, Matthew Dearman, Goran Edenro, Ramon Hendrickx, Victoria Ullah, Hui-Fang Chang, Matti Lepistö, Dave Chapman, Stefan Geschwindner, Lisa Wissler, Petter Svanberg, Karolina Lawitz, Jesper Malmberg, Antonios Nikitidis, Roine I Olsson, James Bird, Antonio Llinas, Tove Hegelund-Myrbäck, Markus Berger, Philip Thorne, Richard Harrison, Christian Köhler, Tomas Drmota
Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile. Journal of medicinal chemistry 61 (5) (2018)
Tim Kaminski, Stefan Geschwindner
Perspectives on optical biosensor utility in small-molecule screening. Expert opinion on drug discovery 12 (11) (2017)
Molly Chilton, Ben Clennell, Fredrik Edfeldt, Stefan Geschwindner
Hot-Spotting with Thermal Scanning: A Ligand- and Structure-Independent Assessment of Target Ligandability. Journal of medicinal chemistry 60 (12) (2017)
Michael R Witten, Lisa Wissler, Melanie Snow, Stefan Geschwindner, Jon A Read, Nicholas J Brandon, Angus C Nairn, Paul J Lombroso, Helena Käck, Jonathan A Ellman
X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors. Journal of medicinal chemistry 60 (22) (2017)
Tim Kaminski, Anders Gunnarsson, Stefan Geschwindner
Harnessing the Versatility of Optical Biosensors for Target-Based Small-Molecule Drug Discovery. ACS sensors 2 (1) (2016)