Jia-Heng Tan

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 38

Top Topics

Fluorescent Probe

Top Venues

Journal of medicinal chemistry

Analytical chemistry

Angewandte Chemie (International ed. in English)

This page only lists publications with an associated author ORCID identifier.

Publications

Zhi Jiang, Yu-Tao Hu, Shi-Yao Guo, Yi-Xian Li, Dan-Dan Zhao, Li-Yuan Wei, Yu-Wei Lin, Shu-Min Xu, Shi-Liang Huang, Qing-Jiang Li, Jia-Heng Tan, Yong Rao, Shuo-Bin Chen, Shuo-Bin Chen
Development of Novel N -Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group. Journal of medicinal chemistry 67 (14) (2024)
Zhi Jiang, Yu-Tao Hu, Shi-Yao Guo, Yi-Xian Li, Dan-Dan Zhao, Li-Yuan Wei, Yu-Wei Lin, Shu-Min Xu, Shi-Liang Huang, Qing-Jiang Li, Jia-Heng Tan, Yong Rao, Shuo-Bin Chen, Shuo-Bin Chen
Development of Novel N -Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group. Journal of medicinal chemistry 67 (14) (2024)
Zhi Jiang, Yu-Tao Hu, Shi-Yao Guo, Yi-Xian Li, Dan-Dan Zhao, Li-Yuan Wei, Yu-Wei Lin, Shu-Min Xu, Shi-Liang Huang, Qing-Jiang Li, Jia-Heng Tan, Yong Rao, Shuo-Bin Chen, Shuo-Bin Chen
Development of Novel N -Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group. Journal of medicinal chemistry (2024)
Mao-Lin Li, Le-Tian Dai, Zhuo-Yu Gao, Jia-Tong Yan, Shu-Min Xu, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen, Xiu-Cai Chen
Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5'-UTR RNA G-Quadruplexes. Journal of medicinal chemistry (2024)
Zhi Jiang, Yu-Tao Hu, Shi-Yao Guo, Yi-Xian Li, Dan-Dan Zhao, Li-Yuan Wei, Yu-Wei Lin, Shu-Min Xu, Shi-Liang Huang, Qing-Jiang Li, Jia-Heng Tan, Yong Rao, Shuo-Bin Chen, Shuo-Bin Chen
Development of Novel N -Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group. Journal of medicinal chemistry 67 (14) (2024)
Mao-Lin Li, Le-Tian Dai, Zhuo-Yu Gao, Jia-Tong Yan, Shu-Min Xu, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen, Xiu-Cai Chen
Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5'-UTR RNA G-Quadruplexes. Journal of medicinal chemistry 67 (3) (2024)
Mao-Lin Li, Le-Tian Dai, Zhuo-Yu Gao, Jia-Tong Yan, Shu-Min Xu, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen, Xiu-Cai Chen
Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5'-UTR RNA G-Quadruplexes. Journal of medicinal chemistry 67 (3) (2024)
Danyang Ji, Jia-Hao Yuan, Shuo-Bin Chen, Jia-Heng Tan, Chun Kit Kwok
Selective targeting of parallel G-quadruplex structure using L-RNA aptamer. Nucleic acids research (2023)
Jia-En Wang, Ying-Chen Zhou, Bi-Han Wu, Xiu-Cai Chen, Junqiu Zhai, Jia-Heng Tan, Zhi-Shu Huang, Shuo-Bin Chen
A rapid and highly sensitive immunosorbent assay to monitor helicases unwinding diverse nucleic acid structures. The Analyst 148 (10) (2023)
Xiu-Cai Chen, Gui-Xue Tang, Jing Dai, Le-Tian Dai, Tian-Ying Wu, Wen-Wei Li, Tian-Miao Ou, Shuo-Bin Chen, Jia-Heng Tan, Shuo-Bin Chen
Discovery of Clinically Used Octenidine as NRAS Repressor That Effectively Inhibits NRAS -Mutant Melanoma. Journal of medicinal chemistry (2023)
Tian-Ying Wu, Xiu-Cai Chen, Gui-Xue Tang, Wen Shao, Zhang-Chi Li, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan
Development and Characterization of Benzoselenazole Derivatives as Potent and Selective c-MYC Transcription Inhibitors. Journal of medicinal chemistry (2023)
Jian Wang, Jia-Tong Yan, Shu-Tang Zeng, Wen Shao, Gui-Xue Tang, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan, Xiu-Cai Chen
Revealing Mitochondrion-Lysosome Dynamic Interactions and pH Variations in Live Cells with a pH-Sensitive Fluorescent Probe. Analytical chemistry (2023)
Yao-Hao Xu, Yu-Tao Hu, Shu-Min Xu, Bing-Bing Song, Hao Yuan, Dan-Dan Zhao, Shi-Yao Guo, Zhi Jiang, Li-Yuan Wei, Yong Rao, Jia-Heng Tan, Shi-Liang Huang, Qing-Jiang Li, Shuo-Bin Chen, Shuo-Bin Chen
Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer. Journal of medicinal chemistry (2023)
Jia-En Wang, Ying-Chen Zhou, Bi-Han Wu, Xiu-Cai Chen, Junqiu Zhai, Jia-Heng Tan, Zhi-Shu Huang, Shuo-Bin Chen
A rapid and highly sensitive immunosorbent assay to monitor helicases unwinding diverse nucleic acid structures. The Analyst 148 (10) (2023)
Shu-Tang Zeng, Wen Shao, Ze-Yi Yu, Lan Fang, Gui-Xue Tang, Yu-Ying Fang, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan, Xiu-Cai Chen
Construction of a TICT-AIE-Integrated Unimolecular Platform for Imaging Lipid Droplet-Mitochondrion Interactions in Live Cells and In Vivo . ACS sensors 8 (1) (2022)
Tamaki Endoh, Jia-Heng Tan, Shuo-Bin Chen, Naoki Sugimoto
Cladogenetic Orthogonal Light-Up Aptamers for Simultaneous Detection of Multiple Small Molecules in Cells. Analytical chemistry 95 (2) (2022)
Shu-Tang Zeng, Wen Shao, Ze-Yi Yu, Lan Fang, Gui-Xue Tang, Yu-Ying Fang, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan, Xiu-Cai Chen
Construction of a TICT-AIE-Integrated Unimolecular Platform for Imaging Lipid Droplet-Mitochondrion Interactions in Live Cells and In Vivo . ACS sensors 8 (1) (2022)
Tamaki Endoh, Jia-Heng Tan, Shuo-Bin Chen, Naoki Sugimoto
Cladogenetic Orthogonal Light-Up Aptamers for Simultaneous Detection of Multiple Small Molecules in Cells. Analytical chemistry 95 (2) (2022)
Shu-Tang Zeng, Wen Shao, Ze-Yi Yu, Lan Fang, Gui-Xue Tang, Yu-Ying Fang, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan, Xiu-Cai Chen
Construction of a TICT-AIE-Integrated Unimolecular Platform for Imaging Lipid Droplet-Mitochondrion Interactions in Live Cells and In Vivo . ACS sensors (2022)
Mao-Lin Li, Jing-Mei Yuan, Hao Yuan, Bi-Han Wu, Shi-Liang Huang, Qing-Jiang Li, Tian-Miao Ou, Hong-Gen Wang, Jia-Heng Tan, Ding Li, Shuo-Bin Chen, Shuo-Bin Chen
Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex. Journal of medicinal chemistry 65 (19) (2022)
Tamaki Endoh, Jia-Heng Tan, Shuo-Bin Chen, Naoki Sugimoto
Cladogenetic Orthogonal Light-Up Aptamers for Simultaneous Detection of Multiple Small Molecules in Cells. Analytical chemistry 95 (2) (2022)
Kaixin Lyu, Shuo-Bin Chen, Eugene Yui-Ching Chow, Haizhou Zhao, Jia-Hao Yuan, Meng Cai, Jiahai Shi, Ting-Fung Chan, Jia-Heng Tan, Chun Kit Kwok
An RNA G-Quadruplex Structure within the ADAR 5'UTR Interacts with DHX36 Helicase to Regulate Translation. Angewandte Chemie (International ed. in English) (2022)
Tamaki Endoh, Jia-Heng Tan, Shuo-Bin Chen, Naoki Sugimoto
Cladogenetic Orthogonal Light-Up Aptamers for Simultaneous Detection of Multiple Small Molecules in Cells. Analytical chemistry (2022)
Jia-Hao Yuan, Jia-Li Tu, Guo-Cai Liu, Xiu-Cai Chen, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan
Visualization of ligand-induced c-MYC duplex-quadruplex transition and direct exploration of the altered c-MYC DNA-protein interactions in cells. Nucleic acids research 50 (8) (2022)
Shu-Tang Zeng, Wen Shao, Ze-Yi Yu, Lan Fang, Gui-Xue Tang, Yu-Ying Fang, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan, Xiu-Cai Chen
Construction of a TICT-AIE-Integrated Unimolecular Platform for Imaging Lipid Droplet-Mitochondrion Interactions in Live Cells and In Vivo . ACS sensors 8 (1) (2022)
Huai Chen, Jiang Xu, Yaping Wang, Da Wang, Raquel Ferrer-Espada, Yutong Wang, Jingjian Zhou, Adrián Pedrazo-Tardajos, Mei Yang, Jia-Heng Tan, Xiaoyu Yang, Lei Zhang, Ilya Sychugov, Shoudeng Chen, Dries van Thourhout, Johan Paulsson, Zhenyu Yang
Color-Switchable Nanosilicon Fluorescent Probes. ACS nano 16 (9) (2022)
Xin-Chen Jiang, Fang-Hai Tu, Li-Yuan Wei, Bo-Zheng Wang, Hao Yuan, Jing-Mei Yuan, Yong Rao, Shi-Liang Huang, Qing-Jiang Li, Tian-Miao Ou, Hong-Gen Wang, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer. Journal of medicinal chemistry 65 (18) (2022)
Wen Shao, Shu-Tang Zeng, Ze-Yi Yu, Gui-Xue Tang, Shuo-Bin Chen, Shuo-Bin Chen, Xiu-Cai Chen, Jia-Heng Tan
Tracking Stress Granule Dynamics in Live Cells and In Vivo with a Small Molecule. Analytical chemistry (2021)
Xiu-Cai Chen, Gui-Xue Tang, Wen-Hua Luo, Wen Shao, Jing Dai, Shu-Tang Zeng, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan
Monitoring and Modulating mtDNA G-Quadruplex Dynamics Reveal Its Close Relationship to Cell Glycolysis. Journal of the American Chemical Society (2021)
Chen-Xi Wang, Zi-Lin Zhang, Qi-Kun Yin, Jia-Li Tu, Jia-En Wang, Yao-Hao Xu, Yong Rao, Tian-Miao Ou, Shi-Liang Huang, Ding Li, Hong-Gen Wang, Qing-Jiang Li, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors. Journal of medicinal chemistry 63 (17) (2020)
Ming-Hao Hu, Jingwei Zhou, Wen-Hua Luo, Shuo-Bin Chen, Shuo-Bin Chen, Ruibo Wu, Jia-Heng Tan
Development of a Smart Fluorescent Sensor That Specifically Recognizes the c-MYC G-Quadruplex. Analytical chemistry 91 (3) (2019)
Qi-Kun Yin, Chen-Xi Wang, Yu-Qing Wang, Qian-Liang Guo, Zi-Lin Zhang, Tian-Miao Ou, Shi-Liang Huang, Ding Li, Hong-Gen Wang, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Discovery of Isaindigotone Derivatives as Novel Bloom's Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair. Journal of medicinal chemistry 62 (6) (2019)
Kaixin Lyu, Shuo-Bin Chen, Chun-Yin Chan, Jia-Heng Tan, Chun Kit Kwok
Structural analysis and cellular visualization of APP RNA G-quadruplex. Chemical science 10 (48) (2019)
Ming-Hao Hu, Yu-Qing Wang, Ze-Yi Yu, Lu-Ni Hu, Tian-Miao Ou, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan
Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex. Journal of medicinal chemistry 61 (6) (2018)
Tong Che, Shuo-Bin Chen, Jia-Li Tu, Bo Wang, Yu-Qing Wang, Yan Zhang, Jing Wang, Zeng-Qing Wang, Ze-Peng Zhang, Tian-Miao Ou, Yong Zhao, Jia-Heng Tan, Shuo-Bin Chen
Discovery of Novel Schizocommunin Derivatives as Telomeric G-Quadruplex Ligands That Trigger Telomere Dysfunction and the Deoxyribonucleic Acid (DNA) Damage Response. Journal of medicinal chemistry 61 (8) (2018)
Wang Peng, Zhi-Yin Sun, Qi Zhang, Sui-Qi Cheng, Shi-Ke Wang, Xiao-Na Wang, Guo-Tao Kuang, Xiao-Xuan Su, Jia-Heng Tan, Shuo-Bin Chen, Tian-Miao Ou
Design, Synthesis, and Evaluation of Novel p-(Methylthio)styryl Substituted Quindoline Derivatives as Neuroblastoma RAS (NRAS) Repressors via Specific Stabilizing the RNA G-Quadruplex. Journal of medicinal chemistry 61 (15) (2018)
Xiu-Cai Chen, Shuo-Bin Chen, Jing Dai, Jia-Hao Yuan, Tian-Miao Ou, Zhi-Shu Huang, Jia-Heng Tan
Tracking the Dynamic Folding and Unfolding of RNA G-Quadruplexes in Live Cells. Angewandte Chemie (International ed. in English) 57 (17) (2018)
Zhou-Li Huang, Jing Dai, Wen-Hua Luo, Xiang-Gui Wang, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Identification of G-Quadruplex-Binding Protein from the Exploration of RGG Motif/G-Quadruplex Interactions. Journal of the American Chemical Society 140 (51) (2018)