Shuo-Bin Chen (Zhi-Shu Huang)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 51

Top Topics

Binding Protein

Fluorescent Probe

Endoplasmic Reticulum

Top Venues

Journal of medicinal chemistry

Molecules (Basel, Switzerland)

Organic letters

This page only lists publications with an associated author ORCID identifier.

Publications

Zhi Jiang, Yu-Tao Hu, Shi-Yao Guo, Yi-Xian Li, Dan-Dan Zhao, Li-Yuan Wei, Yu-Wei Lin, Shu-Min Xu, Shi-Liang Huang, Qing-Jiang Li, Jia-Heng Tan, Yong Rao, Shuo-Bin Chen, Shuo-Bin Chen
Development of Novel N -Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group. Journal of medicinal chemistry 67 (14) (2024)
Zhi Jiang, Yu-Tao Hu, Shi-Yao Guo, Yi-Xian Li, Dan-Dan Zhao, Li-Yuan Wei, Yu-Wei Lin, Shu-Min Xu, Shi-Liang Huang, Qing-Jiang Li, Jia-Heng Tan, Yong Rao, Shuo-Bin Chen, Shuo-Bin Chen
Development of Novel N -Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group. Journal of medicinal chemistry 67 (14) (2024)
Zhi Jiang, Yu-Tao Hu, Shi-Yao Guo, Yi-Xian Li, Dan-Dan Zhao, Li-Yuan Wei, Yu-Wei Lin, Shu-Min Xu, Shi-Liang Huang, Qing-Jiang Li, Jia-Heng Tan, Yong Rao, Shuo-Bin Chen, Shuo-Bin Chen
Development of Novel N -Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group. Journal of medicinal chemistry (2024)
Mao-Lin Li, Le-Tian Dai, Zhuo-Yu Gao, Jia-Tong Yan, Shu-Min Xu, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen, Xiu-Cai Chen
Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5'-UTR RNA G-Quadruplexes. Journal of medicinal chemistry (2024)
Zhi Jiang, Yu-Tao Hu, Shi-Yao Guo, Yi-Xian Li, Dan-Dan Zhao, Li-Yuan Wei, Yu-Wei Lin, Shu-Min Xu, Shi-Liang Huang, Qing-Jiang Li, Jia-Heng Tan, Yong Rao, Shuo-Bin Chen, Shuo-Bin Chen
Development of Novel N -Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group. Journal of medicinal chemistry 67 (14) (2024)
Mao-Lin Li, Le-Tian Dai, Zhuo-Yu Gao, Jia-Tong Yan, Shu-Min Xu, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen, Xiu-Cai Chen
Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5'-UTR RNA G-Quadruplexes. Journal of medicinal chemistry 67 (3) (2024)
Mao-Lin Li, Le-Tian Dai, Zhuo-Yu Gao, Jia-Tong Yan, Shu-Min Xu, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen, Xiu-Cai Chen
Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5'-UTR RNA G-Quadruplexes. Journal of medicinal chemistry 67 (3) (2024)
Bo-Zheng Wang, Ying-Chen Zhou, Yu-Wei Lin, Xiu-Cai Chen, Ze-Yi Yu, Yao-Hao Xu, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Fluorescent Quinolinium Derivative as Novel Mitochondria Probe and Function Modulator by Targeting Mitochondrial RNA. Molecules (Basel, Switzerland) 28 (6) (2023)
Jie-Bin Ou, Wei-Hao Huang, Xing-Zi Liu, Guo-Yao Dai, Lu Wang, Shuo-Bin Chen, Shi-Liang Huang
MSN8C: A Promising Candidate for Antitumor Applications as a Novel Catalytic Inhibitor of Topoisomerase II. Molecules (Basel, Switzerland) 28 (14) (2023)
Bo-Zheng Wang, Ying-Chen Zhou, Yu-Wei Lin, Xiu-Cai Chen, Ze-Yi Yu, Yao-Hao Xu, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Fluorescent Quinolinium Derivative as Novel Mitochondria Probe and Function Modulator by Targeting Mitochondrial RNA. Molecules (Basel, Switzerland) 28 (6) (2023)
Xiu-Cai Chen, Gui-Xue Tang, Jing Dai, Le-Tian Dai, Tian-Ying Wu, Wen-Wei Li, Tian-Miao Ou, Shuo-Bin Chen, Jia-Heng Tan, Shuo-Bin Chen
Discovery of Clinically Used Octenidine as NRAS Repressor That Effectively Inhibits NRAS -Mutant Melanoma. Journal of medicinal chemistry (2023)
Bo-Zheng Wang, Ying-Chen Zhou, Yu-Wei Lin, Xiu-Cai Chen, Ze-Yi Yu, Yao-Hao Xu, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Fluorescent Quinolinium Derivative as Novel Mitochondria Probe and Function Modulator by Targeting Mitochondrial RNA. Molecules (Basel, Switzerland) 28 (6) (2023)
Tian-Ying Wu, Xiu-Cai Chen, Gui-Xue Tang, Wen Shao, Zhang-Chi Li, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan
Development and Characterization of Benzoselenazole Derivatives as Potent and Selective c-MYC Transcription Inhibitors. Journal of medicinal chemistry (2023)
Shu-Qi Wu, Xinying Zhu, Tao Yuan, Fang-Yu Yuan, Shiyou Zhou, Dong Huang, Ying Wang, Gui-Hua Tang, Shuo-Bin Chen, Xin Chen, Sheng Yin
Discovery of Ingenane Diterpenoids from Euphorbia hylonoma as Antiadipogenic Agents. Journal of natural products (2023)
Jian Wang, Jia-Tong Yan, Shu-Tang Zeng, Wen Shao, Gui-Xue Tang, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan, Xiu-Cai Chen
Revealing Mitochondrion-Lysosome Dynamic Interactions and pH Variations in Live Cells with a pH-Sensitive Fluorescent Probe. Analytical chemistry (2023)
Yao-Hao Xu, Yu-Tao Hu, Shu-Min Xu, Bing-Bing Song, Hao Yuan, Dan-Dan Zhao, Shi-Yao Guo, Zhi Jiang, Li-Yuan Wei, Yong Rao, Jia-Heng Tan, Shi-Liang Huang, Qing-Jiang Li, Shuo-Bin Chen, Shuo-Bin Chen
Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer. Journal of medicinal chemistry (2023)
Xue-Long Yan, Yue-Hua Pan, Run-Zhu Fan, Qin-Qin Song, Shen Li, Jia-Luo Huang, Wei Li, Dong Huang, Fang-Yu Yuan, Gui-Hua Tang, Yong Rao, Shuo-Bin Chen, Sheng Yin
Discovery of the First Raptor (Regulatory-Associated Protein of mTOR) Inhibitor as a New Type of Antiadipogenic Agent. Journal of medicinal chemistry (2023)
Lan Fang, Wen Shao, Shu-Tang Zeng, Gui-Xue Tang, Jia-Tong Yan, Shuo-Bin Chen, Zhi-Shu Huang, Jia-Heng Tan, Xiu-Cai Chen
Development of a Highly Selective and Sensitive Fluorescent Probe for Imaging RNA Dynamics in Live Cells. Molecules (Basel, Switzerland) 27 (20) (2022)
Shu-Qi Wu, Run-Zhu Fan, Fang-Yu Yuan, Wei Li, Dong Huang, Shen Li, Gui-Hua Tang, Shuo-Bin Chen, Sheng Yin
Euphylonoids A and B, Two Highly Modified Jatrophane Diterpenoids with Potent Lipid-Lowering Activity from Euphorbia hylonoma . Organic letters (2022)
Shu-Tang Zeng, Wen Shao, Ze-Yi Yu, Lan Fang, Gui-Xue Tang, Yu-Ying Fang, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan, Xiu-Cai Chen
Construction of a TICT-AIE-Integrated Unimolecular Platform for Imaging Lipid Droplet-Mitochondrion Interactions in Live Cells and In Vivo . ACS sensors 8 (1) (2022)
Shu-Tang Zeng, Wen Shao, Ze-Yi Yu, Lan Fang, Gui-Xue Tang, Yu-Ying Fang, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan, Xiu-Cai Chen
Construction of a TICT-AIE-Integrated Unimolecular Platform for Imaging Lipid Droplet-Mitochondrion Interactions in Live Cells and In Vivo . ACS sensors 8 (1) (2022)
Shu-Tang Zeng, Wen Shao, Ze-Yi Yu, Lan Fang, Gui-Xue Tang, Yu-Ying Fang, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan, Xiu-Cai Chen
Construction of a TICT-AIE-Integrated Unimolecular Platform for Imaging Lipid Droplet-Mitochondrion Interactions in Live Cells and In Vivo . ACS sensors (2022)
Mao-Lin Li, Jing-Mei Yuan, Hao Yuan, Bi-Han Wu, Shi-Liang Huang, Qing-Jiang Li, Tian-Miao Ou, Hong-Gen Wang, Jia-Heng Tan, Ding Li, Shuo-Bin Chen, Shuo-Bin Chen
Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex. Journal of medicinal chemistry 65 (19) (2022)
Shu-Tang Zeng, Wen Shao, Ze-Yi Yu, Lan Fang, Gui-Xue Tang, Yu-Ying Fang, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan, Xiu-Cai Chen
Construction of a TICT-AIE-Integrated Unimolecular Platform for Imaging Lipid Droplet-Mitochondrion Interactions in Live Cells and In Vivo . ACS sensors 8 (1) (2022)
Long-Ling Huang, Peng-Peng Lin, Yu-Xin Li, Si-Xin Feng, Fang-Hai Tu, Shuang Yang, Gui-Yang Zhao, Shuo-Bin Chen, Hong-Gen Wang, Qing-Jiang Li
Oxidative Fluoroarylation of Benzylidenecyclopropanes with HF·Py and Aryl Iodides via Iodonio-[3,3]-Rearrangement. Organic letters 24 (18) (2022)
Xin-Chen Jiang, Fang-Hai Tu, Li-Yuan Wei, Bo-Zheng Wang, Hao Yuan, Jing-Mei Yuan, Yong Rao, Shi-Liang Huang, Qing-Jiang Li, Tian-Miao Ou, Hong-Gen Wang, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer. Journal of medicinal chemistry 65 (18) (2022)
Shuangshuang Kang, Jiaojiao Cao, Meiling Zhang, Xiaoya Li, Qian-Liang Guo, Huang Zeng, Zuzhuang Wei, Xue Gong, Jing Wang, Bobo Liu, Bing Shu, Xiaoli Xu, Shuo-Bin Chen, Ding Li
Transcriptional regulation of telomeric repeat-containing RNA by acridine derivatives. RNA biology 18 (12) (2021)
Wen Shao, Shu-Tang Zeng, Ze-Yi Yu, Gui-Xue Tang, Shuo-Bin Chen, Shuo-Bin Chen, Xiu-Cai Chen, Jia-Heng Tan
Tracking Stress Granule Dynamics in Live Cells and In Vivo with a Small Molecule. Analytical chemistry (2021)
Yong Rao, Chan Li, Yu-Tao Hu, Yao-Hao Xu, Bing-Bing Song, Shi-Yao Guo, Zhi Jiang, Dan-Dan Zhao, Shuo-Bin Chen, Jia-Heng Tan, Shi-Liang Huang, Qing-Jiang Li, Xiao-Jun Wang, Ying-Jun Zhang, Ji-Ming Ye, Shuo-Bin Chen
A novel HSF1 activator ameliorates nonalcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation. British journal of pharmacology (2021)
Yao Liu, Ji-Lin Li, Xu-Ge Liu, Jia-Qiang Wu, Shuo-Bin Chen, Qing-Jiang Li, Hong-Gen Wang
Radical Borylative Cyclization of Isocyanoarenes with N-Heterocyclic Carbene Borane: Synthesis of Borylated Aza-arenes. Organic letters 23 (5) (2021)
Peng-Peng Lin, Long-Ling Huang, Si-Xin Feng, Shuang Yang, Hong-Gen Wang, Shuo-Bin Chen, Qing-Jiang Li
gem-Difluorination of Methylenecyclopropanes (MCPs) Featuring a Wagner-Meerwein Rearrangement: Synthesis of 2-Arylsubstituted gem-Difluorocyclobutanes. Organic letters 23 (8) (2021)
Si-Xin Feng, Shuang Yang, Fang-Hai Tu, Peng-Peng Lin, Long-Ling Huang, Hong-Gen Wang, Shuo-Bin Chen, Qing-Jiang Li
Iodine(III)-Mediated Fluorination/Semipinacol Rearrangement Cascade of 2-Alkylidenecyclobutanol Derivatives: Access to β-Monofluorinated Cyclopropanecarbaldehydes. The Journal of organic chemistry 86 (9) (2021)
Xiu-Cai Chen, Gui-Xue Tang, Wen-Hua Luo, Wen Shao, Jing Dai, Shu-Tang Zeng, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan
Monitoring and Modulating mtDNA G-Quadruplex Dynamics Reveal Its Close Relationship to Cell Glycolysis. Journal of the American Chemical Society (2021)
Chen-Xi Wang, Zi-Lin Zhang, Qi-Kun Yin, Jia-Li Tu, Jia-En Wang, Yao-Hao Xu, Yong Rao, Tian-Miao Ou, Shi-Liang Huang, Ding Li, Hong-Gen Wang, Qing-Jiang Li, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors. Journal of medicinal chemistry 63 (17) (2020)
Guotao Kuang, Meiling Zhang, Shuangshuang Kang, Dexuan Hu, Xiaoya Li, Zuzhuang Wei, Xue Gong, Lin-Kun An, Shuo-Bin Chen, Bing Shu, Ding Li
Syntheses and Evaluation of New Bisacridine Derivatives for Dual Binding of G-Quadruplex and i-Motif in Regulating Oncogene c-myc Expression. Journal of medicinal chemistry 63 (17) (2020)
Yong Rao, Yu-Ting Lu, Chan Li, Qin-Qin Song, Yao-Hao Xu, Zhao Xu, Yu-Tao Hu, Hong Yu, Lin Gao, Lian-Quan Gu, Ji-Ming Ye, Shuo-Bin Chen
Bouchardatine analogue alleviates non-alcoholic hepatic fatty liver disease/non-alcoholic steatohepatitis in high-fat fed mice by inhibiting ATP synthase activity. British journal of pharmacology 176 (16) (2019)
Ming-Hao Hu, Jingwei Zhou, Wen-Hua Luo, Shuo-Bin Chen, Shuo-Bin Chen, Ruibo Wu, Jia-Heng Tan
Development of a Smart Fluorescent Sensor That Specifically Recognizes the c-MYC G-Quadruplex. Analytical chemistry 91 (3) (2019)
Qin-Qin Song, Yong Rao, Gui-Hua Tang, Zhang-Hua Sun, Jun-Sheng Zhang, Shuo-Bin Chen, Sheng Yin
Tigliane Diterpenoids as a New Type of Antiadipogenic Agents Inhibit GRα-Dexras1 Axis in Adipocytes. Journal of medicinal chemistry 62 (4) (2019)
Qi-Kun Yin, Chen-Xi Wang, Yu-Qing Wang, Qian-Liang Guo, Zi-Lin Zhang, Tian-Miao Ou, Shi-Liang Huang, Ding Li, Hong-Gen Wang, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Discovery of Isaindigotone Derivatives as Novel Bloom's Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair. Journal of medicinal chemistry 62 (6) (2019)
Wei Li, Ya-Qi Tang, Shi-Xin Chen, Gui-Hua Tang, Li-She Gan, Chan Li, Yong Rao, Shuo-Bin Chen, Sheng Yin
Euphorhelipanes A and B, Triglyceride-Lowering Euphorbia Diterpenoids with a Bicyclo[4.3.0]nonane Core from Euphorbia helioscopia. Journal of natural products 82 (2) (2019)
Ming-Hao Hu, Yu-Qing Wang, Ze-Yi Yu, Lu-Ni Hu, Tian-Miao Ou, Shuo-Bin Chen, Shuo-Bin Chen, Jia-Heng Tan
Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex. Journal of medicinal chemistry 61 (6) (2018)
Tong Che, Yu-Qing Wang, Zhou-Li Huang, Jia-Heng Tan, Zhi-Shu Huang, Shuo-Bin Chen
Natural Alkaloids and Heterocycles as G-Quadruplex Ligands and Potential Anticancer Agents. Molecules (Basel, Switzerland) 23 (2) (2018)
Tong Che, Shuo-Bin Chen, Jia-Li Tu, Bo Wang, Yu-Qing Wang, Yan Zhang, Jing Wang, Zeng-Qing Wang, Ze-Peng Zhang, Tian-Miao Ou, Yong Zhao, Jia-Heng Tan, Shuo-Bin Chen
Discovery of Novel Schizocommunin Derivatives as Telomeric G-Quadruplex Ligands That Trigger Telomere Dysfunction and the Deoxyribonucleic Acid (DNA) Damage Response. Journal of medicinal chemistry 61 (8) (2018)
Wang Peng, Zhi-Yin Sun, Qi Zhang, Sui-Qi Cheng, Shi-Ke Wang, Xiao-Na Wang, Guo-Tao Kuang, Xiao-Xuan Su, Jia-Heng Tan, Shuo-Bin Chen, Tian-Miao Ou
Design, Synthesis, and Evaluation of Novel p-(Methylthio)styryl Substituted Quindoline Derivatives as Neuroblastoma RAS (NRAS) Repressors via Specific Stabilizing the RNA G-Quadruplex. Journal of medicinal chemistry 61 (15) (2018)
Zhou-Li Huang, Jing Dai, Wen-Hua Luo, Xiang-Gui Wang, Jia-Heng Tan, Shuo-Bin Chen, Shuo-Bin Chen
Identification of G-Quadruplex-Binding Protein from the Exploration of RGG Motif/G-Quadruplex Interactions. Journal of the American Chemical Society 140 (51) (2018)
Shi-Ke Wang, Yue Wu, Xiao-Qin Wang, Guo-Tao Kuang, Qi Zhang, Shu-Ling Lin, Hui-Yun Liu, Jia-Heng Tan, Shuo-Bin Chen, Tian-Miao Ou
Discovery of Small Molecules for Repressing Cap-Independent Translation of Human Vascular Endothelial Growth Factor (hVEGF) as Novel Antitumor Agents. Journal of medicinal chemistry 60 (13) (2017)
Yong Rao, Hong Yu, Lin Gao, Yu-Ting Lu, Zhao Xu, Hong Liu, Lian-Quan Gu, Ji-Ming Ye, Shuo-Bin Chen
Natural alkaloid bouchardatine ameliorates metabolic disorders in high-fat diet-fed mice by stimulating the sirtuin 1/liver kinase B-1/AMPK axis. British journal of pharmacology 174 (15) (2017)
Yu-Qing Wang, Zhou-Li Huang, Shuo-Bin Chen, Chen-Xi Wang, Chan Shan, Qi-Kun Yin, Tian-Miao Ou, Ding Li, Lian-Quan Gu, Jia-Heng Tan, Shuo-Bin Chen
Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c-MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction. Journal of medicinal chemistry 60 (16) (2017)
Chan Shan, Jin-Wu Yan, Yu-Qing Wang, Tong Che, Zhou-Li Huang, Ai-Chun Chen, Pei-Fen Yao, Jia-Heng Tan, Ding Li, Tian-Miao Ou, Lian-Quan Gu, Shuo-Bin Chen
Design, Synthesis, and Evaluation of Isaindigotone Derivatives To Downregulate c-myc Transcription via Disrupting the Interaction of NM23-H2 with G-Quadruplex. Journal of medicinal chemistry 60 (4) (2017)
De-Ying Zeng, Guo-Tao Kuang, Shi-Ke Wang, Wang Peng, Shu-Ling Lin, Qi Zhang, Xiao-Xuan Su, Ming-Hao Hu, Hong-Gen Wang, Jia-Heng Tan, Shuo-Bin Chen, Lian-Quan Gu, Tian-Miao Ou
Discovery of Novel 11-Triazole Substituted Benzofuro[3,2-b]quinolone Derivatives as c-myc G-Quadruplex Specific Stabilizers via Click Chemistry. Journal of medicinal chemistry 60 (13) (2017)
Hui-Yun Liu, Ai-Chun Chen, Qi-Kun Yin, Zeng Li, Su-Mei Huang, Gang Du, Jin-Hui He, Li-Peng Zan, Shi-Ke Wang, Yao-Hao Xu, Jia-Heng Tan, Tian-Miao Ou, Ding Li, Lian-Quan Gu, Shuo-Bin Chen
New Disubstituted Quindoline Derivatives Inhibiting Burkitt's Lymphoma Cell Proliferation by Impeding c-MYC Transcription. Journal of medicinal chemistry 60 (13) (2017)