Jia Zhou

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 56

Top Venues

Journal of medicinal chemistry

Medicinal research reviews

Expert opinion on therapeutic targets

Viruses

University of Texas Medical Branch at Galveston

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Texas Medical Branch at Galveston

United States

Prof :: Pharmacology and Toxicology

Publications

Ryan E Murphy, Pingyuan Wang, Saghir Ali, Hudson R Smith, Daniel E Felsing, Haiying Chen, Jia Zhou, John A Allen
Discovery of 3-((4-Benzylpyridin-2-yl)amino)benzamides as Potent GPR52 G Protein-Biased Agonists. Journal of medicinal chemistry (2024)
Ryan E Murphy, Pingyuan Wang, Saghir Ali, Hudson R Smith, Daniel E Felsing, Haiying Chen, Jia Zhou, John A Allen
Discovery of 3-((4-Benzylpyridin-2-yl)amino)benzamides as Potent GPR52 G Protein-Biased Agonists. Journal of medicinal chemistry (2024)
Ryan E Murphy, Pingyuan Wang, Saghir Ali, Hudson R Smith, Daniel E Felsing, Haiying Chen, Jia Zhou, John A Allen
Discovery of 3-((4-Benzylpyridin-2-yl)amino)benzamides as Potent GPR52 G Protein-Biased Agonists. Journal of medicinal chemistry 67 (11) (2024)
Zonghui Ma, Andrew A Bolinger, Jia Zhou, Bing Tian
Bromodomain-containing protein 4 (BRD4): a key player in inflammatory bowel disease and potential to inspire epigenetic therapeutics. Expert opinion on therapeutic targets (2023)
Zonghui Ma, Andrew A Bolinger, Jia Zhou, Bing Tian
Bromodomain-containing protein 4 (BRD4): a key player in inflammatory bowel disease and potential to inspire epigenetic therapeutics. Expert opinion on therapeutic targets 27 (1) (2023)
Zonghui Ma, Andrew A Bolinger, Haiying Chen, Jia Zhou
Drug Discovery Targeting Nuclear Receptor Binding SET Domain Protein 2 (NSD2). Journal of medicinal chemistry (2023)
Zonghui Ma, Andrew A Bolinger, Jia Zhou, Bing Tian
Bromodomain-containing protein 4 (BRD4): a key player in inflammatory bowel disease and potential to inspire epigenetic therapeutics. Expert opinion on therapeutic targets 27 (1) (2023)
Jianping Chen, Erik J Garcia, Christina R Merritt, Joshua C Zamora, Andrew A Bolinger, Konrad Pazdrak, Susan J Stafford, Randy C Mifflin, Eric A Wold, Christopher T Wild, Haiying Chen, Noelle C Anastasio, Katherine A Cunningham, Jia Zhou
Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT 2C Receptor and Dual 5-HT 2C /5-HT 2A Receptor Modulators. Journal of medicinal chemistry (2023)
Jimin Xu, Yu Xue, Andrew A Bolinger, Jun Li, Mingxiang Zhou, Haiying Chen, Hongmin Li, Jia Zhou
Therapeutic potential of salicylamide derivatives for combating viral infections. Medicinal research reviews (2023)
Yu Xue, Andrew A Bolinger, Jia Zhou
Novel approaches to targeted protein degradation technologies in drug discovery. Expert opinion on drug discovery (2023)
Andrew A Bolinger, Andrew Frazier, Jun-Ho La, John A Allen, Jia Zhou
Orphan G Protein-Coupled Receptor GPR37 as an Emerging Therapeutic Target. ACS chemical neuroscience (2023)
Zonghui Ma, Andrew A Bolinger, Jia Zhou, Bing Tian
Bromodomain-containing protein 4 (BRD4): a key player in inflammatory bowel disease and potential to inspire epigenetic therapeutics. Expert opinion on therapeutic targets 27 (1) (2023)
Yuting Kuang, Na Ye, Armita Kyani, Mats Ljungman, Michelle Paulsen, Haijun Chen, Mingxiang Zhou, Christopher Wild, Haiying Chen, Jia Zhou, Nouri Neamati
Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer. Journal of medicinal chemistry 65 (8) (2022)
Subodh K Samrat, Jimin Xu, Zhong Li, Jia Zhou, Hongmin Li
Antiviral Agents against Flavivirus Protease: Prospect and Future Direction. Pathogens (Basel, Switzerland) 11 (3) (2022)
Zhi-Qing Liu, Yi Li, Haiying Chen, Hsien-Tsung Lai, Pingyuan Wang, Shwu-Yuan Wu, Eric A Wold, Paul G Leonard, Sarah Joseph, Haitao Hu, Cheng-Ming Chiang, Allan R Brasier, Bing Tian, Jia Zhou
Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site. Journal of medicinal chemistry 65 (3) (2022)
Ashwani Kumar, Galina Aglyamova, Yun Young Yim, Aaron O Bailey, Haley M Lynch, Reid T Powell, Nghi D Nguyen, Zachary Rosenthal, Wen-Ning Zhao, Yi Li, Jianping Chen, Shanghua Fan, Hubert Lee, William K Russell, Clifford Stephan, Alfred J Robison, Stephen J Haggarty, Eric J Nestler, Jia Zhou, Mischa Machius, Gabby Rudenko
Chemically targeting the redox switch in AP1 transcription factor ΔFOSB. Nucleic acids research 50 (16) (2022)
Pingyuan Wang, Daniel E Felsing, Haiying Chen, Sweta R Raval, John A Allen, Jia Zhou
Retraction of "Synthesis and Pharmacological Evaluation of Noncatechol G Protein Biased and Unbiased Dopamine D1 Receptor Agonists". ACS medicinal chemistry letters 13 (6) (2022)
Xinye Wang, Ting Qiu, Yingying Wu, Chuanyu Yang, Yi Li, Guangshi Du, Yao-Hui He, Wen Liu, Rong Liu, Chuan-Huizi Chen, Yujie Shi, Jingxuan Pan, Jia Zhou, Dewei Jiang, Ceshi Chen
Arginine methyltransferase PRMT5 methylates and stabilizes KLF5 via decreasing its phosphorylation and ubiquitination to promote basal-like breast cancer. Cell death and differentiation 28 (10) (2021)
Nolan M Dvorak, Cynthia M Tapia, Aditya K Singh, Timothy J Baumgartner, Pingyuan Wang, Haiying Chen, Paul A Wadsworth, Jia Zhou, Fernanda Laezza
Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na + Channel 1.6 Enables Isoform-Selective Modulation. International journal of molecular sciences 22 (24) (2021)
Shaojun Zhang, Vivian Changying Jiang, Guangchun Han, Dapeng Hao, Junwei Lian, Yang Liu, Rongjia Zhang, Joseph McIntosh, Ruiping Wang, Minghao Dang, Enyu Dai, Yuanxin Wang, David Santos, Maria Badillo, Angela Leeming, Zhihong Chen, Kimberly Hartig, John Bigcal, Jia Zhou, Rashmi Kanagal-Shamanna, Chi Young Ok, Hun Lee, Raphael E Steiner, Jianhua Zhang, Xingzhi Song, Ranjit Nair, Sairah Ahmed, Alma Rodriquez, Selvi Thirumurthi, Preetesh Jain, Nicolaus Wagner-Bartak, Holly A Hill, Krystle Nomie, Christopher Flowers, P Andrew Futreal, Linghua Wang, Michael L Wang
Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma. Nature communications 12 (1) (2021)
Zhong Li, Anil Mathew Tharappel, Jimin Xu, Yuekun Lang, Cathleen M Green, Jing Zhang, Qishan Lin, Sudha Chaturvedi, Jia Zhou, Marlene Belfort, Hongmin Li
Small-molecule inhibitors for the Prp8 intein as antifungal agents. Proceedings of the National Academy of Sciences of the United States of America 118 (2) (2021)
Morgan W Mann, David S Roberts, Yanlong Zhu, Yi Li, Jia Zhou, Ying Ge, Allan R Brasier
Discovery of RSV-Induced BRD4 Protein Interactions Using Native Immunoprecipitation and Parallel Accumulation-Serial Fragmentation (PASEF) Mass Spectrometry. Viruses 13 (3) (2021)
Eun-Jin Choi, Wenzhe Wu, Xiaoyan Cong, Ke Zhang, Jiaqi Luo, Sha Ye, Pingyuan Wang, Adarsh Suresh, Uneeb Mohammad Ullah, Jia Zhou, Xiaoyong Bao
Broad Impact of Exchange Protein Directly Activated by cAMP 2 (EPAC2) on Respiratory Viral Infections. Viruses 13 (6) (2021)
Aditya K Singh, Paul A Wadsworth, Cynthia M Tapia, Giuseppe Aceto, Syed R Ali, Haiying Chen, Marcello D'Ascenzo, Jia Zhou, Fernanda Laezza
Mapping of the FGF14:Nav1.6 complex interface reveals FLPK as a functionally active peptide modulating excitability. Physiological reports 8 (14) (2021)
Yi Li, Jianping Chen, Andrew A Bolinger, Haiying Chen, Zhiqing Liu, Yingzi Cong, Allan R Brasier, Irina V Pinchuk, Bing Tian, Jia Zhou
Target-Based Small Molecule Drug Discovery Towards Novel Therapeutics for Inflammatory Bowel Diseases. Inflammatory bowel diseases 27 (Suppl 2) (2021)
Zhi-Qing Liu, Pingyuan Wang, Eric A Wold, Qiaoling Song, Chenyang Zhao, Chang-Yun Wang, Jia Zhou
Small-Molecule Inhibitors Targeting the Canonical WNT Signaling Pathway for the Treatment of Cancer. Journal of medicinal chemistry 64 (8) (2021)
Jimin Xu, Judith Berastegui-Cabrera, Marta Carretero-Ledesma, Haiying Chen, Yu Xue, Eric A Wold, Jerónimo Pachón, Jia Zhou, Javier Sánchez-Céspedes
Discovery of a Small Molecule Inhibitor of Human Adenovirus Capable of Preventing Escape from the Endosome. International journal of molecular sciences 22 (4) (2021)
Mark R Hellmich, Celia Chao, Katalin Módis, Ye Ding, John R Zatarain, Ketan Thanki, Manjit Maskey, Nadiya Druzhyna, Ashley A Untereiner, Akbar Ahmad, Yu Xue, Haiying Chen, William K Russell, Jianmei Wang, Jia Zhou, Csaba Szabó
Efficacy of Novel Aminooxyacetic Acid Prodrugs in Colon Cancer Models: Towards Clinical Translation of the Cystathionine β-Synthase Inhibition Concept. Biomolecules 11 (8) (2021)
Na Ye, Wangzhi Qin, Sheng Tian, Qingfeng Xu, Eric A Wold, Jia Zhou, Xue-Chu Zhen
Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases. Journal of medicinal chemistry 63 (24) (2020)
Atif Zafar, Wei Wang, Gang Liu, Xinjie Wang, Wa Xian, Frank McKeon, Jennifer Foster, Jia Zhou, Ruiwen Zhang
Molecular targeting therapies for neuroblastoma: Progress and challenges. Medicinal research reviews 41 (2) (2020)
Pingyuan Wang, Paul A Wadsworth, Nolan M Dvorak, Aditya K Singh, Haiying Chen, Zhi-Qing Liu, Richard Zhou, Luis Marcelo F Holthauzen, Jia Zhou, Fernanda Laezza
Design, Synthesis, and Pharmacological Evaluation of Analogues Derived from the PLEV Tetrapeptide as Protein-Protein Interaction Modulators of Voltage-Gated Sodium Channel 1.6. Journal of medicinal chemistry 63 (20) (2020)
Pingyuan Wang, Urszula Luchowska-Stańska, Boy van Basten, Haiying Chen, Zhi-Qing Liu, Jolanta Wiejak, Padraic Whelan, David Morgan, Emma Lochhead, Graeme Barker, Holger Rehmann, Stephen J Yarwood, Jia Zhou
Synthesis and Biochemical Evaluation of Noncyclic Nucleotide Exchange Proteins Directly Activated by cAMP 1 (EPAC1) Regulators. Journal of medicinal chemistry 63 (10) (2020)
Jimin Xu, Judith Berastegui-Cabrera, Haiying Chen, Jerónimo Pachón, Jia Zhou, Javier Sánchez-Céspedes
Structure-Activity Relationship Studies on Diversified Salicylamide Derivatives as Potent Inhibitors of Human Adenovirus Infection. Journal of medicinal chemistry 63 (6) (2020)
Wei Wang, Xinjie Wang, Mehrdad Rajaei, Ji Youn Youn, Atif Zafar, Hemantkumar Deokar, John K Buolamwini, Jianhua Yang, Jennifer H Foster, Jia Zhou, Ruiwen Zhang
Targeting MDM2 for Neuroblastoma Therapy: In Vitro and In Vivo Anticancer Activity and Mechanism of Action. Cancers 12 (12) (2020)
Zhong Li, Jimin Xu, Yuekun Lang, Xiaoyu Fan, Lili Kuo, Lianna D'Brant, Saiyang Hu, Subodh Kumar Samrat, Nicole Trudeau, Anil M Tharappel, Natasha Rugenstein, Cheri A Koetzner, Jing Zhang, Haiying Chen, Laura D Kramer, David Butler, Qing-Yu Zhang, Jia Zhou, Hongmin Li
JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo. ACS infectious diseases 6 (10) (2020)
Hongzhao Shao, Hebatallah Mohamed, Stephen Boulton, Jinfeng Huang, Pingyuan Wang, Haiying Chen, Jia Zhou, Urszula Luchowska-Stańska, Nicholas G Jentsch, Alison L Armstrong, Jakob Magolan, Stephen Yarwood, Giuseppe Melacini
Mechanism of Action of an EPAC1-Selective Competitive Partial Agonist. Journal of medicinal chemistry 63 (9) (2020)
Gang Liu, Haiying Chen, Hua Liu, Wenbo Zhang, Jia Zhou
Emerging roles of SIRT6 in human diseases and its modulators. Medicinal research reviews 41 (2) (2020)
Jimin Xu, Yu Xue, Richard Zhou, Pei-Yong Shi, Hongmin Li, Jia Zhou
Drug repurposing approach to combating coronavirus: Potential drugs and drug targets. Medicinal research reviews 41 (3) (2020)
Nolan M Dvorak, Paul A Wadsworth, Pingyuan Wang, Haiying Chen, Jia Zhou, Fernanda Laezza
Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics. Molecules (Basel, Switzerland) 25 (15) (2020)
Wenjing Yang, Tianming Yu, Xiangsheng Huang, Anthony J Bilotta, Leiqi Xu, Yao Lu, Jiaren Sun, Fan Pan, Jia Zhou, Wenbo Zhang, Suxia Yao, Craig L Maynard, Nagendra Singh, Sara M Dann, Zhan Ju Liu, Yingzi Cong
Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nature communications 11 (1) (2020)
Zhi-Qing Liu, Haiying Chen, Pingyuan Wang, Yi Li, Eric A Wold, Paul G Leonard, Sarah Joseph, Allan R Brasier, Bing Tian, Jia Zhou
Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffold Hopping, Optimization, and Pharmacological Evaluation. Journal of medicinal chemistry 63 (10) (2020)
Eric A Wold, Erik J Garcia, Christopher T Wild, Joanna M Miszkiel, Claudia A Soto, Jianping Chen, Konrad Pazdrak, Robert G Fox, Noelle C Anastasio, Katherine A Cunningham, Jia Zhou
Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT2C Receptor-Positive Allosteric Modulators with Enhanced Drug-like Properties. Journal of medicinal chemistry 63 (14) (2020)
Pingyuan Wang, Daniel E Felsing, Haiying Chen, Sonja J Stutz, Ryan E Murphy, Katherine A Cunningham, John A Allen, Jia Zhou
Discovery of Potent and Brain-Penetrant GPR52 Agonist that Suppresses Psychostimulant Behavior. Journal of medicinal chemistry 63 (22) (2020)
Jimin Xu, Pei-Yong Shi, Hongmin Li, Jia Zhou
Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential. ACS infectious diseases 6 (5) (2020)
Jimin Xu, Judith Berastegui-Cabrera, Na Ye, Marta Carretero-Ledesma, Jerónimo Pachón-Díaz, Haiying Chen, Maria Eugenia Pachón-Ibáñez, Javier Sánchez-Céspedes, Jia Zhou
Discovery of Novel Substituted N-(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors. Journal of medicinal chemistry 63 (21) (2020)
Jimin Xu, Xuping Xie, Na Ye, Jing Zou, Haiying Chen, Mark A White, Pei-Yong Shi, Jia Zhou
Design, Synthesis, and Biological Evaluation of Substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5-b]pyridine-7,3'-indoline]-2',5(3H)-dione Analogues as Potent NS4B Inhibitors for the Treatment of Dengue Virus Infection. Journal of medicinal chemistry 62 (17) (2019)
Jia Zhou, Katherine A Cunningham
Positive-allosteric modulation of the 5-HT2C receptor: implications for neuropsychopharmacology and neurotherapeutics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 44 (1) (2019)
Jimin Xu, Eric A Wold, Ye Ding, Qiang Shen, Jia Zhou
Therapeutic Potential of Oridonin and Its Analogs: From Anticancer and Antiinflammation to Neuroprotection. Molecules (Basel, Switzerland) 23 (2) (2018)
Claire B Cummins, Xiaofu Wang, Omar Nunez Lopez, Gabriel Graham, Hong-Yan Tie, Jia Zhou, Ravi S Radhakrishnan
Luteolin-Mediated Inhibition of Hepatic Stellate Cell Activation via Suppression of the STAT3 Pathway. International journal of molecular sciences 19 (6) (2018)
Ye Ding, Dengfeng Li, Chunyong Ding, Pingyuan Wang, Zhiqing Liu, Eric A Wold, Na Ye, Haiying Chen, Mark A White, Qiang Shen, Jia Zhou
Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads. Journal of medicinal chemistry 61 (7) (2018)
Na Ye, Bang Li, Qi Mao, Eric A Wold, Sheng Tian, John A Allen, Jia Zhou
Orphan Receptor GPR88 as an Emerging Neurotherapeutic Target. ACS chemical neuroscience 10 (1) (2018)
Syed R Ali, Zhiqing Liu, Miroslav N Nenov, Oluwarotimi Folorunso, Aditya Singh, Federico Scala, Haiying Chen, T F James, Musaad Alshammari, Neli I Panova-Elektronova, Mark Andrew White, Jia Zhou, Fernanda Laezza
Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic. ACS chemical neuroscience 9 (5) (2018)
Aleksandra Drelich, Barbara Judy, Xi He, Qing Chang, Shangyi Yu, Xiang Li, Fanglin Lu, Maki Wakamiya, Vsevolod Popov, Jia Zhou, Thomas Ksiazek, Bin Gong
Exchange Protein Directly Activated by cAMP Modulates Ebola Virus Uptake into Vascular Endothelial Cells. Viruses 10 (10) (2018)
Eric A Wold, Jianping Chen, Katherine A Cunningham, Jia Zhou
Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts. Journal of medicinal chemistry 62 (1) (2018)
Christopher T Wild, Joanna M Miszkiel, Eric A Wold, Claudia A Soto, Chunyong Ding, Rachel M Hartley, Mark A White, Noelle C Anastasio, Katherine A Cunningham, Jia Zhou
Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor. Journal of medicinal chemistry 62 (1) (2018)
Zhiqing Liu, Pingyuan Wang, Haiying Chen, Eric A Wold, Bing Tian, Allan R Brasier, Jia Zhou
Drug Discovery Targeting Bromodomain-Containing Protein 4. Journal of medicinal chemistry 60 (11) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jia Zhou