John M Kelly

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 27

Top Venues

PLoS neglected tropical diseases

Nature communications

Science (New York, N.Y.)

ACS infectious diseases

London School of Hygiene and Tropical Medicine

This page only lists publications with an associated author ORCID identifier.

Affiliation History

London School of Hygiene and Tropical Medicine

United Kingdom

Professor of Molecular Biology :: Pathogen Molecular Biology

Publications

Francisco Olmo, Shiromani Jayawardhana, Archie A Khan, Harry C Langston, Amanda Fortes Francisco, Richard L Atherton, Alex I Ward, Martin C Taylor, John M Kelly, Michael D Lewis
A panel of phenotypically and genotypically diverse bioluminescent:fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research. PLoS neglected tropical diseases 18 (5) (2024)
Francisco Olmo, Shiromani Jayawardhana, Archie A Khan, Harry C Langston, Amanda Fortes Francisco, Richard L Atherton, Alex I Ward, Martin C Taylor, John M Kelly, Michael D Lewis
A panel of phenotypically and genotypically diverse bioluminescent:fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research. PLoS neglected tropical diseases 18 (5) (2024)
Archie A Khan, Harry C Langston, Louis Walsh, Rebecca Roscoe, Shiromani Jayawardhana, Amanda Fortes Francisco, Martin Craig Taylor, Conor J McCann, John M Kelly, Michael D Lewis
Enteric nervous system regeneration and functional cure of experimental digestive Chagas disease with trypanocidal chemotherapy. Nature communications 15 (1) (2024)
George Fytas, Grigoris Zoidis, Antonios Drakopoulos, Martin Craig Taylor, John M Kelly, Alexandra Tsatsaroni, Andrew Tsotinis
New Lipophilic Hydroxamates as Promising Trypanocidal Agents: Design, Synthesis, SAR, and Conformational Behavior Studies. ACS medicinal chemistry letters 15 (7) (2024)
George Fytas, Grigoris Zoidis, Antonios Drakopoulos, Martin Craig Taylor, John M Kelly, Alexandra Tsatsaroni, Andrew Tsotinis
New Lipophilic Hydroxamates as Promising Trypanocidal Agents: Design, Synthesis, SAR, and Conformational Behavior Studies. ACS medicinal chemistry letters 15 (7) (2024)
Archie A Khan, Harry C Langston, Louis Walsh, Rebecca Roscoe, Shiromani Jayawardhana, Amanda Fortes Francisco, Martin Craig Taylor, Conor J McCann, John M Kelly, Michael D Lewis
Enteric nervous system regeneration and functional cure of experimental digestive Chagas disease with trypanocidal chemotherapy. Nature communications 15 (1) (2024)
Nathan Trometer, Jérémy Pecourneau, Liwen Feng, José A Navarro-Huerta, Danielle Lazarin-Bidóia, Sueli de Oliveira Silva Lautenschlager, Louis Maes, Amanda Fortes Francisco, John M Kelly, Brigitte Meunier, Monica Cal, Pascal Mäser, Marcel Kaiser, Elisabeth Davioud-Charvet
Synthesis and Anti-Chagas Activity Profile of a Redox-Active Lead 3-Benzylmenadione Revealed by High-Content Imaging. ACS infectious diseases 10 (5) (2024)
Francisco Olmo, Shiromani Jayawardhana, Archie A Khan, Harry C Langston, Amanda Fortes Francisco, Richard L Atherton, Alex I Ward, Martin C Taylor, John M Kelly, Michael D Lewis
A panel of phenotypically and genotypically diverse bioluminescent:fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research. PLoS neglected tropical diseases 18 (5) (2024)
Nathan Trometer, Jérémy Pecourneau, Liwen Feng, José A Navarro-Huerta, Danielle Lazarin-Bidóia, Sueli de Oliveira Silva Lautenschlager, Louis Maes, Amanda Fortes Francisco, John M Kelly, Brigitte Meunier, Monica Cal, Pascal Mäser, Marcel Kaiser, Elisabeth Davioud-Charvet
Synthesis and Anti-Chagas Activity Profile of a Redox-Active Lead 3-Benzylmenadione Revealed by High-Content Imaging. ACS infectious diseases (2024)
Archie A Khan, Harry C Langston, Louis Walsh, Rebecca Roscoe, Shiromani Jayawardhana, Amanda Fortes Francisco, Martin Craig Taylor, Conor J McCann, John M Kelly, Michael D Lewis
Enteric nervous system regeneration and functional cure of experimental digestive Chagas disease with trypanocidal chemotherapy. Nature communications 15 (1) (2024)
Francisco Olmo, Shiromani Jayawardhana, Archie A Khan, Harry C Langston, Amanda Fortes Francisco, Richard L Atherton, Alex I Ward, Martin C Taylor, John M Kelly, Michael D Lewis
A panel of phenotypically and genotypically diverse bioluminescent:fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research. PLoS neglected tropical diseases 18 (5) (2024)
Nathan Trometer, Jérémy Pecourneau, Liwen Feng, José A Navarro-Huerta, Danielle Lazarin-Bidóia, Sueli de Oliveira Silva Lautenschlager, Louis Maes, Amanda Fortes Francisco, John M Kelly, Brigitte Meunier, Monica Cal, Pascal Mäser, Marcel Kaiser, Elisabeth Davioud-Charvet
Synthesis and Anti-Chagas Activity Profile of a Redox-Active Lead 3-Benzylmenadione Revealed by High-Content Imaging. ACS infectious diseases 10 (5) (2024)
Srinivasa P S Rao, Matthew K Gould, Jonas Noeske, Jeremy C Mottram, Rajiv S Jumani, Pearly Shuyi Ng, Olivier René, Yen-Liang Chen, Marcel Kaiser, Ryan Ritchie, Amanda Fortes Francisco, Nila Johnson, Debjani Patra, Harry Cheung, Colin Deniston, Andreas D Schenk, Wilian A Cortopassi, Remo S Schmidt, Natalie Wiedemar, Bryanna Thomas, Rima Palkar, Nahdiyah A Ghafar, Vanessa Manoharan, Catherine Luu, Jonathan E Gable, Kah Fei Wan, Elmarie Myburgh, Jeremy Charles Mottram, S Whitney Barnes, John R Walker, Charles A Wartchow, Natasha Aziz, Colin Osborne, Juergen Wagner, Christopher Sarko, John M Kelly, Ujjini H Manjunatha, Pascal Mäser, Jan Jiricek, Suresh B Lakshminarayana, Michael P Barrett, Thierry Tidiane Diagana
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science (New York, N.Y.) 380 (6652) (2023)
Livio Racané, Lucija Ptiček, Sanja Kostrun, Silvana Raić-Malić, Martin Craig Taylor, Michael J Delves, Sam Alsford, Francisco Olmo, Amanda Fortes Francisco, John M Kelly
Bis-6-amidino-benzothiazole Derivative that Cures Experimental Stage 1 African Trypanosomiasis with a Single Dose. Journal of medicinal chemistry (2023)
Srinivasa P S Rao, Matthew K Gould, Jonas Noeske, Jeremy C Mottram, Rajiv S Jumani, Pearly Shuyi Ng, Olivier René, Yen-Liang Chen, Marcel Kaiser, Ryan Ritchie, Amanda Fortes Francisco, Nila Johnson, Debjani Patra, Harry Cheung, Colin Deniston, Andreas D Schenk, Wilian A Cortopassi, Remo S Schmidt, Natalie Wiedemar, Bryanna Thomas, Rima Palkar, Nahdiyah A Ghafar, Vanessa Manoharan, Catherine Luu, Jonathan E Gable, Kah Fei Wan, Elmarie Myburgh, Jeremy Charles Mottram, S Whitney Barnes, John R Walker, Charles A Wartchow, Natasha Aziz, Colin Osborne, Juergen Wagner, Christopher Sarko, John M Kelly, Ujjini H Manjunatha, Pascal Mäser, Jan Jiricek, Suresh B Lakshminarayana, Michael P Barrett, Thierry Tidiane Diagana
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science (New York, N.Y.) 380 (6652) (2023)
Srinivasa P S Rao, Matthew K Gould, Jonas Noeske, Jeremy C Mottram, Rajiv S Jumani, Pearly Shuyi Ng, Olivier René, Yen-Liang Chen, Marcel Kaiser, Ryan Ritchie, Amanda Fortes Francisco, Nila Johnson, Debjani Patra, Harry Cheung, Colin Deniston, Andreas D Schenk, Wilian A Cortopassi, Remo S Schmidt, Natalie Wiedemar, Bryanna Thomas, Rima Palkar, Nahdiyah A Ghafar, Vanessa Manoharan, Catherine Luu, Jonathan E Gable, Kah Fei Wan, Elmarie Myburgh, Jeremy Charles Mottram, S Whitney Barnes, John R Walker, Charles A Wartchow, Natasha Aziz, Colin Osborne, Juergen Wagner, Christopher Sarko, John M Kelly, Ujjini H Manjunatha, Pascal Mäser, Jan Jiricek, Suresh B Lakshminarayana, Michael P Barrett, Thierry Tidiane Diagana
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science (New York, N.Y.) 380 (6652) (2023)
Shiromani Jayawardhana, Alexander I Ward, Amanda F Francisco, Michael D Lewis, Martin C Taylor, John M Kelly, Francisco Olmo
Benznidazole treatment leads to DNA damage in Trypanosoma cruzi and the persistence of rare widely dispersed non-replicative amastigotes in mice. PLoS pathogens 19 (11) (2023)
Silvia González, Richard J Wall, John Thomas, Stéphanie Braillard, Gino Brunori, Isabel Camino, Juan Cantizani, Sandra Carvalho, Pablo Castañeda Casado, Eric Chatelain, Ignacio Cotillo, Jose M Fiandor, Amanda Fortes Francisco, David Grimsditch, Martine Keenan, John M Kelly, Albane Kessler, Chiara Luise, Jonathan J Lyon, Lorna M MacLean, Maria Marco, J Julio Martin, María Santos Martínez, Christy Paterson, Kevin D Read, Angel Santos-Villarejo, Fabio Zuccotto, Susan Wyllie, Timothy J Miles, Manu De Rycker
Short-course combination treatment for experimental chronic Chagas disease. Science translational medicine 15 (726) (2023)
Amanda Fortes Francisco, Ursula Saade, Shiromani Jayawardhana, Hans Pottel, Ivan Scandale, Eric Chatelain, Peter Liehl, John M Kelly, Maan Zrein
Comparing in vivo bioluminescence imaging and the Multi-Cruzi immunoassay platform to develop improved Chagas disease diagnostic procedures and biomarkers for monitoring parasitological cure. PLoS neglected tropical diseases 16 (10) (2022)
Archie A Khan, Harry C Langston, Fernanda Cristina Costa, Francisco Olmo, Martin Craig Taylor, Conor J McCann, John M Kelly, Michael D Lewis
Local association of Trypanosoma cruzi chronic infection foci and enteric neuropathic lesions at the tissue micro-domain scale. PLoS pathogens 17 (8) (2021)
Alexander I Ward, Michael D Lewis, Martin C Taylor, John M Kelly
Incomplete recruitment of protective T cells is associated with Trypanosoma cruzi persistence in the mouse colon. Infection and immunity (2021)
Alexander I Ward, Michael D Lewis, Archie A Khan, Conor J McCann, Amanda F Francisco, Shiromani Jayawardhana, Martin C Taylor, John M Kelly
In Vivo Analysis of Trypanosoma cruzi Persistence Foci at Single-Cell Resolution. mBio 11 (4) (2020)
Gurdip Singh Mann, Amanda F Francisco, Shiromani Jayawardhana, Martin C Taylor, Michael D Lewis, Francisco Olmo, Elisangela Oliveira de Freitas, Fabiana M S Leoratti, Cesar López-Camacho, Arturo Reyes-Sandoval, John M Kelly
Drug-cured experimental Trypanosoma cruzi infections confer long-lasting and cross-strain protection. PLoS neglected tropical diseases 14 (4) (2020)
Angeliki-Sofia Foscolos, Ioannis P Papanastasiou, Andrew Tsotinis, Martin Craig Taylor, John M Kelly
Synthesis and Evaluation of Nifurtimox-Adamantane Adducts with Trypanocidal Activity. ChemMedChem 14 (13) (2019)
Michael D Lewis, Amanda F Francisco, Shiromani Jayawardhana, Harry Langston, Martin Craig Taylor, John M Kelly
Imaging the development of chronic Chagas disease after oral transmission. Scientific reports 8 (1) (2018)
Mônica C Campos, Jody Phelan, Amanda F Francisco, Martin C Taylor, Michael D Lewis, Arnab Pain, Taane Gregory Clark, John M Kelly
Genome-wide mutagenesis and multi-drug resistance in American trypanosomes induced by the front-line drug benznidazole. Scientific reports 7 (1) (2017)
Kranti G Kishore, Ouldouz Ghashghaei, Carolina Estarellas, M Mar Mestre, Cristina Monturiol, Nicola Kielland, John M Kelly, Amanda Fortes Francisco, Shiromani Jayawardhana, Diego Muñoz-Torrero, Belén Pérez, Francisco Javier Luque, Rocío Gámez-Montaño, Rodolfo Lavilla
Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds. Angewandte Chemie (International ed. in English) 55 (31) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

John M Kelly