Jonathan L Chen

Publication Activity (10 Years)

Years Active: 2017-2021
Publications (10 Years): 7

Top Topics

Quality Control

Duchenne Muscular Dystrophy

High Throughput Sequencing

Top Venues

ACS chemical biology

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Sarah Wagner-Griffin, Masahito Abe, Raphael I Benhamou, Alicia J Angelbello, Kamalakannan Vishnu, Jonathan L Chen, Jessica L Childs-Disney, Matthew D Disney
A Druglike Small Molecule that Targets r(CCUG) Repeats in Myotonic Dystrophy Type 2 Facilitates Degradation by RNA Quality Control Pathways. Journal of medicinal chemistry 64 (12) (2021)
Jessica A Bush, Haruo Aikawa, Rita Fuerst, Yue Li, Andrei Ursu, Samantha M Meyer, Raphael I Benhamou, Jonathan L Chen, Tanya Khan, Sarah Wagner-Griffin, Montina J Van Meter, Yuquan Tong, Hailey Olafson, Kendra K McKee, Jessica L Childs-Disney, Tania F Gendron, Yong-Jie Zhang, Alyssa N Coyne, Eric T Wang, Ilyas Yildirim, Kye Won Wang, Leonard Petrucelli, Jeffrey D Rothstein, Matthew D Disney
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models. Science translational medicine 13 (617) (2021)
Jonathan L Chen, Peiyuan Zhang, Masahito Abe, Haruo Aikawa, Liying Zhang, Alexander J Frank, Timothy Zembryski, Christopher Hubbs, HaJeung Park, Jane Withka, Claire Steppan, Lucy Rogers, Shawn Cabral, Martin Pettersson, Travis T Wager, Matthew A Fountain, Gavin Rumbaugh, Jessica L Childs-Disney, Matthew D Disney
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. Journal of the American Chemical Society 142 (19) (2020)
Andrei Ursu, Kye Won Wang, Jessica A Bush, Shruti Choudhary, Jonathan L Chen, Jared T Baisden, Yong-Jie Zhang, Tania F Gendron, Leonard Petrucelli, Ilyas Yildirim, Matthew D Disney
Structural Features of Small Molecules Targeting the RNA Repeat Expansion That Causes Genetically Defined ALS/FTD. ACS chemical biology 15 (12) (2020)
Jonathan L Chen, Walter N Moss, Adam Spencer, Peiyuan Zhang, Jessica L Childs-Disney, Matthew D Disney
The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology. PloS one 14 (7) (2019)
Alicia J Angelbello, Jonathan L Chen, Jessica L Childs-Disney, Peiyuan Zhang, Zi-Fu Wang, Matthew D Disney
Using Genome Sequence to Enable the Design of Medicines and Chemical Probes. Chemical reviews 118 (4) (2018)
Jonathan L Chen, Damian M VanEtten, Matthew A Fountain, Ilyas Yildirim, Matthew D Disney
Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1. Biochemistry 56 (27) (2017)