Jeffrey D Rothstein (Jeffrey Rothstein)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 25

Top Venues

Scientific data

Nature neuroscience

Science translational medicine

Nucleus (Austin, Tex.)

Johns Hopkins University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Johns Hopkins University Jul 01 1986

United States

Director, Brain Science Institute :: Neurology

Publications

Charlotte M Fare, Jeffrey D Rothstein
Nuclear pore dysfunction and disease: a complex opportunity. Nucleus (Austin, Tex.) 15 (1) (2024)
Charlotte M Fare, Jeffrey D Rothstein
Nuclear pore dysfunction and disease: a complex opportunity. Nucleus (Austin, Tex.) 15 (1) (2024)
Charlotte M Fare, Jeffrey D Rothstein
Nuclear pore dysfunction and disease: a complex opportunity. Nucleus (Austin, Tex.) 15 (1) (2024)
Emily G Thompson, Olivia Spead, S Can Akerman, Carrie Curcio, Benjamin L Zaepfel, Erica R Kent, Thomas Philips, Balaji G Vijayakumar, Anna Zacco, Weibo Zhou, Guhan Nagappan, Jeffrey D Rothstein
A robust evaluation of TDP-43, poly GP, cellular pathology and behavior in a AAV-C9ORF72 (G 4 C 2 ) 66 mouse model. bioRxiv : the preprint server for biology (2024)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Olivia Spead, Benjamin L Zaepfel, Jeffrey D Rothstein
Nuclear Pore Dysfunction in Neurodegeneration. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 19 (4) (2022)
Alyssa N Coyne, Jeffrey D Rothstein
Nuclear pore complexes - a doorway to neural injury in neurodegeneration. Nature reviews. Neurology 18 (6) (2022)
Nicholas J Maragakis, Jeffrey D Rothstein
The Evolving Landscape of Motor Neuron Disease Therapeutics. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 19 (4) (2022)
Junli Gao, Quinlan T Mewborne, Amandeep Girdhar, Udit Sheth, Alyssa N Coyne, Ritika Punathil, Bong Gu Kang, Morgan Dasovich, Austin M Veire, Mariely DeJesus Hernandez, Shuaichen Liu, Zheng Shi, Ruxandra Dafinca, Elise Fouquerel, Kevin Talbot, Tae-In Kam, Yong-Jie Zhang, Gourisankar Ghosh, Leonard Petrucelli, Marka van Blitterswijk, Lin Guo, Ted M Dawson, Valina L Dawson, Anthony K L Leung, Thomas E Lloyd, Tania F Gendron, Jeffrey D Rothstein, Ke Zhang
Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins. Science translational medicine 14 (662) (2022)
Emily G Baxi, Terri Thompson, Jonathan Li, Julia A Kaye, Ryan G Lim, Jie Wu, Divya Ramamoorthy, Leandro Lima, Vineet Vaibhav, Andrea Matlock, Aaron Frank, Alyssa N Coyne, Barry Landin, Loren Ornelas, Elizabeth Mosmiller, Sara Thrower, S Michelle Farr, Lindsey Panther, Emilda Gomez, Erick Galvez, Daniel Perez, Imara Meepe, Susan Lei, Berhan Mandefro, Hannah Trost, Louis Pinedo, Maria G Banuelos, Chunyan Liu, Ruby Moran, Veronica Garcia, Michael Workman, Ritchie Ho, Stacia Wyman, Jennifer Roggenbuck, Matthew B Harms, Jennifer Stocksdale, Ricardo Miramontes, Keona Wang, Vidya Venkatraman, Ronald Holewenski, Niveda Sundararaman, Rakhi Pandey, Danica-Mae Manalo, Aneesh Donde, Nhan Huynh, Miriam Adam, Brook T Wassie, Edward Vertudes, Naufa Amirani, Krishna Raja, Reuben Thomas, Lindsey Hayes, Alex Lenail, Aianna Cerezo, Sarah Luppino, Alanna Farrar, Lindsay Pothier, Carolyn Prina, Todd Morgan, Arish Jamil, Sarah Heintzman, Jennifer Jockel-Balsarotti, Elizabeth Karanja, Jesse Markway, Molly McCallum, Ben Joslin, Deniz Alibazoglu, Stephen J Kolb, Senda Ajroud-Driss, Robert H Baloh, Daragh Heitzman, Tim Miller, Jonathan D Glass, Natasha Leanna Patel-Murray, Hong Yu, Ervin Sinani, Prasha Vigneswaran, Alexander V Sherman, Omar Ahmad, Promit Roy, Jay C Beavers, Steven Zeiler, John W Krakauer, Carla Agurto, Guillermo A Cecchi, Mary Bellard, Yogindra Raghav, Karen Sachs, Tobias Ehrenberger, Elizabeth Bruce, Merit E Cudkowicz, Nicholas J Maragakis, Raquel Norel, Jennifer E Van Eyk, Steven Finkbeiner, James Berry, Dhruv Sareen, Leslie M Thompson, Ernest Fraenkel, Clive N Svendsen, Jeffrey D Rothstein
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines. Nature neuroscience 25 (2) (2022)
Shaopeng Wang, Malgorzata J Latallo, Zhe Zhang, Bo Huang, Dmitriy G Bobrovnikov, Daoyuan Dong, Nathan M Livingston, Wilson Tjoeng, Lindsey R Hayes, Jeffrey D Rothstein, Lyle W Ostrow, Bin Wu, Shuying Sun
Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD. Nature communications 12 (1) (2021)
Alyssa N Coyne, Jeffrey D Rothstein
The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei. Acta neuropathologica communications 9 (1) (2021)
Alyssa N Coyne, Jeffrey D Rothstein
Nuclear lamina invaginations are not a pathological feature of C9orf72 ALS/FTD. Acta neuropathologica communications 9 (1) (2021)
Carole Escartin, Elena Galea, András Lakatos, James P O'Callaghan, Gabor C Petzold, Alberto Serrano-Pozo, Christian Steinhäuser, Andrea Volterra, Giorgio Carmignoto, Amit Agarwal, Nicola J Allen, Alfonso Araque, Luis Barbeito, Ari Barzilai, Dwight E Bergles, Gilles Bonvento, Arthur Morgan Butt, Wei-Ting Chen, Martine Cohen-Salmon, Colm Cunningham, Benjamin Deneen, Bart De Strooper, Blanca Díaz-Castro, Cinthia Farina, Marc Freeman, Vittorio Gallo, James E Goldman, Steven A Goldman, Magdalena Götz, Antonia Gutierrez, Philip G Haydon, Dieter Henrik Heiland, Elly M Hol, Matthew G Holt, Masamitsu Iino, Ksenia V Kastanenka, Helmut Kettenmann, Baljit S Khakh, Schuichi Koizumi, C Justin Lee, Shane A Liddelow, Brian A MacVicar, Pierre Magistretti, Albee Messing, Anusha Mishra, Anna Victoria Molofsky, Keith K Murai, Christopher M Norris, Seiji Okada, Stéphane H R Oliet, João Filipe Oliveira, Aude Panatier, Vladimir Parpura, Marcela Pekna, Milos Pekny, Luc Pellerin, Gertrudis Perea, Beatriz G Pérez-Nievas, Frank W Pfrieger, Kira E Poskanzer, Francisco J Quintana, Richard M Ransohoff, Miriam Riquelme-Perez, Stefanie Robel, Christine R Rose, Jeffrey D Rothstein, Nathalie Rouach, David H Rowitch, Alexey V Semyanov, Swetlana Sirko, Harald Sontheimer, Raymond A Swanson, Javier Vitorica, Ina-Beate Wanner, Levi B Wood, Jiaqian Wu, Binhai Zheng, Eduardo R Zimmer, Robert Zorec, Michael V Sofroniew, Alexei Verkhratsky
Reactive astrocyte nomenclature, definitions, and future directions. Nature neuroscience 24 (3) (2021)
Jessica A Bush, Haruo Aikawa, Rita Fuerst, Yue Li, Andrei Ursu, Samantha M Meyer, Raphael I Benhamou, Jonathan L Chen, Tanya Khan, Sarah Wagner-Griffin, Montina J Van Meter, Yuquan Tong, Hailey Olafson, Kendra K McKee, Jessica L Childs-Disney, Tania F Gendron, Yong-Jie Zhang, Alyssa N Coyne, Eric T Wang, Ilyas Yildirim, Kye Won Wang, Leonard Petrucelli, Jeffrey D Rothstein, Matthew D Disney
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models. Science translational medicine 13 (617) (2021)
McLane J Watson, Paolo D A Vignali, Steven J Mullett, Abigail E Overacre-Delgoffe, Ronal M Peralta, Stephanie Grebinoski, Ashley V Menk, Natalie L Rittenhouse, Kristin DePeaux, Ryan D Whetstone, Dario A A Vignali, Timothy W Hand, Amanda C Poholek, Brett M Morrison, Jeffrey D Rothstein, Stacy G Wendell, Greg M Delgoffe
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid. Nature 591 (7851) (2021)
Alyssa N Coyne, Victoria Baskerville, Benjamin L Zaepfel, Gourisankar Ghosh, Frank Rigo, C Frank Bennett, C Patrick Lusk, Jeffrey D Rothstein
Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS. Science translational medicine 13 (604) (2021)
Sean J Miller, Thomas Philips, Namho Kim, Raha Dastgheyb, Zhuoxun Chen, Yi-Chun Hsieh, J Gavin Daigle, Malika Datta, Jeannie Chew, Svetlana Vidensky, Jacqueline T Pham, Ethan G Hughes, Michael B Robinson, Rita Sattler, Raju Tomer, Jung Soo Suk, Dwight E Bergles, Norman Haughey, Mikhail Pletnikov, Justin Hanes, Jeffrey D Rothstein
Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin. Nature neuroscience 22 (5) (2019)
Mithilesh Kumar Jha, Youngjin Lee, Katelyn A Russell, Fang Yang, Raha M Dastgheyb, Pragney Deme, Xanthe H Ament, Weiran Chen, Ying Liu, Yun Guan, Michael J Polydefkis, Ahmet Hoke, Norman J Haughey, Jeffrey D Rothstein, Brett M Morrison
Monocarboxylate transporter 1 in Schwann cells contributes to maintenance of sensory nerve myelination during aging. Glia 68 (1) (2019)
Ekaterina Savchenko, Gabriel N Teku, Antonio Boza-Serrano, Kaspar Russ, Manon Berns, Tomas Deierborg, Nuno J Lamas, Hynek Wichterle, Jeffrey D Rothstein, Christopher E Henderson, Mauno Vihinen, Laurent Roybon
FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes. Scientific reports 9 (1) (2019)
Yong-Jie Zhang, Tania F Gendron, Jonathan C Grima, Hiroki Sasaguri, Karen Jansen-West, Ya-Fei Xu, Rebecca B Katzman, Jennifer Gass, Melissa E Murray, Mitsuru Shinohara, Wen-Lang Lin, Aliesha Garrett, Jeannette N Stankowski, Lillian Daughrity, Jimei Tong, Emilie A Perkerson, Mei Yue, Jeannie Chew, Monica Castanedes-Casey, Aishe Kurti, Zizhao S Wang, Amanda M Liesinger, Jeremy D Baker, Jie Jiang, Clotilde Lagier-Tourenne, Dieter Edbauer, Don W Cleveland, Rosa Rademakers, Kevin B Boylan, Guojun Bu, Christopher D Link, Chad A Dickey, Jeffrey D Rothstein, Gourisankar Ghosh, John D Fryer, Leonard Petrucelli
C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins. Nature neuroscience 19 (5) (2016)

Jeffrey D Rothstein.css-eqlu8i{font-size:small;padding-left:4px;} (Jeffrey Rothstein)

Publication Activity (10 Years)

Top Topics

Top Venues

Jeffrey D Rothstein (Jeffrey Rothstein)