Jörn Weisner (J Weisner)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 14

Top Topics

Molecular Dynamics

Epithelial Mesenchymal Transition

Structure Activity Relationship

Top Venues

Nature communications

RSC medicinal chemistry

Journal of medicinal chemistry

Angewandte Chemie (International ed. in English)

This page only lists publications with an associated author ORCID identifier.

Publications

Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Kosmas Alexandros Pervanidis, Giovanni Danilo D'Angelo, Jörn Weisner, Sven Brandherm, Daniel Rauh
Akt Inhibitor Advancements: From Capivasertib Approval to Covalent-Allosteric Promises. Journal of medicinal chemistry 67 (8) (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Kosmas Alexandros Pervanidis, Giovanni Danilo D'Angelo, Jörn Weisner, Sven Brandherm, Daniel Rauh
Akt Inhibitor Advancements: From Capivasertib Approval to Covalent-Allosteric Promises. Journal of medicinal chemistry (2024)
Alina Teuber, Tom Schulz, B S Fletcher, Rajesh Gontla, Thomas Mühlenberg, M-L Zischinsky, Janina Niggenaber, Jörn Weisner, S B Kleinbölting, Jonas Lategahn, Sonja Sievers, Matthias Philipp Müller, Sebastian Bauer, Daniel Rauh
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA. Nature communications 15 (1) (2024)
Juliane Stehle, Jörn Weisner, Leanne Eichhorn, Daniel Rauh, Malte Drescher
Insights into the Conformational Plasticity of the Protein Kinase Akt1 by Multi-Lateral Dipolar Spectroscopy. Chemistry (Weinheim an der Bergstrasse, Germany) (2023)
Shubhendu Palei, Jörn Weisner, Melina Vogt, Rajesh Gontla, Benjamin C Buchmuller, Christiane Ehrt, Tobias Grabe, Silke Kleinbölting, Matthias Philipp Müller, Guido H Clever, Daniel Rauh, Daniel Summerer
A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven translocation dioxygenase 2. RSC medicinal chemistry 13 (12) (2022)
Shubhendu Palei, Jörn Weisner, Melina Vogt, Rajesh Gontla, Benjamin C Buchmuller, Christiane Ehrt, Tobias Grabe, Silke Kleinbölting, Matthias Philipp Müller, Guido H Clever, Daniel Rauh, Daniel Summerer
A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven translocation dioxygenase 2. RSC medicinal chemistry 13 (12) (2022)
Lena Quambusch, Laura Depta, Ina Landel, Melissa Lubeck, Tonia Kirschner, Jonas Nabert, Niklas Uhlenbrock, Jörn Weisner, Michael Kostka, Laura M Levy, Carsten Schultz-Fademrecht, Franziska Glanemann, Kristina Althoff, Matthias P Müller, Jens Thomas Siveke, Daniel Rauh
Cellular model system to dissect the isoform-selectivity of Akt inhibitors. Nature communications 12 (1) (2021)
Patrick Roser, Jörn Weisner, Juliane Stehle, Daniel Rauh, Malte Drescher
Conformational selection vs. induced fit: insights into the binding mechanisms of p38α MAP Kinase inhibitors. Chemical communications (Cambridge, England) 56 (62) (2021)
Niklas Uhlenbrock, Steven Smith, Jörn Weisner, Ina Landel, Marius Lindemann, Thien Anh Le, Julia Hardick, Rajesh Gontla, Rebekka Scheinpflug, Paul Czodrowski, Petra Janning, Laura Depta, Lena Quambusch, Matthias Philipp Müller, Bernd Engels, Daniel Rauh
Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt. Chemical science 10 (12) (2019)
Jörn Weisner, Ina Landel, Christoph Reintjes, Niklas Uhlenbrock, Marija Trajkovic-Arsic, Niklas Dienstbier, Julia Hardick, Swetlana Ladigan, Marius Lindemann, Steven Smith, Lena Quambusch, Rebekka Scheinpflug, Laura Depta, Rajesh Gontla, Anke Unger, Matthias Philipp Müller, Matthias Baumann, Carsten Schultz-Fademrecht, Georgia Günther, Abdelouahid Maghnouj, Michael Pohl, Christian Teschendorf, Heiner Wolters, Richard Viebahn, Andrea Tannapfel, Waldemar Uhl, Jan G Hengstler, Stephan A Hahn, Jens Thomas Siveke, Daniel Rauh
Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer. Cancer research 79 (9) (2019)
Lena Quambusch, Ina Landel, Laura Depta, Jörn Weisner, Niklas Uhlenbrock, Matthias P Müller, Franziska Glanemann, Kristina Althoff, Jens Thomas Siveke, Daniel Rauh
Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity. Angewandte Chemie (International ed. in English) 58 (52) (2019)