Joshua N Farr

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 35

Top Topics

Postmenopausal Women

Endoplasmic Reticulum

Top Venues

bioRxiv : the preprint server for biology

Calcified tissue international

Nature communications

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

This page only lists publications with an associated author ORCID identifier.

Publications

Mitchell N Froemming, Sundeep Khosla, Joshua N Farr
Marrow Adipocyte Senescence in the Pathogenesis of Bone Loss. Current osteoporosis reports (2024)
Stella Victorelli, Hanna Salmonowicz, James Chapman, Helene Martini, Maria Grazia Vizioli, Joel S Riley, Catherine Cloix, Ella Hall-Younger, Jair Machado Espindola-Netto, Diana Jurk, Anthony B Lagnado, Lilian Sales Gomez, Joshua N Farr, Dominik Saul, Rebecca Reed, George Kelly, Madeline Eppard, Laura C Greaves, Zhixun Dou, Nicholas Pirius, Karolina Szczepanowska, Rebecca A Porritt, Huijie Huang, Timothy Y Huang, Derek A Mann, Claudio Akio Masuda, Sundeep Khosla, Haiming Dai, Scott H Kaufmann, Emmanouil Zacharioudakis, Evripidis Gavathiotis, Nathan K LeBrasseur, Xue Lei, Alva G Sainz, Viktor I Korolchuk, Peter D Adams, Gerald S Shadel, Stephen W G Tait, João F Passos
Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature (2024)
Joshua N Farr, Elizabeth J Atkinson, Sara J Achenbach, Tammie L Volkman, Amanda J Tweed, Stephanie J Vos, Ming Ruan, Jad G Sfeir, Matthew T Drake, Dominik Saul, Madison L Doolittle, Irina Bancos, Kai Yu, Tamara Tchkonia, Nathan K LeBrasseur, James L Kirkland, David G Monroe, Sundeep Khosla
Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial. Nature medicine (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Joshua N Farr
Cardiovascular Safety and Romosozumab - The Plot Thickens. The Journal of clinical endocrinology and metabolism (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Mitchell N Froemming, Sundeep Khosla, Joshua N Farr
Marrow Adipocyte Senescence in the Pathogenesis of Bone Loss. Current osteoporosis reports 22 (4) (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Pamela G Rufus-Membere, Kara L Holloway-Kew, Adolfo Diez-Perez, Natasha M Appelman-Dijkstra, Mary L Bouxsein, Erik F Eriksen, Joshua N Farr, Sundeep Khosla, Mark A Kotowicz, Xavier Nogues Y Solans, Mishaela Rubin, Julie A Pasco
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study. Calcified tissue international 112 (3) (2023)
Pamela G Rufus-Membere, Kara L Holloway-Kew, Adolfo Diez-Perez, Natasha M Appelman-Dijkstra, Mary L Bouxsein, Erik F Eriksen, Joshua N Farr, Sundeep Khosla, Mark A Kotowicz, Xavier Nogues Y Solans, Mishaela Rubin, Julie A Pasco
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study. Calcified tissue international (2023)
Stella Victorelli, Hanna Salmonowicz, James Chapman, Helene Martini, Maria Grazia Vizioli, Joel S Riley, Catherine Cloix, Ella Hall-Younger, Jair Machado Espindola-Netto, Diana Jurk, Anthony B Lagnado, Lilian Sales Gomez, Joshua N Farr, Dominik Saul, Rebecca Reed, George Kelly, Madeline Eppard, Laura C Greaves, Zhixun Dou, Nicholas Pirius, Karolina Szczepanowska, Rebecca A Porritt, Huijie Huang, Timothy Y Huang, Derek A Mann, Claudio Akio Masuda, Sundeep Khosla, Haiming Dai, Scott H Kaufmann, Emmanouil Zacharioudakis, Evripidis Gavathiotis, Nathan K LeBrasseur, Xue Lei, Alva G Sainz, Viktor I Korolchuk, Peter D Adams, Gerald S Shadel, Stephen W G Tait, João F Passos
Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature (2023)
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Stephanie J Vos, Kevin D Pavelko, Joshua N Farr, David G Monroe, Sundeep Khosla
Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton. Nature communications 14 (1) (2023)
Pamela G Rufus-Membere, Kara L Holloway-Kew, Adolfo Diez-Perez, Natasha M Appelman-Dijkstra, Mary L Bouxsein, Erik F Eriksen, Joshua N Farr, Sundeep Khosla, Mark A Kotowicz, Xavier Nogues Y Solans, Mishaela Rubin, Julie A Pasco
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study. Calcified tissue international (2023)
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Stephanie J Vos, Kevin D Pavelko, Joshua N Farr, David G Monroe, Sundeep Khosla
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton. bioRxiv : the preprint server for biology (2023)
Pamela G Rufus-Membere, Kara L Holloway-Kew, Adolfo Diez-Perez, Natasha M Appelman-Dijkstra, Mary L Bouxsein, Erik F Eriksen, Joshua N Farr, Sundeep Khosla, Mark A Kotowicz, Xavier Nogues Y Solans, Mishaela Rubin, Julie A Pasco
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study. Calcified tissue international 112 (3) (2023)
Madison L Doolittle, Brittany A Eckhardt, Stephanie J Vos, Sarah Grain, Jennifer L Rowsey, Ming Ruan, Dominik Saul, Joshua N Farr, Megan M Weivoda, Sundeep Khosla, David G Monroe
Modest Effects of Osteoclast-Specific ERα Deletion after Skeletal Maturity. JBMR plus 7 (10) (2023)
Pamela G Rufus-Membere, Kara L Holloway-Kew, Adolfo Diez-Perez, Natasha M Appelman-Dijkstra, Mary L Bouxsein, Erik F Eriksen, Joshua N Farr, Sundeep Khosla, Mark A Kotowicz, Xavier Nogues Y Solans, Mishaela Rubin, Julie A Pasco
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study. Calcified tissue international 112 (3) (2023)
Japneet Kaur, Dominik Saul, Madison L Doolittle, Joshua N Farr, Sundeep Khosla, David G Monroe
MicroRNA - 19a - 3p Decreases with Age in Mice and Humans and Inhibits Osteoblast Senescence. JBMR plus 7 (6) (2023)
Parinya Samakkarnthai, Dominik Saul, Lei Zhang, Zaira Aversa, Madison L Doolittle, Jad G Sfeir, Japneet Kaur, Elizabeth J Atkinson, James R Edwards, R Graham G Russell, Robert J Pignolo, James L Kirkland, Tamara Tchkonia, Laura J Niedernhofer, David G Monroe, Nathan K LeBrasseur, Joshua N Farr, Paul D Robbins, Sundeep Khosla
In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers. bioRxiv : the preprint server for biology (2023)
Pamela G Rufus-Membere, Kara L Holloway-Kew, Adolfo Diez-Perez, Natasha M Appelman-Dijkstra, Mary L Bouxsein, Erik F Eriksen, Joshua N Farr, Sundeep Khosla, Mark A Kotowicz, Xavier Nogues Y Solans, Mishaela Rubin, Julie A Pasco
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study. Calcified tissue international 112 (3) (2023)
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Stephanie J Vos, Kevin D Pavelko, Joshua N Farr, David G Monroe, Sundeep Khosla
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton. bioRxiv : the preprint server for biology (2023)
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Stephanie J Vos, Kevin D Pavelko, Joshua N Farr, David G Monroe, Sundeep Khosla
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton. bioRxiv : the preprint server for biology (2023)
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Brittany Eckhardt, Stephanie Vos, Sarah Grain, Kveta Kroupova, Ming Ruan, Megan Weivoda, Merry Jo Oursler, Joshua N Farr, David G Monroe, Sundeep Khosla
Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 37 (9) (2022)
Dominik Saul, Robyn Laura Kosinsky, Elizabeth J Atkinson, Madison L Doolittle, Xu Zhang, Nathan K LeBrasseur, Robert J Pignolo, Paul D Robbins, Laura J Niedernhofer, Yuji Ikeno, Diana Jurk, João F Passos, LaTonya J Hickson, Ailing Xue, David G Monroe, Tamara Tchkonia, James L Kirkland, Joshua N Farr, Sundeep Khosla
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues. Nature communications 13 (1) (2022)
Abhishek Chandra, Anthony B Lagnado, Joshua N Farr, Megan Schleusner, David G Monroe, Dominik Saul, João F Passos, Sundeep Khosla, Robert J Pignolo
Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescence. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 37 (5) (2022)
Ruben Aquino-Martinez, Brittany A Eckhardt, Jennifer L Rowsey, Daniel G Fraser, Sundeep Khosla, Joshua N Farr, David G Monroe
Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice. Journal of periodontology 92 (10) (2021)
Joshua N Farr, Japneet Kaur, Madison L Doolittle, Sundeep Khosla
Osteocyte Cellular Senescence. Current osteoporosis reports 18 (5) (2021)
Sundeep Khosla, Parinya Samakkarnthai, David G Monroe, Joshua N Farr
Update on the pathogenesis and treatment of skeletal fragility in type 2 diabetes mellitus. Nature reviews. Endocrinology 17 (11) (2021)
Dominik Saul, David G Monroe, Jennifer L Rowsey, Robyn Laura Kosinsky, Stephanie J Vos, Madison L Doolittle, Joshua N Farr, Sundeep Khosla
Modulation of fracture healing by the transient accumulation of senescent cells. eLife 10 (2021)
Megan M Weivoda, Chee Kian Chew, David G Monroe, Joshua N Farr, Elizabeth J Atkinson, Jennifer R Geske, Brittany Eckhardt, Brianne Thicke, Ming Ruan, Amanda J Tweed, Louise K McCready, Robert A Rizza, Aleksey Matveyenko, Moustapha Kassem, Thomas Levin Andersen, Adrian Vella, Matthew T Drake, Bart L Clarke, Merry Jo Oursler, Sundeep Khosla
Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism. Nature communications 11 (1) (2020)
Abhishek Chandra, Anthony B Lagnado, Joshua N Farr, David G Monroe, Sean Park, Christine Hachfeld, Tamar Tchkonia, James L Kirkland, Sundeep Khosla, João F Passos, Robert J Pignolo
Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 35 (6) (2020)
Sundeep Khosla, Joshua N Farr, Tamara Tchkonia, James L Kirkland
The role of cellular senescence in ageing and endocrine disease. Nature reviews. Endocrinology 16 (5) (2020)