Sundeep Khosla

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 67

Top Topics

Postmenopausal Women

Skeletal Muscle

Top Venues

bioRxiv : the preprint server for biology

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Nature reviews. Molecular cell biology

This page only lists publications with an associated author ORCID identifier.

Publications

Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Amit Kumar Dey, Ann Hertzel, Anthony Agudelo, Azucena Rocha, Bikem Soygur, Birgit Schilling, Chase M Carver, Cristina Aguayo-Mazzucato, Darren J Baker, David A Bernlohr, Diana Jurk, Dilyana B Mangarova, Ellen M Quardokus, Elizabeth Ann L Enninga, Elizabeth L Schmidt, Feng Chen, Francesca E Duncan, Francesco Cambuli, Gagandeep Kaur, George A Kuchel, Gung Lee, Heike E Daldrup-Link, Helene Martini, Hemali Phatnani, Iman M Al-Naggar, Irfan Rahman, Jia Nie, João F Passos, Jonathan C Silverstein, Judith Campisi, Julia Wang, Kanako Iwasaki, Karina Barbosa, Kay Metis, Kerem Nernekli, Laura J Niedernhofer, Li Ding, Lichao Wang, Lisa C Adams, Liu Ruiyang, Madison L Doolittle, Marcos G Teneche, Marissa J Schafer, Ming Xu, Mohammadjavad Hajipour, Mozhgan Boroumand, Nathan Basisty, Nicholas Sloan, Nikolai Slavov, Olena Kuksenko, Paul Robson, Paul T Gomez, Periklis Vasilikos, Peter D Adams, Priscila Carapeto, Quan Zhu, Ramalakshmi Ramasamy, Rolando Perez-Lorenzo, Rong Fan, Runze Dong, Ruth Rebecca Montgomery, Sadiya Shaikh, Sanja Vickovic, Shanshan Yin, Shoukai Kang, Sonja Suvakov, Sundeep Khosla, Vesna D Garovic, Vilas Menon, Yanxin Xu, Yizhe Song, Yousin Suh, Zhixun Dou, Nicola Neretti
SenNet recommendations for detecting senescent cells in different tissues. Nature reviews. Molecular cell biology (2024)
Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Amit Kumar Dey, Ann Hertzel, Anthony Agudelo, Azucena Rocha, Bikem Soygur, Birgit Schilling, Chase M Carver, Cristina Aguayo-Mazzucato, Darren J Baker, David A Bernlohr, Diana Jurk, Dilyana B Mangarova, Ellen M Quardokus, Elizabeth Ann L Enninga, Elizabeth L Schmidt, Feng Chen, Francesca E Duncan, Francesco Cambuli, Gagandeep Kaur, George A Kuchel, Gung Lee, Heike E Daldrup-Link, Helene Martini, Hemali Phatnani, Iman M Al-Naggar, Irfan Rahman, Jia Nie, João F Passos, Jonathan C Silverstein, Judith Campisi, Julia Wang, Kanako Iwasaki, Karina Barbosa, Kay Metis, Kerem Nernekli, Laura J Niedernhofer, Li Ding, Lichao Wang, Lisa C Adams, Liu Ruiyang, Madison L Doolittle, Marcos G Teneche, Marissa J Schafer, Ming Xu, Mohammadjavad Hajipour, Mozhgan Boroumand, Nathan Basisty, Nicholas Sloan, Nikolai Slavov, Olena Kuksenko, Paul Robson, Paul T Gomez, Periklis Vasilikos, Peter D Adams, Priscila Carapeto, Quan Zhu, Ramalakshmi Ramasamy, Rolando Perez-Lorenzo, Rong Fan, Runze Dong, Ruth Rebecca Montgomery, Sadiya Shaikh, Sanja Vickovic, Shanshan Yin, Shoukai Kang, Sonja Suvakov, Sundeep Khosla, Vesna D Garovic, Vilas Menon, Yanxin Xu, Yizhe Song, Yousin Suh, Zhixun Dou, Nicola Neretti
SenNet recommendations for detecting senescent cells in different tissues. Nature reviews. Molecular cell biology (2024)
Stella Victorelli, Hanna Salmonowicz, James Chapman, Helene Martini, Maria Grazia Vizioli, Joel S Riley, Catherine Cloix, Ella Hall-Younger, Jair Machado Espindola-Netto, Diana Jurk, Anthony B Lagnado, Lilian Sales Gomez, Joshua N Farr, Dominik Saul, Rebecca Reed, George Kelly, Madeline Eppard, Laura C Greaves, Zhixun Dou, Nicholas Pirius, Karolina Szczepanowska, Rebecca A Porritt, Huijie Huang, Timothy Y Huang, Derek A Mann, Claudio Akio Masuda, Sundeep Khosla, Haiming Dai, Scott H Kaufmann, Emmanouil Zacharioudakis, Evripidis Gavathiotis, Nathan K LeBrasseur, Xue Lei, Alva G Sainz, Viktor I Korolchuk, Peter D Adams, Gerald S Shadel, Stephen W G Tait, João F Passos
Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature (2024)
Joshua N Farr, Elizabeth J Atkinson, Sara J Achenbach, Tammie L Volkman, Amanda J Tweed, Stephanie J Vos, Ming Ruan, Jad G Sfeir, Matthew T Drake, Dominik Saul, Madison L Doolittle, Irina Bancos, Kai Yu, Tamara Tchkonia, Nathan K LeBrasseur, James L Kirkland, David G Monroe, Sundeep Khosla
Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial. Nature medicine (2024)
Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Amit Kumar Dey, Ann Hertzel, Anthony Agudelo, Azucena Rocha, Bikem Soygur, Birgit Schilling, Chase M Carver, Cristina Aguayo-Mazzucato, Darren J Baker, David A Bernlohr, Diana Jurk, Dilyana B Mangarova, Ellen M Quardokus, Elizabeth Ann L Enninga, Elizabeth L Schmidt, Feng Chen, Francesca E Duncan, Francesco Cambuli, Gagandeep Kaur, George A Kuchel, Gung Lee, Heike E Daldrup-Link, Helene Martini, Hemali Phatnani, Iman M Al-Naggar, Irfan Rahman, Jia Nie, João F Passos, Jonathan C Silverstein, Judith Campisi, Julia Wang, Kanako Iwasaki, Karina Barbosa, Kay Metis, Kerem Nernekli, Laura J Niedernhofer, Li Ding, Lichao Wang, Lisa C Adams, Liu Ruiyang, Madison L Doolittle, Marcos G Teneche, Marissa J Schafer, Ming Xu, Mohammadjavad Hajipour, Mozhgan Boroumand, Nathan Basisty, Nicholas Sloan, Nikolai Slavov, Olena Kuksenko, Paul Robson, Paul T Gomez, Periklis Vasilikos, Peter D Adams, Priscila Carapeto, Quan Zhu, Ramalakshmi Ramasamy, Rolando Perez-Lorenzo, Rong Fan, Runze Dong, Ruth Rebecca Montgomery, Sadiya Shaikh, Sanja Vickovic, Shanshan Yin, Shoukai Kang, Sonja Suvakov, Sundeep Khosla, Vesna D Garovic, Vilas Menon, Yanxin Xu, Yizhe Song, Yousin Suh, Zhixun Dou, Nicola Neretti
SenNet recommendations for detecting senescent cells in different tissues. Nature reviews. Molecular cell biology (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Amit Kumar Dey, Ann Hertzel, Anthony Agudelo, Azucena Rocha, Bikem Soygur, Birgit Schilling, Chase M Carver, Cristina Aguayo-Mazzucato, Darren J Baker, David A Bernlohr, Diana Jurk, Dilyana B Mangarova, Ellen M Quardokus, Elizabeth Ann L Enninga, Elizabeth L Schmidt, Feng Chen, Francesca E Duncan, Francesco Cambuli, Gagandeep Kaur, George A Kuchel, Gung Lee, Heike E Daldrup-Link, Helene Martini, Hemali Phatnani, Iman M Al-Naggar, Irfan Rahman, Jia Nie, João F Passos, Jonathan C Silverstein, Judith Campisi, Julia Wang, Kanako Iwasaki, Karina Barbosa, Kay Metis, Kerem Nernekli, Laura J Niedernhofer, Li Ding, Lichao Wang, Lisa C Adams, Liu Ruiyang, Madison L Doolittle, Marcos G Teneche, Marissa J Schafer, Ming Xu, Mohammadjavad Hajipour, Mozhgan Boroumand, Nathan Basisty, Nicholas Sloan, Nikolai Slavov, Olena Kuksenko, Paul Robson, Paul T Gomez, Periklis Vasilikos, Peter D Adams, Priscila Carapeto, Quan Zhu, Ramalakshmi Ramasamy, Rolando Perez-Lorenzo, Rong Fan, Runze Dong, Ruth Rebecca Montgomery, Sadiya Shaikh, Sanja Vickovic, Shanshan Yin, Shoukai Kang, Sonja Suvakov, Sundeep Khosla, Vesna D Garovic, Vilas Menon, Yanxin Xu, Yizhe Song, Yousin Suh, Zhixun Dou, Nicola Neretti
SenNet recommendations for detecting senescent cells in different tissues. Nature reviews. Molecular cell biology (2024)
Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Amit Kumar Dey, Ann Hertzel, Anthony Agudelo, Azucena Rocha, Bikem Soygur, Birgit Schilling, Chase M Carver, Cristina Aguayo-Mazzucato, Darren J Baker, David A Bernlohr, Diana Jurk, Dilyana B Mangarova, Ellen M Quardokus, Elizabeth Ann L Enninga, Elizabeth L Schmidt, Feng Chen, Francesca E Duncan, Francesco Cambuli, Gagandeep Kaur, George A Kuchel, Gung Lee, Heike E Daldrup-Link, Helene Martini, Hemali Phatnani, Iman M Al-Naggar, Irfan Rahman, Jia Nie, João F Passos, Jonathan C Silverstein, Judith Campisi, Julia Wang, Kanako Iwasaki, Karina Barbosa, Kay Metis, Kerem Nernekli, Laura J Niedernhofer, Li Ding, Lichao Wang, Lisa C Adams, Liu Ruiyang, Madison L Doolittle, Marcos G Teneche, Marissa J Schafer, Ming Xu, Mohammadjavad Hajipour, Mozhgan Boroumand, Nathan Basisty, Nicholas Sloan, Nikolai Slavov, Olena Kuksenko, Paul Robson, Paul T Gomez, Periklis Vasilikos, Peter D Adams, Priscila Carapeto, Quan Zhu, Ramalakshmi Ramasamy, Rolando Perez-Lorenzo, Rong Fan, Runze Dong, Ruth Rebecca Montgomery, Sadiya Shaikh, Sanja Vickovic, Shanshan Yin, Shoukai Kang, Sonja Suvakov, Sundeep Khosla, Vesna D Garovic, Vilas Menon, Yanxin Xu, Yizhe Song, Yousin Suh, Zhixun Dou, Nicola Neretti
SenNet recommendations for detecting senescent cells in different tissues. Nature reviews. Molecular cell biology (2024)
Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Amit Kumar Dey, Ann Hertzel, Anthony Agudelo, Azucena Rocha, Bikem Soygur, Birgit Schilling, Chase M Carver, Cristina Aguayo-Mazzucato, Darren J Baker, David A Bernlohr, Diana Jurk, Dilyana B Mangarova, Ellen M Quardokus, Elizabeth Ann L Enninga, Elizabeth L Schmidt, Feng Chen, Francesca E Duncan, Francesco Cambuli, Gagandeep Kaur, George A Kuchel, Gung Lee, Heike E Daldrup-Link, Helene Martini, Hemali Phatnani, Iman M Al-Naggar, Irfan Rahman, Jia Nie, João F Passos, Jonathan C Silverstein, Judith Campisi, Julia Wang, Kanako Iwasaki, Karina Barbosa, Kay Metis, Kerem Nernekli, Laura J Niedernhofer, Li Ding, Lichao Wang, Lisa C Adams, Liu Ruiyang, Madison L Doolittle, Marcos G Teneche, Marissa J Schafer, Ming Xu, Mohammadjavad Hajipour, Mozhgan Boroumand, Nathan Basisty, Nicholas Sloan, Nikolai Slavov, Olena Kuksenko, Paul Robson, Paul T Gomez, Periklis Vasilikos, Peter D Adams, Priscila Carapeto, Quan Zhu, Ramalakshmi Ramasamy, Rolando Perez-Lorenzo, Rong Fan, Runze Dong, Ruth Rebecca Montgomery, Sadiya Shaikh, Sanja Vickovic, Shanshan Yin, Shoukai Kang, Sonja Suvakov, Sundeep Khosla, Vesna D Garovic, Vilas Menon, Yanxin Xu, Yizhe Song, Yousin Suh, Zhixun Dou, Nicola Neretti
SenNet recommendations for detecting senescent cells in different tissues. Nature reviews. Molecular cell biology (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Amit Kumar Dey, Ann Hertzel, Anthony Agudelo, Azucena Rocha, Bikem Soygur, Birgit Schilling, Chase M Carver, Cristina Aguayo-Mazzucato, Darren J Baker, David A Bernlohr, Diana Jurk, Dilyana B Mangarova, Ellen M Quardokus, Elizabeth Ann L Enninga, Elizabeth L Schmidt, Feng Chen, Francesca E Duncan, Francesco Cambuli, Gagandeep Kaur, George A Kuchel, Gung Lee, Heike E Daldrup-Link, Helene Martini, Hemali Phatnani, Iman M Al-Naggar, Irfan Rahman, Jia Nie, João F Passos, Jonathan C Silverstein, Judith Campisi, Julia Wang, Kanako Iwasaki, Karina Barbosa, Kay Metis, Kerem Nernekli, Laura J Niedernhofer, Li Ding, Lichao Wang, Lisa C Adams, Liu Ruiyang, Madison L Doolittle, Marcos G Teneche, Marissa J Schafer, Ming Xu, Mohammadjavad Hajipour, Mozhgan Boroumand, Nathan Basisty, Nicholas Sloan, Nikolai Slavov, Olena Kuksenko, Paul Robson, Paul T Gomez, Periklis Vasilikos, Peter D Adams, Priscila Carapeto, Quan Zhu, Ramalakshmi Ramasamy, Rolando Perez-Lorenzo, Rong Fan, Runze Dong, Ruth Rebecca Montgomery, Sadiya Shaikh, Sanja Vickovic, Shanshan Yin, Shoukai Kang, Sonja Suvakov, Sundeep Khosla, Vesna D Garovic, Vilas Menon, Yanxin Xu, Yizhe Song, Yousin Suh, Zhixun Dou, Nicola Neretti
SenNet recommendations for detecting senescent cells in different tissues. Nature reviews. Molecular cell biology (2024)
Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Amit Kumar Dey, Ann Hertzel, Anthony Agudelo, Azucena Rocha, Bikem Soygur, Birgit Schilling, Chase M Carver, Cristina Aguayo-Mazzucato, Darren J Baker, David A Bernlohr, Diana Jurk, Dilyana B Mangarova, Ellen M Quardokus, Elizabeth Ann L Enninga, Elizabeth L Schmidt, Feng Chen, Francesca E Duncan, Francesco Cambuli, Gagandeep Kaur, George A Kuchel, Gung Lee, Heike E Daldrup-Link, Helene Martini, Hemali Phatnani, Iman M Al-Naggar, Irfan Rahman, Jia Nie, João F Passos, Jonathan C Silverstein, Judith Campisi, Julia Wang, Kanako Iwasaki, Karina Barbosa, Kay Metis, Kerem Nernekli, Laura J Niedernhofer, Li Ding, Lichao Wang, Lisa C Adams, Liu Ruiyang, Madison L Doolittle, Marcos G Teneche, Marissa J Schafer, Ming Xu, Mohammadjavad Hajipour, Mozhgan Boroumand, Nathan Basisty, Nicholas Sloan, Nikolai Slavov, Olena Kuksenko, Paul Robson, Paul T Gomez, Periklis Vasilikos, Peter D Adams, Priscila Carapeto, Quan Zhu, Ramalakshmi Ramasamy, Rolando Perez-Lorenzo, Rong Fan, Runze Dong, Ruth Rebecca Montgomery, Sadiya Shaikh, Sanja Vickovic, Shanshan Yin, Shoukai Kang, Sonja Suvakov, Sundeep Khosla, Vesna D Garovic, Vilas Menon, Yanxin Xu, Yizhe Song, Yousin Suh, Zhixun Dou, Nicola Neretti
SenNet recommendations for detecting senescent cells in different tissues. Nature reviews. Molecular cell biology (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Dominik Saul, Madison L Doolittle, Jennifer L Rowsey, Mitchell N Froemming, Robyn Laura Kosinsky, Stephanie J Vos, Ming Ruan, Nathan K LeBrasseur, Abhishek Chandra, Robert J Pignolo, João F Passos, Joshua N Farr, David G Monroe, Sundeep Khosla
Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair. bioRxiv : the preprint server for biology (2024)
Vidyani Suryadevara, Adam D Hudgins, Adarsh Rajesh, Alberto Pappalardo, Alla Karpova, Amit Kumar Dey, Ann Hertzel, Anthony Agudelo, Azucena Rocha, Bikem Soygur, Birgit Schilling, Chase M Carver, Cristina Aguayo-Mazzucato, Darren J Baker, David A Bernlohr, Diana Jurk, Dilyana B Mangarova, Ellen M Quardokus, Elizabeth Ann L Enninga, Elizabeth L Schmidt, Feng Chen, Francesca E Duncan, Francesco Cambuli, Gagandeep Kaur, George A Kuchel, Gung Lee, Heike E Daldrup-Link, Helene Martini, Hemali Phatnani, Iman M Al-Naggar, Irfan Rahman, Jia Nie, João F Passos, Jonathan C Silverstein, Judith Campisi, Julia Wang, Kanako Iwasaki, Karina Barbosa, Kay Metis, Kerem Nernekli, Laura J Niedernhofer, Li Ding, Lichao Wang, Lisa C Adams, Liu Ruiyang, Madison L Doolittle, Marcos G Teneche, Marissa J Schafer, Ming Xu, Mohammadjavad Hajipour, Mozhgan Boroumand, Nathan Basisty, Nicholas Sloan, Nikolai Slavov, Olena Kuksenko, Paul Robson, Paul T Gomez, Periklis Vasilikos, Peter D Adams, Priscila Carapeto, Quan Zhu, Ramalakshmi Ramasamy, Rolando Perez-Lorenzo, Rong Fan, Runze Dong, Ruth Rebecca Montgomery, Sadiya Shaikh, Sanja Vickovic, Shanshan Yin, Shoukai Kang, Sonja Suvakov, Sundeep Khosla, Vesna D Garovic, Vilas Menon, Yanxin Xu, Yizhe Song, Yousin Suh, Zhixun Dou, Nicola Neretti
SenNet recommendations for detecting senescent cells in different tissues. Nature reviews. Molecular cell biology (2024)
Xu Zhang, Yan Er Ng, Lucas C S Chini, Amanda A Heeren, Thomas A White, Hao Li, Haojie Huang, Madison L Doolittle, Sundeep Khosla, Nathan K LeBrasseur
Senescent skeletal muscle fibroadipogenic progenitors recruit and promote M2 polarization of macrophages. Aging cell (2023)
Dominik Saul, Diana Jurk, Madison L Doolittle, Robyn Laura Kosinsky, David G Monroe, Nathan K LeBrasseur, Paul D Robbins, Laura J Niedernhofer, Sundeep Khosla, João F Passos
Distinct secretomes in p16- and p21- positive senescent cells across tissues. bioRxiv : the preprint server for biology (2023)
Sundeep Khosla
Senescent cells, senolytics and tissue repair: the devil may be in the dosing. Nature aging 3 (2) (2023)
Xu Zhang, Yan Er Ng, Lucas C S Chini, Amanda A Heeren, Thomas A White, Hao Li, Haojie Huang, Madison L Doolittle, Sundeep Khosla, Nathan K LeBrasseur
Senescent skeletal muscle fibroadipogenic progenitors recruit and promote M2 polarization of macrophages. Aging cell 23 (3) (2023)
Xu Zhang, Yan Er Ng, Lucas C S Chini, Amanda A Heeren, Thomas A White, Hao Li, Haojie Huang, Madison L Doolittle, Sundeep Khosla, Nathan K LeBrasseur
Senescent skeletal muscle fibroadipogenic progenitors recruit and promote M2 polarization of macrophages. Aging cell (2023)
Stella Victorelli, Hanna Salmonowicz, James Chapman, Helene Martini, Maria Grazia Vizioli, Joel S Riley, Catherine Cloix, Ella Hall-Younger, Jair Machado Espindola-Netto, Diana Jurk, Anthony B Lagnado, Lilian Sales Gomez, Joshua N Farr, Dominik Saul, Rebecca Reed, George Kelly, Madeline Eppard, Laura C Greaves, Zhixun Dou, Nicholas Pirius, Karolina Szczepanowska, Rebecca A Porritt, Huijie Huang, Timothy Y Huang, Derek A Mann, Claudio Akio Masuda, Sundeep Khosla, Haiming Dai, Scott H Kaufmann, Emmanouil Zacharioudakis, Evripidis Gavathiotis, Nathan K LeBrasseur, Xue Lei, Alva G Sainz, Viktor I Korolchuk, Peter D Adams, Gerald S Shadel, Stephen W G Tait, João F Passos
Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature (2023)
Xu Zhang, Yan Er Ng, Lucas C S Chini, Amanda A Heeren, Thomas A White, Hao Li, Haojie Huang, Madison L Doolittle, Sundeep Khosla, Nathan K LeBrasseur
Senescent skeletal muscle fibroadipogenic progenitors recruit and promote M2 polarization of macrophages. Aging cell 23 (3) (2023)
Dominik Saul, Diana Jurk, Madison L Doolittle, Robyn Laura Kosinsky, David G Monroe, Nathan K LeBrasseur, Paul D Robbins, Laura J Niedernhofer, Sundeep Khosla, João F Passos
Distinct secretomes in p16- and p21- positive senescent cells across tissues. bioRxiv : the preprint server for biology (2023)
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Stephanie J Vos, Kevin D Pavelko, Joshua N Farr, David G Monroe, Sundeep Khosla
Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton. Nature communications 14 (1) (2023)
Dominik Saul, Diana Jurk, Madison L Doolittle, Robyn Laura Kosinsky, David G Monroe, Nathan K LeBrasseur, Paul D Robbins, Laura J Niedernhofer, Sundeep Khosla, João F Passos
Distinct secretomes in p16- and p21- positive senescent cells across tissues. bioRxiv : the preprint server for biology (2023)
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Stephanie J Vos, Kevin D Pavelko, Joshua N Farr, David G Monroe, Sundeep Khosla
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton. bioRxiv : the preprint server for biology (2023)
Stefan Bartenschlager, Alexander Cavallaro, Tobias Pogarell, Oliver Chaudry, Michael Uder, Sundeep Khosla, Larissa Valor-Méndez, Klaus Engelke
Opportunistic screening with CT: comparison of phantomless BMD calibration methods. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research (2023)
Xu Zhang, Yan Er Ng, Lucas C S Chini, Amanda A Heeren, Thomas A White, Hao Li, Haojie Huang, Madison L Doolittle, Sundeep Khosla, Nathan K LeBrasseur
Senescent skeletal muscle fibroadipogenic progenitors recruit and promote M2 polarization of macrophages. Aging cell 23 (3) (2023)
Xu Zhang, Yan Er Ng, Lucas C S Chini, Amanda A Heeren, Thomas A White, Hao Li, Haojie Huang, Madison L Doolittle, Sundeep Khosla, Nathan K LeBrasseur
Senescent skeletal muscle fibroadipogenic progenitors recruit and promote M2 polarization of macrophages. Aging cell 23 (3) (2023)
Sundeep Khosla
Senescent cells, senolytics and tissue repair: the devil may be in the dosing. Nature aging 3 (2) (2023)
Sundeep Khosla
Senescent cells, senolytics and tissue repair: the devil may be in the dosing. Nature aging 3 (2) (2023)
Madison L Doolittle, Brittany A Eckhardt, Stephanie J Vos, Sarah Grain, Jennifer L Rowsey, Ming Ruan, Dominik Saul, Joshua N Farr, Megan M Weivoda, Sundeep Khosla, David G Monroe
Modest Effects of Osteoclast-Specific ERα Deletion after Skeletal Maturity. JBMR plus 7 (10) (2023)
Danielle E Whittier, Elizabeth J Samelson, Marian T Hannan, Lauren A Burt, David A Hanley, Emmanuel Biver, Pawel Szulc, Elisabeth Sornay-Rendu, Blandine Merle, Roland D Chapurlat, Eric Lespessailles, Andy Kin On Wong, David Goltzman, Sundeep Khosla, Serge Livio Ferrari, Mary L Bouxsein, Douglas P Kiel, Steven K Boyd
A Fracture Risk Assessment Tool for High Resolution Peripheral Quantitative Computed Tomography. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research (2023)
Japneet Kaur, Dominik Saul, Madison L Doolittle, Joshua N Farr, Sundeep Khosla, David G Monroe
MicroRNA - 19a - 3p Decreases with Age in Mice and Humans and Inhibits Osteoblast Senescence. JBMR plus 7 (6) (2023)
Dominik Saul, Diana Jurk, Madison L Doolittle, Robyn Laura Kosinsky, David G Monroe, Nathan K LeBrasseur, Paul D Robbins, Laura J Niedernhofer, Sundeep Khosla, João F Passos
Distinct secretomes in p16- and p21- positive senescent cells across tissues. bioRxiv : the preprint server for biology (2023)
Madison L Doolittle, Sundeep Khosla, Dominik Saul
Single-Cell Integration of BMD GWAS Results Prioritize Candidate Genes Influencing Age-Related Bone Loss. JBMR plus 7 (10) (2023)
Zaira Aversa, Thomas A White, Amanda A Heeren, Cassondra A Hulshizer, Dominik Saul, Xu Zhang, Anthony J A Molina, Leanne M Redman, Corby K Martin, Susan B Racette, Kim M Huffman, Manjushri Bhapkar, Sundeep Khosla, Sai Krupa Das, Roger A Fielding, Elizabeth J Atkinson, Nathan K LeBrasseur
Calorie restriction reduces biomarkers of cellular senescence in humans. Aging cell (2023)
Sara E Espinoza, Sundeep Khosla, Joseph A Baur, Rafael de Cabo, Nicolas Musi
Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop. The journals of gerontology. Series A, Biological sciences and medical sciences 78 (Supplement_1) (2023)
Dominik Saul, Diana Jurk, Madison L Doolittle, Robyn Laura Kosinsky, David G Monroe, Nathan K LeBrasseur, Paul D Robbins, Laura J Niedernhofer, Sundeep Khosla, João F Passos
Distinct secretomes in p16- and p21- positive senescent cells across tissues. bioRxiv : the preprint server for biology (2023)
Parinya Samakkarnthai, Dominik Saul, Lei Zhang, Zaira Aversa, Madison L Doolittle, Jad G Sfeir, Japneet Kaur, Elizabeth J Atkinson, James R Edwards, R Graham G Russell, Robert J Pignolo, James L Kirkland, Tamara Tchkonia, Laura J Niedernhofer, David G Monroe, Nathan K LeBrasseur, Joshua N Farr, Paul D Robbins, Sundeep Khosla
In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers. bioRxiv : the preprint server for biology (2023)
Sundeep Khosla
Senescent cells, senolytics and tissue repair: the devil may be in the dosing. Nature aging 3 (2) (2023)
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Stephanie J Vos, Kevin D Pavelko, Joshua N Farr, David G Monroe, Sundeep Khosla
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton. bioRxiv : the preprint server for biology (2023)
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Stephanie J Vos, Kevin D Pavelko, Joshua N Farr, David G Monroe, Sundeep Khosla
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton. bioRxiv : the preprint server for biology (2023)
Danielle E Whittier, Elizabeth J Samelson, Marian T Hannan, Lauren A Burt, David A Hanley, Emmanuel Biver, Pawel Szulc, Elisabeth Sornay-Rendu, Blandine Merle, Roland D Chapurlat, Eric Lespessailles, Andy Kin On Wong, David Goltzman, Sundeep Khosla, Serge Livio Ferrari, Mary L Bouxsein, Douglas P Kiel, Steven K Boyd
Bone Microarchitecture Phenotypes Identified in Older Adults Are Associated With Different Levels of Osteoporotic Fracture Risk. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 37 (3) (2022)
Madison L Doolittle, Dominik Saul, Japneet Kaur, Jennifer L Rowsey, Brittany Eckhardt, Stephanie Vos, Sarah Grain, Kveta Kroupova, Ming Ruan, Megan Weivoda, Merry Jo Oursler, Joshua N Farr, David G Monroe, Sundeep Khosla
Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 37 (9) (2022)
Dominik Saul, Robyn Laura Kosinsky, Elizabeth J Atkinson, Madison L Doolittle, Xu Zhang, Nathan K LeBrasseur, Robert J Pignolo, Paul D Robbins, Laura J Niedernhofer, Yuji Ikeno, Diana Jurk, João F Passos, LaTonya J Hickson, Ailing Xue, David G Monroe, Tamara Tchkonia, James L Kirkland, Joshua N Farr, Sundeep Khosla
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues. Nature communications 13 (1) (2022)
Abhishek Chandra, Anthony B Lagnado, Joshua N Farr, Madison Doolittle, Tamara Tchkonia, James L Kirkland, Nathan K LeBrasseur, Paul D Robbins, Laura J Niedernhofer, Yuji Ikeno, João F Passos, David G Monroe, Robert J Pignolo, Sundeep Khosla
Targeted clearance of p21- but not p16-positive senescent cells prevents radiation-induced osteoporosis and increased marrow adiposity. Aging cell 21 (5) (2022)
Dominik Saul, Sundeep Khosla
Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence. Endocrine reviews 43 (6) (2022)
Abhishek Chandra, Anthony B Lagnado, Joshua N Farr, Megan Schleusner, David G Monroe, Dominik Saul, João F Passos, Sundeep Khosla, Robert J Pignolo
Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescence. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 37 (5) (2022)
Richard Eastell, Eric Vittinghoff, Li-Yung Lui, Charles E McCulloch, Imre Pavo, Arkadi Chines, Sundeep Khosla, Jane A Cauley, Bruce H Mitlak, Douglas C Bauer, Mary L Bouxsein, Dennis M Black
Validation of the Surrogate Threshold Effect for Change in Bone Mineral Density as a Surrogate Endpoint for Fracture Outcomes: The FNIH-ASBMR SABRE Project. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research (2021)
Ruben Aquino-Martinez, Brittany A Eckhardt, Jennifer L Rowsey, Daniel G Fraser, Sundeep Khosla, Joshua N Farr, David G Monroe
Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice. Journal of periodontology 92 (10) (2021)
Sundeep Khosla, Parinya Samakkarnthai, David G Monroe, Joshua N Farr
Update on the pathogenesis and treatment of skeletal fragility in type 2 diabetes mellitus. Nature reviews. Endocrinology 17 (11) (2021)
Dominik Saul, David G Monroe, Jennifer L Rowsey, Robyn Laura Kosinsky, Stephanie J Vos, Madison L Doolittle, Joshua N Farr, Sundeep Khosla
Modulation of fracture healing by the transient accumulation of senescent cells. eLife 10 (2021)
Christina D Camell, Matthew J Yousefzadeh, Yi Zhu, Larissa G P Langhi Prata, Matthew A Huggins, Mark Pierson, Lei Zhang, Ryan D O'Kelly, Tamar Pirtskhalava, Peng Cheng Xun, Keisuke Ejima, Ailing Xue, Utkarsh Tripathi, Jair Machado Espindola-Netto, Nino Giorgadze, Elizabeth J Atkinson, Christina L Inman, Kurt O Johnson, Stephanie H Cholensky, Timothy W Carlson, Nathan K LeBrasseur, Sundeep Khosla, M Gerard O'Sullivan, David B Allison, Stephen C Jameson, Alexander Meves, Ming Li, Y S Prakash, Sergio E Chiarella, Sara E Hamilton, Tamara Tchkonia, Laura J Niedernhofer, James L Kirkland, Paul D Robbins
Senolytics reduce coronavirus-related mortality in old mice. Science (New York, N.Y.) 373 (6552) (2021)
Megan M Weivoda, Chee Kian Chew, David G Monroe, Joshua N Farr, Elizabeth J Atkinson, Jennifer R Geske, Brittany Eckhardt, Brianne Thicke, Ming Ruan, Amanda J Tweed, Louise K McCready, Robert A Rizza, Aleksey Matveyenko, Moustapha Kassem, Thomas Levin Andersen, Adrian Vella, Matthew T Drake, Bart L Clarke, Merry Jo Oursler, Sundeep Khosla
Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism. Nature communications 11 (1) (2020)
Namki Hong, David C Lee, Sundeep Khosla, Tony M Keaveny, Yumie Rhee
Comparison of Vertebral and Femoral Strength Between White and Asian Adults Using Finite Element Analysis of Computed Tomography Scans. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 35 (12) (2020)
Abhishek Chandra, Anthony B Lagnado, Joshua N Farr, David G Monroe, Sean Park, Christine Hachfeld, Tamar Tchkonia, James L Kirkland, Sundeep Khosla, João F Passos, Robert J Pignolo
Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 35 (6) (2020)
Sundeep Khosla, Joshua N Farr, Tamara Tchkonia, James L Kirkland
The role of cellular senescence in ageing and endocrine disease. Nature reviews. Endocrinology 16 (5) (2020)
Nicola Napoli, Ann L Elderkin, Douglas P Kiel, Sundeep Khosla
Managing fragility fractures during the COVID-19 pandemic. Nature reviews. Endocrinology 16 (9) (2020)
Richard Eastell, Dennis M Black, Li-Yung Lui, Arkadi Chines, Fernando Marin, Sundeep Khosla, Anne E de Papp, Jane A Cauley, Bruce Mitlak, Charles E McCulloch, Eric Vittinghoff, Douglas C Bauer, null null
Treatment-Related Changes in Bone Turnover and Fracture Risk Reduction in Clinical Trials of Antiresorptive Drugs: Proportion of Treatment Effect Explained. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 36 (2) (2020)
Benjamin Z Leder, Bart L Clarke, Elizabeth Shane, Sundeep Khosla, Douglas P Kiel
A Lot of Progress, With More to Be Done: A Response to NIH Pathways to Prevention Report "Research Gaps for Long-Term Drug Therapies for Osteoporotic Fracture Prevention". Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 34 (9) (2019)
Robert B Conley, Gemma Adib, Robert A Adler, Kristina E Åkesson, Ivy M Alexander, Kelly C Amenta, Robert D Blank, William Timothy Brox, Emily E Carmody, Karen Chapman-Novakofski, Bart Lyman Clarke, Kathleen M Cody, Cyrus Cooper, Carolyn J Crandall, Douglas R Dirschl, Thomas J Eagen, Ann L Elderkin, Masaki Fujita, Susan L Greenspan, Philippe Halbout, Marc C Hochberg, Muhammad Javaid, Kyle J Jeray, Ann E Kearns, Toby King, Thomas F Koinis, Jennifer Scott Koontz, Martin Kužma, Carleen Lindsey, Mattias Lorentzon, George P Lyritis, Laura Boehnke Michaud, Armando Miciano, Suzanne N Morin, Nadia Mujahid, Nicola Napoli, Thomas P Olenginski, J Edward Puzas, Stavroula Rizou, Clifford J Rosen, Kenneth Saag, Elizabeth Thompson, Laura L Tosi, Howard Tracer, Sundeep Khosla, Douglas P Kiel
Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 35 (1) (2019)
Joshua N Farr, Jennifer L Rowsey, Brittany A Eckhardt, Brianne S Thicke, Daniel G Fraser, Tamar Tchkonia, James L Kirkland, David G Monroe, Sundeep Khosla
Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 34 (8) (2019)
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser, Jennifer L Onken, Kurt O Johnson, Grace C Verzosa, Larissa G P Langhi, Moritz Weigl, Nino Giorgadze, Nathan K LeBrasseur, Jordan D Miller, Diana Jurk, Ravinder J Singh, David B Allison, Keisuke Ejima, Gene B Hubbard, Yuji Ikeno, Hajrunisa Cubro, Vesna D Garovic, Xiaonan Hou, S John Weroha, Paul D Robbins, Laura J Niedernhofer, Sundeep Khosla, Tamara Tchkonia, James L Kirkland
Senolytics improve physical function and increase lifespan in old age. Nature medicine 24 (8) (2018)
Joshua N Farr, Ming Xu, Megan M Weivoda, David G Monroe, Daniel G Fraser, Jennifer L Onken, Brittany A Negley, Jad G Sfeir, Mikolaj B Ogrodnik, Christine M Hachfeld, Nathan K LeBrasseur, Matthew T Drake, Robert J Pignolo, Tamar Pirtskhalava, Tamara Tchkonia, Merry Jo Oursler, James L Kirkland, Sundeep Khosla
Targeting cellular senescence prevents age-related bone loss in mice. Nature medicine 23 (9) (2017)