Kathleen A Farley

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 22

Top Venues

Journal of medicinal chemistry

Nature structural & molecular biology

ACS medicinal chemistry letters

Nature communications

Pfizer Global Research and Development

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Pfizer Global Research and Development Apr 01 2003 - Aug 01 2007

United States

Principal Scientist

Publications

Stephen W Wright, Kathleen A Farley, Seungil Han, John D Knafels, Katherine L Lee
In Retrospect: Root-Cause Analysis of Structure-Activity Relationships in IRAK4 Inhibitor Zimlovisertib (PF-06650833). ACS medicinal chemistry letters 15 (4) (2024)
Stephen W Wright, Kathleen A Farley, Seungil Han, John D Knafels, Katherine L Lee
In Retrospect: Root-Cause Analysis of Structure-Activity Relationships in IRAK4 Inhibitor Zimlovisertib (PF-06650833). ACS medicinal chemistry letters 15 (4) (2024)
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M Buzon, Rhonda D Cardin, Natasha R Catlin, Anthony A Carlo, Karen J Coffman, Alyssa Dantonio, Li Di, Heather Eng, Kathleen A Farley, Rose Ann Ferre, Steven S Gernhardt, Scott A Gibson, Samantha E Greasley, Siennah R Greenfield, Brett L Hurst, Amit S Kalgutkar, Emi Kimito, Lorraine F Lanyon, Gabrielle H Lovett, Yajing Lian, Wei Liu, Luis A Martínez Alsina, Stephen Noell, R Scott Obach, Dafydd R Owen, Nandini C Patel, Devendra K Rai, Matthew R Reese, Hussin A Rothan, Sylvie Sakata, Matthew F Sammons, Jean G Sathish, Raman Sharma, Claire M Steppan, Jamison B Tuttle, Patrick R Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. Journal of medicinal chemistry (2024)
David Jonathan Wasilko, Brian S Gerstenberger, Kathleen A Farley, Wei Li, Jennifer Alley, Mark E Schnute, Ray J Unwalla, Jorge Victorino, Kimberly K Crouse, Ru Ding, Parag V Sahasrabudhe, Fabien Vincent, Richard K Frisbie, Alpay Dermenci, Andrew C Flick, Chulho Choi, Gary Chinigo, James J Mousseau, John I Trujillo, Philippe Nuhant, Prolay Mondal, Vincent Lombardo, Daniel Lamb, Barbara J Hogan, Gurdeep Singh Minhas, Elena Segala, Christine Oswald, Ian W Windsor, Seungil Han, Mathieu Rappas, Robert M Cooke, Matthew F Calabrese, Gabriel Berstein, Atli Thorarensen, Huixian Wu
Structural basis for CCR6 modulation by allosteric antagonists. Nature communications 15 (1) (2024)
Justin Bellenger, Martin R M Koos, Melissa Avery, Mark Bundesmann, Gregory Ciszewski, Bhagyashree Khunte, Carolyn Leverett, Gregory Ostner, Tim F Ryder, Kathleen A Farley
An Automated Purification Workflow Coupled with Material-Sparing High-Throughput 1 H NMR for Parallel Medicinal Chemistry. ACS medicinal chemistry letters 15 (9) (2024)
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M Buzon, Rhonda D Cardin, Natasha R Catlin, Anthony A Carlo, Karen J Coffman, Alyssa Dantonio, Li Di, Heather Eng, Kathleen A Farley, Rose Ann Ferre, Steven S Gernhardt, Scott A Gibson, Samantha E Greasley, Siennah R Greenfield, Brett L Hurst, Amit S Kalgutkar, Emi Kimito, Lorraine F Lanyon, Gabrielle H Lovett, Yajing Lian, Wei Liu, Luis A Martínez Alsina, Stephen Noell, R Scott Obach, Dafydd R Owen, Nandini C Patel, Devendra K Rai, Matthew R Reese, Hussin A Rothan, Sylvie Sakata, Matthew F Sammons, Jean G Sathish, Raman Sharma, Claire M Steppan, Jamison B Tuttle, Patrick R Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. Journal of medicinal chemistry 67 (16) (2024)
David Jonathan Wasilko, Brian S Gerstenberger, Kathleen A Farley, Wei Li, Jennifer Alley, Mark E Schnute, Ray J Unwalla, Jorge Victorino, Kimberly K Crouse, Ru Ding, Parag V Sahasrabudhe, Fabien Vincent, Richard K Frisbie, Alpay Dermenci, Andrew C Flick, Chulho Choi, Gary Chinigo, James J Mousseau, John I Trujillo, Philippe Nuhant, Prolay Mondal, Vincent Lombardo, Daniel Lamb, Barbara J Hogan, Gurdeep Singh Minhas, Elena Segala, Christine Oswald, Ian W Windsor, Seungil Han, Mathieu Rappas, Robert M Cooke, Matthew F Calabrese, Gabriel Berstein, Atli Thorarensen, Huixian Wu
Structural basis for CCR6 modulation by allosteric antagonists. Nature communications 15 (1) (2024)
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M Buzon, Rhonda D Cardin, Natasha R Catlin, Anthony A Carlo, Karen J Coffman, Alyssa Dantonio, Li Di, Heather Eng, Kathleen A Farley, Rose Ann Ferre, Steven S Gernhardt, Scott A Gibson, Samantha E Greasley, Siennah R Greenfield, Brett L Hurst, Amit S Kalgutkar, Emi Kimito, Lorraine F Lanyon, Gabrielle H Lovett, Yajing Lian, Wei Liu, Luis A Martínez Alsina, Stephen Noell, R Scott Obach, Dafydd R Owen, Nandini C Patel, Devendra K Rai, Matthew R Reese, Hussin A Rothan, Sylvie Sakata, Matthew F Sammons, Jean G Sathish, Raman Sharma, Claire M Steppan, Jamison B Tuttle, Patrick R Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. Journal of medicinal chemistry 67 (16) (2024)
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M Buzon, Rhonda D Cardin, Natasha R Catlin, Anthony A Carlo, Karen J Coffman, Alyssa Dantonio, Li Di, Heather Eng, Kathleen A Farley, Rose Ann Ferre, Steven S Gernhardt, Scott A Gibson, Samantha E Greasley, Siennah R Greenfield, Brett L Hurst, Amit S Kalgutkar, Emi Kimito, Lorraine F Lanyon, Gabrielle H Lovett, Yajing Lian, Wei Liu, Luis A Martínez Alsina, Stephen Noell, R Scott Obach, Dafydd R Owen, Nandini C Patel, Devendra K Rai, Matthew R Reese, Hussin A Rothan, Sylvie Sakata, Matthew F Sammons, Jean G Sathish, Raman Sharma, Claire M Steppan, Jamison B Tuttle, Patrick R Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. Journal of medicinal chemistry 67 (16) (2024)
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Mohammad Amin Behzadi, Britton Boras, Leanne M Buzon, Rhonda D Cardin, Natasha R Catlin, Anthony A Carlo, Karen J Coffman, Alyssa Dantonio, Li Di, Heather Eng, Kathleen A Farley, Rose Ann Ferre, Steven S Gernhardt, Scott A Gibson, Samantha E Greasley, Siennah R Greenfield, Brett L Hurst, Amit S Kalgutkar, Emi Kimito, Lorraine F Lanyon, Gabrielle H Lovett, Yajing Lian, Wei Liu, Luis A Martínez Alsina, Stephen Noell, R Scott Obach, Dafydd R Owen, Nandini C Patel, Devendra K Rai, Matthew R Reese, Hussin A Rothan, Sylvie Sakata, Matthew F Sammons, Jean G Sathish, Raman Sharma, Claire M Steppan, Jamison B Tuttle, Patrick R Verhoest, Liuqing Wei, Qingyi Yang, Irina Yurgelonis, Yuao Zhu
A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. Journal of medicinal chemistry (2024)
Michelle R Garnsey, Aaron C Smith, Jana Polivkova, Autumn L Arons, Guoyun Bai, Caroline A Blakemore, Markus Boehm, Leanne M Buzon, Sarah N Campion, Matthew Cerny, Shiao-Chi Chang, Karen Coffman, Kathleen A Farley, Kari R Fonseca, Kristen K Ford, Jeonifer Garren, Jimmy X Kong, Martin R M Koos, Daniel W Kung, Yajing Lian, Monica M Li, Qifang Li, Luis A Martinez-Alsina, Rebecca O'Connor, Kevin Ogilvie, Kiyoyuki Omoto, Brian Raymer, Matthew R Reese, Tim Ryder, Lacey Samp, Kimberly A Stevens, Daniel W Widlicka, Qingyi Yang, Kaicheng Zhu, Jean-Philippe Fortin, Matthew F Sammons
Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss. Journal of medicinal chemistry 66 (5) (2023)
Michelle R Garnsey, Aaron C Smith, Jana Polivkova, Autumn L Arons, Guoyun Bai, Caroline A Blakemore, Markus Boehm, Leanne M Buzon, Sarah N Campion, Matthew Cerny, Shiao-Chi Chang, Karen Coffman, Kathleen A Farley, Kari R Fonseca, Kristen K Ford, Jeonifer Garren, Jimmy X Kong, Martin R M Koos, Daniel W Kung, Yajing Lian, Monica M Li, Qifang Li, Luis A Martinez-Alsina, Rebecca O'Connor, Kevin Ogilvie, Kiyoyuki Omoto, Brian Raymer, Matthew R Reese, Tim Ryder, Lacey Samp, Kimberly A Stevens, Daniel W Widlicka, Qingyi Yang, Kaicheng Zhu, Jean-Philippe Fortin, Matthew F Sammons
Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss. Journal of medicinal chemistry 66 (5) (2023)
Michelle R Garnsey, Aaron C Smith, Jana Polivkova, Autumn L Arons, Guoyun Bai, Caroline A Blakemore, Markus Boehm, Leanne M Buzon, Sarah N Campion, Matthew Cerny, Shiao-Chi Chang, Karen Coffman, Kathleen A Farley, Kari R Fonseca, Kristen K Ford, Jeonifer Garren, Jimmy X Kong, Martin R M Koos, Daniel W Kung, Yajing Lian, Monica M Li, Qifang Li, Luis A Martinez-Alsina, Rebecca O'Connor, Kevin Ogilvie, Kiyoyuki Omoto, Brian Raymer, Matthew R Reese, Tim Ryder, Lacey Samp, Kimberly A Stevens, Daniel W Widlicka, Qingyi Yang, Kaicheng Zhu, Jean-Philippe Fortin, Matthew F Sammons
Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss. Journal of medicinal chemistry (2023)
Michelle R Garnsey, Aaron C Smith, Jana Polivkova, Autumn L Arons, Guoyun Bai, Caroline A Blakemore, Markus Boehm, Leanne M Buzon, Sarah N Campion, Matthew Cerny, Shiao-Chi Chang, Karen Coffman, Kathleen A Farley, Kari R Fonseca, Kristen K Ford, Jeonifer Garren, Jimmy X Kong, Martin R M Koos, Daniel W Kung, Yajing Lian, Monica M Li, Qifang Li, Luis A Martinez-Alsina, Rebecca O'Connor, Kevin Ogilvie, Kiyoyuki Omoto, Brian Raymer, Matthew R Reese, Tim Ryder, Lacey Samp, Kimberly A Stevens, Daniel W Widlicka, Qingyi Yang, Kaicheng Zhu, Jean-Philippe Fortin, Matthew F Sammons
Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss. Journal of medicinal chemistry 66 (5) (2023)
Zachary Lee Johnson, Mark Ammirati, David Jonathan Wasilko, Jeanne S Chang, Stephen Noell, Timothy L Foley, Hyejin Yoon, Kathleen Smith, Shoh Asano, Katherine Hales, Min Wan, Qingyi Yang, Mary A Piotrowski, Kathleen A Farley, Tamara Gilbert, Lisa M Aschenbrenner, Kimberly F Fennell, Jason K Dutra, Mary Xu, Chunyang Guo, Alison E Varghese, Justin Bellenger, Alandra Quinn, Christopher W Am Ende, Graham M West, Matthew C Griffor, Donald Bennett, Matthew F Calabrese, Claire M Steppan, Seungil Han, Huixian Wu
Structural basis of the acyl-transfer mechanism of human GPAT1. Nature structural & molecular biology 30 (1) (2022)
Zachary Lee Johnson, Mark Ammirati, David Jonathan Wasilko, Jeanne S Chang, Stephen Noell, Timothy L Foley, Hyejin Yoon, Kathleen Smith, Shoh Asano, Katherine Hales, Min Wan, Qingyi Yang, Mary A Piotrowski, Kathleen A Farley, Tamara Gilbert, Lisa M Aschenbrenner, Kimberly F Fennell, Jason K Dutra, Mary Xu, Chunyang Guo, Alison E Varghese, Justin Bellenger, Alandra Quinn, Christopher W Am Ende, Graham M West, Matthew C Griffor, Donald Bennett, Matthew F Calabrese, Claire M Steppan, Seungil Han, Huixian Wu
Structural basis of the acyl-transfer mechanism of human GPAT1. Nature structural & molecular biology 30 (1) (2022)
Zachary Lee Johnson, Mark Ammirati, David Jonathan Wasilko, Jeanne S Chang, Stephen Noell, Timothy L Foley, Hyejin Yoon, Kathleen Smith, Shoh Asano, Katherine Hales, Min Wan, Qingyi Yang, Mary A Piotrowski, Kathleen A Farley, Tamara Gilbert, Lisa M Aschenbrenner, Kimberly F Fennell, Jason K Dutra, Mary Xu, Chunyang Guo, Alison E Varghese, Justin Bellenger, Alandra Quinn, Christopher W Am Ende, Graham M West, Matthew C Griffor, Donald Bennett, Matthew F Calabrese, Claire M Steppan, Seungil Han, Huixian Wu
Structural basis of the acyl-transfer mechanism of human GPAT1. Nature structural & molecular biology 30 (1) (2022)
Zachary Lee Johnson, Mark Ammirati, David Jonathan Wasilko, Jeanne S Chang, Stephen Noell, Timothy L Foley, Hyejin Yoon, Kathleen Smith, Shoh Asano, Katherine Hales, Min Wan, Qingyi Yang, Mary A Piotrowski, Kathleen A Farley, Tamara Gilbert, Lisa M Aschenbrenner, Kimberly F Fennell, Jason K Dutra, Mary Xu, Chunyang Guo, Alison E Varghese, Justin Bellenger, Alandra Quinn, Christopher W Am Ende, Graham M West, Matthew C Griffor, Donald Bennett, Matthew F Calabrese, Claire M Steppan, Seungil Han, Huixian Wu
Structural basis of the acyl-transfer mechanism of human GPAT1. Nature structural & molecular biology 30 (1) (2022)
Zachary Lee Johnson, Mark Ammirati, David Jonathan Wasilko, Jeanne S Chang, Stephen Noell, Timothy L Foley, Hyejin Yoon, Kathleen Smith, Shoh Asano, Katherine Hales, Min Wan, Qingyi Yang, Mary A Piotrowski, Kathleen A Farley, Tamara Gilbert, Lisa M Aschenbrenner, Kimberly F Fennell, Jason K Dutra, Mary Xu, Chunyang Guo, Alison E Varghese, Justin Bellenger, Alandra Quinn, Christopher W Am Ende, Graham M West, Matthew C Griffor, Donald Bennett, Matthew F Calabrese, Claire M Steppan, Seungil Han, Huixian Wu
Structural basis of the acyl-transfer mechanism of human GPAT1. Nature structural & molecular biology (2022)
Agustin Casimiro-Garcia, Christophe Allais, Agnes Brennan, Chulho Choi, Gabriela Dower, Kathleen A Farley, Margaret Fleming, Andrew Flick, Richard K Frisbie, Justin Hall, David Hepworth, Hannah Jones, John D Knafels, Steve Kortum, Frank E Lovering, John P Mathias, Sashi Mohan, Paul M Morgan, Chuenlei Parng, Kevin Parris, Nick Pullen, Franklin Schlerman, John Stansfield, Joseph W Strohbach, Felix F Vajdos, Fabien Vincent, Hong Wang, Xiaolun Wang, Robert Webster, Stephen W Wright
Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1. Journal of medicinal chemistry 65 (1) (2021)
Kathleen A Farley, Martin R M Koos, Ye Che, Reto Horst, Chris Limberakis, Justin Bellenger, Ricardo Lira, Leandro F Gil-Silva, Roberto R Gil
Cross-Linked Poly-4-Acrylomorpholine: A Flexible and Reversibly Compressible Aligning Gel for Anisotropic NMR Analysis of Peptides and Small Molecules in Water. Angewandte Chemie (International ed. in English) 60 (50) (2021)
Kathleen A Farley, Ye Che, Armando Navarro-Vázquez, Chris Limberakis, Dennis Anderson, Jiangli Yan, Michael Shapiro, Veerabahu Shanmugasundaram, Roberto R Gil
Cyclic Peptide Design Guided by Residual Dipolar Couplings, J-Couplings, and Intramolecular Hydrogen Bond Analysis. The Journal of organic chemistry 84 (8) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Kathleen A Farley