Kyung S Lee (Kyung Lee)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 20

Top Venues

Nature communications

Journal of medicinal chemistry

ACS pharmacology & translational science

Cell cycle (Georgetown, Tex.)

National Cancer Institute/National Institutes of Health

Johns Hopkins University Bloomberg School of Public Health (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Cancer Institute/National Institutes of Health May 04 1998

United States

Senior Investigator :: Metabolism

Education History

Johns Hopkins University Bloomberg School of Public Health

United States

PHD :: Biochemistry

Publications

Jung-Eun Park, Tae-Sung Kim, Yan Zeng, Melissa Mikolaj, Jong Il Ahn, Muhammad S Alam, Christina M Monnie, Victoria Shi, Ming Zhou, Tae-Wook Chun, Frank Maldarelli, Kedar Narayan, Jinwoo Ahn, Jonathan D Ashwell, Klaus Strebel, Kyung S Lee
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4 + T cells. Nature communications 15 (1) (2024)
Jung-Eun Park, Tae-Sung Kim, Yan Zeng, Melissa Mikolaj, Jong Il Ahn, Muhammad S Alam, Christina M Monnie, Victoria Shi, Ming Zhou, Tae-Wook Chun, Frank Maldarelli, Kedar Narayan, Jinwoo Ahn, Jonathan D Ashwell, Klaus Strebel, Kyung S Lee
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4 + T cells. Nature communications 15 (1) (2024)
Jung-Eun Park, Tae-Sung Kim, Yan Zeng, Melissa Mikolaj, Jong Il Ahn, Muhammad S Alam, Christina M Monnie, Victoria Shi, Ming Zhou, Tae-Wook Chun, Frank Maldarelli, Kedar Narayan, Jinwoo Ahn, Jonathan D Ashwell, Klaus Strebel, Kyung S Lee
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4 + T cells. Nature communications 15 (1) (2024)
Jung-Eun Park, Tae-Sung Kim, Yan Zeng, Melissa Mikolaj, Jong Il Ahn, Muhammad S Alam, Christina M Monnie, Victoria Shi, Ming Zhou, Tae-Wook Chun, Frank Maldarelli, Kedar Narayan, Jinwoo Ahn, Jonathan D Ashwell, Klaus Strebel, Kyung S Lee
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4 + T cells. Nature communications 15 (1) (2024)
Jung-Eun Park, Tae-Sung Kim, Yan Zeng, Melissa Mikolaj, Jong Il Ahn, Muhammad S Alam, Christina M Monnie, Victoria Shi, Ming Zhou, Tae-Wook Chun, Frank Maldarelli, Kedar Narayan, Jinwoo Ahn, Jonathan D Ashwell, Klaus Strebel, Kyung S Lee
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4 + T cells. Nature communications 15 (1) (2024)
Kyung S Lee, Jung-Eun Park, Tae-Sung Kim, Yan Zeng, Christina Monnie, Muhammad Alam, Ming Zhou, Melissa Mikolaj, Frank Maldarelli, Kedar Narayan, Jinwoo Ahn, Jonathan D Ashwell, Klaus Strebel
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4+ T cells. Research square (2023)
Jong Il Ahn, Liang Zhang, Harsha Ravishankar, Lixin Fan, Klara Kirsch, Yan Zeng, Lingjun Meng, Jung-Eun Park, Hye-Yeoung Yun, Rodolfo Ghirlando, Buyong Ma, David Ball, Bonsu Ku, Ruth Nussinov, Jeremy D Schmit, William F Heinz, Seung Jun Kim, Tatiana S Karpova, Yun-Xing Wang, Kyung S Lee
Author Correction: Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells. Communications biology 6 (1) (2023)
Jung-Eun Park, Klara Kirsch, Hobin Lee, Paola Oliva, Jong Il Ahn, Harsha Ravishankar, Yan Zeng, Stephen D Fox, Samuel A Kirby, Pooja Badhwar, Thorkell Andresson, Kenneth A Jacobson, Kyung S Lee
Specific inhibition of an anticancer target, polo-like kinase 1, by allosterically dismantling its mechanism of substrate recognition. Proceedings of the National Academy of Sciences of the United States of America 120 (35) (2023)
Jung-Eun Park, Hobin Lee, Paola Oliva, Klara Kirsch, Bora Kim, Jong Il Ahn, Celeste N Alverez, Snehal Gaikwad, Kristopher W Krausz, Robert O'Connor, Ganesha Rai, Anton Simeonov, Beverly A Mock, Frank J Gonzalez, Kyung S Lee, Kenneth A Jacobson
Structural Optimization and Anticancer Activity of Polo-like Kinase 1 (Plk1) Polo-Box Domain (PBD) Inhibitors and Their Prodrugs. ACS pharmacology & translational science 6 (3) (2023)
Jong Il Ahn, Liang Zhang, Harsha Ravishankar, Lixin Fan, Klara Kirsch, Yan Zeng, Lingjun Meng, Jung-Eun Park, Hye-Yeoung Yun, Rodolfo Ghirlando, Buyong Ma, David Ball, Bonsu Ku, Ruth Nussinov, Jeremy D Schmit, William F Heinz, Seung Jun Kim, Tatiana S Karpova, Yun-Xing Wang, Kyung S Lee
Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells. Communications biology 6 (1) (2023)
Jung-Eun Park, Hobin Lee, Paola Oliva, Klara Kirsch, Bora Kim, Jong Il Ahn, Celeste N Alverez, Snehal Gaikwad, Kristopher W Krausz, Robert O'Connor, Ganesha Rai, Anton Simeonov, Beverly A Mock, Frank J Gonzalez, Kyung S Lee, Kenneth A Jacobson
Structural Optimization and Anticancer Activity of Polo-like Kinase 1 (Plk1) Polo-Box Domain (PBD) Inhibitors and Their Prodrugs. ACS pharmacology & translational science 6 (3) (2023)
SeongShick Ryu, Jung-Eun Park, Young Jin Ham, Daniel C Lim, Nicholas P Kwiatkowski, Do-Hee Kim, Debabrata Bhunia, Nam Doo Kim, Michael B Yaffe, Woolim Son, Namkyoung Kim, Tae-Ik Choi, Puspanjali Swain, Cheol-Hee Kim, Jin-Young Lee, Nathanael S Gray, Kyung S Lee, Taebo Sim
Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1. Journal of medicinal chemistry 65 (3) (2022)
Jong Il Ahn, Jung-Eun Park, Lingjun Meng, Liang Zhang, Tae-Sung Kim, Michael J Kruhlak, Bo Yeon Kim, Kyung S Lee
Phase separation of the Cep63•Cep152 complex underlies the formation of dynamic supramolecular self-assemblies at human centrosomes. Cell cycle (Georgetown, Tex.) 19 (24) (2020)
Celeste N Alverez, Jung-Eun Park, Kiran S Toti, Yangliu Xia, Kristopher W Krausz, Ganesha Rai, Jeong Kyu Bang, Frank J Gonzalez, Kenneth A Jacobson, Kyung S Lee
Identification of a New Heterocyclic Scaffold for Inhibitors of the Polo-Box Domain of Polo-like Kinase 1. Journal of medicinal chemistry 63 (22) (2020)
Zhuang Wei, Tae-Sung Kim, Jong Il Ahn, Lingjun Meng, Yaozong Chen, Eun Kyoung Ryu, Bonsu Ku, Ming Zhou, Seung Jun Kim, Jeong Kyu Bang, Jan M van Deursen, Jung-Eun Park, Kyung S Lee
Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication. Molecular and cellular biology 40 (10) (2020)
Jung-Eun Park, Lingjun Meng, Eun Kyoung Ryu, Kunio Nagashima, Ulrich Baxa, Jeong Kyu Bang, Kyung S Lee
Autophosphorylation-induced self-assembly and STIL-dependent reinforcement underlie Plk4's ring-to-dot localization conversion around a human centriole. Cell cycle (Georgetown, Tex.) 19 (24) (2020)
Pethaiah Gunasekaran, Min Su Yim, Mija Ahn, Nak-Kyun Soung, Jung-Eun Park, Jaehi Kim, Geul Bang, Sang Chul Shin, Joonhyeok Choi, Minkyoung Kim, Hak Nam Kim, Young-Ho Lee, Young-Ho Chung, Kyeong Lee, Eunice EunKyeong Kim, Young-Ho Jeon, Min Ju Kim, Kyeong-Ryoon Lee, Bo-Yeon Kim, Kyung S Lee, Eun Kyoung Ryu, Jeong Kyu Bang
Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models. Journal of medicinal chemistry 63 (23) (2020)
Jung-Eun Park, Liang Zhang, Jeong Kyu Bang, Thorkell Andresson, Frank DiMaio, Kyung S Lee
Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis. Nature communications 10 (1) (2019)
Tae-Sung Kim, Liang Zhang, Jong Il Ahn, Lingjun Meng, Yang Chen, Eunhye Lee, Jeong Kyu Bang, Jung Mi Lim, Rodolfo Ghirlando, Lixin Fan, Yun-Xing Wang, Bo Yeon Kim, Jung-Eun Park, Kyung S Lee
Molecular architecture of a cylindrical self-assembly at human centrosomes. Nature communications 10 (1) (2019)
Jung-Eun Park, David Hymel, Terrence R Burke, Kyung S Lee
Current progress and future perspectives in the development of anti-polo-like kinase 1 therapeutic agents. F1000Research 6 (2017)

Kyung S Lee.css-eqlu8i{font-size:small;padding-left:4px;} (Kyung Lee)

Publication Activity (10 Years)

Top Topics

Top Venues

Kyung S Lee (Kyung Lee)