Lars Plate

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 47

Top Venues

bioRxiv : the preprint server for biology

PloS one

eLife

The EMBO journal

Vanderbilt University

University of California Berkeley (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Vanderbilt University Aug 15 2017

United States

Assistant Professor :: Chemistry and Biological Sciences

Scripps Research Institute

United States

Postdoctoral Fellow :: Chemistry/Molecular and Experimental Medicine

Education History

University of California Berkeley

United States

PHD :: Molecular and Cell Biology

Massachusetts Institute of Technology

United States

BSC :: Chemistry

Publications

Eli Fritz McDonald, Minsoo Kim, John A Olson, Jens Meiler, Lars Plate
Proteostasis Landscapes of Selective versus Poorly Responsive CFTR Variants Reveals Structural Vulnerabilities to Correction. bioRxiv : the preprint server for biology (2024)
Jonathan P Davies, Lars Plate
The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis. bioRxiv : the preprint server for biology (2024)
Christian L Egly, Lea Barny, Tri Do, Eli Fritz McDonald, Lars Plate, Björn C Knollmann
The proteostasis interactomes of trafficking-deficient K V 11.1 variants associated with Long QT Syndrome and pharmacological chaperone rescue. bioRxiv : the preprint server for biology (2024)
Eli Fritz McDonald, Kathryn E Oliver, Jonathan P Schlebach, Jens Meiler, Lars Plate
Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants. PloS one 19 (1) (2024)
Madison T Wright, Bibek Timalsina, Valeria Garcia Lopez, Jake N Hermanson, Sarah Garcia, Lars Plate
Time-resolved interactome profiling deconvolutes secretory protein quality control dynamics. Molecular systems biology 20 (9) (2024)
Eli Fritz McDonald, Minsoo Kim, John A Olson, Jens Meiler, Lars Plate
Proteostasis Landscapes of Selective versus Poorly Responsive CFTR Variants Reveals Structural Vulnerabilities to Correction. bioRxiv : the preprint server for biology (2024)
Eli Fritz McDonald, Kathryn E Oliver, Jonathan P Schlebach, Jens Meiler, Lars Plate
Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants. PloS one 19 (1) (2024)
Eli Fritz McDonald, Kathryn E Oliver, Jonathan P Schlebach, Jens Meiler, Lars Plate
Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants. PloS one 19 (1) (2024)
Jonathan P Davies, Lars Plate
The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis. bioRxiv : the preprint server for biology (2024)
Jonathan P Davies, Lars Plate
The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis. bioRxiv : the preprint server for biology (2024)
Jonathan P Davies, Lars Plate
The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis. bioRxiv : the preprint server for biology (2024)
Jonathan P Davies, Lars Plate
The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis. bioRxiv : the preprint server for biology (2024)
Jonathan P Davies, Lars Plate
The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis. bioRxiv : the preprint server for biology (2024)
Eli Fritz McDonald, Kathryn E Oliver, Jonathan P Schlebach, Jens Meiler, Lars Plate
Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants. PloS one 19 (1) (2024)
Christian L Egly, Lea Barny, Tri Do, Eli Fritz McDonald, Lars Plate, Björn C Knollmann
The proteostasis interactomes of trafficking-deficient K V 11.1 variants associated with Long QT Syndrome and pharmacological chaperone rescue. bioRxiv : the preprint server for biology (2024)
Jonathan P Davies, Lars Plate
The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis. bioRxiv : the preprint server for biology (2024)
Christian L Egly, Lea Barny, Tri Do, Eli Fritz McDonald, Lars Plate, Björn C Knollmann
The proteostasis interactomes of trafficking-deficient K V 11.1 variants associated with Long QT Syndrome and pharmacological chaperone rescue. bioRxiv : the preprint server for biology (2024)
Eli Fritz McDonald, Kathryn E Oliver, Jonathan P Schlebach, Jens Meiler, Lars Plate
Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants. PloS one 19 (1) (2024)
Madison T Wright, Bibek Timalsina, Valeria Garcia Lopez, Jake N Hermanson, Sarah Garcia, Lars Plate
Time-resolved interactome profiling deconvolutes secretory protein quality control dynamics. Molecular systems biology (2024)
Minsoo Kim, Eli Fritz McDonald, Carleen Mae P Sabusap, Bibek Timalsina, Disha Joshi, Jeong S Hong, Andras Rab, Eric J Sorscher, Lars Plate
Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics. bioRxiv : the preprint server for biology (2023)
Jonathan P Davies, Athira Sivadas, Katherine R Keller, Richard J H Wojcikiewicz, Lars Plate
SARS-CoV-2 Nonstructural Proteins 3 and 4 tune the Unfolded Protein Response. bioRxiv : the preprint server for biology (2023)
Younis Hazari, Hery Urra, Valeria A Garcia Lopez, Javier Diaz, Giovanni Tamburini, Mateus Milani, Philippe Pihan, Sylvere Durand, Fanny Aprahamia, Reese Baxter, Menghao Huang, X Charlie Dong, Helena Vihinen, Ana Batista-Gonzalez, Patricio Godoy, Alfredo Criollo, Vlad Ratziu, Fabienne Foufelle, Jan G Hengstler, Eija Jokitalo, Béatrice Bailly-Maitre, Jessica L Maiers, Lars Plate, Guido Kroemer, Claudio Hetz
The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis. bioRxiv : the preprint server for biology (2023)
Eli Fritz McDonald, Kathryn E Oliver, Jonathan P Schlebach, Jens Meiler, Lars Plate
Benchmarking AlphaMissense Pathogenicity Predictions Against Cystic Fibrosis Variants. bioRxiv : the preprint server for biology (2023)
Eli Fritz McDonald, Jens Meiler, Lars Plate
CFTR Folding: From Structure and Proteostasis to Cystic Fibrosis Personalized Medicine. ACS chemical biology (2023)
Younis Hazari, Hery Urra, Valeria A Garcia Lopez, Javier Diaz, Giovanni Tamburini, Mateus Milani, Philippe Pihan, Sylvere Durand, Fanny Aprahamia, Reese Baxter, Menghao Huang, X Charlie Dong, Helena Vihinen, Ana Batista-Gonzalez, Patricio Godoy, Alfredo Criollo, Vlad Ratziu, Fabienne Foufelle, Jan G Hengstler, Eija Jokitalo, Béatrice Bailly-Maitre, Jessica L Maiers, Lars Plate, Guido Kroemer, Claudio Hetz
The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis. bioRxiv : the preprint server for biology (2023)
Dongsheng Han, Samantha H Schaffner, Jonathan P Davies, Mary Lauren Benton, Lars Plate, Jared T Nordman
BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels. Proceedings of the National Academy of Sciences of the United States of America 120 (39) (2023)
Minsoo Kim, Eli Fritz McDonald, Carleen Mae P Sabusap, Bibek Timalsina, Disha Joshi, Jeong S Hong, Andras Rab, Eric J Sorscher, Lars Plate
Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics. bioRxiv : the preprint server for biology (2023)
Dongsheng Han, Samantha H Schaffner, Jonathan P Davies, Mary Lauren Benton, Lars Plate, Jared T Nordman
BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels. bioRxiv : the preprint server for biology (2023)
Minsoo Kim, Eli Fritz McDonald, Carleen Mae P Sabusap, Bibek Timalsina, Disha Joshi, Jeong S Hong, Andras Rab, Eric J Sorscher, Lars Plate
Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics. bioRxiv : the preprint server for biology (2023)
Jonathan P Davies, Athira Sivadas, Katherine R Keller, Richard J H Wojcikiewicz, Lars Plate
SARS-CoV-2 Nonstructural Proteins 3 and 4 tune the Unfolded Protein Response. bioRxiv : the preprint server for biology (2023)
Athira Sivadas, Eli Fritz McDonald, Sydney O Shuster, Caitlin M Davis, Lars Plate
Site-Specific Crosslinking Reveals Phosphofructokinase-L Inhibition Drives Self-Assembly and Attenuation of Protein Interactions. bioRxiv : the preprint server for biology (2023)
Jonathan P Davies, Athira Sivadas, Katherine R Keller, Brynn K Roman, Richard J H Wojcikiewicz, Lars Plate
Expression of SARS-CoV-2 Nonstructural Proteins 3 and 4 Can Tune the Unfolded Protein Response in Cell Culture. Journal of proteome research (2023)
Jonathan P Davies, Athira Sivadas, Katherine R Keller, Richard J H Wojcikiewicz, Lars Plate
SARS-CoV-2 Nonstructural Proteins 3 and 4 tune the Unfolded Protein Response. bioRxiv : the preprint server for biology (2023)
Eli Fritz McDonald, Hope Woods, Shannon T Smith, Minsoo Kim, Clara T Schoeder, Lars Plate, Jens Meiler
Structural Comparative Modeling of Multi-Domain F508del CFTR. Biomolecules 12 (3) (2022)
Adam L Sanders, Jake N Hermanson, David C Samuels, Lars Plate, Charles R Sanders
Compendium of proteins containing segments that exhibit zero-tolerance to amino acid variation in humans. Protein science : a publication of the Protein Society 31 (9) (2022)
Felipe Cabral-Miranda, Giovanni Tamburini, Gabriela Martinez, Alvaro O Ardiles, Danilo B Medinas, Yannis Gerakis, Mei-Li Diaz Hung, René Vidal, Matias Fuentealba, Tim Miedema, Claudia Duran-Aniotz, Javier Diaz, Cristobal Ibaceta-Gonzalez, Carleen M Sabusap, Francisca Bermedo-Garcia, Paula Mujica, Stuart S Adamson, Kaitlyn Vitangcol, Hernan Huerta, Xu Zhang, Tomohiro Nakamura, Sergio Pablo Sardi, Stuart A Lipton, Brian K Kennedy, Juan Pablo Henriquez, J Cesar Cárdenas, Lars Plate, Adrián G Palacios, Claudio Hetz
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging. The EMBO journal 41 (22) (2022)
Katherine M Almasy, Jonathan P Davies, Samantha M Lisy, Reyhaneh Tirgar, Sirena C Tran, Lars Plate
Small-molecule endoplasmic reticulum proteostasis regulator acts as a broad-spectrum inhibitor of dengue and Zika virus infections. Proceedings of the National Academy of Sciences of the United States of America 118 (3) (2021)
Danilo B Medinas, Sajid Malik, Esra Yıldız-Bölükbaşı, Janina Borgonovo, Mirva J Saaranen, Hery Urra, Eduardo Pulgar, Muhammad Afzal, Darwin Contreras, Madison T Wright, Felipe Bodaleo, Gabriel Quiroz, Pablo Rozas, Sara Mumtaz, Rodrigo Díaz, Carlos Rozas, Felipe Cabral-Miranda, Ricardo Piña, Vicente Valenzuela, Ozgun Uyan, Christopher Reardon, Ute Woehlbier, Robert H Brown, Miguel Sena-Esteves, Christian Gonzalez-Billault, Bernardo Morales, Lars Plate, Lloyd W Ruddock, Miguel L Concha, Claudio Hetz, Aslıhan Tolun
Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis. The EMBO journal 41 (2) (2021)
Oktay Kirak, Eugene Ke, Kevin Y Yang, Anna Schwarz, Lars Plate, Amy Nham, Justin R Abadejos, Anna Valencia, R Luke Wiseman, Kathy O Lui, Manching Ku
Premature Activation of Immune Transcription Programs in Autoimmune-Predisposed Mouse Embryonic Stem Cells and Blastocysts. International journal of molecular sciences 21 (16) (2020)
Madison T Wright, Logan Kouba, Lars Plate
Thyroglobulin interactome profiling defines altered proteostasis topology associated with thyroid dyshormonogenesis. Molecular & cellular proteomics : MCP (2020)
Jonathan P Davies, Katherine M Almasy, Eli F McDonald, Lars Plate
Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies. ACS infectious diseases 6 (12) (2020)
Julia M D Grandjean, Lars Plate, Richard I Morimoto, Michael J Bollong, Evan T Powers, R Luke Wiseman
Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA Sequencing. ACS chemical biology 14 (4) (2019)
Ryan J Paxman, Lars Plate, Erik A Blackwood, Chris Glembotski, Evan T Powers, R Luke Wiseman, Jeffrey W Kelly
Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins. eLife 7 (2018)
Joseph D Schonhoft, Cecilia Monteiro, Lars Plate, Yvonne S Eisele, Jeffrey W Kelly, Daniel Boland, Christopher G Parker, Benjamin F Cravatt, Sergio Teruya, Stephen T Helmke, Mathew S Maurer, John L Berk, Yoshiki Sekijima, Marta Novais, Teresa Coelho, Evan T Powers, Jeffery W Kelly
Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients. Science translational medicine 9 (407) (2018)
Heike Kroeger, Neil J Grimsey, Ryan J Paxman, Wei-Chieh Chiang, Lars Plate, Ying Jones, Peter X Shaw, JoAnn Trejo, Stephen H Tsang, Evan T Powers, Jeffrey W Kelly, R Luke Wiseman, Jonathan H Lin
The unfolded protein response regulator ATF6 promotes mesodermal differentiation. Science signaling 11 (517) (2018)
Lars Plate, Ryan J Paxman, R Luke Wiseman, Jeffery W Kelly
Modulating protein quality control. eLife 5 (2016)
Lars Plate, Christina B Cooley, John J Chen, Ryan J Paxman, Ciara M Gallagher, Franck Madoux, Joseph C Genereux, Wesley Dobbs, Dan Garza, Timothy P Spicer, Louis Scampavia, Steven J Brown, Hugh Rosen, Evan T Powers, Peter Walter, Peter Hodder, R Luke Wiseman, Jeffery W Kelly
Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation. eLife 5 (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Lars Plate