Liang Wu

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 20

Top Venues

Journal of the American Chemical Society

Nature communications

Chemistry (Weinheim an der Bergstrasse, Germany)

Nature chemical biology

Rosalind Franklin Institute

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Rosalind Franklin Institute May 04 2020

United Kingdom

Wellcome Trust Sir Henry Dale Fellow

University of York Nov 04 2013 - Feb 11 2020

United Kingdom

PDRA - Prof. Gideon Davies :: Structural Biology Lab

Education History

University of Cambridge Oct 01 2009 - Oct 01 2013

United Kingdom

PHD :: Chemistry

Publications

Courtney J Mycroft-West, Sahar Abdelkarim, Helen M E Duyvesteyn, Neha S Gandhi, Mark A Skidmore, Raymond J Owens, Liang Wu
Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1. Nature communications 15 (1) (2024)
Courtney J Mycroft-West, Sahar Abdelkarim, Helen M E Duyvesteyn, Neha S Gandhi, Mark A Skidmore, Raymond J Owens, Liang Wu
Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1. Nature communications 15 (1) (2024)
Courtney J Mycroft-West, Sahar Abdelkarim, Helen M E Duyvesteyn, Neha S Gandhi, Mark A Skidmore, Raymond J Owens, Liang Wu
Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1. Nature communications 15 (1) (2024)
Courtney J Mycroft-West, Sahar Abdelkarim, Helen M E Duyvesteyn, Neha S Gandhi, Mark A Skidmore, Raymond J Owens, Liang Wu
Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1. Nature communications 15 (1) (2024)
Yurong Chen, Adrianus M C H van den Nieuwendijk, Liang Wu, Elisha Moran, Foteini Skoulikopoulou, Vera van Riet, Herman S Overkleeft, Gideon J Davies, Zach W B Armstrong
Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B. Journal of the American Chemical Society 146 (1) (2023)
Yurong Chen, Adrianus M C H van den Nieuwendijk, Liang Wu, Elisha Moran, Foteini Skoulikopoulou, Vera van Riet, Herman S Overkleeft, Gideon J Davies, Zach W B Armstrong
Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B. Journal of the American Chemical Society 146 (1) (2023)
Yurong Chen, Adrianus M C H van den Nieuwendijk, Liang Wu, Elisha Moran, Foteini Skoulikopoulou, Vera van Riet, Herman S Overkleeft, Gideon J Davies, Zach W B Armstrong
Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B. Journal of the American Chemical Society 146 (1) (2023)
Yurong Chen, Adrianus M C H van den Nieuwendijk, Liang Wu, Elisha Moran, Foteini Skoulikopoulou, Vera van Riet, Herman S Overkleeft, Gideon J Davies, Zach W B Armstrong
Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B. Journal of the American Chemical Society 146 (1) (2023)
Yurong Chen, Adrianus M C H van den Nieuwendijk, Liang Wu, Elisha Moran, Foteini Skoulikopoulou, Vera van Riet, Herman S Overkleeft, Gideon J Davies, Zach W B Armstrong
Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B. Journal of the American Chemical Society 146 (1) (2023)
Yurong Chen, Adrianus M C H van den Nieuwendijk, Liang Wu, Elisha Moran, Foteini Skoulikopoulou, Vera van Riet, Herman S Overkleeft, Gideon J Davies, Zach W B Armstrong
Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B. Journal of the American Chemical Society 146 (1) (2023)
Yurong Chen, Adrianus M C H van den Nieuwendijk, Liang Wu, Elisha Moran, Foteini Skoulikopoulou, Vera van Riet, Herman S Overkleeft, Gideon J Davies, Zach W B Armstrong
Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B. Journal of the American Chemical Society (2023)
Yurong Chen, Adrianus M C H van den Nieuwendijk, Liang Wu, Elisha Moran, Foteini Skoulikopoulou, Vera van Riet, Herman S Overkleeft, Gideon J Davies, Zach W B Armstrong
Molecular Basis for Inhibition of Heparanases and β-Glucuronidases by Siastatin B. Journal of the American Chemical Society 146 (1) (2023)
Ken Kok, Chi-Lin Kuo, Rebecca E Katzy, Lindsey T Lelieveld, Liang Wu, Véronique Roig-Zamboni, Gijsbert A van der Marel, Jeroen D C Codée, Gerlind Sulzenbacher, Gideon J Davies, Herman S Overkleeft, Johannes M F G Aerts, Marta Artola
1,6- epi -Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal α-Glucosidase Stabilizer for the Treatment of Pompe Disease. Journal of the American Chemical Society 144 (32) (2022)
Casper de Boer, Zachary Armstrong, Vincent A J Lit, Uri Barash, Gijs Ruijgrok, Ilanit Boyango, Merle M Weitzenberg, Sybrin P Schröder, Alexi J C Sarris, Nico J Meeuwenoord, Pedro Bule, Yasmine Kayal, Neta Ilan, Jeroen D C Codée, Israel Vlodavsky, Herman S Overkleeft, Gideon J Davies, Liang Wu
Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proceedings of the National Academy of Sciences of the United States of America 119 (31) (2022)
Mohit Chhabra, Jennifer C Wilson, Liang Wu, Gideon J Davies, Neha S Gandhi, Vito Ferro
Structural Insights into Pixatimod (PG545) Inhibition of Heparanase, a Key Enzyme in Cancer and Viral Infections. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (11) (2022)
Liang Wu, Norbert Wimmer, Gideon J Davies, Vito Ferro
Structural insights into heparanase activity using a fluorogenic heparan sulfate disaccharide. Chemical communications (Cambridge, England) 56 (89) (2021)
Rhianna J Rowland, Yurong Chen, Imogen Breen, Liang Wu, Wendy A Offen, Thomas J Beenakker, Qin Su, Adrianus M C H van den Nieuwendijk, Johannes M F G Aerts, Marta Artola, Herman S Overkleeft, Gideon J Davies
Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (66) (2021)
Zach W B Armstrong, Chi-Lin Kuo, Daniël Lahav, Bing Liu, Rachel Johnson, Thomas J M Beenakker, Casper de Boer, Chung-Sing Wong, Erwin R van Rijssel, Marjoke F Debets, Bogdan I Florea, Colin Hissink, Rolf G Boot, Paul P Geurink, Huib Ovaa, Mario van der Stelt, Jeroen D C Codée, Jeroen D C Codée, Johannes M F G Aerts, Liang Wu, Herman S Overkleeft, Gideon J Davies
Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors. Journal of the American Chemical Society 142 (30) (2020)
Pedro Bule, Léa Chuzel, Elena Blagova, Liang Wu, Melissa A Gray, Bernard Henrissat, Erdmann Rapp, Carolyn R Bertozzi, Christopher H Taron, Gideon J Davies
Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action. Nature communications 10 (1) (2019)
Liang Wu, Jianbing Jiang, Yi Jin, Wouter W Kallemeijn, Chi-Lin Kuo, Marta Artola, Wei Dai, Cas van Elk, Marco van Eijk, Gijsbert A van der Marel, Jeroen D C Codée, Bogdan I Florea, Johannes M F G Aerts, Herman S Overkleeft, Gideon J Davies
Activity-based probes for functional interrogation of retaining β-glucuronidases. Nature chemical biology 13 (8) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Liang Wu