Paul P Geurink (Paul Geurink)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 20

Top Venues

Journal of medicinal chemistry

Nature communications

Journal of the American Chemical Society

Organic & biomolecular chemistry

Leiden Univesity Medical Center (LUMC)

Universiteit Leiden (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Leiden Univesity Medical Center (LUMC) Jul 01 2016

Netherlands

Assistant Professor :: Chemical Immunology

Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis May 01 2014 - Jun 30 2016

Netherlands

Senior Postdoc :: Cell Biology

Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis Aug 01 2010 - Apr 30 2014

Netherlands

Postdoc :: Cell Biology

Education History

Universiteit Leiden - Mar 21 2006

Netherlands

MSC :: Chemistry

Publications

Yuqing Jia, Merve Oyken, Robbert Q Kim, Rayman T N Tjokrodirijo, Arnoud H de Ru, Antonius P A Janssen, Stephan M Hacker, Peter A van Veelen, Paul P Geurink, Aysegul Sapmaz
Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell. Journal of medicinal chemistry 67 (10) (2024)
Yuqing Jia, Merve Oyken, Robbert Q Kim, Rayman T N Tjokrodirijo, Arnoud H de Ru, Antonius P A Janssen, Stephan M Hacker, Peter A van Veelen, Paul P Geurink, Aysegul Sapmaz
Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell. Journal of medicinal chemistry 67 (10) (2024)
Yuqing Jia, Merve Oyken, Robbert Q Kim, Rayman T N Tjokrodirijo, Arnoud H de Ru, Antonius P A Janssen, Stephan M Hacker, Peter A van Veelen, Paul P Geurink, Aysegul Sapmaz
Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell. Journal of medicinal chemistry 67 (10) (2024)
Yuqing Jia, Merve Oyken, Robbert Q Kim, Rayman T N Tjokrodirijo, Arnoud H de Ru, Antonius P A Janssen, Stephan M Hacker, Peter A van Veelen, Paul P Geurink, Aysegul Sapmaz
Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell. Journal of medicinal chemistry 67 (10) (2024)
Yuqing Jia, Merve Oyken, Robbert Q Kim, Rayman T N Tjokrodirijo, Arnoud H de Ru, Antonius P A Janssen, Stephan M Hacker, Peter A van Veelen, Paul P Geurink, Aysegul Sapmaz
Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell. Journal of medicinal chemistry (2024)
Magdalena Szczesna, Yizhou Huang, Rachel Lacoursiere, Francesca Bonini, Vito Pol, Fulya Koc, Beatrice Ward, Paul P Geurink, Jonathan N Pruneda, Teresa Thurston
Dedicated bacterial esterases reverse lipopolysaccharide ubiquitylation to block immune sensing. Research square (2023)
Jin Gan, Adán Pinto-Fernández, Dennis Flierman, Jimmy J L L Akkermans, Darragh P O'Brien, Helene Greenwood, Hannah Claire Scott, Günter Fritz, Klaus-Peter Knobeloch, Jacques Neefjes, Hans van Dam, Huib Ovaa, Hidde L Ploegh, Benedikt Mathias Kessler, Paul P Geurink, Aysegul Sapmaz
USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism. Proceedings of the National Academy of Sciences of the United States of America 120 (50) (2023)
Daniël van der Gracht, Rhianna J Rowland, Véronique Roig-Zamboni, Maria J Ferraz, Max Louwerse, Paul P Geurink, Johannes M F G Aerts, Gerlind Sulzenbacher, Gideon J Davies, Herman S Overkleeft, Marta Artola
Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases. Chemical science 14 (34) (2023)
Bianca D M van Tol, Bjorn R van Doodewaerd, Guinevere S M Lageveen-Kammeijer, Bas C Jansen, Cami M P Talavera Ormeño, Paul J M Hekking, Aysegul Sapmaz, Robbert Q Kim, Angeliki Moutsiopoulou, David Komander, Dana L E Vergoossen, Gerbrand J van der Heden van Noort, Huib Ovaa, Paul P Geurink
Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes. Nature communications 14 (1) (2023)
Jin Gan, Jelle de Vries, Jimmy J L L Akkermans, Yassene Mohammed, Rayman T N Tjokrodirijo, Arnoud H de Ru, Robbert Q Kim, David A Vargas, Vito Pol, Rudi Fasan, Peter A van Veelen, Jacques Neefjes, Hans van Dam, Huib Ovaa, Aysegul Sapmaz, Paul P Geurink
Cellular Validation of a Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2. ACS chemical biology (2023)
Bianca D M van Tol, Bjorn R van Doodewaerd, Guinevere S M Lageveen-Kammeijer, Bas C Jansen, Cami M P Talavera Ormeño, Paul J M Hekking, Aysegul Sapmaz, Robbert Q Kim, Angeliki Moutsiopoulou, David Komander, Dana L E Vergoossen, Gerbrand J van der Heden van Noort, Huib Ovaa, Paul P Geurink
Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes. Nature communications 14 (1) (2023)
Bianca D M van Tol, Bjorn R van Doodewaerd, Guinevere S M Lageveen-Kammeijer, Bas C Jansen, Cami M P Talavera Ormeño, Paul J M Hekking, Aysegul Sapmaz, Robbert Q Kim, Angeliki Moutsiopoulou, David Komander, Dana L E Vergoossen, Gerbrand J van der Heden van Noort, Huib Ovaa, Paul P Geurink
Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes. Nature communications 14 (1) (2023)
Yuqing Jia, Robbert Q Kim, Raymond Kooij, Huib Ovaa, Aysegul Sapmaz, Paul P Geurink
Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput. Journal of medicinal chemistry 65 (19) (2022)
Alexander F Schubert, Justine V Nguyen, Tyler G Franklin, Paul P Geurink, Cameron G Roberts, Daniel J Sanderson, Lauren N Miller, Huib Ovaa, Kay Hofmann, Jonathan N Pruneda, David Komander
Identification and characterization of diverse OTU deubiquitinases in bacteria. The EMBO journal 39 (15) (2020)
Donghyuk Shin, Rukmini Mukherjee, Diana Grewe, Denisa Bojkova, Kheewoong Baek, Anshu Bhattacharya, Laura Schulz, Marek Widera, Ahmad Reza Mehdipour, Georg Tascher, Paul P Geurink, Alexander Wilhelm, Gerbrand J van der Heden van Noort, Huib Ovaa, Stefan Müller, Klaus-Peter Knobeloch, Krishnaraj Rajalingam, Brenda A Schulman, Jindrich Cinatl, Gerhard Hummer, Sandra Ciesek, Ivan Đikić
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. Nature 587 (7835) (2020)
Zach W B Armstrong, Chi-Lin Kuo, Daniël Lahav, Bing Liu, Rachel Johnson, Thomas J M Beenakker, Casper de Boer, Chung-Sing Wong, Erwin R van Rijssel, Marjoke F Debets, Bogdan I Florea, Colin Hissink, Rolf G Boot, Paul P Geurink, Huib Ovaa, Mario van der Stelt, Jeroen D C Codée, Jeroen D C Codée, Johannes M F G Aerts, Liang Wu, Herman S Overkleeft, Gideon J Davies
Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors. Journal of the American Chemical Society 142 (30) (2020)
Raymond Kooij, Sijia Liu, Aysegul Sapmaz, Bo-Tao Xin, George M C Janssen, Peter A van Veelen, Huib Ovaa, Peter Ten Dijke, Paul P Geurink
Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos. Journal of the American Chemical Society 142 (39) (2020)
Bo-Tao Xin, Bianca D M van Tol, Huib Ovaa, Paul P Geurink
Native chemical ligation at methionine bioisostere norleucine allows for N-terminal chemical protein ligation. Organic & biomolecular chemistry 16 (34) (2019)
Sijia Liu, Román González-Prieto, Mengdi Zhang, Paul P Geurink, Raymond Kooij, Prasanna Vasudevan Iyengar, Maarten van Dinther, Erik Bos, Xiaobing Zhang, Sylvia E Le Dévédec, Bob van de Water, Roman I Koning, Hong-Jian Zhu, Wilma E Mesker, Alfred C O Vertegaal, Huib Ovaa, Long Zhang, John W M Martens, Peter Ten Dijke
Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (6) (2019)
Bo-Tao Xin, Jin Gan, Daniel J Fernandez, Klaus-Peter Knobeloch, Paul P Geurink, Huib Ovaa
Total chemical synthesis of murine ISG15 and an activity-based probe with physiological binding properties. Organic & biomolecular chemistry 17 (48) (2019)

Paul P Geurink.css-eqlu8i{font-size:small;padding-left:4px;} (Paul Geurink)

Publication Activity (10 Years)

Top Topics

Top Venues

Paul P Geurink (Paul Geurink)