Marta Artola

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Venues

Journal of the American Chemical Society

Chemistry (Weinheim an der Bergstrasse, Germany)

Chemical science

ACS chemical biology

Leiden University

Universidad Complutense de Madrid (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Leiden University Feb 01 2019

Netherlands

Assistant Professor :: Medical Biochemistry

Universiteit Leiden Mar 01 2015 - Jan 31 2019

Netherlands

Post-doctoral associate :: Bio-organic Synthesis

Education History

Universidad Complutense de Madrid

Spain

PHD :: Química Organica

Scripps Research Institute Aug 01 2013 - Nov 30 2013

United States

PHD :: Prof. Phil S. Baran Lab

Technische Universitat Munchen Institut fur Luft- und Raumfahrt Oct 01 2012 - Dec 20 2012

Germany

PHD :: Prof. Stephan A. Sieber Lab

Publications

Marta Artola, Johannes M F G Aerts, Gijsbert A van der Marel, Carme Rovira, Jeroen D C Codée, Gideon J Davies, Herman S Overkleeft
From Mechanism-Based Retaining Glycosidase Inhibitors to Activity-Based Glycosidase Profiling. Journal of the American Chemical Society (2024)
Melissa Thaler, Tim P Ofman, Ken Kok, Jurriaan J A Heming, Elisha Moran, Isabelle Pickles, Anouk A Leijs, Adrianus M C H van den Nieuwendijk, Richard J B H N van den Berg, Gijs Ruijgrok, Zach W B Armstrong, Clarisse Salgado-Benvindo, Dennis K Ninaber, Eric J Snijder, Constant A A van Boeckel, Marta Artola, Gideon J Davies, Herman S Overkleeft, Martijn J van Hemert
Epi -Cyclophellitol Cyclosulfate, a Mechanism-Based Endoplasmic Reticulum α-Glucosidase II Inhibitor, Blocks Replication of SARS-CoV-2 and Other Coronaviruses. ACS central science 10 (8) (2024)
Tim P Ofman, Jurriaan J A Heming, Alba Nin-Hill, Florian Küllmer, Elisha Moran, Megan Bennett, Roy Steneker, Anne-Mei Klein, Gijs Ruijgrok, Ken Kok, Zach W B Armstrong, Johannes M F G Aerts, Gijsbert A van der Marel, Carme Rovira, Gideon J Davies, Marta Artola, Jeroen D C Codée, Herman S Overkleeft
Conformational and Electronic Variations in 1,2- and 1,5a-Cyclophellitols and their Impact on Retaining α-Glucosidase Inhibition. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Melissa Thaler, Tim P Ofman, Ken Kok, Jurriaan J A Heming, Elisha Moran, Isabelle Pickles, Anouk A Leijs, Adrianus M C H van den Nieuwendijk, Richard J B H N van den Berg, Gijs Ruijgrok, Zach W B Armstrong, Clarisse Salgado-Benvindo, Dennis K Ninaber, Eric J Snijder, Constant A A van Boeckel, Marta Artola, Gideon J Davies, Herman S Overkleeft, Martijn J van Hemert
Epi -Cyclophellitol Cyclosulfate, a Mechanism-Based Endoplasmic Reticulum α-Glucosidase II Inhibitor, Blocks Replication of SARS-CoV-2 and Other Coronaviruses. ACS central science 10 (8) (2024)
Tim P Ofman, Jurriaan J A Heming, Alba Nin-Hill, Florian Küllmer, Elisha Moran, Megan Bennett, Roy Steneker, Anne-Mei Klein, Gijs Ruijgrok, Ken Kok, Zach W B Armstrong, Johannes M F G Aerts, Gijsbert A van der Marel, Carme Rovira, Gideon J Davies, Marta Artola, Jeroen D C Codée, Herman S Overkleeft
Conformational and Electronic Variations in 1,2- and 1,5a-Cyclophellitols and their Impact on Retaining α-Glucosidase Inhibition. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (31) (2024)
Qin Su, Max Louwerse, Rob F Lammers, Elmer Maurits, Max Janssen, Rolf G Boot, Valentina Borlandelli, Wendy A Offen, Daniël Linzel, Sybrin P Schröder, Gideon J Davies, Herman S Overkleeft, Marta Artola, Johannes M F G Aerts
Selective labelling of GBA2 in cells with fluorescent β-d-arabinofuranosyl cyclitol aziridines. Chemical science (2024)
Tim P Ofman, Jurriaan J A Heming, Alba Nin-Hill, Florian Küllmer, Elisha Moran, Megan Bennett, Roy Steneker, Anne-Mei Klein, Gijs Ruijgrok, Ken Kok, Zach W B Armstrong, Johannes M F G Aerts, Gijsbert A van der Marel, Carme Rovira, Gideon J Davies, Marta Artola, Jeroen D C Codée, Herman S Overkleeft
Conformational and Electronic Variations in 1,2- and 1,5a-Cyclophellitols and their Impact on Retaining α-Glucosidase Inhibition. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (31) (2024)
Valentina Borlandelli, Wendy Offen, Olga Moroz, Alba Nin-Hill, Nicholas McGregor, Lars Binkhorst, Akihiro Ishiwata, Zach W B Armstrong, Marta Artola, Carme Rovira, Gideon J Davies, Herman S Overkleeft
β-l- Arabino furano-cyclitol Aziridines Are Covalent Broad-Spectrum Inhibitors and Activity-Based Probes for Retaining β-l-Arabinofuranosidases. ACS chemical biology (2023)
Daniël van der Gracht, Rhianna J Rowland, Véronique Roig-Zamboni, Maria J Ferraz, Max Louwerse, Paul P Geurink, Johannes M F G Aerts, Gerlind Sulzenbacher, Gideon J Davies, Herman S Overkleeft, Marta Artola
Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases. Chemical science 14 (34) (2023)
Alexandra Males, Ken Kok, Alba Nin-Hill, Nicky de Koster, Sija van den Beukel, Thomas J M Beenakker, Gijsbert A van der Marel, Jeroen D C Codée, Johannes M F G Aerts, Herman S Overkleeft, Carme Rovira, Gideon J Davies, Marta Artola
Trans -cyclosulfamidate mannose-configured cyclitol allows isoform-dependent inhibition of GH47 α-d-mannosidases through a bump-hole strategy. Chemical science 14 (46) (2023)
Ken Kok, Chi-Lin Kuo, Rebecca E Katzy, Lindsey T Lelieveld, Liang Wu, Véronique Roig-Zamboni, Gijsbert A van der Marel, Jeroen D C Codée, Gerlind Sulzenbacher, Gideon J Davies, Herman S Overkleeft, Johannes M F G Aerts, Marta Artola
1,6- epi -Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal α-Glucosidase Stabilizer for the Treatment of Pompe Disease. Journal of the American Chemical Society 144 (32) (2022)
Qin Su, Sybrin P Schröder, Lindsey T Lelieveld, Maria J Ferraz, Marri Verhoek, Rolf G Boot, Herman S Overkleeft, Johannes M F G Aerts, Marta Artola, Chi-Lin Kuo
Xylose-Configured Cyclophellitols as Selective Inhibitors for Glucocerebrosidase. Chembiochem : a European journal of chemical biology 22 (21) (2021)
Yurong Chen, Zach W B Armstrong, Marta Artola, Bogdan I Florea, Chi-Lin Kuo, Casper de Boer, Mikkel S Rasmussen, Maher Abou Hachem, Gijsbert A van der Marel, Jeroen D C Codée, Johannes M F G Aerts, Gideon J Davies, Herman S Overkleeft
Activity-Based Protein Profiling of Retaining α-Amylases in Complex Biological Samples. Journal of the American Chemical Society 143 (5) (2021)
Sonia Huecas, Lidia Araújo-Bazán, Federico M Ruiz, Laura B Ruiz-Ávila, R Fernando Martínez, Andrea Escobar-Peña, Marta Artola, Henar Vázquez-Villa, Mar Martín-Fontecha, Carlos Fernández-Tornero, Maria L López-Rodríguez, José M Andreu
Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery. Journal of medicinal chemistry 64 (9) (2021)
Ken Kok, Kimberley C Zwiers, Rolf G Boot, Hermen S Overkleeft, Johannes M F G Aerts, Marta Artola
Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions. Biomolecules 11 (2) (2021)
Rhianna J Rowland, Yurong Chen, Imogen Breen, Liang Wu, Wendy A Offen, Thomas J Beenakker, Qin Su, Adrianus M C H van den Nieuwendijk, Johannes M F G Aerts, Marta Artola, Herman S Overkleeft, Gideon J Davies
Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (66) (2021)
Nicholas G S McGregor, Joan Coines, Valentina Borlandelli, Satoko Amaki, Marta Artola, Alba Nin-Hill, Daniël Linzel, Chihaya Yamada, Takatoshi Arakawa, Akihiro Ishiwata, Yukishige Ito, Gijsbert A van der Marel, Jeroen D C Codée, Shinya Fushinobu, Herman S Overkleeft, Carme Rovira, Gideon J Davies
Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β-l-Arabinofuranosidase Inhibitor. Angewandte Chemie (International ed. in English) 60 (11) (2021)
Nicholas G S McGregor, Marta Artola, Alba Nin-Hill, Daniël Linzel, Mireille Haon, Jos Reijngoud, Arthur Ram, Marie-Noëlle Rosso, Gijsbert A van der Marel, Jeroen D C Codée, Gilles P van Wezel, Jean-Guy Berrin, Carme Rovira, Herman S Overkleeft, Gideon J Davies
Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α-l-Arabinofuranosidases. Journal of the American Chemical Society 142 (10) (2020)
Nicholas G S McGregor, Johan P Turkenburg, Kristian B R Mørkeberg Krogh, Jens Erik Nielsen, Marta Artola, Keith A Stubbs, Herman S Overkleeft, Gideon J Davies
Structure of a GH51 α-L-arabinofuranosidase from Meripilus giganteus: conserved substrate recognition from bacteria to fungi. Acta crystallographica. Section D, Structural biology 76 (Pt 11) (2020)
Chi-Lin Kuo, Wouter W Kallemeijn, Lindsey T Lelieveld, Mina Mirzaian, Iris Zoutendijk, Ayelet Vardi, Anthony H Futerman, Annemarie H Meijer, Herman P Spaink, Herman S Overkleeft, Johannes M F G Aerts, Marta Artola
In vivo inactivation of glycosidases by conduritol B epoxide and cyclophellitol as revealed by activity-based protein profiling. The FEBS journal 286 (3) (2019)
Parth B Jariwala, Samuel J Pellock, Dennis Goldfarb, Erica W Cloer, Marta Artola, Joshua B Simpson, Aadra P Bhatt, William G Walton, Lee R Roberts, Michael B Major, Gideon J Davies, Herman S Overkleeft, Matthew R Redinbo
Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling. ACS chemical biology 15 (1) (2019)
Marta Artola, Chi-Lin Kuo, Lindsey T Lelieveld, Rhianna J Rowland, Gijsbert A van der Marel, Jeroen D C Codée, Rolf G Boot, Gideon J Davies, Johannes M F G Aerts, Herman S Overkleeft
Functionalized Cyclophellitols Are Selective Glucocerebrosidase Inhibitors and Induce a Bona Fide Neuropathic Gaucher Model in Zebrafish. Journal of the American Chemical Society 141 (10) (2019)
Marta Artola, Shirley Wouters, Sybrin P Schröder, Casper de Boer, Yurong Chen, Rita Petracca, Adrianus M C H van den Nieuwendijk, Johannes M F G Aerts, Gijsbert A van der Marel, Jeroen D C Codée, Herman S Overkleeft
Direct Stereoselective Aziridination of Cyclohexenols with 3-Amino-2-(trifluoromethyl)quinazolin-4(3H)-one in the Synthesis of Cyclitol Aziridine Glycosidase Inhibitors. European journal of organic chemistry 2019 (6) (2019)
Lindsey T Lelieveld, Mina Mirzaian, Chi-Lin Kuo, Marta Artola, Maria J Ferraz, Remco E A Peter, Hisako Akiyama, Peter Greimel, Richard J B H N van den Berg, Herman S Overkleeft, Rolf G Boot, Annemarie H Meijer, Johannes M F G Aerts
Role of β-glucosidase 2 in aberrant glycosphingolipid metabolism: model of glucocerebrosidase deficiency in zebrafish. Journal of lipid research 60 (11) (2019)
Sybrin P Schröder, Liang Wu, Marta Artola, Thomas Hansen, Wendy A Offen, Maria J Ferraz, Kah-Yee Li, Johannes M F G Aerts, Gijsbert A van der Marel, Jeroen D C Codée, Gideon J Davies, Herman S Overkleeft
Gluco-1 H-imidazole: A New Class of Azole-Type β-Glucosidase Inhibitor. Journal of the American Chemical Society 140 (15) (2018)
Kassiani Kytidou, Jules Beekwilder, Marta Artola, Eline van Meel, Ruud H P Wilbers, Geri F Moolenaar, Nora Goosen, Maria J Ferraz, Rebecca Katzy, Patrick Voskamp, Bogdan I Florea, Cornelis H Hokke, Herman S Overkleeft, Arjen Schots, Dirk Bosch, Navraj Pannu, Johannes M F G Aerts
Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease. The Journal of biological chemistry 293 (26) (2018)
Marta Artola, Chi-Lin Kuo, Stephen A McMahon, Verena Oehler, Thomas Hansen, Martijn van der Lienden, Xu He, Hans van den Elst, Bogdan I Florea, Allison R Kermode, Gijsbert A van der Marel, Tracey M Gloster, Jeroen D C Codée, Herman S Overkleeft, Johannes M F G Aerts
New Irreversible α-l-Iduronidase Inhibitors and Activity-Based Probes. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (71) (2018)
Fredj Ben Bdira, Marta Artola, Herman S Overkleeft, Marcellus Ubbink, Johannes M F G Aerts
Distinguishing the differences in β-glycosylceramidase folds, dynamics, and actions informs therapeutic uses. Journal of lipid research 59 (12) (2018)
Liang Wu, Jianbing Jiang, Yi Jin, Wouter W Kallemeijn, Chi-Lin Kuo, Marta Artola, Wei Dai, Cas van Elk, Marco van Eijk, Gijsbert A van der Marel, Jeroen D C Codée, Bogdan I Florea, Johannes M F G Aerts, Herman S Overkleeft, Gideon J Davies
Activity-based probes for functional interrogation of retaining β-glucuronidases. Nature chemical biology 13 (8) (2017)
Marta Artola, Laura B Ruíz-Avila, R Fernando Martínez, R Fernando Martínez, Lidia Araujo-Bazán, Henar Vázquez-Villa, Mar Martín-Fontecha, María A Oliva, A Javier Martín-Galiano, Pablo Chacón, Maria L López-Rodríguez, José M Andreu, Sonia Huecas
The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitors. Chemical science 8 (2) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Marta Artola