Kim D Janda (Kim Janda)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 57

Top Topics

Molecular Dynamics Simulations

Botulinum Toxin

Structure Activity Relationship

Top Venues

Journal of the American Chemical Society

ACS chemical neuroscience

Communications biology

ACS infectious diseases

This page only lists publications with an associated author ORCID identifier.

Publications

András H Lékó, Adriana Gregory-Flores, Renata Cristina Nunes Marchette, Juan L Gomez, Janaina C M Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L Deschaine, Kimberly E Whiting, Shelley N Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D Janda, Barry Zorman, Pavel Sumazin, George F Koob, Michael Michaelides, Pietro Paolo Sanna, Leandro F Vendruscolo, Lorenzo Leggio
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Communications biology 7 (1) (2024)
András H Lékó, Adriana Gregory-Flores, Renata Cristina Nunes Marchette, Juan L Gomez, Janaina C M Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L Deschaine, Kimberly E Whiting, Shelley N Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D Janda, Barry Zorman, Pavel Sumazin, George F Koob, Michael Michaelides, Pietro Paolo Sanna, Leandro F Vendruscolo, Lorenzo Leggio
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Communications biology 7 (1) (2024)
Mingliang Lin, Lisa M Eubanks, Bin Zhou, Kim D Janda
Evaluation of a hapten conjugate vaccine against the "zombie drug" xylazine. Chemical communications (Cambridge, England) (2024)
Mingliang Lin, Lisa M Eubanks, Bin Zhou, Kim D Janda
Evaluation of a hapten conjugate vaccine against the "zombie drug" xylazine. Chemical communications (Cambridge, England) 60 (35) (2024)
András H Lékó, Adriana Gregory-Flores, Renata Cristina Nunes Marchette, Juan L Gomez, Janaina C M Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L Deschaine, Kimberly E Whiting, Shelley N Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D Janda, Barry Zorman, Pavel Sumazin, George F Koob, Michael Michaelides, Pietro Paolo Sanna, Leandro F Vendruscolo, Lorenzo Leggio
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Communications biology 7 (1) (2024)
Mingliang Lin, Lisa M Eubanks, Bin Zhou, Kim D Janda
Evaluation of a hapten conjugate vaccine against the "zombie drug" xylazine. Chemical communications (Cambridge, England) 60 (35) (2024)
András H Lékó, Adriana Gregory-Flores, Renata Cristina Nunes Marchette, Juan L Gomez, Janaina C M Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L Deschaine, Kimberly E Whiting, Shelley N Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D Janda, Barry Zorman, Pavel Sumazin, George F Koob, Michael Michaelides, Pietro Paolo Sanna, Leandro F Vendruscolo, Lorenzo Leggio
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Communications biology 7 (1) (2024)
Nishant M Karadkhelkar, Mingliang Lin, Lisa M Eubanks, Kim D Janda
Demystifying the Druggability of the MYC Family of Oncogenes. Journal of the American Chemical Society 145 (6) (2023)
Nishant M Karadkhelkar, Mingliang Lin, Lisa M Eubanks, Kim D Janda
Demystifying the Druggability of the MYC Family of Oncogenes. Journal of the American Chemical Society (2023)
Lisa M Eubanks, Tossapol Pholcharee, David Oyen, Yoshihiro Natori, Bin Zhou, Ian A Wilson, Kim D Janda
An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. ACS chemical neuroscience (2023)
Lucy Lin, Ealin N Patel, Alexander L Nielsen, Lewis D Turner, William H Tepp, Kong Nguyen, Sabine Pellett, Kim D Janda
Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease. International journal of molecular sciences 24 (5) (2023)
Mingliang Lin, Lisa M Eubanks, Nishant M Karadkhelkar, Steven Blake, Kim D Janda
Catalytic Antibody Blunts Carfentanil-Induced Respiratory Depression. ACS pharmacology & translational science 6 (5) (2023)
Nishant M Karadkhelkar, Mingliang Lin, Lisa M Eubanks, Kim D Janda
Demystifying the Druggability of the MYC Family of Oncogenes. Journal of the American Chemical Society 145 (6) (2023)
Mingliang Lin, Lisa M Eubanks, Nishant M Karadkhelkar, Steven Blake, Kim D Janda
Catalytic Antibody Blunts Carfentanil-Induced Respiratory Depression. ACS pharmacology & translational science 6 (5) (2023)
Lucy Lin, Ealin N Patel, Alexander L Nielsen, Lewis D Turner, William H Tepp, Kong Nguyen, Sabine Pellett, Kim D Janda
Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease. International journal of molecular sciences 24 (5) (2023)
Lucy Lin, Ealin N Patel, Alexander L Nielsen, Lewis D Turner, William H Tepp, Kong Nguyen, Sabine Pellett, Kim D Janda
Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease. International journal of molecular sciences 24 (5) (2023)
Lorenzo Leggio, Andras Leko, Adriana Gregory-Flores, Renata Cristina Nunes Marchette, Juan Gomez, Janaina Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara Deschaine, Kimberly Whiting, Shelley Jackson, Maria Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Kim D Janda, Barry Zorman, Pavel Sumazin, George Koob, Michael Michaelides, Pietro Paolo Sanna, Leandro F Vendruscolo
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Research square (2023)
Mingliang Lin, Lisa M Eubanks, Nishant M Karadkhelkar, Steven Blake, Kim D Janda
Catalytic Antibody Blunts Carfentanil-Induced Respiratory Depression. ACS pharmacology & translational science 6 (5) (2023)
Lucy Lin, Ealin N Patel, Alexander L Nielsen, Lewis D Turner, William H Tepp, Kong Nguyen, Sabine Pellett, Kim D Janda
Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease. International journal of molecular sciences 24 (5) (2023)
Nishant M Karadkhelkar, Mingliang Lin, Lisa M Eubanks, Kim D Janda
Demystifying the Druggability of the MYC Family of Oncogenes. Journal of the American Chemical Society 145 (6) (2023)
Jinny Claire Lee, Hyeri Park, Lisa M Eubanks, Beverly Ellis, Bin Zhou, Kim D Janda
A Vaccine against Benzimidazole-Derived New Psychoactive Substances That Are More Potent Than Fentanyl. Journal of medicinal chemistry 65 (3) (2022)
Ealin N Patel, Lucy Lin, Molly M Sneller, Lisa M Eubanks, William H Tepp, Sabine Pellett, Kim D Janda
Investigation of Salicylanilides as Botulinum Toxin Antagonists. ACS infectious diseases 8 (8) (2022)
Mingliang Lin, Alexander Marin, Beverly Ellis, Lisa M Eubanks, Alexander K Andrianov, Kim D Janda
Polyphosphazene: A New Adjuvant Platform for Cocaine Vaccine Development. Molecular pharmaceutics 19 (9) (2022)
Jinny Claire Lee, Lisa M Eubanks, Bin Zhou, Kim D Janda
Development of an Effective Monoclonal Antibody against Heroin and Its Metabolites Reveals Therapies Have Mistargeted 6-Monoacetylmorphine and Morphine over Heroin. ACS central science 8 (10) (2022)
Ealin N Patel, Lewis D Turner, Mark S Hixon, Kim D Janda
Identification of Slow-Binding Inhibitors of the BoNT/A Protease. ACS medicinal chemistry letters 13 (4) (2022)
Lewis D Turner, Alexander L Nielsen, Lucy Lin, Sabine Pellett, Takashi Sugane, Margaret E Olson, Eric A Johnson, Kim D Janda
Irreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach. RSC medicinal chemistry 12 (6) (2021)
Mingliang Lin, Beverly Ellis, Lisa M Eubanks, Kim D Janda
Pharmacokinetic Approach to Combat the Synthetic Cannabinoid PB-22. ACS chemical neuroscience 12 (14) (2021)
Margarita A Tararina, Katie K Dam, Manaswni Dhingra, Kim D Janda, Bruce A Palfey, Karen N Allen
Fast Kinetics Reveals Rate-Limiting Oxidation and the Role of the Aromatic Cage in the Mechanism of the Nicotine-Degrading Enzyme NicA2. Biochemistry 60 (4) (2021)
Josep Rayo, Rachel Gregor, Nicholas T Jacob, Rambabu Dandela, Luba Dubinsky, Alex Yashkin, Alexander Aranovich, Manikandan Thangaraj, Orna Ernst, Eran Barash, Sergey Malitsky, Bogdan I Florea, Bastiaan P Krom, Erik A C Wiemer, Valerie A Kickhoefer, Leonard H Rome, John C Mathison, Gunnar F Kaufmann, Herman S Overkleeft, Benjamin F Cravatt, Tsaffrir Zor, Kim D Janda, Richard J Ulevitch, Vladimir V Kravchenko, Michael M Meijler
Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones. Proceedings of the National Academy of Sciences of the United States of America 118 (12) (2021)
Lisa M Eubanks, Steven Blake, Yoshihiro Natori, Beverly Ellis, Paul T Bremer, Kim D Janda
A Highly Efficacious Carfentanil Vaccine That Blunts Opioid-Induced Antinociception and Respiratory Depression. ACS chemical biology 16 (2) (2021)
Lewis D Turner, Alexander L Nielsen, Lucy Lin, Antonio J Campedelli, Nicholas R Silvaggi, Jason S Chen, Amanda E Wakefield, Karen N Allen, Kim D Janda
Use of Crystallography and Molecular Modeling for the Inhibition of the Botulinum Neurotoxin A Protease. ACS medicinal chemistry letters 12 (8) (2021)
Steven Blake, Namir Shaabani, Lisa M Eubanks, Junki Maruyama, John T Manning, Nathan Beutler, Slobodan Paessler, Henry Ji, John R Teijaro, Kim D Janda
Salicylanilides Reduce SARS-CoV-2 Replication and Suppress Induction of Inflammatory Cytokines in a Rodent Model. ACS infectious diseases 7 (8) (2021)
Lucy Lin, Margaret E Olson, Takashi Sugane, Lewis D Turner, Margarita A Tararina, Alexander L Nielsen, Elbek K Kurbanov, Sabine Pellett, Eric A Johnson, Seth M Cohen, Karen N Allen, Kim D Janda
Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A. Journal of medicinal chemistry 63 (19) (2020)
Jinny Claire Lee, Kim D Janda
Immunopharmacotherapeutic advancements in addressing methamphetamine abuse. RSC chemical biology 2 (1) (2020)
Mingliang Lin, Jinny Claire Lee, Steven Blake, Beverly Ellis, Lisa M Eubanks, Kim D Janda
Broadly Neutralizing Synthetic Cannabinoid Vaccines. JACS Au 1 (1) (2020)
E Andrew Townsend, Paul T Bremer, Kaycee E Faunce, S Stevens Negus, Alaina M Jaster, Hannah L Robinson, Kim D Janda, Matthew L Banks
Evaluation of a Dual Fentanyl/Heroin Vaccine on the Antinociceptive and Reinforcing Effects of a Fentanyl/Heroin Mixture in Male and Female Rats. ACS chemical neuroscience 11 (9) (2020)
Steven Blake, Rajani Thanissery, Alissa J Rivera, Mark S Hixon, Mingliang Lin, Casey M Theriot, Kim D Janda
Salicylanilide Analog Minimizes Relapse of Clostridioides difficile Infection in Mice. Journal of medicinal chemistry 63 (13) (2020)
Steven Blake, Paul T Bremer, Bin Zhou, Nikolai Petrovsky, Lauren C Smith, Candy S Hwang, Kim D Janda
Developing Translational Vaccines against Heroin and Fentanyl through Investigation of Adjuvants and Stability. Molecular pharmaceutics 18 (1) (2020)
Lucy Lin, Lewis D Turner, Peter Šilhár, Sabine Pellett, Eric A Johnson, Kim D Janda
Identification of 3-hydroxy-1,2-dimethylpyridine-4(1H)-thione as a metal-binding motif for the inhibition of botulinum neurotoxin A. RSC medicinal chemistry 12 (1) (2020)
Tyson F Belz, Paul T Bremer, Bin Zhou, Beverly Ellis, Lisa M Eubanks, Kim D Janda
Enhancement of a Heroin Vaccine through Hapten Deuteration. Journal of the American Chemical Society 142 (31) (2020)
Lucy Lin, Margaret E Olson, Lisa M Eubanks, Kim D Janda
Strategies to Counteract Botulinum Neurotoxin A: Nature's Deadliest Biomolecule. Accounts of chemical research 52 (8) (2019)
Yoshihiro Natori, Candy S Hwang, Lucy Lin, Lauren C Smith, Bin Zhou, Kim D Janda
A chemically contiguous hapten approach for a heroin-fentanyl vaccine. Beilstein journal of organic chemistry 15 (2019)
Margaret E Olson, Takashi Sugane, Bin Zhou, Kim D Janda
Consequence of Hapten Stereochemistry: An Efficacious Methamphetamine Vaccine. Journal of the American Chemical Society 141 (36) (2019)
Lauren C Smith, Paul T Bremer, Candy S Hwang, Bin Zhou, Beverly Ellis, Mark S Hixon, Kim D Janda
Monoclonal Antibodies for Combating Synthetic Opioid Intoxication. Journal of the American Chemical Society 141 (26) (2019)
Ryan J Shirey, Daniel Globisch, Lisa M Eubanks, Mark S Hixon, Kim D Janda
Noninvasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis. ACS infectious diseases 4 (10) (2018)
Lauren C Smith, Lucy Lin, Candy S Hwang, Bin Zhou, Diane M Kubitz, Huiying Wang, Kim D Janda
Lateral Flow Assessment and Unanticipated Toxicity of Kratom. Chemical research in toxicology 32 (1) (2018)
Margaret E Olson, Lisa M Eubanks, Kim D Janda
Chemical Interventions for the Opioid Crisis: Key Advances and Remaining Challenges. Journal of the American Chemical Society 141 (5) (2018)
Margarita A Tararina, Song Xue, Lauren C Smith, Samantha N Muellers, Pedro O Miranda, Kim D Janda, Karen N Allen
Crystallography Coupled with Kinetic Analysis Provides Mechanistic Underpinnings of a Nicotine-Degrading Enzyme. Biochemistry 57 (26) (2018)
Candy S Hwang, Lauren C Smith, Yoshihiro Natori, Beverly Ellis, Bin Zhou, Kim D Janda
Efficacious Vaccine against Heroin Contaminated with Fentanyl. ACS chemical neuroscience 9 (6) (2018)
Pedro O Miranda, Beatrice Cubitt, Nicholas T Jacob, Kim D Janda, Juan C de la Torre
Mining a Kröhnke Pyridine Library for Anti-Arenavirus Activity. ACS infectious diseases 4 (5) (2018)
Candy S Hwang, Paul T Bremer, Cody J Wenthur, Sam On Ho, SuMing Chiang, Beverly Ellis, Bin Zhou, Gary Fujii, Kim D Janda
Enhancing Efficacy and Stability of an Antiheroin Vaccine: Examination of Antinociception, Opioid Binding Profile, and Lethality. Molecular pharmaceutics 15 (3) (2018)
Paul T Bremer, Michael Adler, Cecilia H Phung, Ajay K Singh, Kim D Janda
Newly Designed Quinolinol Inhibitors Mitigate the Effects of Botulinum Neurotoxin A in Enzymatic, Cell-Based, and ex Vivo Assays. Journal of medicinal chemistry 60 (1) (2017)
Paul T Bremer, Joel E Schlosburg, Matthew L Banks, Floyd F Steele, Bin Zhou, Justin L Poklis, Kim D Janda
Development of a Clinically Viable Heroin Vaccine. Journal of the American Chemical Society 139 (25) (2017)
Candy S Hwang, Kim D Janda
A Vision for Vaccines: Combating the Opioid Epidemic. Biochemistry 56 (42) (2017)
Paul T Bremer, Sabine Pellett, James P Carolan, William H Tepp, Lisa M Eubanks, Karen N Allen, Eric A Johnson, Kim D Janda
Metal Ions Effectively Ablate the Action of Botulinum Neurotoxin A. Journal of the American Chemical Society 139 (21) (2017)
Atsushi Kimishima, Cody J Wenthur, Bin Zhou, Kim D Janda
An Advance in Prescription Opioid Vaccines: Overdose Mortality Reduction and Extraordinary Alteration of Drug Half-Life. ACS chemical biology 12 (1) (2016)
Major Gooyit, Pedro O Miranda, Cody J Wenthur, Alex Ducime, Kim D Janda
Influencing Antibody-Mediated Attenuation of Methamphetamine CNS Distribution through Vaccine Linker Design. ACS chemical neuroscience 8 (3) (2016)