Alexander K Buell (A K Buell, Alexander Buell)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 47

Top Venues

Nature communications

Physical chemistry chemical physics : PCCP

Chemical science

BMC biology

Heinrich-Heine-Universitat Düsseldorf

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Heinrich-Heine-Universitat Düsseldorf Oct 01 2015 - Mar 31 2019

Germany

W1 Professor of Physical Biology :: Biology

Publications

Sarah G Heath, Shelby G Gray, Emilie M Hamzah, Karina M O'Connor, Stephanie M Bozonet, Alex D Botha, Pierre de Cordovez, Nicholas J Magon, Jennifer D Naughton, Dylan L W Goldsmith, Abigail J Schwartfeger, Margaret Sunde, Alexander K Buell, Vanessa K Morris, Christoph Göbl
Amyloid formation and depolymerization of tumor suppressor p16 INK4a are regulated by a thiol-dependent redox mechanism. Nature communications 15 (1) (2024)
Rasmus Krogh Norrild, Thomas O Mason, Lars Boyens-Thiele, Soumik Ray, Joachim B Mortensen, Anatol W Fritsch, Juan M Iglesias-Artola, Louise K Klausen, Emil G P Stender, Henrik Jensen, Alexander K Buell
Taylor Dispersion-Induced Phase Separation for the Efficient Characterisation of Protein Condensate Formation. Angewandte Chemie (International ed. in English) 63 (25) (2024)
Azad Farzadfard, Antonin Kunka, Thomas Oliver Mason, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Elisa Torrescasana Dominguez, Soumik Ray, Alexander K Buell
Thermodynamic characterization of amyloid polymorphism by microfluidic transient incomplete separation. Chemical science 15 (7) (2024)
Rasmus Krogh Norrild, Thomas O Mason, Lars Boyens-Thiele, Soumik Ray, Joachim B Mortensen, Anatol W Fritsch, Juan M Iglesias-Artola, Louise K Klausen, Emil G P Stender, Henrik Jensen, Alexander K Buell
Taylor Dispersion-Induced Phase Separation for the Efficient Characterisation of Protein Condensate Formation. Angewandte Chemie (International ed. in English) 63 (25) (2024)
Rasmus Krogh Norrild, Thomas O Mason, Lars Boyens-Thiele, Soumik Ray, Joachim B Mortensen, Anatol W Fritsch, Juan M Iglesias-Artola, Louise K Klausen, Emil G P Stender, Henrik Jensen, Alexander K Buell
Taylor Dispersion-Induced Phase Separation for the Efficient Characterisation of Protein Condensate Formation. Angewandte Chemie (International ed. in English) (2024)
Sarah G Heath, Shelby G Gray, Emilie M Hamzah, Karina M O'Connor, Stephanie M Bozonet, Alex D Botha, Pierre de Cordovez, Nicholas J Magon, Jennifer D Naughton, Dylan L W Goldsmith, Abigail J Schwartfeger, Margaret Sunde, Alexander K Buell, Vanessa K Morris, Christoph Göbl
Amyloid formation and depolymerization of tumor suppressor p16 INK4a are regulated by a thiol-dependent redox mechanism. Nature communications 15 (1) (2024)
Soumik Ray, Alexander K Buell
Emerging experimental methods to study the thermodynamics of biomolecular condensate formation. The Journal of chemical physics 160 (9) (2024)
Céline Galvagnion, Abigail Barclay, Katarzyna Makasewicz, Frederik Ravnkilde Marlet, Martine Moulin, Juliette M Devos, Sara Linse, Anne Martel, Lionel Porcar, Emma Sparr, Martin Cramer Pedersen, Felix Roosen-Runge, Lise Arleth, Alexander K Buell
Structural characterisation of α-synuclein-membrane interactions and the resulting aggregation using small angle scattering. Physical chemistry chemical physics : PCCP (2024)
Sarah G Heath, Shelby G Gray, Emilie M Hamzah, Karina M O'Connor, Stephanie M Bozonet, Alex D Botha, Pierre de Cordovez, Nicholas J Magon, Jennifer D Naughton, Dylan L W Goldsmith, Abigail J Schwartfeger, Margaret Sunde, Alexander K Buell, Vanessa K Morris, Christoph Göbl
Amyloid formation and depolymerization of tumor suppressor p16 INK4a are regulated by a thiol-dependent redox mechanism. Nature communications 15 (1) (2024)
Céline Galvagnion, Abigail Barclay, Katarzyna Makasewicz, Frederik Ravnkilde Marlet, Martine Moulin, Juliette M Devos, Sara Linse, Anne Martel, Lionel Porcar, Emma Sparr, Martin Cramer Pedersen, Felix Roosen-Runge, Lise Arleth, Alexander K Buell
Structural characterisation of α-synuclein-membrane interactions and the resulting aggregation using small angle scattering. Physical chemistry chemical physics : PCCP 26 (14) (2024)
Sarah G Heath, Shelby G Gray, Emilie M Hamzah, Karina M O'Connor, Stephanie M Bozonet, Alex D Botha, Pierre de Cordovez, Nicholas J Magon, Jennifer D Naughton, Dylan L W Goldsmith, Abigail J Schwartfeger, Margaret Sunde, Alexander K Buell, Vanessa K Morris, Christoph Göbl
Amyloid formation and depolymerization of tumor suppressor p16 INK4a are regulated by a thiol-dependent redox mechanism. Nature communications 15 (1) (2024)
Céline Galvagnion, Abigail Barclay, Katarzyna Makasewicz, Frederik Ravnkilde Marlet, Martine Moulin, Juliette M Devos, Sara Linse, Anne Martel, Lionel Porcar, Emma Sparr, Martin Cramer Pedersen, Felix Roosen-Runge, Lise Arleth, Alexander K Buell
Structural characterisation of α-synuclein-membrane interactions and the resulting aggregation using small angle scattering. Physical chemistry chemical physics : PCCP 26 (14) (2024)
Céline Galvagnion, Abigail Barclay, Katarzyna Makasewicz, Frederik Ravnkilde Marlet, Martine Moulin, Juliette M Devos, Sara Linse, Anne Martel, Lionel Porcar, Emma Sparr, Martin Cramer Pedersen, Felix Roosen-Runge, Lise Arleth, Alexander K Buell
Structural characterisation of α-synuclein-membrane interactions and the resulting aggregation using small angle scattering. Physical chemistry chemical physics : PCCP 26 (14) (2024)
Azad Farzadfard, Antonin Kunka, Thomas Oliver Mason, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Elisa Torrescasana Dominguez, Soumik Ray, Alexander K Buell
Thermodynamic characterization of amyloid polymorphism by microfluidic transient incomplete separation. Chemical science 15 (7) (2024)
Rebecca Sternke-Hoffmann, Thomas Pauly, Rasmus K Norrild, Jan Hansen, Florian Tucholski, Magnus Haraldson Høie, Paolo Marcatili, Mathieu Dupré, Magalie Duchateau, Martial Rey, Christian Malosse, Sabine Metzger, Amelie Boquoi, Florian Platten, Stefan U Egelhaaf, Julia Chamot-Rooke, Roland Fenk, Luitgard Nagel-Steger, Rainer Haas, Alexander K Buell
Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains. BMC biology 21 (1) (2023)
Rebecca Sternke-Hoffmann, Thomas Pauly, Rasmus K Norrild, Jan Hansen, Florian Tucholski, Magnus Haraldson Høie, Paolo Marcatili, Mathieu Dupré, Magalie Duchateau, Martial Rey, Christian Malosse, Sabine Metzger, Amelie Boquoi, Florian Platten, Stefan U Egelhaaf, Julia Chamot-Rooke, Roland Fenk, Luitgard Nagel-Steger, Rainer Haas, Alexander K Buell
Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains. BMC biology 21 (1) (2023)
Soumav Nath, Alexander K Buell, Bogdan Barz
Pyroglutamate-modified amyloid β(3-42) monomer has more β-sheet content than the amyloid β(1-42) monomer. Physical chemistry chemical physics : PCCP (2023)
Andreas V Madsen, Peter Kristensen, Alexander K Buell, Steffen Goletz
Generation of robust bispecific antibodies through fusion of single-domain antibodies on IgG scaffolds: a comprehensive comparison of formats. mAbs 15 (1) (2023)
Rebecca Sternke-Hoffmann, Thomas Pauly, Rasmus K Norrild, Jan Hansen, Florian Tucholski, Magnus Haraldson Høie, Paolo Marcatili, Mathieu Dupré, Magalie Duchateau, Martial Rey, Christian Malosse, Sabine Metzger, Amelie Boquoi, Florian Platten, Stefan U Egelhaaf, Julia Chamot-Rooke, Roland Fenk, Luitgard Nagel-Steger, Rainer Haas, Alexander K Buell
Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains. BMC biology 21 (1) (2023)
Andreas V Madsen, Peter Kristensen, Alexander K Buell, Steffen Goletz
Generation of robust bispecific antibodies through fusion of single-domain antibodies on IgG scaffolds: a comprehensive comparison of formats. mAbs 15 (1) (2023)
Rebecca Sternke-Hoffmann, Thomas Pauly, Rasmus K Norrild, Jan Hansen, Florian Tucholski, Magnus Haraldson Høie, Paolo Marcatili, Mathieu Dupré, Magalie Duchateau, Martial Rey, Christian Malosse, Sabine Metzger, Amelie Boquoi, Florian Platten, Stefan U Egelhaaf, Julia Chamot-Rooke, Roland Fenk, Luitgard Nagel-Steger, Rainer Haas, Alexander K Buell
Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains. BMC biology 21 (1) (2023)
Soumik Ray, Thomas O Mason, Lars Boyens-Thiele, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Nadin Jahnke, Alexander K Buell
Mass photometric detection and quantification of nanoscale α-synuclein phase separation. Nature chemistry (2023)
Vivian Lorena Leguizamon Herrera, Alexander K Buell, Dieter Willbold, Bogdan Barz
Interaction of Therapeutic d-Peptides with Aβ42 Monomers, Thermodynamics, and Binding Analysis. ACS chemical neuroscience 13 (11) (2022)
Duo Zhang, Yaqi Sheng, Nicholas Piano, Theresa Jakuszeit, Edward Jonathan Cozens, Lingqing Dong, Alexander K Buell, Andreas M A O Pollet, Iek Man Lei, Wenyu Wang, Eugene Michael Terentjev, Yan Yan Shery Huang
Cancer cell migration on straight, wavy, loop and grid microfibre patterns. Biofabrication 14 (2) (2022)
Jasmin Bartl, Marco Zanini, Flavia Bernardi, Antoine Forget, Lena Blümel, Julie Talbot, Daniel Picard, Nan Qin, Gabriele Cancila, Qingsong Gao, Soumav Nath, Idriss Mahoungou Koumba, Marietta Wolter, François Kuonen, Maike Langini, Thomas Beez, Christopher Munoz, David Pauck, Viktoria Marquardt, Hua Yu, Judith Souphron, Mascha Korsch, Christina Mölders, Daniel Berger, Sarah Göbbels, Frauke-Dorothee Meyer, Björn Scheffler, Barak Rotblat, Sven Diederichs, Vijay Ramsawami, Hiromichi Suzuki, Anthony E Oro, Kai Stühler, Anja Stefanski, Ute Fischer, Gabriel Leprivier, Dieter Willbold, Gerhard Steger, Alexander K Buell, Marcel Kool, Peter Lichter, Stefan M Pfister, Paul A Northcott, Michael D Taylor, Arndt Borkhardt, Guido Reifenberger, Olivier Ayrault, Marc Remke
The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors. Nature communications 13 (1) (2022)
Alexander K Buell
Stability matters, too - the thermodynamics of amyloid fibril formation. Chemical science 13 (35) (2022)
Hossein Mohammad-Beigi, Masumeh Zanganeh, Carsten Scavenius, Hoda Eskandari, Azad Farzadfard, Seyed Abbas Shojaosadati, Jan J Enghild, Daniel Erik Otzen, Alexander K Buell, Duncan S Sutherland
A Protein Corona Modulates Interactions of α-Synuclein with Nanoparticles and Alters the Rates of the Microscopic Steps of Amyloid Formation. ACS nano 16 (1) (2022)
Mathieu Dupré, Magalie Duchateau, Rebecca Sternke-Hoffmann, Amelie Boquoi, Christian Malosse, Roland Fenk, Rainer Haas, Alexander K Buell, Martial Rey, Julia Chamot-Rooke
De Novo Sequencing of Antibody Light Chain Proteoforms from Patients with Multiple Myeloma. Analytical chemistry 93 (30) (2021)
Bogdan Barz, Alexander K Buell, Soumav Nath
Compact fibril-like structure of amyloid β-peptide (1-42) monomers. Chemical communications (Cambridge, England) 57 (7) (2021)
Emil G P Stender, Soumik Ray, Rasmus Krogh Norrild, Jacob Aunstrup Larsen, Daniel Petersen, Azad Farzadfard, Céline Galvagnion, Henrik Jensen, Alexander K Buell
Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation. Nature communications 12 (1) (2021)
Blanca Lopez Mendez, Bruno Baron, Chad A Brautigam, Thomas A Jowitt, Stefan H Knauer, Stephan Uebel, Mark A Williams, Arthur Sedivy, Olga Abián, Celeste Abreu, Malgorzata Adamczyk, Wojciech Bal, Sylvie Berger, Alexander K Buell, Carlo Carolis, Tina Daviter, Alexander Fish, Maria M Garcia Alai, Christian Guenther, Josef Hamacek, Jitka Holková, Josef Houser, Chris Johnson, Sharon Kelly, Andrew Leech, Caroline Mas, Daumantas Matulis, Stephen H McLaughlin, Roland Montserret, Rouba Nasreddine, Reine Nehmé, Quyen Nguyen, David Ortega-Alarcón, Kathryn Perez, Katja Pirc, Grzegorz Piszczek, Marjetka Podobnik, Natalia Rodrigo, Jasmina Rokov-Plavec, Susanne Schaefer, Tim Sharpe, June Southall, David Staunton, Pedro Tavares, Ondřej Vaněk, Michael Weyand, Di Wu
Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study. European biophysics journal : EBJ 50 (3-4) (2021)
Soumav Nath, Priti Roy, Raki Mandal, Rajat Roy, Alexander K Buell, Neelanjana Sengupta, Pradip K Tarafdar
Hydroxy-Porphyrin as an Effective, Endogenous Molecular Clamp during Early Stages of Amyloid Fibrillization. Chemistry, an Asian journal 16 (23) (2021)
Juami Hermine Mariama van Gils, Erik van Dijk, Alessia Peduzzo, Alexander Hofmann, Nicola Vettore, Marie P Schützmann, Georg Groth, Halima Mouhib, Daniel Erik Otzen, Alexander K Buell, Sanne Abeln
The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth. PLoS computational biology 16 (5) (2020)
Alessia Peduzzo, Sara Linse, Alexander K Buell
The Properties of α-Synuclein Secondary Nuclei Are Dominated by the Solution Conditions Rather than the Seed Fibril Strain. ACS chemical neuroscience 11 (6) (2020)
Rebecca Sternke-Hoffmann, Alessia Peduzzo, Najoua Bolakhrif, Rainer Haas, Alexander K Buell
The Aggregation Conditions Define Whether EGCG is an Inhibitor or Enhancer of α-Synuclein Amyloid Fibril Formation. International journal of molecular sciences 21 (6) (2020)
Tomas Šneideris, Andrius Sakalauskas, Rebecca Sternke-Hoffmann, Alessia Peduzzo, Mantas Ziaunys, Alexander K Buell, Vytautas Smirnovas
The Environment Is a Key Factor in Determining the Anti-Amyloid Efficacy of EGCG. Biomolecules 9 (12) (2019)
Christine Röder, Nicola Vettore, Lena N Mangels, Lothar Gremer, Raimond B G Ravelli, Dieter Willbold, Wolfgang Hoyer, Alexander K Buell, Gunnar F Schröder
Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy. Nature communications 10 (1) (2019)
Céline Galvagnion, Daniel Topgaard, Katarzyna Makasewicz, Alexander K Buell, Sara Linse, Emma Sparr, Christopher M Dobson
Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils. The journal of physical chemistry letters 10 (24) (2019)
Emil Dandanell Agerschou, Patrick Flagmeier, Theodora Saridaki, Céline Galvagnion, Daniel Komnig, Laetitia Heid, Vibha Prasad, Hamed Shaykhalishahi, Dieter Willbold, Christopher M Dobson, Aaron Voigt, Björn H Falkenburger, Wolfgang Hoyer, Alexander K Buell
An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils. eLife 8 (2019)
Hongze Gang, Céline Galvagnion, Georg Meisl, Thomas Müller, Manuela Pfammatter, Alexander K Buell, Aviad Levin, Christopher M Dobson, Bozhong Mu, Tuomas P J Knowles
Microfluidic Diffusion Platform for Characterizing the Sizes of Lipid Vesicles and the Thermodynamics of Protein-Lipid Interactions. Analytical chemistry 90 (5) (2018)
Ingrid M van der Wateren, Tuomas P J Knowles, Alexander K Buell, Christopher M Dobson, Céline Galvagnion
C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH. Chemical science 9 (25) (2018)
James W P Brown, Georg Meisl, Tuomas P J Knowles, Alexander K Buell, Christopher M Dobson, Céline Galvagnion
Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils. Chemical communications (Cambridge, England) 54 (56) (2018)
Thibault Viennet, Michael M Wördehoff, Boran Uluca, Chetan S Poojari, Hamed Shaykhalishahi, Dieter Willbold, Birgit Strodel, Henrike Heise, Alexander K Buell, Wolfgang Hoyer, Manuel Etzkorn
Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation. Communications biology 1 (2018)
Tamar Ziehm, Alexander K Buell, Dieter Willbold
Role of Hydrophobicity and Charge of Amyloid-Beta Oligomer Eliminating d-Peptides in the Interaction with Amyloid-Beta Monomers. ACS chemical neuroscience 9 (11) (2018)
C Dammers, Melanie Schwarten, Alexander K Buell, Dieter Willbold
Pyroglutamate-modified Aβ(3-42) affects aggregation kinetics of Aβ(1-42) by accelerating primary and secondary pathways. Chemical science 8 (7) (2017)
Emily Fisher, Yanyan Zhao, Robert Richardson, Malgorzata Janik, Alexander K Buell, Franklin I Aigbirhio, Gergely Tóth
Detection and Characterization of Small Molecule Interactions with Fibrillar Protein Aggregates Using Microscale Thermophoresis. ACS chemical neuroscience 8 (9) (2017)
Thomas O Mason, Thomas C T Michaels, Aviad Levin, Christopher M Dobson, Ehud Gazit, Tuomas P J Knowles, Alexander K Buell
Thermodynamics of Polypeptide Supramolecular Assembly in the Short-Chain Limit. Journal of the American Chemical Society 139 (45) (2017)

Alexander K Buell.css-eqlu8i{font-size:small;padding-left:4px;} (A K Buell, Alexander Buell)

Publication Activity (10 Years)

Top Topics

Top Venues

Alexander K Buell (A K Buell, Alexander Buell)