Dennis W Wolan

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 31

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

ACS chemical biology

Journal of proteome research

Nature chemical biology

The Scripps Research Institute

The Scripps Research Institute (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The Scripps Research Institute

United States

Associate Professor :: Molecular Medicine

The Scripps Research Institute

United States

Assistant Professor :: Molecular and Experimental Medicine

University of California San Francisco

United States

Postdoctoral Fellow :: Pharmaceutical Chemistry and Small Molecule Discovery Center

Sunesis Pharmaceuticals, Inc.

United States

Postdoctoral Fellow

The Scripps Research Institute

United States

Postdoctoral Fellow :: The Skaggs Institute for Chemical Biology and Joint Center for Structural Genomics

The Scripps Research Institute

United States

Graduate Student :: Molecular Biology

Cleveland Clinic Lerner Research Institute

United States

Research Technician :: Immunology

Education History

The Scripps Research Institute

United States

PHD :: Molecular Biology

Bowling Green State University

United States

BSC :: Chemistry

Publications

Seiya Kitamura, Ting-Hui Lin, Chang-Chun David Lee, Akihiro Takamura, Rameshwar U Kadam, Ding Zhang, Xueyong Zhu, Lucas Dada, Emiko Nagai, Wenli Yu, Yao Yao, K Barry Sharpless, Ian A Wilson, Dennis W Wolan
Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Seiya Kitamura, Ting-Hui Lin, Chang-Chun David Lee, Akihiro Takamura, Rameshwar U Kadam, Ding Zhang, Xueyong Zhu, Lucas Dada, Emiko Nagai, Wenli Yu, Yao Yao, K Barry Sharpless, Ian A Wilson, Dennis W Wolan
Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Seiya Kitamura, Ting-Hui Lin, Chang-Chun David Lee, Akihiro Takamura, Rameshwar U Kadam, Ding Zhang, Xueyong Zhu, Lucas Dada, Emiko Nagai, Wenli Yu, Yao Yao, K Barry Sharpless, Ian A Wilson, Dennis W Wolan
Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Seiya Kitamura, Ting-Hui Lin, Chang-Chun David Lee, Akihiro Takamura, Rameshwar U Kadam, Ding Zhang, Xueyong Zhu, Lucas Dada, Emiko Nagai, Wenli Yu, Yao Yao, K Barry Sharpless, Ian A Wilson, Dennis W Wolan
Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Seiya Kitamura, Ting-Hui Lin, Chang-Chun David Lee, Akihiro Takamura, Rameshwar U Kadam, Ding Zhang, Xueyong Zhu, Lucas Dada, Emiko Nagai, Wenli Yu, Yao Yao, K Barry Sharpless, Ian A Wilson, Dennis W Wolan
Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proceedings of the National Academy of Sciences of the United States of America 121 (22) (2024)
Cristina Porras-Alcalá, Federico Moya-Utrera, Miguel García-Castro, Antonio Sánchez-Ruiz, Juan Manuel López-Romero, María Soledad Pino-González, Amelia Díaz-Morilla, Seiya Kitamura, Dennis W Wolan, Jose Carlos Prados, Consolación Melguizo, Iván Cheng-Sánchez, Francisco Sarabia
The Development of the Bengamides as New Antibiotics against Drug-Resistant Bacteria. Marine drugs 20 (6) (2022)
Yunfei Cheng, Gencheng Li, Christopher J Smedley, Marie-Claire Giel, Seiya Kitamura, Jordan L Woehl, Giulia Bianco, Stefano Forli, Joshua A Homer, John R Cappiello, Dennis W Wolan, John E Moses, K Barry Sharpless
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors. Proceedings of the National Academy of Sciences of the United States of America 119 (37) (2022)
Leopold Garnar-Wortzel, Timothy R Bishop, Seiya Kitamura, Natalia Milosevich, Joshua N Asiaban, Xiaoyu Zhang, Qinheng Zheng, Emily Chen, Anissa R Ramos, Christopher J Ackerman, Eric N Hampton, Arnab K Chatterjee, Travis S Young, Mitchell V Hull, K Barry Sharpless, Benjamin F Cravatt, Dennis W Wolan, Michael A Erb
Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia. ACS central science 7 (5) (2021)
J Rafael Montenegro-Burke, Bernard P Kok, Carlos Guijas, Xavier Domingo-Almenara, Clara Moon, Andrea Galmozzi, Seiya Kitamura, Lars Eckmann, Enrique Saez, Gary E Siuzdak, Dennis W Wolan
Metabolomics activity screening of T cell-induced colitis reveals anti-inflammatory metabolites. Science signaling 14 (702) (2021)
Peter S Thuy-Boun, Subina Mehta, Bjoern Andreas Gruening, Thomas McGowan, An Nguyen, Andrew T Rajczewski, James E Johnson, Timothy J Griffin, Dennis W Wolan, Pratik D Jagtap
Metaproteomics Analysis of SARS-CoV-2-Infected Patient Samples Reveals Presence of Potential Coinfecting Microorganisms. Journal of proteome research 20 (2) (2021)
Michael C Yoon, Angelo Solania, Zhenze Jiang, Mitchell P Christy, Sonia Podvin, Charles Mosier, Christopher B Lietz, Gen Ito, William H Gerwick, Dennis W Wolan, Gregory Hook, Anthony J O'Donoghue, Vivian Hook
Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions. ACS chemical biology 16 (9) (2021)
Jordan L Woehl, Seiya Kitamura, Nicholas Dillon, Zhen Han, Landon J Edgar, Victor Nizet, Dennis W Wolan
An Irreversible Inhibitor to Probe the Role of Streptococcus pyogenes Cysteine Protease SpeB in Evasion of Host Complement Defenses. ACS chemical biology 15 (8) (2020)
Emily N Chin, Chenguang Yu, Vincent F Vartabedian, Ying Jia, Manoj Kumar, Ana M Gamo, William Vernier, Sabrina H Ali, Mildred Kissai, Daniel C Lazar, Nhan Nguyen, Laura E Pereira, Brent Benish, Ashley K Woods, Sean B Joseph, Alan Chu, Kristen A Johnson, Philipp N Sander, Francisco Martínez-Peña, Eric N Hampton, Travis S Young, Dennis W Wolan, Arnab K Chatterjee, Peter G Schultz, H Michael Petrassi, John R Teijaro, Luke L Lairson
Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science (New York, N.Y.) 369 (6506) (2020)
Seiya Kitamura, Qinheng Zheng, Jordan L Woehl, Angelo Solania, Emily Chen, Nicholas Dillon, Mitchell V Hull, Miyako Kotaniguchi, John R Cappiello, Shinichi Kitamura, Victor Nizet, K Barry Sharpless, Dennis W Wolan
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry. Journal of the American Chemical Society 142 (25) (2020)
Bernard P Kok, Srijana Ghimire, Woojoo E Kim, Shreyosree Chatterjee, Tyler Johns, Seiya Kitamura, Jerome Eberhardt, Daisuke Ogasawara, Janice H Xu, Ara Sukiasyan, Sean M Kim, Cristina Godio, Julia M Bittencourt, Michael D Cameron, Andrea Galmozzi, Stefano Forli, Dennis W Wolan, Benjamin F Cravatt, Dale L Boger, Enrique Saez
Discovery of small-molecule enzyme activators by activity-based protein profiling. Nature chemical biology 16 (9) (2020)
Yao Yao, Rameshwar U Kadam, Chang-Chun David Lee, Jordan L Woehl, Nicholas C Wu, Xueyong Zhu, Seiya Kitamura, Ian A Wilson, Dennis W Wolan
An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen. Proceedings of the National Academy of Sciences of the United States of America 117 (31) (2020)
Janice H Xu, Jerome Eberhardt, Brianna Hill-Payne, Gonzalo E González-Páez, José Omar Castellón, Benjamin F Cravatt, Stefano Forli, Dennis W Wolan, Keriann M Backus
Integrative X-ray Structure and Molecular Modeling for the Rationalization of Procaspase-8 Inhibitor Potency and Selectivity. ACS chemical biology 15 (2) (2020)
Qinheng Zheng, Jordan L Woehl, Seiya Kitamura, Diogo Santos-Martins, Christopher J Smedley, Gencheng Li, Stefano Forli, John E Moses, Dennis W Wolan, K Barry Sharpless
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proceedings of the National Academy of Sciences of the United States of America 116 (38) (2019)
Elizabeth N Bess, Jordan E Bisanz, Fauna Yarza, Annamarie E Bustion, Barry E Rich, Xingnan Li, Seiya Kitamura, Emily Waligurski, Qi Yan Ang, Diana L Alba, Peter Spanogiannopoulos, Stephen Nayfach, Suneil K Koliwad, Dennis W Wolan, Adrian A Franke, Peter J Turnbaugh
Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria. Nature microbiology 5 (1) (2019)
Sung-Kyu Robin Park, Titus Jung, Peter S Thuy-Boun, Ana Y Wang, John Yates Iii, Dennis W Wolan
ComPIL 2.0: An Updated Comprehensive Metaproteomics Database. Journal of proteome research 18 (2) (2019)
Marilyn H Gordon, Anthonia Anowai, Daniel Young, Nabangshu Das, Rhiannon I Campden, Henna Sekhon, Zoe Myers, Barbara Mainoli, Sameeksha Chopra, Peter S Thuy-Boun, Jayachandran N Kizhakkedathu, Gurmeet Bindra, Humberto B Jijon, Steven Heitman, Robin Yates, Dennis W Wolan, Laura E Edgington-Mitchell, Wallace K MacNaughton, Antoine Dufour
N-Terminomics/TAILS Profiling of Proteases and Their Substrates in Ulcerative Colitis. ACS chemical biology 14 (11) (2019)
Emily J Roncase, Gonzalo E González-Páez, Dennis W Wolan
X-ray Structures of Two Bacteroides thetaiotaomicron C11 Proteases in Complex with Peptide-Based Inhibitors. Biochemistry 58 (13) (2019)
Angelo Solania, Gonzalo E González-Páez, Dennis W Wolan
Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3. ACS chemical biology 14 (11) (2019)
Eric W Deutsch, Yasset Perez Riverol, Robert J Chalkley, Mathias Wilhelm, Stephen Tate, Timo Sachsenberg, Mathias Walzer, Lukas Käll, Bernard Delanghe, Sebastian Böcker, Emma L Schymanski, Paul Wilmes, Viktoria Dorfer, Bernhard Kuster, Pieter-Jan Volders, Nico Jehmlich, Johannes P C Vissers, Dennis W Wolan, Ana Y Wang, Luis Mendoza, Jim Shofstahl, Andrew W Dowsey, Johannes Griss, Reza M Salek, Steffen Neumann, Pierre-Alain Binz, Henry H N Lam, Juan Antonio Vizcaino, Nuno Bandeira, Hannes L Röst
Expanding the Use of Spectral Libraries in Proteomics. Journal of proteome research 17 (12) (2018)
Seiya Kitamura, Dennis W Wolan
Probing substrate recognition of bacterial lipoprotein signal peptidase using FRET reporters. FEBS letters 592 (13) (2018)
Carlos Guijas, J Rafael Montenegro-Burke, Xavier Domingo-Almenara, Amelia Palermo, Benedikt Warth, Gerrit Hermann, Gunda Koellensperger, Tao Huan, Winnie Uritboonthai, Aries E Aisporna, Dennis W Wolan, Mary E Spilker, H Paul Benton, Gary E Siuzdak
METLIN: A Technology Platform for Identifying Knowns and Unknowns. Analytical chemistry 90 (5) (2018)
Janice H Xu, Zhenze Jiang, Angelo Solania, Sandip Chatterjee, Brian Suzuki, Christopher B Lietz, Vivian Y H Hook, Anthony J O'Donoghue, Dennis W Wolan
A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro. ACS chemical biology 13 (9) (2018)
Ana Y Wang, Peter S Thuy-Boun, Gregory S Stupp, Andrew I Su, Dennis W Wolan
Triflic Acid Treatment Enables LC-MS/MS Analysis of Insoluble Bacterial Biomass. Journal of proteome research 17 (9) (2018)
Emily P Balskus, Peter J Turnbaugh, Dennis W Wolan
Announcement of 2019 Keystone Symposia Conference: "Microbiome: Chemical Mechanisms and Biological Consequences". mSystems 3 (4) (2018)
Michael D Mayers, Clara Moon, Gregory S Stupp, Andrew I Su, Dennis W Wolan
Quantitative Metaproteomics and Activity-Based Probe Enrichment Reveals Significant Alterations in Protein Expression from a Mouse Model of Inflammatory Bowel Disease. Journal of proteome research 16 (2) (2017)
Emily J Roncase, Clara Moon, Sandip Chatterjee, Gonzalo E González-Páez, Charles S Craik, Anthony J O'Donoghue, Dennis W Wolan
Substrate Profiling and High Resolution Co-complex Crystal Structure of a Secreted C11 Protease Conserved across Commensal Bacteria. ACS chemical biology 12 (6) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Dennis W Wolan