Manuela Jörg

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 11

Top Topics

Molecular Docking

Binding Protein

Bipolar Disorder

Top Venues

Journal of medicinal chemistry

RSC medicinal chemistry

British journal of pharmacology

This page only lists publications with an associated author ORCID identifier.

Publications

Boqun Liu, Geoff Thompson, Manuela Jörg, Nicholas Barnes, David M Thal, Arthur Christopoulos, Ben Capuano, Celine Valant, Peter J Scammells
Discovery of 2-Methyl-5-(1 H -pyrazol-4-yl)pyridines and Related Heterocycles as Promising M 4 mAChR Positive Allosteric Modulators for the Treatment of Neurocognitive Disorders. Journal of medicinal chemistry 67 (15) (2024)
Boqun Liu, Geoff Thompson, Manuela Jörg, Nicholas Barnes, David M Thal, Arthur Christopoulos, Ben Capuano, Celine Valant, Peter J Scammells
Discovery of 2-Methyl-5-(1 H -pyrazol-4-yl)pyridines and Related Heterocycles as Promising M 4 mAChR Positive Allosteric Modulators for the Treatment of Neurocognitive Disorders. Journal of medicinal chemistry 67 (15) (2024)
Boqun Liu, Geoff Thompson, Manuela Jörg, Nicholas Barnes, David M Thal, Arthur Christopoulos, Ben Capuano, Celine Valant, Peter J Scammells
Discovery of 2-Methyl-5-(1 H -pyrazol-4-yl)pyridines and Related Heterocycles as Promising M 4 mAChR Positive Allosteric Modulators for the Treatment of Neurocognitive Disorders. Journal of medicinal chemistry (2024)
Jon Kyle Awalt, Anh T N Nguyen, Tim J Fyfe, Bui San Thai, Paul J White, Arthur Christopoulos, Manuela Jörg, Lauren T May, Peter J Scammells
Examining the Role of the Linker in Bitopic N 6 -Substituted Adenosine Derivatives Acting as Biased Adenosine A 1 Receptor Agonists. Journal of medicinal chemistry 65 (13) (2022)
Karen J Gregory, Manuela Jörg
Chemical biology-based approaches to study adenosine A 2A - dopamine D 2 receptor heteromers. Purinergic signalling (2022)
Owindeep Deo, Sadia Alvi, Vi Pham, Arthur Christopoulos, David M Thal, Manuela Jörg, Ben Capuano, Celine Valant, Peter J Scammells
The Design, Synthesis, and Evaluation of Novel 9-Arylxanthenedione-Based Allosteric Modulators for the δ - Opioid Receptor. Journal of medicinal chemistry 65 (18) (2022)
Manuela Jörg, Katrina S Madden
The right tools for the job: the central role for next generation chemical probes and chemistry-based target deconvolution methods in phenotypic drug discovery. RSC medicinal chemistry 12 (5) (2021)
Joshua W Conner, Daniel P Poole, Manuela Jörg, Nicholas A Veldhuis
New small molecule fluorescent probes for G protein-coupled receptors: valuable tools for drug discovery. Future medicinal chemistry 13 (1) (2020)
Samantha L Cooper, Mark Soave, Manuela Jörg, Peter J Scammells, Jeanette Woolard, Stephen J Hill
Probe dependence of allosteric enhancers on the binding affinity of adenosine A1 -receptor agonists at rat and human A1 -receptors measured using NanoBRET. British journal of pharmacology 176 (7) (2019)
Manuela Jörg, Emma T van der Westhuizen, Elham Khajehali, Wessel A C Burger, Jonathan M White, Kwok H C Choy, Andrew B Tobin, Patrick M Sexton, Celine Valant, Ben Capuano, Arthur Christopoulos, Peter J Scammells
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity. ACS chemical neuroscience 10 (3) (2018)
Manuela Jörg, Peter J Scammells
Guidelines for the Synthesis of Small-Molecule Irreversible Probes Targeting G Protein-Coupled Receptors. ChemMedChem 11 (14) (2016)