Stephen J Hill

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 49

Top Venues

British journal of pharmacology

Science signaling

International journal of molecular sciences

ACS medicinal chemistry letters

University of Nottingham

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Nottingham Aug 01 1995

United Kingdom

Professor of Molecular Pharmacology :: Life Sciences

University of Nottingham Aug 01 1989 - Jul 31 1995

United Kingdom

Reader in Molecular Pharmacology :: Physiology & Pharmacology

University of Nottingham Aug 01 1984 - Jul 31 1989

United Kingdom

Lecturer in Pharmacology :: Physiology & Pharmacology

University of Nottingham Oct 01 1981 - Aug 01 1984

United Kingdom

Lecturer in Pharmacology :: Pharmacy

University of Cambridge Sep 01 1979 - Sep 30 1981

United Kingdom

MRC Postdoctoral Research Fellow :: Pharmacolgy

Education History

University of Cambridge Sep 01 1976 - Sep 30 1979

United Kingdom

PHD :: Pharmacology

University of Bristol Sep 01 1973 - Jul 01 1976

United Kingdom

BSC :: Pharmacology

Publications

Carl W White, Simon Platt, Laura E Kilpatrick, Natasha Dale, Rekhati S Abhayawardana, Sebastian Dekkers, Nicholas D Kindon, Barrie Kellam, Michael J Stocks, Kevin D G Pfleger, Stephen J Hill
CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans. Science signaling 17 (828) (2024)
Rebecca Knight, Laura E Kilpatrick, Stephen J Hill, Michael J Stocks
Design, Synthesis, and Evaluation of a New Chemotype Fluorescent Ligand for the P2Y 2 Receptor. ACS medicinal chemistry letters 15 (7) (2024)
Sean A Cullum, Simon Platt, Natasha Dale, Oliver C Isaac, Edward S Wragg, Mark Soave, Dmitry B Veprintsev, Jeanette Woolard, Laura E Kilpatrick, Stephen J Hill
Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists. Communications biology 7 (1) (2024)
Foteini Patera, Sarah J Mistry, Nicholas D Kindon, Eleonora Comeo, Joëlle Goulding, Barrie Kellam, Laura E Kilpatrick, Hester Ann Franks, Stephen J Hill
A novel and selective fluorescent ligand for the study of adenosine A 2B receptors. Pharmacology research & perspectives 12 (4) (2024)
Sean A Cullum, Simon Platt, Natasha Dale, Oliver C Isaac, Edward S Wragg, Mark Soave, Dmitry B Veprintsev, Jeanette Woolard, Laura E Kilpatrick, Stephen J Hill
Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists. Communications biology 7 (1) (2024)
Rebecca Knight, Laura E Kilpatrick, Stephen J Hill, Michael J Stocks
Design, Synthesis, and Evaluation of a New Chemotype Fluorescent Ligand for the P2Y 2 Receptor. ACS medicinal chemistry letters 15 (7) (2024)
Foteini Patera, Sarah J Mistry, Nicholas D Kindon, Eleonora Comeo, Joëlle Goulding, Barrie Kellam, Laura E Kilpatrick, Hester Ann Franks, Stephen J Hill
A novel and selective fluorescent ligand for the study of adenosine A 2B receptors. Pharmacology research & perspectives 12 (4) (2024)
Carl W White, Simon Platt, Laura E Kilpatrick, Natasha Dale, Rekhati S Abhayawardana, Sebastian Dekkers, Nicholas D Kindon, Barrie Kellam, Michael J Stocks, Kevin D G Pfleger, Stephen J Hill
CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans. Science signaling 17 (828) (2024)
Carl W White, Simon Platt, Laura E Kilpatrick, Natasha Dale, Rekhati S Abhayawardana, Sebastian Dekkers, Nicholas D Kindon, Barrie Kellam, Michael J Stocks, Kevin D G Pfleger, Stephen J Hill
CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans. Science signaling 17 (828) (2024)
Carl W White, Simon Platt, Laura E Kilpatrick, Natasha Dale, Rekhati S Abhayawardana, Sebastian Dekkers, Nicholas D Kindon, Barrie Kellam, Michael J Stocks, Kevin D G Pfleger, Stephen J Hill
CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans. Science signaling 17 (828) (2024)
Sean A Cullum, Simon Platt, Natasha Dale, Oliver C Isaac, Edward S Wragg, Mark Soave, Dmitry B Veprintsev, Jeanette Woolard, Laura E Kilpatrick, Stephen J Hill
Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists. Communications biology 7 (1) (2024)
Carl W White, Simon Platt, Laura E Kilpatrick, Natasha Dale, Rekhati S Abhayawardana, Sebastian Dekkers, Nicholas D Kindon, Barrie Kellam, Michael J Stocks, Kevin D G Pfleger, Stephen J Hill
CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans. Science signaling 17 (828) (2024)
Patrizia Pannucci, Sophie R Jefferson, Jonathan Hampshire, Samantha L Cooper, Stephen J Hill, Jeanette Woolard
COVID-19-Induced Myocarditis: Pathophysiological Roles of ACE2 and Toll-like Receptors. International journal of molecular sciences 24 (6) (2023)
Patrizia Pannucci, Sophie R Jefferson, Jonathan Hampshire, Samantha L Cooper, Stephen J Hill, Jeanette Woolard
COVID-19-Induced Myocarditis: Pathophysiological Roles of ACE2 and Toll-like Receptors. International journal of molecular sciences 24 (6) (2023)
Patrizia Pannucci, Sophie R Jefferson, Jonathan Hampshire, Samantha L Cooper, Stephen J Hill, Jeanette Woolard
COVID-19-Induced Myocarditis: Pathophysiological Roles of ACE2 and Toll-like Receptors. International journal of molecular sciences 24 (6) (2023)
Charles S Lay, Albert Isidro-Llobet, Laura E Kilpatrick, Peter D Craggs, Stephen J Hill
Characterisation of IL-23 receptor antagonists and disease relevant mutants using fluorescent probes. Nature communications 14 (1) (2023)
Charles S Lay, Albert Isidro-Llobet, Laura E Kilpatrick, Peter D Craggs, Stephen J Hill
Characterisation of IL-23 receptor antagonists and disease relevant mutants using fluorescent probes. Nature communications 14 (1) (2023)
Sebastian Dekkers, Dehan Comez, Noemi Karsai, Marta Arimont-Segura, Meritxell Canals, Birgit Caspar, Chris de Graaf, Laura E Kilpatrick, Rob Leurs, Barrie Kellam, Stephen J Hill, Stephen J Briddon, Michael J Stocks
Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3). ACS medicinal chemistry letters 15 (1) (2023)
Stephen J Hill, Laura E Kilpatrick
Kinetic analysis of fluorescent ligand binding to cell surface receptors: Insights into conformational changes and allosterism in living cells. British journal of pharmacology (2023)
Sebastian Dekkers, Birgit Caspar, Joëlle Goulding, Nicholas D Kindon, Laura E Kilpatrick, Leigh A Stoddart, Stephen J Briddon, Barrie Kellam, Stephen J Hill, Michael J Stocks
Small-Molecule Fluorescent Ligands for the CXCR4 Chemokine Receptor. Journal of medicinal chemistry (2023)
Sebastian Dekkers, Dehan Comez, Noemi Karsai, Marta Arimont-Segura, Meritxell Canals, Birgit Caspar, Chris de Graaf, Laura E Kilpatrick, Rob Leurs, Barrie Kellam, Stephen J Hill, Stephen J Briddon, Michael J Stocks
Small Molecule Fluorescent Ligands for the Atypical Chemokine Receptor 3 (ACKR3). ACS medicinal chemistry letters 15 (1) (2023)
Charles S Lay, Albert Isidro-Llobet, Laura E Kilpatrick, Peter D Craggs, Stephen J Hill
Characterisation of IL-23 receptor antagonists and disease relevant mutants using fluorescent probes. Nature communications 14 (1) (2023)
Sean A Cullum, Dmitry B Veprintsev, Stephen J Hill
Kinetic analysis of endogenous β 2 -adrenoceptor-mediated cAMP GloSensor TM responses in HEK293 cells. British journal of pharmacology (2022)
Samantha L Cooper, Edward S Wragg, Patrizia Pannucci, Mark Soave, Stephen J Hill, Jeanette Woolard
Regionally selective cardiovascular responses to adenosine A 2A and A 2B receptor activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36 (4) (2022)
Charles S Lay, Laura E Kilpatrick, Peter D Craggs, Stephen J Hill
Use of NanoBiT and NanoBRET to characterise interleukin-23 receptor dimer formation in living cells. British journal of pharmacology (2022)
Edward S Wragg, Patrizia Pannucci, Stephen J Hill, Jeanette Woolard, Samantha L Cooper
Involvement of β-adrenoceptors in the cardiovascular responses induced by selective adenosine A 2A and A 2B receptor agonists. Pharmacology research & perspectives 10 (3) (2022)
Joëlle Goulding, Sarah J Mistry, Mark Soave, Jeanette Woolard, Stephen J Briddon, Carl W White, Barrie Kellam, Stephen J Hill
Subtype selective fluorescent ligands based on ICI 118,551 to study the human β2-adrenoceptor in CRISPR/Cas9 genome-edited HEK293T cells at low expression levels. Pharmacology research & perspectives 9 (3) (2022)
Charles S Lay, Laura E Kilpatrick, Peter D Craggs, Stephen J Hill
Use of NanoBiT and NanoBRET to characterise interleukin-23 receptor dimer formation in living cells. British journal of pharmacology (2022)
Sean A Cullum, Dmitry B Veprintsev, Stephen J Hill
Kinetic analysis of endogenous β 2 -adrenoceptor-mediated cAMP GloSensor™ responses in HEK293 cells. British journal of pharmacology (2022)
Charles S Lay, Laura E Kilpatrick, Peter D Craggs, Stephen J Hill
Use of NanoBiT and NanoBRET to characterise Interleukin-23 receptor dimer formation in living cells. British journal of pharmacology (2022)
Laura E Kilpatrick, Stephen J Hill
The use of fluorescence correlation spectroscopy to characterise the molecular mobility of G protein-coupled receptors in membrane microdomains: an update. Biochemical Society transactions 49 (4) (2022)
Peter Kolb, Terry Kenakin, Stephen P H Alexander, Marcel Bermudez, Laura M Bohn, Christian S Breinholt, Michel Bouvier, Stephen J Hill, Evi Kostenis, Kirill A Martemyanov, Rick R Neubig, H Ongun Onaran, Sudarshan Rajagopal, Bryan L Roth, Jana Selent, Arun K Shukla, Martha E Sommer, David E Gloriam
Community guidelines for GPCR ligand bias: IUPHAR review 32. British journal of pharmacology 179 (14) (2022)
Charles S Lay, Laura E Kilpatrick, Peter D Craggs, Stephen J Hill
Use of NanoBiT and NanoBRET to characterise interleukin-23 receptor dimer formation in living cells. British journal of pharmacology (2022)
Sean A Cullum, Dmitry B Veprintsev, Stephen J Hill
Kinetic analysis of endogenous β 2 -adrenoceptor-mediated cAMP GloSensor™ responses in HEK293 cells. British journal of pharmacology (2022)
Chloe J Peach, Laura E Kilpatrick, Jeanette Woolard, Stephen J Hill
Use of NanoBiT and NanoBRET to monitor fluorescent VEGF-A binding kinetics to VEGFR2/NRP1 heteromeric complexes in living cells. British journal of pharmacology 178 (12) (2021)
Samantha L Cooper, Eleanor Boyle, Sophie R Jefferson, Calum R A Heslop, Pirathini Mohan, Gearry G J Mohanraj, Hamza A Sidow, Rory C P Tan, Stephen J Hill, Jeanette Woolard
Role of the Renin-Angiotensin-Aldosterone and Kinin-Kallikrein Systems in the Cardiovascular Complications of COVID-19 and Long COVID. International journal of molecular sciences 22 (15) (2021)
Rachael L Grime, Joëlle Goulding, Romez Uddin, Leigh A Stoddart, Stephen J Hill, Amalie L Frischknecht, Stephen J Briddon, Mark Wheatley
Single molecule binding of a ligand to a G-protein-coupled receptor in real time using fluorescence correlation spectroscopy, rendered possible by nano-encapsulation in styrene maleic acid lipid particles. Nanoscale 12 (21) (2021)
Elizabeth K M Johnstone, Heng B See, Rekhati S Abhayawardana, Angela Song, K Johan Rosengren, Stephen J Hill, Kevin D G Pfleger
Investigation of Receptor Heteromers Using NanoBRET Ligand Binding. International journal of molecular sciences 22 (3) (2021)
Phuc N H Trinh, Daniel J W Chong, Katie Leach, Stephen J Hill, Joel D A Tyndall, Lauren T May, Andrea J Vernall, Karen J Gregory
Development of Covalent, Clickable Probes for Adenosine A1 and A3 Receptors. Journal of medicinal chemistry 64 (12) (2021)
Eleonora Comeo, Phuc Trinh, Anh T Nguyen, Cameron J Nowell, Nicholas D Kindon, Mark Soave, Leigh A Stoddart, Jonathan M White, Stephen J Hill, Barrie Kellam, Michelle L Halls, Lauren T May, Peter J Scammells
Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A1 Receptor in Living Cells. Journal of medicinal chemistry 64 (10) (2021)
Leigh A Stoddart, Laura E Kilpatrick, Ross Corriden, Barrie Kellam, Stephen J Briddon, Stephen J Hill
Efficient G protein coupling is not required for agonist-mediated internalization and membrane reorganization of the adenosine A3 receptor. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35 (4) (2021)
Samantha L Cooper, Julie March, Andrea R Sabbatini, Stephen J Hill, Manuela Jörg, Peter J Scammells, Jeanette Woolard
The effect of two selective A1 -receptor agonists and the bitopic ligand VCP746 on heart rate and regional vascular conductance in conscious rats. British journal of pharmacology 177 (2) (2020)
Mark Soave, Stephen J Briddon, Stephen J Hill, Leigh A Stoddart
Fluorescent ligands: Bringing light to emerging GPCR paradigms. British journal of pharmacology 177 (5) (2020)
Leigh A Stoddart, Nicholas D Kindon, Omolade Otun, Clare R Harwood, Foteini Patera, Dmitry B Veprintsev, Jeanette Woolard, Stephen J Briddon, Hester Ann Franks, Stephen J Hill, Barrie Kellam
Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells. Communications biology 3 (1) (2020)
Samantha L Cooper, Mark Soave, Manuela Jörg, Peter J Scammells, Jeanette Woolard, Stephen J Hill
Probe dependence of allosteric enhancers on the binding affinity of adenosine A1 -receptor agonists at rat and human A1 -receptors measured using NanoBRET. British journal of pharmacology 176 (7) (2019)
Monica Bouzo-Lorenzo, Leigh A Stoddart, Lizi Xia, Adriaan P IJzerman, Laura H Heitman, Stephen J Briddon, Stephen J Hill
A live cell NanoBRET binding assay allows the study of ligand-binding kinetics to the adenosine A3 receptor. Purinergic signalling 15 (2) (2019)
Chloe J Peach, Laura E Kilpatrick, Jeanette Woolard, Stephen J Hill
Comparison of the ligand-binding properties of fluorescent VEGF-A isoforms to VEGF receptor 2 in living cells and membrane preparations using NanoBRET. British journal of pharmacology 176 (17) (2019)
Mark Soave, Barrie Kellam, Jeanette Woolard, Stephen J Briddon, Stephen J Hill
NanoBiT Complementation to Monitor Agonist-Induced Adenosine A1 Receptor Internalization. SLAS discovery : advancing life sciences R & D 25 (2) (2019)
Leigh A Stoddart, Andrea J Vernall, Monica Bouzo-Lorenzo, Reggie Bosma, Albert J Kooistra, Chris de Graaf, Henry F Vischer, Rob Leurs, Stephen J Briddon, Barrie Kellam, Stephen J Hill
Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells. Scientific reports 8 (1) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Stephen J Hill