Peter J Scammells (Peter Scammells)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 40

Top Venues

Journal of medicinal chemistry

ChemMedChem

mBio

Molecular pharmaceutics

Monash Institute of Pharmaceutical Sciences

Griffith University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Monash Institute of Pharmaceutical Sciences

Australia

Professor of Medicinal Chemistry :: Medicinal Chemistry

Deakin University - Geelong Campus at Waurn Ponds

Australia

Lecturer - Senior Lecturer :: School of Chemical & Biological Sciences

Technische Universitat Darmstadt

Germany

Alexander von Humboldt Fellow :: Institute for Organic Chemistry

University of South Florida

United States

Research Associate :: College of Medicine

Education History

Griffith University

Australia

PHD :: School of Science

Publications

Rebecca C S Edgar, Tess R Malcolm, Ghizal Siddiqui, Carlo Giannangelo, Natalie A Counihan, Matthew Challis, Sandra Duffy, Mrittika Chowdhury, Jutta Marfurt, Madeline Dans, Grennady Wirjanata, Rintis Noviyanti, Kajal Daware, Chathura D Suraweera, Ric N Price, Sergio Wittlin, Vicky Marie Avery, Nyssa Drinkwater, Susan A Charman, Darren John Creek, Tania F de Koning-Ward, Peter J Scammells, Sheena McGowan
On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity. mBio 15 (6) (2024)
Eleonora Comeo, Joëlle Goulding, Chia-Yang Lin, Marleen Groenen, Jeanette Woolard, Nicholas D Kindon, Clare R Harwood, Simon Platt, Stephen J Briddon, Laura E Kilpatrick, Peter J Scammells, Stephen J Hill, Barrie Kellam
Ligand-Directed Labeling of the Adenosine A 1 Receptor in Living Cells. Journal of medicinal chemistry 67 (14) (2024)
Boqun Liu, Geoff Thompson, Manuela Jörg, Nicholas Barnes, David M Thal, Arthur Christopoulos, Ben Capuano, Celine Valant, Peter J Scammells
Discovery of 2-Methyl-5-(1 H -pyrazol-4-yl)pyridines and Related Heterocycles as Promising M 4 mAChR Positive Allosteric Modulators for the Treatment of Neurocognitive Disorders. Journal of medicinal chemistry 67 (15) (2024)
Rebecca C S Edgar, Tess R Malcolm, Ghizal Siddiqui, Carlo Giannangelo, Natalie A Counihan, Matthew Challis, Sandra Duffy, Mrittika Chowdhury, Jutta Marfurt, Madeline Dans, Grennady Wirjanata, Rintis Noviyanti, Kajal Daware, Chathura D Suraweera, Ric N Price, Sergio Wittlin, Vicky Marie Avery, Nyssa Drinkwater, Susan A Charman, Darren John Creek, Tania F de Koning-Ward, Peter J Scammells, Sheena McGowan
On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity. mBio 15 (6) (2024)
Boqun Liu, Geoff Thompson, Manuela Jörg, Nicholas Barnes, David M Thal, Arthur Christopoulos, Ben Capuano, Celine Valant, Peter J Scammells
Discovery of 2-Methyl-5-(1 H -pyrazol-4-yl)pyridines and Related Heterocycles as Promising M 4 mAChR Positive Allosteric Modulators for the Treatment of Neurocognitive Disorders. Journal of medicinal chemistry 67 (15) (2024)
Boqun Liu, Geoff Thompson, Manuela Jörg, Nicholas Barnes, David M Thal, Arthur Christopoulos, Ben Capuano, Celine Valant, Peter J Scammells
Discovery of 2-Methyl-5-(1 H -pyrazol-4-yl)pyridines and Related Heterocycles as Promising M 4 mAChR Positive Allosteric Modulators for the Treatment of Neurocognitive Disorders. Journal of medicinal chemistry (2024)
Rebecca C S Edgar, Tess R Malcolm, Ghizal Siddiqui, Carlo Giannangelo, Natalie A Counihan, Matthew Challis, Sandra Duffy, Mrittika Chowdhury, Jutta Marfurt, Madeline Dans, Grennady Wirjanata, Rintis Noviyanti, Kajal Daware, Chathura D Suraweera, Ric N Price, Sergio Wittlin, Vicky Marie Avery, Nyssa Drinkwater, Susan A Charman, Darren John Creek, Tania F de Koning-Ward, Peter J Scammells, Sheena McGowan
On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity. mBio 15 (6) (2024)
Eleonora Comeo, Joëlle Goulding, Chia-Yang Lin, Marleen Groenen, Jeanette Woolard, Nicholas D Kindon, Clare R Harwood, Simon Platt, Stephen J Briddon, Laura E Kilpatrick, Peter J Scammells, Stephen J Hill, Barrie Kellam
Ligand-Directed Labeling of the Adenosine A 1 Receptor in Living Cells. Journal of medicinal chemistry 67 (14) (2024)
Eleonora Comeo, Joëlle Goulding, Chia-Yang Lin, Marleen Groenen, Jeanette Woolard, Nicholas D Kindon, Clare R Harwood, Simon Platt, Stephen J Briddon, Laura E Kilpatrick, Peter J Scammells, Stephen J Hill, Barrie Kellam
Ligand-Directed Labeling of the Adenosine A 1 Receptor in Living Cells. Journal of medicinal chemistry 67 (14) (2024)
Rebecca C S Edgar, Tess R Malcolm, Ghizal Siddiqui, Carlo Giannangelo, Natalie A Counihan, Matthew Challis, Sandra Duffy, Mrittika Chowdhury, Jutta Marfurt, Madeline Dans, Grennady Wirjanata, Rintis Noviyanti, Kajal Daware, Chathura D Suraweera, Ric N Price, Sergio Wittlin, Vicky Marie Avery, Nyssa Drinkwater, Susan A Charman, Darren John Creek, Tania F de Koning-Ward, Peter J Scammells, Sheena McGowan
On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity. mBio (2024)
Eleonora Comeo, Joëlle Goulding, Chia-Yang Lin, Marleen Groenen, Jeanette Woolard, Nicholas D Kindon, Clare R Harwood, Simon Platt, Stephen J Briddon, Laura E Kilpatrick, Peter J Scammells, Stephen J Hill, Barrie Kellam
Ligand-Directed Labeling of the Adenosine A 1 Receptor in Living Cells. Journal of medicinal chemistry 67 (14) (2024)
Eleonora Comeo, Joëlle Goulding, Chia-Yang Lin, Marleen Groenen, Jeanette Woolard, Nicholas D Kindon, Clare R Harwood, Simon Platt, Stephen J Briddon, Laura E Kilpatrick, Peter J Scammells, Stephen J Hill, Barrie Kellam
Ligand-Directed Labeling of the Adenosine A 1 Receptor in Living Cells. Journal of medicinal chemistry (2024)
Jon Kyle Awalt, Anh T N Nguyen, Tim J Fyfe, Bui San Thai, Paul J White, Arthur Christopoulos, Manuela Jörg, Lauren T May, Peter J Scammells
Examining the Role of the Linker in Bitopic N 6 -Substituted Adenosine Derivatives Acting as Biased Adenosine A 1 Receptor Agonists. Journal of medicinal chemistry 65 (13) (2022)
Rebecca C S Edgar, Ghizal Siddiqui, Katheryn Hjerrild, Tess R Malcolm, Natalie B Vinh, Chaille T Webb, Clare Holmes, Christopher A MacRaild, Hope C Chernih, Willy W Suen, Natalie A Counihan, Darren John Creek, Peter J Scammells, Sheena McGowan, Tania F de Koning-Ward
Genetic and chemical validation of Plasmodium falciparum aminopeptidase Pf A-M17 as a drug target in the hemoglobin digestion pathway. eLife 11 (2022)
Owindeep Deo, Sadia Alvi, Vi Pham, Arthur Christopoulos, David M Thal, Manuela Jörg, Ben Capuano, Celine Valant, Peter J Scammells
The Design, Synthesis, and Evaluation of Novel 9-Arylxanthenedione-Based Allosteric Modulators for the δ - Opioid Receptor. Journal of medicinal chemistry 65 (18) (2022)
Matthew C L Wakeham, Briana J Davie, David K Chalmers, Arthur Christopoulos, Ben Capuano, Celine Valant, Peter J Scammells
Structural Features of Iperoxo-BQCA Muscarinic Acetylcholine Receptor Hybrid Ligands Determining Subtype Selectivity and Efficacy. ACS chemical neuroscience 13 (1) (2021)
Cassandra Yong, Shane M Devine, Anne-Catherine Abel, Stefan D Tomlins, Divya Muthiah, Xuexin Gao, Richard Callaghan, Michel O Steinmetz, Andrea E Prota, Ben Capuano, Peter J Scammells
1,3-Benzodioxole-Modified Noscapine Analogues: Synthesis, Antiproliferative Activity, and Tubulin-Bound Structure. ChemMedChem 16 (18) (2021)
Eleonora Comeo, Phuc Trinh, Anh T Nguyen, Cameron J Nowell, Nicholas D Kindon, Mark Soave, Leigh A Stoddart, Jonathan M White, Stephen J Hill, Barrie Kellam, Michelle L Halls, Lauren T May, Peter J Scammells
Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A1 Receptor in Living Cells. Journal of medicinal chemistry 64 (10) (2021)
Matthew R Bentley, Olga V Ilyichova, Geqing Wang, Martin L Williams, Gaurav Sharma, Wesam S Alwan, Rebecca L Whitehouse, Biswaranjan Mohanty, Peter J Scammells, Begoña Heras, Jennifer L Martin, Makrina Totsika, Ben Capuano, Bradley C Doak, Martin J Scanlon
Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX). Journal of medicinal chemistry 63 (13) (2020)
Manuela Jörg, Elham Khajehali, Emma T van der Westhuizen, K H C Choy, David M Shackleford, Andrew B Tobin, Patrick M Sexton, Celine Valant, Ben Capuano, Arthur Christopoulos, Peter J Scammells
Development of Novel 4-Arylpyridin-2-one and 6-Arylpyrimidin-4-one Positive Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor. ChemMedChem 16 (1) (2020)
Jisook Lee, Nyssa Drinkwater, Sheena McGowan, Peter J Scammells
A Structure-Activity Relationship Study of Novel Hydroxamic Acid Inhibitors around the S1 Subsite of Human Aminopeptidase N. ChemMedChem 16 (1) (2020)
Eleonora Comeo, Nicholas D Kindon, Mark Soave, Leigh A Stoddart, Laura E Kilpatrick, Peter J Scammells, Stephen J Hill, Barrie Kellam
Subtype-Selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A2A Receptor. Journal of medicinal chemistry 63 (5) (2020)
Mansura Akter, Nyssa Drinkwater, Shane M Devine, Simon C Drew, Bankala Krishnarjuna, Cael O Debono, Geqing Wang, Martin J Scanlon, Peter J Scammells, Sheena McGowan, Christopher A MacRaild, Raymond S Norton
Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe. ChemMedChem 14 (5) (2019)
Natalie B Vinh, Nyssa Drinkwater, Tess R Malcolm, Michael Kassiou, Leonardo Lucantoni, Peter M Grin, Georgina S Butler, Sandra Duffy, Christopher M Overall, Vicky M Avery, Peter J Scammells, Sheena McGowan
Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases. Journal of medicinal chemistry 62 (2) (2019)
Cassandra Yong, Shane M Devine, Xuexin Gao, Angelina Yan, Richard Callaghan, Ben Capuano, Peter J Scammells
A Novel Class of N-Sulfonyl and N-Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells. ChemMedChem 14 (23) (2019)
Jisook Lee, Natalie B Vinh, Nyssa Drinkwater, Wei Yang, Komagal Kannan Sivaraman, Luke S Schembri, Michelle Gazdik, Peter M Grin, Georgina S Butler, Christopher M Overall, Susan A Charman, Sheena McGowan, Peter J Scammells
Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions. Journal of medicinal chemistry 62 (15) (2019)
Carmen Klein Herenbrink, Ravi Verma, Herman D Lim, Anitha Kopinathan, Alastair Keen, Jeremy Shonberg, Christopher J Draper-Joyce, Peter J Scammells, Arthur Christopoulos, Jonathan A Javitch, Ben Capuano, Lei Shi, J Robert Lane
Molecular Determinants of the Intrinsic Efficacy of the Antipsychotic Aripiprazole. ACS chemical biology 14 (8) (2019)
Samantha L Cooper, Mark Soave, Manuela Jörg, Peter J Scammells, Jeanette Woolard, Stephen J Hill
Probe dependence of allosteric enhancers on the binding affinity of adenosine A1 -receptor agonists at rat and human A1 -receptors measured using NanoBRET. British journal of pharmacology 176 (7) (2019)
Tim J Fyfe, Barrie Kellam, David A Sykes, Ben Capuano, Peter J Scammells, J Robert Lane, Steven J Charlton, Shailesh N Mistry
Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D2 Receptor. Journal of medicinal chemistry 62 (21) (2019)
Manuela Jörg, Emma T van der Westhuizen, Elham Khajehali, Wessel A C Burger, Jonathan M White, Kwok H C Choy, Andrew B Tobin, Patrick M Sexton, Celine Valant, Ben Capuano, Arthur Christopoulos, Peter J Scammells
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity. ACS chemical neuroscience 10 (3) (2018)
Divya Muthiah, Georgia K Henshaw, Aaron J DeBono, Ben Capuano, Peter J Scammells, Richard Callaghan
Overcoming P-Glycoprotein-Mediated Drug Resistance with Noscapine Derivatives. Drug metabolism and disposition: the biological fate of chemicals 47 (2) (2018)
Juliana C C Dallagnol, Elham Khajehali, Emma T van der Westhuizen, Manuela Jörg, Celine Valant, Alan G Gonçalves, Ben Capuano, Arthur Christopoulos, Peter J Scammells
Synthesis and Pharmacological Evaluation of Heterocyclic Carboxamides: Positive Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor with Weak Agonist Activity and Diverse Modulatory Profiles. Journal of medicinal chemistry 61 (7) (2018)
Anitha Kopinathan, Christopher Draper-Joyce, Monika Szabo, Arthur Christopoulos, Peter J Scammells, J Robert Lane, Ben Capuano
Subtle Modifications to the Indole-2-carboxamide Motif of the Negative Allosteric Modulator N-(( trans)-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1 H)-yl)ethyl)cyclohexyl)-1 H-indole-2-carboxamide (SB269652) Yield Dramatic Changes in Pharmacological Activity at the Dopamine D2 Receptor. Journal of medicinal chemistry 62 (1) (2018)
Tim J Fyfe, Barbara Zarzycka, Herman D Lim, Barrie Kellam, Shailesh N Mistry, Vsevolod Katritch, Peter J Scammells, J Robert Lane, Ben Capuano
A Thieno[2,3- d]pyrimidine Scaffold Is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor. Journal of medicinal chemistry 62 (1) (2018)
Luigi Aurelio, Jo-Anne Baltos, Leigh Ford, Anh T N Nguyen, Manuela Jörg, Shane M Devine, Celine Valant, Paul J White, Arthur Christopoulos, Lauren T May, Peter J Scammells
A Structure-Activity Relationship Study of Bitopic N6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists. Journal of medicinal chemistry 61 (5) (2018)
Hywel D Williams, Leigh Ford, Sifei Han, Kristian J Tangso, Shea Lim, David M Shackleford, David T Vodak, Hassan Benameur, Colin W Pouton, Peter J Scammells, Christopher J H Porter
Enhancing the Oral Absorption of Kinase Inhibitors Using Lipophilic Salts and Lipid-Based Formulations. Molecular pharmaceutics 15 (12) (2018)
Raymond Lam, Arisbel B Gondin, Meritxell Canals, Barrie Kellam, Stephen J Briddon, Bim Graham, Peter J Scammells
Fluorescently Labeled Morphine Derivatives for Bioimaging Studies. Journal of medicinal chemistry 61 (3) (2018)
Shane M Devine, Cassandra Yong, Dzifa Amenuvegbe, Luigi Aurelio, Divya Muthiah, Colin W Pouton, Richard Callaghan, Ben Capuano, Peter J Scammells
Synthesis and Pharmacological Evaluation of Noscapine-Inspired 5-Substituted Tetrahydroisoquinolines as Cytotoxic Agents. Journal of medicinal chemistry 61 (18) (2018)
Yasemin Sahbaz, Tri-Hung Nguyen, Leigh Ford, Claire L McEvoy, Hywel D Williams, Peter J Scammells, Christopher J H Porter
Ionic Liquid Forms of Weakly Acidic Drugs in Oral Lipid Formulations: Preparation, Characterization, in Vitro Digestion, and in Vivo Absorption Studies. Molecular pharmaceutics 14 (11) (2017)
Manuela Jörg, Alisa Glukhova, Alaa Abdul-Ridha, Elizabeth A Vecchio, Anh T N Nguyen, Patrick M Sexton, Paul J White, Lauren T May, Arthur Christopoulos, Peter J Scammells
Novel Irreversible Agonists Acting at the A1 Adenosine Receptor. Journal of medicinal chemistry 59 (24) (2016)

Peter J Scammells.css-eqlu8i{font-size:small;padding-left:4px;} (Peter Scammells)

Publication Activity (10 Years)

Top Topics

Top Venues

Peter J Scammells (Peter Scammells)