Marcel Doerflinger

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 20

Top Venues

The EMBO journal

Cell death & disease

Proceedings of the National Academy of Sciences of the United States of America

The Biochemical journal

Walter and Eliza Hall Institute of Medical Research

La Trobe University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Walter and Eliza Hall Institute of Medical Research Apr 01 2016

Australia

Postdoctoral Fellow :: Infectious Diseases and Immune Defence

Education History

La Trobe University

Australia

PHD :: Biochemistry and Genetics

University of Stuttgart

Germany

MSC

University of Edinburgh Sep 01 2007 - Mar 30 2008

United Kingdom

BSC :: Division of Pathway Medicine

Publications

Stefanie M Bader, James P Cooney, Reet Bhandari, Liana Mackiewicz, Merle Dayton, Dylan Sheerin, Smitha Rose Georgy, James G Murphy, Kathryn C Davidson, Cody C Allison, Marc Pellegrini, Marcel Doerflinger
Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo. Cell death & disease 15 (1) (2024)
Stefanie M Bader, James P Cooney, Reet Bhandari, Liana Mackiewicz, Merle Dayton, Dylan Sheerin, Smitha Rose Georgy, James G Murphy, Kathryn C Davidson, Cody C Allison, Marc Pellegrini, Marcel Doerflinger
Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo. Cell death & disease 15 (1) (2024)
Stefanie M Bader, James P Cooney, Reet Bhandari, Liana Mackiewicz, Merle Dayton, Dylan Sheerin, Smitha Rose Georgy, James G Murphy, Kathryn C Davidson, Cody C Allison, Marc Pellegrini, Marcel Doerflinger
Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo. Cell death & disease 15 (1) (2024)
Stefanie M Bader, James P Cooney, Reet Bhandari, Liana Mackiewicz, Merle Dayton, Dylan Sheerin, Smitha Rose Georgy, James G Murphy, Kathryn C Davidson, Cody C Allison, Marc Pellegrini, Marcel Doerflinger
Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo. Cell death & disease 15 (1) (2024)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal 42 (5) (2023)
Simon P Preston, Cody C Allison, Jan Schaefer, William Clow, Stefanie M Bader, Sophie Collard, Wasan O Forsyth, Michelle P Clark, Alexandra L Garnham, Connie Li Wai Suen, Thanushi Peiris, Jack Teale, Liana Mackiewicz, Sophia Davidson, Marcel Doerflinger, Marc Pellegrini
A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection. Cell death & disease 14 (2) (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal 42 (5) (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal (2023)
Sarah E Garnish, Katherine R Martin, Maria Kauppi, Victoria E Jackson, Rebecca Ambrose, Vik Ven Eng, Shene Chiou, Yanxiang Meng, Daniel Frank, Emma C Tovey Crutchfield, Komal M Patel, Annette V Jacobsen, Georgia K Atkin-Smith, Ladina Di Rago, Marcel Doerflinger, Christopher R Horne, Cathrine Hall, Samuel N Young, Matthew C Cook, Vicki Athanasopoulos, Carola G Vinuesa, Kate E Lawlor, Ian P Wicks, Gregor Ebert, Ashley P Ng, Charlotte A Slade, Jaclyn S Pearson, André L Samson, John Silke, James G Murphy, Joanne M Hildebrand
A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation. Nature communications 14 (1) (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal 42 (5) (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal 42 (5) (2023)
Simon P Preston, Cody C Allison, Jan Schaefer, William Clow, Stefanie M Bader, Sophie Collard, Wasan O Forsyth, Michelle P Clark, Alexandra L Garnham, Connie Li Wai Suen, Thanushi Peiris, Jack Teale, Liana Mackiewicz, Sophia Davidson, Marcel Doerflinger, Marc Pellegrini
A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection. Cell death & disease 14 (2) (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal 42 (5) (2023)
Stefanie M Bader, James P Cooney, Dylan Sheerin, George Taiaroa, Leigh Harty, Kathryn C Davidson, Liana Mackiewicz, Merle Dayton, Stephen Wilcox, Lachlan W Whitehead, Kelly L Rogers, Smitha Rose Georgy, Anna K Coussens, Samantha L Grimley, Vincent D A Corbin, Miranda E Pitt, Lachlan J M Coin, Raelene Pickering, Merlin C Thomas, Cody C Allison, Julie L McAuley, Damian F J Purcell, Marcel Doerflinger, Marc Pellegrini
SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates. Proceedings of the National Academy of Sciences of the United States of America 120 (32) (2023)
Simon P Preston, Cody C Allison, Jan Schaefer, William Clow, Stefanie M Bader, Sophie Collard, Wasan O Forsyth, Michelle P Clark, Alexandra L Garnham, Connie Li Wai Suen, Thanushi Peiris, Jack Teale, Liana Mackiewicz, Sophia Davidson, Marcel Doerflinger, Marc Pellegrini
A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection. Cell death & disease 14 (2) (2023)
Stefanie M Bader, James P Cooney, Marc Pellegrini, Marcel Doerflinger
Programmed cell death: the pathways to severe COVID-19? The Biochemical journal 479 (5) (2022)
Sven Engel, Marcel Doerflinger, Ariane R Lee, Andreas Strasser, Marco J Herold, Sammy Bedoui, Annabell Bachem
Caspase-2 does not play a critical role in cell death induction and bacterial clearance during Salmonella infection. Cell death and differentiation 28 (12) (2021)
Phillip Pymm, Amy Adair, Li-Jin Chan, James P Cooney, Francesca L Mordant, Cody C Allison, Ester Lopez, Ebene R Haycroft, Matthew T O'Neill, Li Lynn Tan, Melanie H Dietrich, Damien Drew, Marcel Doerflinger, Michael A Dengler, Nichollas E Scott, Adam K Wheatley, Nicholas A Gherardin, Hariprasad Venugopal, Deborah Cromer, Miles P Davenport, Raelene Pickering, Dale I Godfrey, Damian F J Purcell, Stephen J Kent, Amy W Chung, Kanta Subbarao, Marc Pellegrini, Alisa Glukhova, Wai-Hong Tham
Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice. Proceedings of the National Academy of Sciences of the United States of America 118 (19) (2021)
Theresa Klemm, Gregor Ebert, Dale J Calleja, Cody C Allison, Lachlan W Richardson, Jonathan P Bernardini, Bernadine G C Lu, Nathan W Kuchel, Christoph Grohmann, Yuri Shibata, Zhong Yan Gan, James P Cooney, Marcel Doerflinger, Amanda E Au, Timothy R Blackmore, Gerbrand J van der Heden van Noort, Paul P Geurink, Huib Ovaa, Janet Newman, Alan Riboldi-Tunnicliffe, Peter E Czabotar, Jeffrey P Mitchell, Rebecca Feltham, Bernhard C Lechtenberg, Kym N Lowes, Grant Dewson, Marc Pellegrini, Guillaume L Lessene, David Komander
Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2. The EMBO journal 39 (18) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Marcel Doerflinger