Marcus Schewe

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 15

Top Topics

Molecular Dynamics Simulations

Positive Airway Pressure

Major Depressive Disorder

Top Venues

Nature communications

The Journal of general physiology

Proceedings of the National Academy of Sciences of the United States of America

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Berke Türkaydin, Marcus Schewe, Elena Barbara Riel, Friederike Schulz, Johann Biedermann, Thomas Baukrowitz, Han Sun
Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels. Nature communications 15 (1) (2024)
Berke Türkaydin, Marcus Schewe, Elena Barbara Riel, Friederike Schulz, Johann Biedermann, Thomas Baukrowitz, Han Sun
Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels. Nature communications 15 (1) (2024)
Berke Türkaydin, Marcus Schewe, Elena Barbara Riel, Friederike Schulz, Johann Biedermann, Thomas Baukrowitz, Han Sun
Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels. Nature communications 15 (1) (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Lea C Neelsen, Elena Barbara Riel, Susanne Rinné, Freya-Rebecca Schmid, Björn C Jürs, Mauricio Bedoya, Jan P Langer, Bisher Eymsh, Aytuğ K Kiper, Sönke Cordeiro, Niels Decher, Thomas Baukrowitz, Marcus Schewe
Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K 2P channel TALK-2. Nature communications 15 (1) (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Janina Sörmann, Marcus Schewe, Peter Proks, Thibault R H Jouen-Tachoire, Shanlin Rao, Elena Barbara Riel, Katherine E Agre, Amber Begtrup, John Dean, Maria Descartes, Jan Fischer, Alice Gardham, Carrie Lahner, Paul R Mark, Srikanth Muppidi, Pavel N Pichurin, Joseph Porrmann, Jens Schallner, Kirstin Smith, Volker Straub, Pradeep Vasudevan, Rebecca Willaert, Elisabeth P Carpenter, Karin E J Rödström, Michael G Hahn, Thomas Müller, Thomas Baukrowitz, Matthew E Hurles, Caroline Fiona Wright, Stephen J Tucker
Gain-of-function mutations in KCNK3 cause a developmental disorder with sleep apnea. Nature genetics 54 (10) (2022)
Peter Proks, Marcus Schewe, Linus J Conrad, Shanlin Rao, Kristin Rathje, Karin E J Rödström, Elisabeth P Carpenter, Thomas Baukrowitz, Stephen J Tucker
Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate. The Journal of general physiology 153 (8) (2021)
William Weijen Chang, Ann-Sophie Matt, Marcus Schewe, Marianne Musinszki, Sandra Grüssel, Jonas Brandenburg, David Garfield, Markus Bleich, Thomas Baukrowitz, Marian Y Hu
An otopetrin family proton channel promotes cellular acid efflux critical for biomineralization in a marine calcifier. Proceedings of the National Academy of Sciences of the United States of America 118 (30) (2021)
Elena Barbara Riel, Björn C Jürs, Sönke Cordeiro, Marianne Musinszki, Marcus Schewe, Thomas Baukrowitz
The versatile regulation of K2P channels by polyanionic lipids of the phosphoinositide and fatty acid metabolism. The Journal of general physiology 154 (2) (2021)
Marcus Schewe, Han Sun, Ümit Mert, Alexandra Mackenzie, Ashley C W Pike, Friederike Schulz, Cristina Constantin, Kirsty S Vowinkel, Linus J Conrad, Aytuğ K Kiper, Wendy González, Marianne Musinszki, Marie Tegtmeier, David C Pryde, Hassane Belabed, Marc Nazare, Bert L de Groot, Niels Decher, Bernd Fakler, Elisabeth P Carpenter, Stephen J Tucker, Thomas Baukrowitz
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels. Science (New York, N.Y.) 363 (6429) (2019)
Susanne Rinné, Aytuğ K Kiper, Kirsty S Vowinkel, David Ramírez, Marcus Schewe, Mauricio Bedoya, Diana Aser, Isabella Gensler, Michael F Netter, Phillip J Stansfeld, Thomas Baukrowitz, Wendy Gonzalez, Niels Decher
The molecular basis for an allosteric inhibition of K+-flux gating in K2P channels. eLife 8 (2019)
Niels Decher, Beatriz Ortiz-Bonnin, Corinna Friedrich, Marcus Schewe, Aytug K Kiper, Susanne Rinné, Gunnar Seemann, Rémi Peyronnet, Sven Zumhagen, Daniel Bustos, Jens Kockskämper, Peter Kohl, Steffen Just, Wendy González, Thomas Baukrowitz, Birgit Stallmeyer, Eric Schulze-Bahr
Sodium permeable and "hypersensitive" TREK-1 channels cause ventricular tachycardia. EMBO molecular medicine 9 (4) (2017)