Stephen J Tucker

Scopus Author ID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 27

Top Venues

Nature communications

The Journal of general physiology

PloS one

ACS nano

University of Oxford

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Oxford

United Kingdom

Professor of Biophysics :: Physics

Publications

Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
David Seiferth, Stephen J Tucker, Philip Charles Biggin
Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts. Physical chemistry chemical physics : PCCP (2023)
David Seiferth, Stephen J Tucker, Philip Charles Biggin
Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts. Physical chemistry chemical physics : PCCP (2023)
Linda X Phan, Aaron P Owji, Tingting Yang, Jason Crain, Mark S P Sansom, Stephen J Tucker
Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl - Channel. bioRxiv : the preprint server for biology (2023)
David Seiferth, Philip Charles Biggin, Stephen J Tucker
When is a hydrophobic gate not a hydrophobic gate? The Journal of general physiology 154 (11) (2022)
Mark Löbel, Sacha P Salphati, Kamel El Omari, Armin Wagner, Stephen J Tucker, Joanne L Parker, Simon Newstead
Structural basis for proton coupled cystine transport by cystinosin. Nature communications 13 (1) (2022)
Thibault R H Jouen-Tachoire, Stephen J Tucker, Paolo Tammaro
Ion channels as convergence points in the pathology of pulmonary arterial hypertension. Biochemical Society transactions 49 (4) (2022)
Janina Sörmann, Marcus Schewe, Peter Proks, Thibault R H Jouen-Tachoire, Shanlin Rao, Elena Barbara Riel, Katherine E Agre, Amber Begtrup, John Dean, Maria Descartes, Jan Fischer, Alice Gardham, Carrie Lahner, Paul R Mark, Srikanth Muppidi, Pavel N Pichurin, Joseph Porrmann, Jens Schallner, Kirstin Smith, Volker Straub, Pradeep Vasudevan, Rebecca Willaert, Elisabeth P Carpenter, Karin E J Rödström, Michael G Hahn, Thomas Müller, Thomas Baukrowitz, Matthew E Hurles, Caroline Fiona Wright, Stephen J Tucker
Gain-of-function mutations in KCNK3 cause a developmental disorder with sleep apnea. Nature genetics 54 (10) (2022)
Giulia Poli, Sonia Hasan, Silvia Belia, Marta Cenciarini, Stephen J Tucker, Paola Imbrici, Safa Shehab, Mauro Pessia, Stefano Brancorsini, Maria Cristina D'Adamo
Kcnj16 (Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa. International journal of molecular sciences 22 (11) (2021)
Shanlin Rao, Gianni Klesse, Charlotte I Lynch, Stephen J Tucker, Mark S P Sansom
Molecular Simulations of Hydrophobic Gating of Pentameric Ligand Gated Ion Channels: Insights into Water and Ions. The journal of physical chemistry. B 125 (4) (2021)
Peter Proks, Marcus Schewe, Linus J Conrad, Shanlin Rao, Kristin Rathje, Karin E J Rödström, Elisabeth P Carpenter, Thomas Baukrowitz, Stephen J Tucker
Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate. The Journal of general physiology 153 (8) (2021)
Linus J Conrad, Peter Proks, Stephen J Tucker
Effects of ionic strength on gating and permeation of TREK-2 K2P channels. PloS one 16 (10) (2021)
Charlotte I Lynch, Gianni Klesse, Shanlin Rao, Stephen J Tucker, Mark S P Sansom
Water Nanoconfined in a Hydrophobic Pore: Molecular Dynamics Simulations of Transmembrane Protein 175 and the Influence of Water Models. ACS nano (2021)
Karin E J Rödström, Aytuğ K Kiper, Wei Zhang, Susanne Rinné, Ashley C W Pike, Matthias Goldstein, Linus J Conrad, Martina Delbeck, Michael G Hahn, Heinrich Meier, Magdalena Platzk, Andrew Quigley, David Speedman, Leela Shrestha, Shubhashish M M Mukhopadhyay, Nicola A Burgess-Brown, Stephen J Tucker, Thomas Müller, Niels Decher, Elisabeth P Carpenter
A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature 582 (7812) (2020)
Gianni Klesse, Stephen J Tucker, Mark S P Sansom
Electric Field Induced Wetting of a Hydrophobic Gate in a Model Nanopore Based on the 5-HT3 Receptor Channel. ACS nano 14 (8) (2020)
Paola Imbrici, Ehsan Nematian-Ardestani, Sonia Hasan, Mauro Pessia, Stephen J Tucker, Maria Cristina D'Adamo
Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability. Pflugers Archiv : European journal of physiology 472 (7) (2020)
Johanna L Syrjanen, Kevin Michalski, Tsung-Han Chou, Timothy Grant, Shanlin Rao, Noriko Simorowski, Stephen J Tucker, Nikolaus Grigorieff, Hiro Furukawa
Structure and assembly of calcium homeostasis modulator proteins. Nature structural & molecular biology 27 (2) (2020)
Shanlin Rao, Gianni Klesse, Phillip J Stansfeld, Stephen J Tucker, Mark S P Sansom
A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates. Proceedings of the National Academy of Sciences of the United States of America 116 (28) (2019)
Marcus Schewe, Han Sun, Ümit Mert, Alexandra Mackenzie, Ashley C W Pike, Friederike Schulz, Cristina Constantin, Kirsty S Vowinkel, Linus J Conrad, Aytuğ K Kiper, Wendy González, Marianne Musinszki, Marie Tegtmeier, David C Pryde, Hassane Belabed, Marc Nazare, Bert L de Groot, Niels Decher, Bernd Fakler, Elisabeth P Carpenter, Stephen J Tucker, Thomas Baukrowitz
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels. Science (New York, N.Y.) 363 (6429) (2019)
Shanlin Rao, Gianni Klesse, Phillip J Stansfeld, Stephen J Tucker, Mark S P Sansom
A BEST example of channel structure annotation by molecular simulation. Channels (Austin, Tex.) 11 (4) (2017)
Ehsan Nematian-Ardestani, Viwan Jarerattanachat, Prafulla Aryal, Mark S P Sansom, Stephen J Tucker
The effects of stretch activation on ionic selectivity of the TREK-2 K2P K+ channel. Channels (Austin, Tex.) 11 (5) (2017)
Michael V Clausen, Viwan Jarerattanachat, Elisabeth P Carpenter, Mark S P Sansom, Stephen J Tucker
Asymmetric mechanosensitivity in a eukaryotic ion channel. Proceedings of the National Academy of Sciences of the United States of America 114 (40) (2017)
Emre Lacin, Prafulla Aryal, Ian W Glaaser, Karthik Bodhinathan, Eric Tsai, Nidaa Marsh, Stephen J Tucker, Mark S P Sansom, Paul A Slesinger
Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel. The Journal of general physiology 149 (8) (2017)
Alan P Reed, Giovanna Bucci, Firdaus Abd-Wahab, Stephen J Tucker
Correction: Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy. PloS one 11 (7) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Stephen J Tucker