Simon Newstead

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 29

Top Venues

Nature communications

eLife

Nature structural & molecular biology

Research square

University of Oxford

University of St Andrews (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Oxford Mar 01 2016

United Kingdom

Professor of Molecular Membrane Biology :: Biochemistry

University of Oxford Apr 01 2013 - Feb 29 2016

United Kingdom

Associate Professor :: Biochemistry

University of Oxford Dec 01 2009 - Dec 01 2014

United Kingdom

MRC Career Development Award Holder :: Biochemistry

Imperial College London Dec 01 2004 - Dec 01 2009

United Kingdom

Post-doctoral Research Associate :: Biomedical Sciences

Education History

University of St Andrews Sep 01 2001 - Dec 01 2004

United Kingdom

PHD :: Centre for Biomolecular Sciences

Publications

Simon Newstead, Joanne L Parker, Justin C Deme, Simon M Lichtinger, Gabriel Kuteyi, Philip Charles Biggin, Susan M Lea
Structural basis for antibiotic transport and inhibition in PepT2, the mammalian proton-coupled peptide transporter. Research square (2024)
Simon Newstead, Joanne L Parker, Justin C Deme, Simon M Lichtinger, Gabriel Kuteyi, Philip Charles Biggin, Susan M Lea
Structural basis for antibiotic transport and inhibition in PepT2, the mammalian proton-coupled peptide transporter. Research square (2024)
Simon Newstead
Future opportunities in solute carrier structural biology. Nature structural & molecular biology 31 (4) (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Simon Newstead
Future opportunities in solute carrier structural biology. Nature structural & molecular biology 31 (4) (2024)
Simon Newstead, Joanne L Parker, Justin C Deme, Simon M Lichtinger, Gabriel Kuteyi, Philip Charles Biggin, Susan M Lea
Structural basis for antibiotic transport and inhibition in PepT2, the mammalian proton-coupled peptide transporter. Research square (2024)
Simon M Lichtinger, Joanne L Parker, Simon Newstead, Philip Charles Biggin
The mechanism of mammalian proton-coupled peptide transporters. eLife 13 (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Simon M Lichtinger, Joanne L Parker, Simon Newstead, Philip Charles Biggin
The mechanism of mammalian proton-coupled peptide transporters. eLife 13 (2024)
Karin E J Rödström, Alexander Cloake, Janina Sörmann, Agnese Baronina, Kathryn H M Smith, Ashley C W Pike, Jackie Ang, Peter Proks, Marcus Schewe, Ingelise Holland-Kaye, Simon R Bushell, Jenna Elliott, Els Pardon, Thomas Baukrowitz, Raymond J Owens, Simon Newstead, Jan Steyaert, Elisabeth P Carpenter, Stephen J Tucker
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nature communications 15 (1) (2024)
Joanne L Parker, Takafumi Kato, Gabriel Kuteyi, Oleg Sitsel, Simon Newstead
Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1. Nature structural & molecular biology (2023)
Sille Remm, Dario De Vecchis, Jendrik Schöppe, Cedric A J Hutter, Imre Gonda, Michael Hohl, Simon Newstead, Lars V Schäfer, Markus A Seeger
Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410. Nature communications 14 (1) (2023)
Mark Löbel, Sacha P Salphati, Kamel El Omari, Armin Wagner, Stephen J Tucker, Joanne L Parker, Simon Newstead
Structural basis for proton coupled cystine transport by cystinosin. Nature communications 13 (1) (2022)
Maia Kinnebrew, Rachel E Woolley, Tillson Bertie Ansell, Eamon F X Byrne, Sara Frigui, Giovanni Luchetti, Ria Sircar, Sigrid Nachtergaele, Laurel Mydock-McGrane, Kathiresan Krishnan, Simon Newstead, Mark S P Sansom, Douglas F Covey, Christian Siebold, Rajat Rohatgi
Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain. Science advances 8 (22) (2022)
Joanne L Parker, Justin C Deme, Gabriel Kuteyi, Zhiyi Wu, Jiandong Huo, I David Goldman, Raymond J Owens, Philip Charles Biggin, Susan M Lea, Simon Newstead
Structural basis of antifolate recognition and transport by PCFT. Nature 595 (7865) (2021)
Andreas Gerondopoulos, Philipp Bräuer, Tomoaki Sobajima, Zhiyi Wu, Joanne L Parker, Philip Charles Biggin, Francis A Barr, Simon Newstead
A signal capture and proofreading mechanism for the KDEL-receptor explains selectivity and dynamic range in ER retrieval. eLife 10 (2021)
Joanne L Parker, Justin C Deme, Dimitrios Kolokouris, Gabriel Kuteyi, Philip Charles Biggin, Susan M Lea, Simon Newstead
Molecular basis for redox control by the human cystine/glutamate antiporter system xc. Nature communications 12 (1) (2021)
Joanne L Parker, Justin C Deme, Zhiyi Wu, Gabriel Kuteyi, Jiandong Huo, Raymond J Owens, Philip Charles Biggin, Susan M Lea, Simon Newstead
Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals. Science advances 7 (35) (2021)
Simon Newstead, Francis A Barr
Molecular basis for KDEL-mediated retrieval of escaped ER-resident proteins - SWEET talking the COPs. Journal of cell science 133 (19) (2020)
Simon Newstead
Insights into L-type heteromeric amino acid transporters. Nature structural & molecular biology 26 (6) (2020)
Iwan Zimmermann, Pascal Egloff, Cedric A J Hutter, Benedikt T Kuhn, Philipp Bräuer, Simon Newstead, Roger J P Dawson, Eric R Geertsma, Markus A Seeger
Generation of synthetic nanobodies against delicate proteins. Nature protocols 15 (5) (2020)
Joanne L Parker, Robin A Corey, Phillip J Stansfeld, Simon Newstead
Structural basis for substrate specificity and regulation of nucleotide sugar transporters in the lipid bilayer. Nature communications 10 (1) (2019)
Philipp Bräuer, Joanne L Parker, Andreas Gerondopoulos, Iwan Zimmermann, Markus A Seeger, Francis A Barr, Simon Newstead
Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor. Science (New York, N.Y.) 363 (6431) (2019)
Gurdeep S Minhas, Simon Newstead
Structural basis for prodrug recognition by the SLC15 family of proton-coupled peptide transporters. Proceedings of the National Academy of Sciences of the United States of America 116 (3) (2019)
Gurdeep S Minhas, Daniel Bawdon, Reyme Herman, Michelle Rudden, Andrew P Stone, A Gordon James, Gavin Hugh Thomas, Simon Newstead
Structural basis of malodour precursor transport in the human axilla. eLife 7 (2018)
Katharina Esther Julia Jungnickel, Joanne L Parker, Simon Newstead
Structural basis for amino acid transport by the CAT family of SLC7 transporters. Nature communications 9 (1) (2018)
Joanne L Parker, Chenghan Li, Allete Brinth, Zhi Wang, Lutz Vogeley, Nicolae Solcan, Gregory Ledderboge-Vucinic, Jessica M J Swanson, Martin Caffrey, Gregory A Voth, Simon Newstead
Proton movement and coupling in the POT family of peptide transporters. Proceedings of the National Academy of Sciences of the United States of America 114 (50) (2017)
Feng Zhang, Sonya M Hanson, Andres Jara-Oseguera, Dmitriy Krepkiy, Chanhyung Bae, Larry V Pearce, Peter M Blumberg, Simon Newstead, Kenton Jon Swartz
Engineering vanilloid-sensitivity into the rat TRPV2 channel. eLife 5 (2016)

Simon Newstead.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Simon Newstead