Marc Nazare (Marc Nazaré)

ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 38

Top Venues

Journal of medicinal chemistry

Angewandte Chemie (International ed. in English)

ChemMedChem

ACS chemical biology

Leibniz-Forschungsinstitut für Molekulare Pharmakologie

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Leibniz-Forschungsinstitut für Molekulare Pharmakologie

Germany

Group leader :: Medicinal Chemistry

Publications

Leonard Mach, Anahid Omran, Jara Bouma, Silke Radetzki, David A Sykes, Wolfgang Guba, Xiaoting Li, Calvin Höffelmeyer, Axel Hentsch, Thais Gazzi, Yelena Mostinski, Malgorzata Wasinska-Kalwa, Fabio de Molnier, Cas van der Horst, Jens Peter von Kries, Marc Vendrell, Tian Hua, Dmitry B Veprintsev, Laura H Heitman, Uwe Grether, Marc Nazare
Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB 1 R). Journal of medicinal chemistry (2024)
Thais Gazzi, Marina Lesina, Qinghua Wang, Alexandra Berninger, Silke Radetzki, Ihsan Ekin Demir, Larissa Kohlmann, Waldemar Meiser, Sebastian Wilke, Jens Peter von Kries, Hana Algül, Hai-Yu Hu, Marc Nazare
DOTA-Based Plectin-1 Targeted Contrast Agent Enables Detection of Pancreatic Cancer in Human Tissue. Angewandte Chemie (International ed. in English) 63 (26) (2024)
Leonard Mach, Anahid Omran, Jara Bouma, Silke Radetzki, David A Sykes, Wolfgang Guba, Xiaoting Li, Calvin Höffelmeyer, Axel Hentsch, Thais Gazzi, Yelena Mostinski, Malgorzata Wasinska-Kalwa, Fabio de Molnier, Cas van der Horst, Jens Peter von Kries, Marc Vendrell, Tian Hua, Dmitry B Veprintsev, Laura H Heitman, Uwe Grether, Marc Nazare
Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB 1 R). Journal of medicinal chemistry 67 (14) (2024)
Leonard Mach, Anahid Omran, Jara Bouma, Silke Radetzki, David A Sykes, Wolfgang Guba, Xiaoting Li, Calvin Höffelmeyer, Axel Hentsch, Thais Gazzi, Yelena Mostinski, Malgorzata Wasinska-Kalwa, Fabio de Molnier, Cas van der Horst, Jens Peter von Kries, Marc Vendrell, Tian Hua, Dmitry B Veprintsev, Laura H Heitman, Uwe Grether, Marc Nazare
Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB 1 R). Journal of medicinal chemistry 67 (14) (2024)
Leonard Mach, Anahid Omran, Jara Bouma, Silke Radetzki, David A Sykes, Wolfgang Guba, Xiaoting Li, Calvin Höffelmeyer, Axel Hentsch, Thais Gazzi, Yelena Mostinski, Malgorzata Wasinska-Kalwa, Fabio de Molnier, Cas van der Horst, Jens Peter von Kries, Marc Vendrell, Tian Hua, Dmitry B Veprintsev, Laura H Heitman, Uwe Grether, Marc Nazare
Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB 1 R). Journal of medicinal chemistry 67 (14) (2024)
Leonard Mach, Anahid Omran, Jara Bouma, Silke Radetzki, David A Sykes, Wolfgang Guba, Xiaoting Li, Calvin Höffelmeyer, Axel Hentsch, Thais Gazzi, Yelena Mostinski, Malgorzata Wasinska-Kalwa, Fabio de Molnier, Cas van der Horst, Jens Peter von Kries, Marc Vendrell, Tian Hua, Dmitry B Veprintsev, Laura H Heitman, Uwe Grether, Marc Nazare
Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB 1 R). Journal of medicinal chemistry 67 (14) (2024)
Thais Gazzi, Marina Lesina, Qinghua Wang, Alexandra Berninger, Silke Radetzki, Ihsan Ekin Demir, Larissa Kohlmann, Waldemar Meiser, Sebastian Wilke, Jens Peter von Kries, Hana Algül, Hai-Yu Hu, Marc Nazare
DOTA-Based Plectin-1 Targeted Contrast Agent Enables Detection of Pancreatic Cancer in Human Tissue. Angewandte Chemie (International ed. in English) (2024)
Thais Gazzi, Marina Lesina, Qinghua Wang, Alexandra Berninger, Silke Radetzki, Ihsan Ekin Demir, Larissa Kohlmann, Waldemar Meiser, Sebastian Wilke, Jens Peter von Kries, Hana Algül, Hai-Yu Hu, Marc Nazare
DOTA-Based Plectin-1 Targeted Contrast Agent Enables Detection of Pancreatic Cancer in Human Tissue. Angewandte Chemie (International ed. in English) 63 (26) (2024)
Edgar Specker, Radoslaw Wesolowski, Anja Schütz, Susann Matthes, Keven Mallow, Malgorzata Wasinska-Kalwa, Lars Winkler, Andreas Oder, Natalia V Alenina, Dirk Pleimes, Jens Peter von Kries, Udo Heinemann, Michael Bader, Marc Nazare
Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles as Highly Potent and In Vivo Efficacious Tryptophan Hydroxylase Inhibitors. Journal of medicinal chemistry (2023)
Murat Kücükdisli, Hassen Bel-Abed, Davide Cirillo, Wen-Ting Lo, Nina-Louisa Efrém, André Horatscheck, Liudmila Perepelittchenko, Polina Prokofeva, Theresa A L Ehret, Silke Radetzki, Martin Neuenschwander, Edgar Specker, Guillaume Médard, Susanne Müller, Stephanie Wilhelm, Bernhard Kuster, Jens Peter von Kries, Volker Haucke, Marc Nazare
Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition. Journal of medicinal chemistry (2023)
Paula Samsó, Philipp Alexander Koch, York Posor, Wen-Ting Lo, Hassane Belabed, Marc Nazare, Jocelyn Laporte, Volker Haucke
Antagonistic control of active surface integrins by myotubularin and phosphatidylinositol 3-kinase C2β in a myotubular myopathy model. Proceedings of the National Academy of Sciences of the United States of America 119 (40) (2022)
Edgar Specker, Susann Matthes, Radoslaw Wesolowski, Anja Schütz, Maik Grohmann, Natalia V Alenina, Dirk Pleimes, Keven Mallow, Martin Neuenschwander, Angelina Gogolin, Marie Weise, Jochen Pfeifer, Nandor Ziebart, Udo Heinemann, Jens Peter von Kries, Marc Nazare, Michael Bader
Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors. Journal of medicinal chemistry 65 (16) (2022)
Mónica Guberman, Miroslav Kosar, Anahid Omran, Erick M Carreira, Marc Nazare, Uwe Grether
Reverse Design toward Optimized Labeled Chemical Probes - Examples from the Endocannabinoid System. Chimia 76 (5) (2022)
Wen-Ting Lo, Hassane Belabed, Murat Kücükdisli, Juliane Metag, Yvette Roske, Polina Prokofeva, Yohei Ohashi, André Horatscheck, Davide Cirillo, Michael Krauss, Christopher Schmied, Martin Neuenschwander, Jens Peter von Kries, Guillaume Médard, Bernhard Kuster, Olga Perisic, Roger L Williams, Oliver Daumke, Bernard Payrastre, Sonia Severin, Marc Nazare, Volker Haucke
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α. Nature chemical biology (2022)
Xiao-Lu Li, Tong Ru, Armando Navarro-Vázquez, Peter Lindemann, Marc Nazare, Xu-Wen Li, Yue-Wei Guo, Han Sun
Weizhouochrones: Gorgonian-Derived Symmetric Dimers and Their Structure Elucidation Using Anisotropic NMR Combined with DP4+ Probability and CASE-3D. Journal of natural products 85 (7) (2022)
Hengxi Zhang, Carlos Modenutti, Yelha Phani Kumar Nekkanti, Maxime Denis, Iris A Bermejo, Jonathan Lefèbre, Kateryna Che, Dongyoon Kim, Marten Kagelmacher, Dennis Kurzbach, Marc Nazare, Christoph Rademacher
Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin. ACS chemical biology 17 (10) (2022)
María Isabel Fernández-Bachiller, Songhwan Hwang, María Elena Schembri, Peter Lindemann, Mónica Guberman, Svenja Herziger, Edgar Specker, Hans Matter, David W Will, Jörg Czech, Michael Wagner, Armin Bauer, Herman Schreuder, Kurt Ritter, Matthias Urmann, Volkmar Wehner, Han Sun, Marc Nazare
Probing Factor Xa Protein-Ligand Interactions: Accurate Free Energy Calculations and Experimental Validations of Two Series of High-Affinity Ligands. Journal of medicinal chemistry 65 (19) (2022)
F Teresa I Melder, Peter Lindemann, Alexander Welle, Vanessa Trouillet, Stefan Heißler, Marc Nazare, Matthias Selbach
Compound Interaction Screen on a Photoactivatable Cellulose Membrane (CISCM) Identifies Drug Targets. ChemMedChem 17 (19) (2022)
Thais Gazzi, Benjamin Brennecke, Kenneth Atz, Claudia Korn, David Sykes, Gabriel Forn-Cuni, Patrick Pfaff, Roman C Sarott, Matthias V Westphal, Yelena Mostinski, Leonard Mach, Malgorzata Wasinska-Kalwa, Marie Weise, Bradley L Hoare, Tamara Miljuš, Maira Mexi, Nicolas Roth, Eline J Koers, Wolfgang Guba, André Alker, Arne C Rufer, Eric A Kusznir, Sylwia Huber, Catarina Raposo, Elisabeth A Zirwes, Anja Osterwald, Anto Pavlovic, Svenja Moes, Jennifer Beck, Matthias Nettekoven, Irene Benito-Cuesta, Teresa Grande, Faye Drawnel, Gabriella Widmer, Daniela Holzer, Tom van der Wel, Harpreet K Mandhair, Michael Honer, Jürgen Fingerle, Jörg Scheffel, Johannes Broichhagen, Klaus Gawrisch, Julián Romero, Cecilia J Hillard, Zoltan V Varga, Mario van der Stelt, Pal Pacher, Jürg Gertsch, Christoph Ullmer, Peter J McCormick, Sergio Oddi, Herman P Spaink, Mauro Maccarrone, Dmitry B Veprintsev, Erick M Carreira, Uwe Grether, Marc Nazare
Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe. Chemical science 13 (19) (2022)
David M Carter, Edgar Specker, Piotr H Małecki, Jessica Przygodda, Krystyna Dudaniec, Manfred S Weiss, Udo Heinemann, Marc Nazare, Ulrich Gohlke
Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer. Journal of medicinal chemistry 64 (19) (2021)
Nis Halland, Friedemann Schmidt, Tilo Weiss, Ziyu Li, Jörg Czech, Joachim Saas, Danping Ding-Pfennigdorff, Matthias K Dreyer, Carsten Strübing, Marc Nazare
Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. Journal of medicinal chemistry 65 (2) (2021)
Ruben G G Leenders, Shoshy Alam Brinch, Sven T Sowa, Enya Amundsen-Isaksen, Albert Galera-Prat, Sudarshan Murthy, Sjoerd Aertssen, Johannes N Smits, Piotr Nieczypor, Eddy Damen, Anita Wegert, Marc Nazare, Lari Lehtiö, Shoshy A Brinch, Stefan Krauss
Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II. Journal of medicinal chemistry (2021)
Benjamin Brennecke, Qinghua Wang, Wolfgang Haap, Uwe Grether, Hai-Yu Hu, Marc Nazare
DOTAM-Based, Targeted, Activatable Fluorescent Probes for the Highly Sensitive and Selective Detection of Cancer Cells. Bioconjugate chemistry 32 (4) (2021)
Benjamin Brennecke, Thais Gazzi, Kenneth Atz, Jürgen Fingerle, Pascal Kuner, Torsten Schindler, Guy de Weck, Marc Nazare, Uwe Grether
Cannabinoid receptor type 2 ligands: an analysis of granted patents since 2010. Pharmaceutical patent analyst 10 (3) (2021)
Shengnan Xu, Qingyang Zhang, Xiaowan Han, Yali Wang, Xiang Wang, Marc Nazare, Jian-Dong Jiang, Hai-Yu Hu
Dual-Mode Detection of Bacterial 16S Ribosomal RNA in Tissues. ACS sensors 5 (6) (2020)
Yelena Mostinski, Guus J J E Heynen, Maria Pascual López-Alberca, Jerome Paul, Sandra Miksche, Silke Radetzki, David Schaller, Elena Shanina, Carola Seyffarth, Yuliya Kolomeets, Nandor Ziebart, Judith de Schryver, Sylvia Oestreich, Martin Neuenschwander, Yvette Roske, Udo Heinemann, Christoph Rademacher, Andrea Volkamer, Jens Peter von Kries, Walter Birchmeier, Marc Nazare
From Pyrazolones to Azaindoles: Evolution of Active-Site SHP2 Inhibitors Based on Scaffold Hopping and Bioisosteric Replacement. Journal of medicinal chemistry 63 (23) (2020)
Rana Alsalim, Peter Lindemann, María Pascual López-Alberca, Sandra Miksche, Werngard Czechtizky, Nis Halland, Marc Nazare
A Palladium-Catalyzed Domino Reaction To Access 3-Amino-2H-indazoles from Hydrazines and 2-Halobenzonitriles. Organic letters 22 (18) (2020)
Henry E Webel, Talia B Kimber, Silke Radetzki, Martin Neuenschwander, Marc Nazare, Andrea Volkamer
Revealing cytotoxic substructures in molecules using deep learning. Journal of computer-aided molecular design 34 (7) (2020)
Roman C Sarott, Matthias V Westphal, Patrick Pfaff, Claudia Korn, David A Sykes, Thais Gazzi, Benjamin Brennecke, Kenneth Atz, Marie Weise, Yelena Mostinski, Pattarin Hompluem, Eline Koers, Tamara Miljuš, Nicolas J Roth, Hermon Asmelash, Man C Vong, Jacopo Piovesan, Wolfgang Guba, Arne C Rufer, Eric A Kusznir, Sylwia Huber, Catarina Raposo, Elisabeth A Zirwes, Anja Osterwald, Anto Pavlovic, Svenja Moes, Jennifer Beck, Irene Benito-Cuesta, Teresa Grande, Samuel Ruiz de Martı N Esteban, Alexei Yeliseev, Faye Drawnel, Gabriella Widmer, Daniela Holzer, Tom van der Wel, Harpreet Mandhair, Cheng-Yin Yuan, William R Drobyski, Yurii Saroz, Natasha L Grimsey, Michael Honer, Jürgen Fingerle, Klaus Gawrisch, Julian Romero, Cecilia J Hillard, Zoltan V Varga, Mario van der Stelt, Pal Pacher, Jürg Gertsch, Peter J McCormick, Christoph Ullmer, Sergio Oddi, Mauro Maccarrone, Dmitry B Veprintsev, Marc Nazare, Uwe Grether, Erick M Carreira
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells. Journal of the American Chemical Society 142 (40) (2020)
Matthias Barone, Matthias Müller, Slim Chiha, Jiang Ren, Dominik Albat, Arne Soicke, Stephan Dohmen, Marco Klein, Judith Bruns, Maarten van Dinther, Robert Opitz, Peter Lindemann, Monika Beerbaum, Kathrin Motzny, Yvette Roske, Peter Schmieder, Rudolf Volkmer, Marc Nazare, Udo Heinemann, Hartmut Oschkinat, Peter Ten Dijke, Hans-Günther Schmalz, Ronald Kühne
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America 117 (47) (2020)
Benjamin Brennecke, Qinghua Wang, Qingyang Zhang, Hai-Yu Hu, Marc Nazare
An Activatable Lanthanide Luminescent Probe for Time-Gated Detection of Nitroreductase in Live Bacteria. Angewandte Chemie (International ed. in English) 59 (22) (2020)
Marcus Schewe, Han Sun, Ümit Mert, Alexandra Mackenzie, Ashley C W Pike, Friederike Schulz, Cristina Constantin, Kirsty S Vowinkel, Linus J Conrad, Aytuğ K Kiper, Wendy González, Marianne Musinszki, Marie Tegtmeier, David C Pryde, Hassane Belabed, Marc Nazare, Bert L de Groot, Niels Decher, Bernd Fakler, Elisabeth P Carpenter, Stephen J Tucker, Thomas Baukrowitz
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels. Science (New York, N.Y.) 363 (6429) (2019)
Qingyang Zhang, Shengnan Xu, Fangfang Lai, Yali Wang, Na Zhang, Marc Nazare, Hai-Yu Hu
Rapid Synthesis of γ-Halide/Pseudohalide-Substituted Cyanine Sensors with Programmed Generation of Singlet Oxygen. Organic letters 21 (7) (2019)
Jens Schoene, Thais Gazzi, Peter Lindemann, Mathias Christmann, Andrea Volkamer, Marc Nazare
Probing 2H-Indazoles as Templates for SGK1, Tie2, and SRC Kinase Inhibitors. ChemMedChem 14 (16) (2019)
Jessica Schulze, Hannes Baukmann, Robert Wawrzinek, Felix F Fuchsberger, Edgar Specker, Jonas Aretz, Marc Nazare, Christoph Rademacher
CellFy: A Cell-Based Fragment Screen against C-Type Lectins. ACS chemical biology 13 (12) (2018)
Jens Schoene, Hassen Bel Abed, Peter Schmieder, Mathias Christmann, Marc Nazare
A General One-Pot Synthesis of 2H-Indazoles Using an Organophosphorus-Silane System. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (36) (2018)
Jonas Aretz, Upendra R Anumala, Felix F Fuchsberger, Narges Molavi, Nandor Ziebart, Hengxi Zhang, Marc Nazare, Christoph Rademacher
Allosteric Inhibition of a Mammalian Lectin. Journal of the American Chemical Society 140 (44) (2018)
Upendra Rao Anumala, Jo Waaler, Yves Nkizinkiko, Alexander Ignatev, Katina Lazarow, Peter Lindemann, Petter Angell Olsen, Sudarshan Murthy, Ezeogo Obaji, Alexander G Majouga, Sergey Leonov, Jens Peter von Kries, Lari Lehtiö, Stefan Krauss, Marc Nazare
Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach. Journal of medicinal chemistry 60 (24) (2017)

Marc Nazare.css-eqlu8i{font-size:small;padding-left:4px;} (Marc Nazaré)

Publication Activity (10 Years)

Top Topics

Top Venues

Marc Nazare (Marc Nazaré)