Markus Müschen

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 28

Top Topics

Gene Expression

Acute Lymphoblastic Leukemia

Top Venues

Nature communications

Blood cancer discovery

Science advances

Communications biology

This page only lists publications with an associated author ORCID identifier.

Publications

Anthony K C Chan, Li Han, Christopher D Delaney, Xueer Wang, Elizaveta Mukhaleva, Mingli Li, Lu Yang, Sheela Pangeni Pokharel, Nicole M Mattson, Michelle Garcia, Bintao Wang, Xiaobao Xu, Leisi Zhang, Priyanka Singh, Zeinab Elsayed, Renee Chen, Benjamin Z Kuang, Jinhui Wang, Yate-Ching Yuan, Bryan Chen, Lai N Chan, Steven T Rosen, David A Horne, Markus Müschen, Jianjun Chen, Nagarajan Vaidehi, Scott A Armstrong, Rui Su, Chun-Wei David Chen
Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery. Science advances 10 (8) (2024)
Anthony K C Chan, Li Han, Christopher D Delaney, Xueer Wang, Elizaveta Mukhaleva, Mingli Li, Lu Yang, Sheela Pangeni Pokharel, Nicole M Mattson, Michelle Garcia, Bintao Wang, Xiaobao Xu, Leisi Zhang, Priyanka Singh, Zeinab Elsayed, Renee Chen, Benjamin Z Kuang, Jinhui Wang, Yate-Ching Yuan, Bryan Chen, Lai N Chan, Steven T Rosen, David A Horne, Markus Müschen, Jianjun Chen, Nagarajan Vaidehi, Scott A Armstrong, Rui Su, Chun-Wei David Chen
Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery. Science advances 10 (8) (2024)
Etienne Leveille, Shalin Kothari, Kadriye N Cosgun, Coraline Mlynarczyk, Markus Müschen
Tuning Responses to Polatuzumab Vedotin in B-cell Lymphoma. Cancer discovery 14 (9) (2024)
Anthony K C Chan, Li Han, Christopher D Delaney, Xueer Wang, Elizaveta Mukhaleva, Mingli Li, Lu Yang, Sheela Pangeni Pokharel, Nicole M Mattson, Michelle Garcia, Bintao Wang, Xiaobao Xu, Leisi Zhang, Priyanka Singh, Zeinab Elsayed, Renee Chen, Benjamin Z Kuang, Jinhui Wang, Yate-Ching Yuan, Bryan Chen, Lai N Chan, Steven T Rosen, David A Horne, Markus Müschen, Jianjun Chen, Nagarajan Vaidehi, Scott A Armstrong, Rui Su, Chun-Wei David Chen
Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery. Science advances 10 (8) (2024)
Adeleh Taghi Khani, Anil Kumar, Ashly Sanchez Ortiz, Kelly C Radecki, Soraya Aramburo, Sung June Lee, Zunsong Hu, Behzad Damirchi, Mary Y Lorenson, Xiwei Wu, Zhaohui Gu, William Stohl, Ignacio Sanz, Eric Meffre, Markus Müschen, Stephen J Forman, Jean L Koff, Ameae M Walker, Srividya Swaminathan
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms. Communications biology 6 (1) (2023)
Etienne Leveille, Shalin Kothari, Markus Müschen
Genetic Modeling of B-cell State Transitions for Rational Design of Lymphoma Therapies. Blood cancer discovery 4 (1) (2023)
Tim Wartewig, Jay C Daniels, Miriam Schulz, Erik Hameister, Abhinav Joshi, Joonhee Park, Emma Morrish, Anuroop Venkateswaran Venkatasubramani, Filippo M Cernilogar, Frits H A van Heijster, Christian Hundshammer, Heike Schneider, Filippos Konstantinidis, Judith V Gabler, Christine Klement, Henry Kurniawan, Calvin Law, Yujin Lee, Sara Choi, Joan Guitart, Ignasi Forne, Jérôme Giustinani, Markus Müschen, Salvia Jain, David M Weinstock, Roland Rad, Nicolas Ortonne, Franz Schilling, Gunnar Schotta, Axel Imhof, Dirk Brenner, Jaehyuk Choi, Juergen Ruland
PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma. Nature cancer (2023)
Adeleh Taghi Khani, Anil Kumar, Ashly Sanchez Ortiz, Kelly C Radecki, Soraya Aramburo, Sung June Lee, Zunsong Hu, Behzad Damirchi, Mary Y Lorenson, Xiwei Wu, Zhaohui Gu, William Stohl, Ignacio Sanz, Eric Meffre, Markus Müschen, Stephen J Forman, Jean L Koff, Ameae M Walker, Srividya Swaminathan
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms. Communications biology 6 (1) (2023)
Etienne Leveille, Shalin Kothari, Markus Müschen
Genetic Modeling of B-cell State Transitions for Rational Design of Lymphoma Therapies. Blood cancer discovery 4 (1) (2023)
Adeleh Taghi Khani, Anil Kumar, Ashly Sanchez Ortiz, Kelly C Radecki, Soraya Aramburo, Sung June Lee, Zunsong Hu, Behzad Damirchi, Mary Y Lorenson, Xiwei Wu, Zhaohui Gu, William Stohl, Ignacio Sanz, Eric Meffre, Markus Müschen, Stephen J Forman, Jean L Koff, Ameae M Walker, Srividya Swaminathan
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms. Communications biology 6 (1) (2023)
Etienne Leveille, Shalin Kothari, Markus Müschen
Genetic Modeling of B-cell State Transitions for Rational Design of Lymphoma Therapies. Blood cancer discovery 4 (1) (2023)
Etienne Leveille, Shalin Kothari, Markus Müschen
Genetic Modeling of B-cell State Transitions for Rational Design of Lymphoma Therapies. Blood cancer discovery 4 (1) (2023)
Jaewoong Lee, Mark E Robinson, Ruifeng Sun, Kohei Kume, Ning Ma, Kadriye Nehir Cosgun, Lai N Chan, Etienne Leveille, Huimin Geng, Vivasvan S Vykunta, Brian R Shy, Alexander Marson, Samuel Katz, Jianjun Chen, Elisabeth Paietta, Eric Meffre, Nagarajan Vaidehi, Markus Müschen
Dynamic phosphatase-recruitment controls B-cell selection and oncogenic signaling. bioRxiv : the preprint server for biology (2023)
Lai N Chan, Eamon Aghania, Etienne Leveille, Markus Müschen
Metabolic determinants of B-cell selection. Biochemical Society transactions 49 (3) (2022)
Ifat Geron, Angela Maria Savino, Hila Fishman, Noa Tal, John Brown, Virginia A Turati, Chela James, Jolanda Sarno, Michal Hameiri-Grossman, Yu Nee Lee, Avigail Rein, Hillary Maniriho, Yehudit Birger, Anna Zemlyansky, Inna Muler, Kara L Davis, Victoria Marcu-Malina, Nicole Mattson, Oren Parnas, Rabea Wagener, Ute Fischer, Joao T Barata, Catriona H M Jamieson, Markus Müschen, Chun-Wei David Chen, Arndt Borkhardt, Ilan Richard Kirsch, Arnon Nagler, Tariq Enver, Shai Izraeli
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia. Nature communications 13 (1) (2022)
Etienne Leveille, Shalin Kothari, Markus Müschen
Genetic Modeling of B-cell State Transitions for Rational Design of Lymphoma Therapies. Blood cancer discovery (2022)
Franz Ketzer, Hend Abdelrasoul, Mona Vogel, Ralf Marienfeld, Markus Müschen, Hassan Jumaa, Thomas Wirth, Alexey Ushmorov
CCND3 is indispensable for the maintenance of B-cell acute lymphoblastic leukemia. Oncogenesis 11 (1) (2022)
Veronika Ecker, Martina Stumpf, Lisa Brandmeier, Tanja Neumayer, Lisa Pfeuffer, Thomas Engleitner, Ingo Ringshausen, Nina Nelson, Manfred Jücker, Stefan Wanninger, Thorsten Zenz, Clemens Wendtner, Katrin Manske, Katja Steiger, Roland Rad, Markus Müschen, Juergen Ruland, Maike Buchner
Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia. Nature communications 12 (1) (2021)
Tsz-Yin Chan, Christina M Egbert, Julia E Maxson, Adam Siddiqui, Logan J Larsen, Kristina Kohler, Eranga Roshan Balasooriya, Katie L Pennington, Tsz-Ming Tsang, Madison Frey, Erik J Soderblom, Huimin Geng, Markus Müschen, Tetyana V Forostyan, Savannah Free, Gaelle Mercenne, Courtney J Banks, Jonard Corpuz Valdoz, Clifford J Whatcott, Jason M Foulks, David J Bearss, Thomas O'Hare, David Ching Siang Huang, Kenneth A Christensen, James D Moody, Steven L Warner, Jeffrey W Tyner, Joshua L Andersen
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Nature communications 12 (1) (2021)
Liang Xu, Ye Chen, Yulun Huang, Edwin Sandanaraj, John S Yu, Ruby Yu-Tong Lin, Pushkar Dakle, Xin-Yu Ke, Yuk Kien Chong, Lynnette Koh, Anand Mayakonda, Kassoum Nacro, Jeffrey Hill, Mo-Li Huang, Sigal Gery, See Wee Lim, Zhengyun Huang, Ying Xu, Jianxiang Chen, Longchuan Bai, Shaomeng Wang, Hiroaki Wakimoto, Tseng Tsai Yeo, Beng Ti Ang, Markus Müschen, Carol Tang, Tuan-Zea Tan, H Phillip Koeffler
Topography of transcriptionally active chromatin in glioblastoma. Science advances 7 (18) (2021)
Humberto Contreras-Trujillo, Jiya Eerdeng, Samir Akre, Du Jiang, Jorge Contreras, Basia Gala, Mary C Vergel-Rodriguez, Yeachan Lee, Aparna Jorapur, Areen Andreasian, Lisa Harton, Charles S Bramlett, Anna Nogalska, Gang Xiao, Jae-Woong Lee, Lai N Chan, Markus Müschen, Akil A Merchant, Rong Lu
Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses. Nature communications 12 (1) (2021)
Lu Yang, Anthony K N Chan, Kazuya Miyashita, Christopher D Delaney, Xi Wang, Hongzhi Li, Sheela Pangeni Pokharel, Sandra Li, Mingli Li, Xiaobao Xu, Wei Lu, Qiao Liu, Nicole Mattson, Kevin Yining Chen, Jinhui Wang, Yate-Ching Yuan, David Horne, Steven T Rosen, Yadira Soto-Feliciano, Zhaohui Feng, Takayuki Hoshii, Gang Xiao, Markus Müschen, Jianjun Chen, Scott A Armstrong, Chun-Wei David Chen
High-resolution characterization of gene function using single-cell CRISPR tiling screen. Nature communications 12 (1) (2021)
Jaewoong Lee, Mark E Robinson, Ning Ma, Dewan Artadji, Mohamed A Ahmed, Gang Xiao, Teresa Sadras, Gauri Deb, Janet Winchester, Kadriye Nehir Cosgun, Huimin Geng, Lai N Chan, Kohei Kume, Teemu P Miettinen, Ye Zhang, Matthew A Nix, Lars Klemm, Chun-Wei David Chen, Jianjun Chen, Vishal Khairnar, Arun P Wiita, Andrei Thomas-Tikhonenko, Michael Farzan, Jae U Jung, David M Weinstock, Scott R Manalis, Michael S. Diamond, Nagarajan Vaidehi, Markus Müschen
IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells. Nature 588 (7838) (2020)
Lai N Chan, Mark A Murakami, Mark E Robinson, Rebecca Caeser, Teresa Sadras, Jaewoong Lee, Kadriye Nehir Cosgun, Kohei Kume, Vishal Khairnar, Gang Xiao, Mohamed A Ahmed, Eamon Aghania, Gauri Deb, Christian Hurtz, Seyedmehdi Shojaee, Chao Hong, Petri Pölönen, Matthew A Nix, Zhengshan Chen, Chun Wei Chen, Jianjun Chen, Andreas Vogt, Merja Heinäniemi, Olli Lohi, Arun P Wiita, Shai Izraeli, Huimin Geng, David M Weinstock, Markus Müschen
Signalling input from divergent pathways subverts B cell transformation. Nature 583 (7818) (2020)
Hend Abdelrasoul, Anila Vadakumchery, Markus Werner, Lennart Lenk, Ahmad Khadour, Marc Young, Omar El Ayoubi, Fotini Vogiatzi, Markus Krämer, Vera Schmid, Zhengshan Chen, Yasar Yousafzai, Gunnar Cario, Martin Schrappe, Markus Müschen, Christina Halsey, Medhanie A Mulaw, Denis Martin Schewe, Elias Hobeika, Ameera Alsadeq, Hassan Jumaa
Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia. Nature communications 11 (1) (2020)
Ye Chen, Liang Xu, Ruby Yu-Tong Lin, Markus Müschen, H Phillip Koeffler
Core transcriptional regulatory circuitries in cancer. Oncogene 39 (43) (2020)
Markus Müschen
Metabolic gatekeepers to safeguard against autoimmunity and oncogenic B cell transformation. Nature reviews. Immunology 19 (5) (2019)
Guillermo Rodríguez-Hernández, Friederike V Opitz, Pilar Delgado, Carolin Walter, Angel F Álvarez-Prado, Inés González-Herrero, Franziska Auer, Ute Fischer, Stefan Janssen, Christoph Bartenhagen, Javier Raboso-Gallego, Ana Casado-García, Alberto Orfao, Oscar Blanco, Diego Alonso López, Javier De Las Rivas, Sara González de Tena-Dávila, Markus Müschen, Martin Dugas, Francisco Javier García Criado, María Begoña García Cenador, Carolina Vicente-Dueñas, Julia Hauer, Almudena R Ramiro, Isidro Sanchez-Garcia, Arndt Borkhardt
Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID. Nature communications 10 (1) (2019)