Juergen Ruland (J Ruland, Jürgen Ruland)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 61

Top Topics

Regulatory T Cells

Top Venues

Nature communications

Nature immunology

European journal of immunology

This page only lists publications with an associated author ORCID identifier.

Publications

Michael Hiltensperger, Juergen Ruland, Kilian Schober
Harnessing naturally occurring mutations for T-cell therapy: a potential new avenue to enhance treatment efficacy. Signal transduction and targeted therapy 9 (1) (2024)
Meiyue Wang, Heinrich Flaswinkel, Abhinav Joshi, Matteo Napoli, Sergi Masgrau-Alsina, Julia M Kamper, Antonia Henne, Alexander Heinz, Marleen Berouti, Niklas A Schmacke, Karsten Hiller, Elisabeth Kremmer, Benedikt Wefers, Wolfgang Wurst, Markus Sperandio, Juergen Ruland, Fröhlich Thomas, Veit Hornung
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation. Nature communications 15 (1) (2024)
Hannah Theobald, David Alejandro Bejarano, N Katzmarski, J Haub, J Schulte-Schrepping, J Yu, Kevin Bassler, A L Ament, C Osei-Sarpong, F Piattini, L Vornholz, W T'Jonck, A H Györfi, H Hayer, X Yu, S Sheoran, A Al Jawazneh, S Chakarov, K Haendler, Gordon D Brown, D L Williams, L Bosurgi, J H W Distler, Florent Ginhoux, Juergen Ruland, Marc Beyer, Melanie Greter, Calum C Bain, A I Vazquez-Armendariz, M Kopf, Joachim L Schultze, Andreas Schlitzer
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation. Nature immunology 25 (6) (2024)
Francis Baumgartner, Stefanos A Bamopoulos, Laura Faletti, Hsiang-Jung Hsiao, Maximilian Holz, Irene Gonzalez-Menendez, Llorenç Boldo, Arik Horne, Sanket Gosavi, Ceren Ozerdem, Nikita Singh, Sven Liebig, Senthilkumar Ramamoorthy, Malte Lehmann, Uta Demel, Anja A Kühl, Tim Wartewig, Juergen Ruland, Frank Thomas Wunderlich, Markus Schick, Wolfgang Walther, Stefan Rose-John, Simon Haas, Leticia Quintanilla-Martinez, Stefan Feske, Stephan Ehl, Rainer Glauben, Ulrich Bernd Keller
Activation of gp130 signaling in T cells drives T H 17-mediated multi-organ autoimmunity. Science signaling 17 (824) (2024)
Hannah Theobald, David Alejandro Bejarano, N Katzmarski, J Haub, J Schulte-Schrepping, J Yu, Kevin Bassler, A L Ament, C Osei-Sarpong, F Piattini, L Vornholz, W T'Jonck, A H Györfi, H Hayer, X Yu, S Sheoran, A Al Jawazneh, S Chakarov, K Haendler, Gordon D Brown, D L Williams, L Bosurgi, J H W Distler, Florent Ginhoux, Juergen Ruland, Marc Beyer, Melanie Greter, Calum C Bain, A I Vazquez-Armendariz, M Kopf, Joachim L Schultze, Andreas Schlitzer
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation. Nature immunology 25 (6) (2024)
Martin Jaeger, Axel Dietschmann, Sophie Austermeier, Sude Dinçer, Pauline Porschitz, Larsen Vornholz, Ralph J A Maas, Evelien G G Sprenkeler, Juergen Ruland, Stefan Wirtz, Tania Azam, Leo A B Joosten, Bernhard Hube, Mihai G Netea, Charles A Dinarello, Mark S Gresnigt
Alpha1-antitrypsin impacts innate host-pathogen interactions with Candida albicans by stimulating fungal filamentation. Virulence 15 (1) (2024)
Francis Baumgartner, Stefanos A Bamopoulos, Laura Faletti, Hsiang-Jung Hsiao, Maximilian Holz, Irene Gonzalez-Menendez, Llorenç Boldo, Arik Horne, Sanket Gosavi, Ceren Ozerdem, Nikita Singh, Sven Liebig, Senthilkumar Ramamoorthy, Malte Lehmann, Uta Demel, Anja A Kühl, Tim Wartewig, Juergen Ruland, Frank Thomas Wunderlich, Markus Schick, Wolfgang Walther, Stefan Rose-John, Simon Haas, Leticia Quintanilla-Martinez, Stefan Feske, Stephan Ehl, Rainer Glauben, Ulrich Bernd Keller
Activation of gp130 signaling in T cells drives T H 17-mediated multi-organ autoimmunity. Science signaling 17 (824) (2024)
Hannah Theobald, David Alejandro Bejarano, N Katzmarski, J Haub, J Schulte-Schrepping, J Yu, Kevin Bassler, A L Ament, C Osei-Sarpong, F Piattini, L Vornholz, W T'Jonck, A H Györfi, H Hayer, X Yu, S Sheoran, A Al Jawazneh, S Chakarov, K Haendler, Gordon D Brown, D L Williams, L Bosurgi, J H W Distler, Florent Ginhoux, Juergen Ruland, Marc Beyer, Melanie Greter, Calum C Bain, A I Vazquez-Armendariz, M Kopf, Joachim L Schultze, Andreas Schlitzer
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation. Nature immunology 25 (6) (2024)
Martin Jaeger, Axel Dietschmann, Sophie Austermeier, Sude Dinçer, Pauline Porschitz, Larsen Vornholz, Ralph J A Maas, Evelien G G Sprenkeler, Juergen Ruland, Stefan Wirtz, Tania Azam, Leo A B Joosten, Bernhard Hube, Mihai G Netea, Charles A Dinarello, Mark S Gresnigt
Alpha1-antitrypsin impacts innate host-pathogen interactions with Candida albicans by stimulating fungal filamentation. Virulence 15 (1) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer (2024)
Meiyue Wang, Heinrich Flaswinkel, Abhinav Joshi, Matteo Napoli, Sergi Masgrau-Alsina, Julia M Kamper, Antonia Henne, Alexander Heinz, Marleen Berouti, Niklas A Schmacke, Karsten Hiller, Elisabeth Kremmer, Benedikt Wefers, Wolfgang Wurst, Markus Sperandio, Juergen Ruland, Fröhlich Thomas, Veit Hornung
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation. Nature communications 15 (1) (2024)
Michael Hiltensperger, Juergen Ruland, Kilian Schober
Harnessing naturally occurring mutations for T-cell therapy: a potential new avenue to enhance treatment efficacy. Signal transduction and targeted therapy 9 (1) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer 5 (1) (2024)
Hannah Theobald, David Alejandro Bejarano, N Katzmarski, J Haub, J Schulte-Schrepping, J Yu, Kevin Bassler, A L Ament, C Osei-Sarpong, F Piattini, L Vornholz, W T'Jonck, A H Györfi, H Hayer, X Yu, S Sheoran, A Al Jawazneh, S Chakarov, K Haendler, Gordon D Brown, D L Williams, L Bosurgi, J H W Distler, Florent Ginhoux, Juergen Ruland, Marc Beyer, Melanie Greter, Calum C Bain, A I Vazquez-Armendariz, M Kopf, Joachim L Schultze, Andreas Schlitzer
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation. Nature immunology (2024)
Francis Baumgartner, Stefanos A Bamopoulos, Laura Faletti, Hsiang-Jung Hsiao, Maximilian Holz, Irene Gonzalez-Menendez, Llorenç Boldo, Arik Horne, Sanket Gosavi, Ceren Ozerdem, Nikita Singh, Sven Liebig, Senthilkumar Ramamoorthy, Malte Lehmann, Uta Demel, Anja A Kühl, Tim Wartewig, Juergen Ruland, Frank Thomas Wunderlich, Markus Schick, Wolfgang Walther, Stefan Rose-John, Simon Haas, Leticia Quintanilla-Martinez, Stefan Feske, Stephan Ehl, Rainer Glauben, Ulrich Bernd Keller
Activation of gp130 signaling in T cells drives T H 17-mediated multi-organ autoimmunity. Science signaling 17 (824) (2024)
Hannah Theobald, David Alejandro Bejarano, N Katzmarski, J Haub, J Schulte-Schrepping, J Yu, Kevin Bassler, A L Ament, C Osei-Sarpong, F Piattini, L Vornholz, W T'Jonck, A H Györfi, H Hayer, X Yu, S Sheoran, A Al Jawazneh, S Chakarov, K Haendler, Gordon D Brown, D L Williams, L Bosurgi, J H W Distler, Florent Ginhoux, Juergen Ruland, Marc Beyer, Melanie Greter, Calum C Bain, A I Vazquez-Armendariz, M Kopf, Joachim L Schultze, Andreas Schlitzer
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation. Nature immunology 25 (6) (2024)
Martin Jaeger, Axel Dietschmann, Sophie Austermeier, Sude Dinçer, Pauline Porschitz, Larsen Vornholz, Ralph J A Maas, Evelien G G Sprenkeler, Juergen Ruland, Stefan Wirtz, Tania Azam, Leo A B Joosten, Bernhard Hube, Mihai G Netea, Charles A Dinarello, Mark S Gresnigt
Alpha1-antitrypsin impacts innate host-pathogen interactions with Candida albicans by stimulating fungal filamentation. Virulence 15 (1) (2024)
Hannah Theobald, David Alejandro Bejarano, N Katzmarski, J Haub, J Schulte-Schrepping, J Yu, Kevin Bassler, A L Ament, C Osei-Sarpong, F Piattini, L Vornholz, W T'Jonck, A H Györfi, H Hayer, X Yu, S Sheoran, A Al Jawazneh, S Chakarov, K Haendler, Gordon D Brown, D L Williams, L Bosurgi, J H W Distler, Florent Ginhoux, Juergen Ruland, Marc Beyer, Melanie Greter, Calum C Bain, A I Vazquez-Armendariz, M Kopf, Joachim L Schultze, Andreas Schlitzer
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation. Nature immunology 25 (6) (2024)
Lisa Pfeuffer, Viola Siegert, Julia Frede, Leonie Rieger, Riccardo Trozzo, Niklas de Andrade Krätzig, Sandra Ring, Shamim Sarhadi, Nicole Beck, Stefan Niedermeier, Mar Abril-Gil, Mohamed Elbahloul, Marianne Remke, Katja Steiger, Ruth Eichner, Julia Jellusova, Roland Rad, Florian Bassermann, Christof Winter, Juergen Ruland, Maike Buchner
B-cell intrinsic RANK signaling cooperates with TCL1 to induce lineage-dependent B-cell transformation. Blood cancer journal 14 (1) (2024)
Julia Höbart, Juergen Ruland
Constructing co-stimulation to boost TCR therapy. Nature cancer 5 (5) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer 5 (1) (2024)
Lisa Pfeuffer, Viola Siegert, Julia Frede, Leonie Rieger, Riccardo Trozzo, Niklas de Andrade Krätzig, Sandra Ring, Shamim Sarhadi, Nicole Beck, Stefan Niedermeier, Mar Abril-Gil, Mohamed Elbahloul, Marianne Remke, Katja Steiger, Ruth Eichner, Julia Jellusova, Roland Rad, Florian Bassermann, Christof Winter, Juergen Ruland, Maike Buchner
B-cell intrinsic RANK signaling cooperates with TCL1 to induce lineage-dependent B-cell transformation. Blood cancer journal 14 (1) (2024)
Martin Jaeger, Axel Dietschmann, Sophie Austermeier, Sude Dinçer, Pauline Porschitz, Larsen Vornholz, Ralph J A Maas, Evelien G G Sprenkeler, Juergen Ruland, Stefan Wirtz, Tania Azam, Leo A B Joosten, Bernhard Hube, Mihai G Netea, Charles A Dinarello, Mark S Gresnigt
Alpha1-antitrypsin impacts innate host-pathogen interactions with Candida albicans by stimulating fungal filamentation. Virulence 15 (1) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer 5 (1) (2024)
Hannah Theobald, David Alejandro Bejarano, N Katzmarski, J Haub, J Schulte-Schrepping, J Yu, Kevin Bassler, A L Ament, C Osei-Sarpong, F Piattini, L Vornholz, W T'Jonck, A H Györfi, H Hayer, X Yu, S Sheoran, A Al Jawazneh, S Chakarov, K Haendler, Gordon D Brown, D L Williams, L Bosurgi, J H W Distler, Florent Ginhoux, Juergen Ruland, Marc Beyer, Melanie Greter, Calum C Bain, A I Vazquez-Armendariz, M Kopf, Joachim L Schultze, Andreas Schlitzer
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation. Nature immunology 25 (6) (2024)
Hannah Theobald, David Alejandro Bejarano, N Katzmarski, J Haub, J Schulte-Schrepping, J Yu, Kevin Bassler, A L Ament, C Osei-Sarpong, F Piattini, L Vornholz, W T'Jonck, A H Györfi, H Hayer, X Yu, S Sheoran, A Al Jawazneh, S Chakarov, K Haendler, Gordon D Brown, D L Williams, L Bosurgi, J H W Distler, Florent Ginhoux, Juergen Ruland, Marc Beyer, Melanie Greter, Calum C Bain, A I Vazquez-Armendariz, M Kopf, Joachim L Schultze, Andreas Schlitzer
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation. Nature immunology 25 (6) (2024)
Martin Jaeger, Axel Dietschmann, Sophie Austermeier, Sude Dinçer, Pauline Porschitz, Larsen Vornholz, Ralph J A Maas, Evelien G G Sprenkeler, Juergen Ruland, Stefan Wirtz, Tania Azam, Leo A B Joosten, Bernhard Hube, Mihai G Netea, Charles A Dinarello, Mark S Gresnigt
Alpha1-antitrypsin impacts innate host-pathogen interactions with Candida albicans by stimulating fungal filamentation. Virulence 15 (1) (2024)
Meiyue Wang, Heinrich Flaswinkel, Abhinav Joshi, Matteo Napoli, Sergi Masgrau-Alsina, Julia M Kamper, Antonia Henne, Alexander Heinz, Marleen Berouti, Niklas A Schmacke, Karsten Hiller, Elisabeth Kremmer, Benedikt Wefers, Wolfgang Wurst, Markus Sperandio, Juergen Ruland, Fröhlich Thomas, Veit Hornung
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation. Nature communications 15 (1) (2024)
Michael Hiltensperger, Juergen Ruland, Kilian Schober
Harnessing naturally occurring mutations for T-cell therapy: a potential new avenue to enhance treatment efficacy. Signal transduction and targeted therapy 9 (1) (2024)
Emma Morrish, Tim Wartewig, Andreas Kratzert, Marc Rosenbaum, Katja Steiger, Juergen Ruland
The fusion oncogene VAV1-MYO1F triggers aberrant T-cell receptor signaling in vivo and drives peripheral T-cell lymphoma in mice. European journal of immunology 53 (3) (2023)
Emma Morrish, Tim Wartewig, Andreas Kratzert, Marc Rosenbaum, Katja Steiger, Juergen Ruland
The fusion oncogene VAV1-MYO1F triggers aberrant T-cell receptor signaling in vivo and drives peripheral T-cell lymphoma in mice. European journal of immunology 53 (3) (2023)
Tim Wartewig, Jay C Daniels, Miriam Schulz, Erik Hameister, Abhinav Joshi, Joonhee Park, Emma Morrish, Anuroop Venkateswaran Venkatasubramani, Filippo M Cernilogar, Frits H A van Heijster, Christian Hundshammer, Heike Schneider, Filippos Konstantinidis, Judith V Gabler, Christine Klement, Henry Kurniawan, Calvin Law, Yujin Lee, Sara Choi, Joan Guitart, Ignasi Forne, Jérôme Giustinani, Markus Müschen, Salvia Jain, David M Weinstock, Roland Rad, Nicolas Ortonne, Franz Schilling, Gunnar Schotta, Axel Imhof, Dirk Brenner, Jaehyuk Choi, Juergen Ruland
PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma. Nature cancer (2023)
Emma Morrish, Tim Wartewig, Andreas Kratzert, Marc Rosenbaum, Katja Steiger, Juergen Ruland
The fusion oncogene VAV1-MYO1F triggers aberrant T-cell receptor signaling in vivo and drives peripheral T-cell lymphoma in mice. European journal of immunology 53 (3) (2023)
Larsen Vornholz, Sophie E Isay, Zsuzsanna Kurgyis, Daniel C Strobl, Patricia Loll, Mohammed H Mosa, Malte Daniel Luecken, Michael Sterr, Heiko Lickert, Christof Winter, Florian R Greten, Henner F Farin, Fabian Joachim Theis, Juergen Ruland
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy. Science advances 9 (11) (2023)
Larsen Vornholz, Sophie E Isay, Zsuzsanna Kurgyis, Daniel C Strobl, Patricia Loll, Mohammed H Mosa, Malte Daniel Luecken, Michael Sterr, Heiko Lickert, Christof Winter, Florian R Greten, Henner F Farin, Fabian Joachim Theis, Juergen Ruland
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy. Science advances 9 (11) (2023)
Larsen Vornholz, Sophie E Isay, Zsuzsanna Kurgyis, Daniel C Strobl, Patricia Loll, Mohammed H Mosa, Malte Daniel Luecken, Michael Sterr, Heiko Lickert, Christof Winter, Florian R Greten, Henner F Farin, Fabian Joachim Theis, Juergen Ruland
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy. Science advances 9 (11) (2023)
Larsen Vornholz, Sophie E Isay, Zsuzsanna Kurgyis, Daniel C Strobl, Patricia Loll, Mohammed H Mosa, Malte Daniel Luecken, Michael Sterr, Heiko Lickert, Christof Winter, Florian R Greten, Henner F Farin, Fabian Joachim Theis, Juergen Ruland
Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy. Science advances 9 (11) (2023)
Jana Zecha, Florian P Bayer, Svenja Wiechmann, Julia Woortman, Nicola Berner, Julian Müller, Annika Schneider, Karl Kramer, Mar Abril-Gil, Thomas A Hopf, Leonie Reichart, Lin Chen, Fynn M Hansen, Severin Lechner, Patroklos Samaras, Stephan Eckert, Ludwig Lautenbacher, Maria Reinecke, Firas Hamood, Polina Prokofeva, Larsen Vornholz, Chiara Falcomatà, Madeleine Dorsch, Ayla Schröder, Anton Venhuizen, Stephanie Wilhelm, Guillaume Médard, Gabriele Stoehr, Juergen Ruland, Barbara M Grüner, Dieter Saur, Maike Buchner, Benjamin Ruprecht, Hannes Hahne, Matthew The, Mathias Wilhelm, Bernhard Kuster
Decrypting drug actions and protein modifications by dose- and time-resolved proteomics. Science (New York, N.Y.) (2023)
Emma Morrish, Tim Wartewig, Andreas Kratzert, Marc Rosenbaum, Katja Steiger, Juergen Ruland
The fusion oncogene VAV1-MYO1F triggers aberrant T-cell receptor signaling in vivo and drives peripheral T-cell lymphoma in mice. European journal of immunology (2022)
Tanja Groll, Miguel G Silva, Rim Sabrina Jahan Sarker, Markus Tschurtschenthaler, Theresa Schnalzger, Carolin Mogler, Daniela Denk, Sebastian Schölch, Barbara U Schraml, Juergen Ruland, Roland Rad, Dieter Saur, Wilko Weichert, Moritz Jesinghaus, Kaspar Matiasek, Katja Steiger
Comparative Study of the Role of Interepithelial Mucosal Mast Cells in the Context of Intestinal Adenoma-Carcinoma Progression. Cancers 14 (9) (2022)
Emma Morrish, Juergen Ruland
Cytotoxic FCER1G + innate-like T cells: new potential for tumour immunotherapy. Signal transduction and targeted therapy 7 (1) (2022)
Nina Koerber, Alina Priller, Sarah Yazici, Tanja Bauer, Cho-Chin Cheng, Hrvoje Mijočević, Hannah Wintersteller, Samuel Jeske, Emanuel Vogel, Martin Feuerherd, Kathrin Tinnefeld, Christof Winter, Juergen Ruland, Markus Gerhard, Bernhard Haller, Catharina Christa, Otto Zelger, Hedwig Roggendorf, Martin Halle, Johanna Erber, Paul Lingor, Oliver T Keppler, Dietmar Zehn, Ulrike Protzer, Percy A Knolle
Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents. Nature communications 13 (1) (2022)
Emma Morrish, Tim Wartewig, Andreas Kratzert, Marc Rosenbaum, Katja Steiger, Juergen Ruland
The fusion oncogene VAV1-MYO1F triggers aberrant T-cell receptor signaling in vivo and drives peripheral T-cell lymphoma in mice. European journal of immunology (2022)
Emma Morrish, Tim Wartewig, Andreas Kratzert, Marc Rosenbaum, Katja Steiger, Juergen Ruland
The fusion oncogene VAV1-MYO1F triggers aberrant T-cell receptor signalling in vivo and drives peripheral T-cell lymphoma in mice. European journal of immunology (2022)
Marc Rosenbaum, Theresa Schnalzger, Thomas Engleitner, Christin Weiß, Ritu Mishra, Cora Mibus, Theresa Mitterer, Roland Rad, Juergen Ruland
MALT1 protease function in regulatory T cells induces MYC activity to promote mitochondrial function and cellular expansion. European journal of immunology (2021)
Veronika Ecker, Martina Stumpf, Lisa Brandmeier, Tanja Neumayer, Lisa Pfeuffer, Thomas Engleitner, Ingo Ringshausen, Nina Nelson, Manfred Jücker, Stefan Wanninger, Thorsten Zenz, Clemens Wendtner, Katrin Manske, Katja Steiger, Roland Rad, Markus Müschen, Juergen Ruland, Maike Buchner
Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia. Nature communications 12 (1) (2021)
Melissa Klug, Kilian Kirmes, Jiaying Han, Olga E Lazareva, Marc Rosenbaum, Giacomo Viggiani, Moritz von Scheidt, Juergen Ruland, Jan Baumbach, Gianluigi Condorelli, Karl-Ludwig Laugwitz, Markus List, Isabell Bernlochner, Dario Bongiovanni
Mass cytometry of platelet-rich plasma: a new approach to analyze platelet surface expression and reactivity. Platelets 33 (6) (2021)
Adam Wahida, Madeleine Müller, Andreas Hiergeist, Bastian Popper, Katja Steiger, Caterina Branca, Markus Tschurtschenthaler, Thomas Engleitner, Sainitin Donakonda, Jordy De Coninck, Rupert Öllinger, Marie K Pfautsch, Nicole Müller, Miguel G Silva, Sinem Usluer, Erik Thiele Orberg, Jan P Böttcher, Nicole Pfarr, Martina Anton, Julia B Slotta-Huspenina, Andreas G Nerlich, Tobias Madl, Marijana Basic, Marijana Basic, Geert Berx, Juergen Ruland, Percy A Knolle, Roland Rad, Timon E Adolph, Peter Vandenabeele, Hirokazu Kanegane, André Gessner, Philipp J Jost, Monica Yabal
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells. Science immunology 6 (65) (2021)
Tobias F Dreyer, Sabine Kuhn, Christoph Stange, Nadine Heithorst, Daniela Schilling, Jil Jelsma, Wolfgang Sievert, Stefanie Seitz, Stefan Stangl, Alexander Hapfelmeier, Aurelia Noske, Anja Kathrin Wege, Wilko Weichert, Juergen Ruland, Manfred Schmitt, Julia Dorn, Marion Kiechle, Ute Reuning, Viktor Magdolen, Gabriele Multhoff, Holger Bronger
The Chemokine CX3CL1 Improves Trastuzumab Efficacy in HER2 Low-Expressing Cancer In Vitro and In Vivo. Cancer immunology research 9 (7) (2021)
Theresa Landspersky, Mehmet Saçma, Jennifer Rivière, Judith S Hecker, Franziska Hettler, Erik Hameister, Katharina Brandstetter, Rouzanna Istvanffy, Sandra Romero Marquez, Romina Ludwig, Marilena Götz, Michèle Constanze Buck, Martin Wolf, Matthias Schiemann, Juergen Ruland, Dirk Strunk, Akiko Shimamura, Kasiani C Myers, Terry P Yamaguchi, Matthias Kieslinger, Heinrich Leonhardt, Florian Bassermann, Katharina S Götze, Hartmut Geiger, Christina Schreck, Robert A J Oostendorp
Autophagy In Mesenchymal Progenitors Protects Mice Against Bone Marrow Failure After Severe Intermittent Stress. Blood (2021)
Zsuzsanna Kurgyis, Larsen Vornholz, Konstanze Pechloff, Lajos Vince Kemény, Tim Wartewig, Andreas Muschaweckh, Abhinav Joshi, Katja Kranen, Lara Hartjes, Sigrid Möckel, Katja Steiger, Erik Hameister, Thomas Volz, Steve Pascolo, Lars Einar French, Tilo Biedermann, Thomas Korn, Juergen Ruland
Keratinocyte-intrinsic BCL10/MALT1 activity initiates and amplifies psoriasiform skin inflammation. Science immunology 6 (65) (2021)
Thomas J O'Neill, Thomas Seeholzer, Andreas Gewies, Torben Gehring, Florian Giesert, Isabel Hamp, Carina Graß, Henrik Schmidt, Katharina Kriegsmann, Marie J Tofaute, Katrin Demski, Tanja Poth, Marc Rosenbaum, Theresa Schnalzger, Juergen Ruland, Martin Göttlicher, Mark Kriegsmann, Ronald Naumann, Vigo Heissmeyer, Oliver Plettenburg, Wolfgang Wurst, Daniel Krappmann
TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease. Science immunology 6 (65) (2021)
Joonhee Park, Jay C Daniels, Tim Wartewig, Kimberly G Ringbloom, Maria Estela Martinez Escala, Sara Choi, Jane J Thomas, Peter G Doukas, Jingyi Yang, Caroline Snowden, Calvin Law, Yujin Lee, Katie Lee, Yancong Zhang, Carly Conran, Kyle Tegtmeyer, Samuel H Mo, David Randall Pease, Balaji Jothishankar, Pui-Yan Kwok, Farah R Abdulla, Barbara Pro, Abner Louissaint, Titus J Boggon, Jeffrey Sosman, Joan Guitart, Deepak A Rao, Juergen Ruland, Jaehyuk Choi
Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity. Blood 138 (14) (2021)
Simon Heidegger, Alexander Wintges, Florian Stritzke, Sarah Bek, Katja Steiger, Paul-Albert Koenig, Sascha Göttert, Thomas Engleitner, Rupert Öllinger, Tatiana Nedelko, Julius Clemens Fischer, Vladimir Makarov, Christof Winter, Roland Rad, Marcel R M van den Brink, Juergen Ruland, Florian Bassermann, Timothy A Chan, Tobias Haas, Hendrik Poeck
RIG-I activation is critical for responsiveness to checkpoint blockade. Science immunology 4 (39) (2020)
Enkhtsetseg Munkhbaatar, Michelle Dietzen, Deepti Agrawal, Martina Anton, Moritz Jesinghaus, Melanie Boxberg, Nicole Pfarr, Pidassa Bidola, Sebastian Uhrig, Ulrike Höckendorf, Anna-Lena Meinhardt, Adam Wahida, Irina Heid, Rickmer F Braren, Ritu Mishra, Arne Warth, Thomas Muley, Patrina S P Poh, Xin Wang, Stefan Fröhling, Katja Steiger, Julia Slotta-Huspenina, Martijn van Griensven, Franz Pfeiffer, Sebastian Lange, Roland Rad, Magda Spella, Georgios T Stathopoulos, Juergen Ruland, Florian Bassermann, Wilko Weichert, Andreas Strasser, Caterina Branca, Mathias F Heikenwälder, Charles Swanton, Nicholas McGranahan, Philipp J Jost
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically. Nature communications 11 (1) (2020)
Juergen Ruland, Lara Hartjes
CARD-BCL-10-MALT1 signalling in protective and pathological immunity. Nature reviews. Immunology 19 (2) (2019)
Marc Rosenbaum, Andreas Gewies, Konstanze Pechloff, Christoph Heuser, Thomas Engleitner, Torben Gehring, Lara Hartjes, Sabrina Krebs, Daniel Krappmann, Mark Kriegsmann, Wilko Weichert, Roland Rad, Christian Kurts, Juergen Ruland
Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells. Nature communications 10 (1) (2019)
Lydia Kasper, Annika König, Paul-Albert Koenig, Mark S Gresnigt, Johannes Westman, Rebecca A Drummond, Michail S Lionakis, Olaf Groß, Juergen Ruland, Julian R Naglik, Bernhard Hube
The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes. Nature communications 9 (1) (2018)
Beate Hagl, Benedikt D Spielberger, Silvia Thoene, Sophie Bonnal, Christian Mertes, Christof Winter, Isaac J Nijman, Shira Verduin, Andreas C Eberherr, Anne Puel, Detlev Schindler, Juergen Ruland, Thomas Meitinger, Julien Gagneur, Jordan S Orange, Marielle E van Gijn, Ellen D Renner
Somatic alterations compromised molecular diagnosis of DOCK8 hyper-IgE syndrome caused by a novel intronic splice site mutation. Scientific reports 8 (1) (2018)
Susan Klaeger, Stephanie Wilhelm, Mathias Wilhelm, Harald Polzer, Binje Vick, Paul-Albert Koenig, Maria Reinecke, Benjamin Ruprecht, Svenja Petzoldt, Chen Meng, Jana Zecha, Katrin Reiter, Huichao Qiao, Dominic Helm, Heiner Koch, Melanie Schoof, Giulia Canevari, Elena Casale, Stefania Re Depaolini, Annette Feuchtinger, Zhixiang Wu, Tobias K Schmidt, Lars Rueckert, Wilhelm Becker, Jan Huenges, Anne-Kathrin Garz, Bjoern-Oliver Gohlke, Daniel Paul Zolg, Gian Kayser, Tonu Vooder, Robert Preissner, Hannes Hahne, Neeme Tõnisson, Karl Kramer, Katharina Götze, Florian Bassermann, Judith Schlegl, Hans-Christian Ehrlich, Stephan Aiche, Axel Walch, Philipp A Greif, Sabine Schneider, Eduard Rudolf Felder, Juergen Ruland, Guillaume Médard, Irmela Jeremias, Karsten Spiekermann, Bernhard Kuster
The target landscape of clinical kinase drugs. Science (New York, N.Y.) 358 (6367) (2018)