Martin Empting

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 27

Top Venues

Nature communications

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

ChemMedChem

ACS chemical biology

Helmholtz Institute for Pharmaceutical Research Saarland

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Helmholtz Institute for Pharmaceutical Research Saarland Jan 01 2017

Germany

Habilitant/Project Leader :: Drug Design and Optimization

Helmholtz Institute for Pharmaceutical Research Saarland Jan 01 2013

Germany

PostDoc :: Drug Design & Optimization

Publications

Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Noha Nafee, Dina M Gaber, Alaa Abouelfetouh, Mustafa Alseqely, Martin Empting, Marc Schneider
Enzyme-Linked Lipid Nanocarriers for Coping Pseudomonal Pulmonary Infection. Would Nanocarriers Complement Biofilm Disruption or Pave Its Road? International journal of nanomedicine 19 (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Noha Nafee, Dina M Gaber, Alaa Abouelfetouh, Mustafa Alseqely, Martin Empting, Marc Schneider
Enzyme-Linked Lipid Nanocarriers for Coping Pseudomonal Pulmonary Infection. Would Nanocarriers Complement Biofilm Disruption or Pave Its Road? International journal of nanomedicine 19 (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Svenja M Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K Chatterjee, Kristen A Johnson, Kaycie Morwood, Katharina Rox, Walid A M Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna Katharina Herta Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Nature communications 15 (1) (2024)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (5) (2023)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (5) (2023)
Aylin Berwanger, Saskia C Stein, Andreas Martin Kany, Melissa Gartner, Brigitta Loretz, Claus-Michael Lehr, Anna Katharina Herta Hirsch, Thomas F Schulz, Martin Empting
Disrupting Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor. Journal of medicinal chemistry (2023)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023)
Mostafa M Hamed, Ahmed S Abdelsamie, Katharina Rox, Christian Schütz, Andreas Martin Kany, Teresa Röhrig, Stefan Schmelz, Wulf Blankenfeldt, Alejandro Arce Rodriguez, José Manuel Borrero-de Acuña, Dieter Jahn, Jessica Rademacher, Felix C C Ringshausen, Nina Cramer, Burkhard Tümmler, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Martin Empting
Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10 (5) (2023)
Aylin Berwanger, Martin Empting
KSHV-specific antivirals targeting the protein-DNA interaction of the latency-associated nuclear antigen. Future medicinal chemistry 13 (13) (2021)
Christian Schütz, Duy-Khiet Ho, Mostafa Mohamed Hamed, Ahmed Saad Abdelsamie, Teresa Röhrig, Christian Herr, Andreas Martin Kany, Katharina Rox, Stefan Schmelz, Lorenz Siebenbürger, Marius Wirth, Carsten Börger, Samir Yahiaoui, Robert Bals, Andrea Scrima, Wulf Blankenfeldt, Justus Constantin Horstmann, Rebekka Christmann, Xabier Murgia, Marcus Koch, Aylin Berwanger, Brigitta Loretz, Anna Katharina Herta Hirsch, Rolf Wolfgang Hartmann, Claus-Michael Lehr, Martin Empting
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 8 (12) (2021)
Philine Kirsch, Valentin Jakob, Walid A M Elgaher, Christine Walt, Kevin Oberhausen, Thomas F Schulz, Martin Empting
Discovery of Novel Latency-Associated Nuclear Antigen Inhibitors as Antiviral Agents Against Kaposi's Sarcoma-Associated Herpesvirus. ACS chemical biology 15 (2) (2020)
Ahmed Ashraf Moustafa Kamal, Monica Habib, Joerg Haupenthal, Rolf Wolfgang Hartmann, Martin Empting
Hit evaluation of an α-helical peptide: Ala-scan, truncation and sidechain-to-sidechain macrocyclization of an RNA polymerase Inhibitor. Biological chemistry 400 (3) (2019)
Alexander Kiefer, Chantal D Bader, Jana Held, Anna Esser, Jan Rybniker, Martin Empting, Daniel Krug, Uli Kazmaier
Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (37) (2019)
Michael Zender, Florian Witzgall, Alexander Kiefer, Benjamin Kirsch, Christine K Maurer, Andreas Martin Kany, Ningna Xu, Stefan Schmelz, Carsten Börger, Wulf Blankenfeldt, Martin Empting
Flexible Fragment Growing Boosts Potency of Quorum-Sensing Inhibitors against Pseudomonas aeruginosa Virulence. ChemMedChem 15 (2) (2019)
Philine Kirsch, Valentin Jakob, Kevin Oberhausen, Saskia C Stein, Ivano Cucarro, Thomas F Schulz, Martin Empting
Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8. Journal of medicinal chemistry 62 (8) (2019)
Andreas Martin Kany, Asfandyar Sikandar, Samir Yahiaoui, Jörg Haupenthal, Isabell Walter, Martin Empting, Jesko Koehnke, Rolf Wolfgang Hartmann
Tackling Pseudomonas aeruginosa Virulence by a Hydroxamic Acid-Based LasB Inhibitor. ACS chemical biology 13 (9) (2018)
Christian Schütz, Martin Empting
Targeting the Pseudomonas quinolone signal quorum sensing system for the discovery of novel anti-infective pathoblockers. Beilstein journal of organic chemistry 14 (2018)
Florian Witzgall, Tobias Depke, Michael Hoffmann, Martin Empting, Mark Brönstrup, Daniel Krug, Wulf Blankenfeldt
The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC. Chembiochem : a European journal of chemical biology 19 (14) (2018)
Florian Graef, Robert Richter, Verena Fetz, Xabier Murgia, Chiara De Rossi, Nicole Schneider-Daum, Giuseppe Allegretta, Walid Elgaher, Jörg Haupenthal, Martin Empting, Felix Beckmann, Mark Brönstrup, Rolf Wolfgang Hartmann, Sarah Gordon, Claus-Michael Lehr
In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics. ACS infectious diseases 4 (8) (2018)
Christian Brengel, Andreas Thomann, Alexander Schifrin, Giuseppe Allegretta, Ahmed A M Kamal, Jörg Haupenthal, Isabell Schnorr, Sang Hyun Cho, Scott G Franzblau, Martin Empting, Jens Eberhard, Rolf W Hartmann
Biophysical Screening of a Focused Library for the Discovery of CYP121 Inhibitors as Novel Antimycobacterials. ChemMedChem 12 (19) (2017)
Doreen Könning, Laura Rhiel, Martin Empting, Julius Grzeschik, Carolin Sellmann, Christian Schröter, Stefan Zielonka, Stephan Dickgießer, Thomas Pirzer, Desislava Yanakieva, Stefan Becker, Harald Kolmar
Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic binders. Scientific reports 7 (1) (2017)
Andreas Thomann, Christian Brengel, Carsten Börger, Dagmar Kail, Anke Steinbach, Martin Empting, Rolf W Hartmann
Structure-Activity Relationships of 2-Sufonylpyrimidines as Quorum-Sensing Inhibitors to Tackle Biofilm Formation and eDNA Release of Pseudomonas aeruginosa. ChemMedChem 11 (22) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Martin Empting