Jesko Koehnke (Jesko Köhnke)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 19

Top Venues

Journal of the American Chemical Society

ACS chemical biology

Nature chemical biology

Natural product reports

Universität des Saarlandes

Columbia University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Universität des Saarlandes Aug 8o 2018

Germany

Associated Junior Professor :: Stuctural Biology

Education History

Columbia University Sep 1o 2005 - Feb 10o 2010

United States

PHD :: Biochemistry and Molecular Biophysics

Publications

Sebastian Adam, Dazhong Zheng, Andreas Klein, Carsten Volz, William Mullen, Sally L Shirran, Brian O Smith, Olga V Kalinina, Rolf Müller, Jesko Koehnke
Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis. Nature chemistry (2023)
Jesko Koehnke
Caught in the act. Nature chemical biology (2022)
Asfandyar Sikandar, Maria Lopatniuk, Andriy Luzhetskyy, Rolf Müller, Jesko Koehnke
Total In Vitro Biosynthesis of the Thioamitide Thioholgamide and Investigation of the Pathway. Journal of the American Chemical Society 144 (11) (2022)
Laura Franz, Uli Kazmaier, Andrew W Truman, Jesko Koehnke
Bottromycins - biosynthesis, synthesis and activity. Natural product reports 38 (9) (2021)
Isabell Walter, Sebastian Adam, Maria Virginia Gentilini, Andreas Martin Kany, Christian Brengel, Andreas Thomann, Tim Sparwasser, Jesko Koehnke, Rolf W Hartmann
Structure-Activity Relationship and Mode-Of-Action Studies Highlight 1-(4-Biphenylylmethyl)-1H-imidazole-Derived Small Molecules as Potent CYP121 Inhibitors. ChemMedChem 16 (18) (2021)
Laura Franz, Jesko Koehnke
Leader peptide exchange to produce hybrid, new-to-nature ribosomal natural products. Chemical communications (Cambridge, England) 57 (52) (2021)
Asfandyar Sikandar, Maria Lopatniuk, Andriy Luzhetskyy, Jesko Koehnke
Non-Heme Monooxygenase ThoJ Catalyzes Thioholgamide β-Hydroxylation. ACS chemical biology 15 (10) (2020)
Joachim J Hug, Jan Dastbaz, Sebastian Adam, Ole Revermann, Jesko Koehnke, Daniel Krug, Rolf Müller
Biosynthesis of Cittilins, Unusual Ribosomally Synthesized and Post-translationally Modified Peptides from Myxococcus xanthus. ACS chemical biology 15 (8) (2020)
Sebastian Adam, Laura Franz, Mohammed Milhim, Rita Bernhardt, Olga V Kalinina, Jesko Koehnke
Characterization of the Stereoselective P450 Enzyme BotCYP Enables the In Vitro Biosynthesis of the Bottromycin Core Scaffold. Journal of the American Chemical Society 142 (49) (2020)
Alexander Axer, Ravindra P Jumde, Sebastian Adam, Andreas Faust, Michael Schäfers, Manfred Fobker, Jesko Koehnke, Anna Katharina Herta Hirsch, Ryan Gilmour
Enhancing glycan stability via site-selective fluorination: modulating substrate orientation by molecular design. Chemical science 12 (4) (2020)
Asfandyar Sikandar, Laura Franz, Sebastian Adam, Javier Santos-Aberturas, Liliya Horbal, Andriy Luzhetskyy, Andrew W Truman, Olga V Kalinina, Jesko Koehnke
The bottromycin epimerase BotH defines a group of atypical α/β-hydrolase-fold enzymes. Nature chemical biology 16 (9) (2020)
Asfandyar Sikandar, Laura Franz, Okke Melse, Iris Antes, Jesko Koehnke
Thiazoline-Specific Amidohydrolase PurAH Is the Gatekeeper of Bottromycin Biosynthesis. Journal of the American Chemical Society 141 (25) (2019)
Andreas Martin Kany, Asfandyar Sikandar, Samir Yahiaoui, Jörg Haupenthal, Isabell Walter, Martin Empting, Jesko Koehnke, Rolf Wolfgang Hartmann
Tackling Pseudomonas aeruginosa Virulence by a Hydroxamic Acid-Based LasB Inhibitor. ACS chemical biology 13 (9) (2018)
Andreas Martin Kany, Asfandyar Sikandar, Jörg Haupenthal, Samir Yahiaoui, Christine K Maurer, Ewgenij Proschak, Jesko Koehnke, Rolf Wolfgang Hartmann
Binding Mode Characterization and Early in Vivo Evaluation of Fragment-Like Thiols as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa. ACS infectious diseases 4 (6) (2018)
Asfandyar Sikandar, Katarina Cirnski, Giambattista Testolin, Carsten Volz, Mark Brönstrup, Olga V Kalinina, Rolf Müller, Jesko Koehnke
Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA. Journal of the American Chemical Society 140 (48) (2018)
Louise Kjaerulff, Asfandyar Sikandar, Nestor Zaburannyi, Sebastian Adam, Jennifer Herrmann, Jesko Koehnke, Rolf Müller
Thioholgamides: Thioamide-Containing Cytotoxic RiPP Natural Products. ACS chemical biology 12 (11) (2017)
Laura Franz, Sebastian Adam, Javier Santos-Aberturas, Andrew W Truman, Jesko Koehnke
Macroamidine Formation in Bottromycins Is Catalyzed by a Divergent YcaO Enzyme. Journal of the American Chemical Society 139 (50) (2017)
Chengzhang Fu, Asfandyar Sikandar, Jannik Donner, Nestor Zaburannyi, Jennifer Herrmann, Michael Reck, Irene Wagner-Döbler, Jesko Koehnke, Rolf Müller
The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD. Nature communications 8 (1) (2017)
Greg Mann, Liujie Huo, Sebastian Adam, Brunello Nardone, Jeremie Vendome, Nicholas James Westwood, Rolf Müller, Jesko Koehnke
Structure and Substrate Recognition of the Bottromycin Maturation Enzyme BotP. Chembiochem : a European journal of chemical biology 17 (23) (2016)

Jesko Koehnke.css-eqlu8i{font-size:small;padding-left:4px;} (Jesko Köhnke)

Publication Activity (10 Years)

Top Topics

Top Venues

Jesko Koehnke (Jesko Köhnke)